Migration of arterial wall cells: Expression of plasminogen activators and inhibitors in injured rat arteries

Circulation Research

Volumn 78, Issue 3, 1996, Pages 405-414

  Reidy, Michael A ^a   Irvin, Colleen ^a   Lindner, Volkhard ^b  

^a UNIVERSITY OF WASHINGTON   (United States)

^b Maine Medical Center Research Institute   (United States)

Author keywords

arterial injury; endothelium; plasminogen activators; smooth muscle cells

Indexed keywords

CASEIN; PLASMIN; PLASMINOGEN ACTIVATOR; PLASMINOGEN ACTIVATOR INHIBITOR; PLASMINOGEN ACTIVATOR INHIBITOR 1; TISSUE PLASMINOGEN ACTIVATOR; UROKINASE;

ANIMAL MODEL; ANIMAL TISSUE; ARTERY INJURY; ARTERY WALL; ARTICLE; CELL MIGRATION; CONTROLLED STUDY; FIBRINOLYSIS; GENE EXPRESSION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; VASCULAR ENDOTHELIUM; VASCULAR SMOOTH MUSCLE;

EID: 0030057694     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.78.3.405     Document Type: Article

References (51)

1. Levin EG, Loskutoff DJ. Cultured bovine endothelial cells produce both urokinase and tissue-type plasminogen activators. J Cell Biochem. 1982;94:631-636.
2. Moscatelli D. Urokinase-type and tissue-type plasminogen activators have different distributions in cultured capillary endothelial cells. J Cell Biochem. 1986;30:19-29.
3. Pepper MS, Vassalli J-D, Montesano R, Orci L. Urokinase-type plasminogen activator is induced in migrating capillary endothelial cells. J Cell Biol. 1987;105:2535-2541.
4. Pepper MS, Sappino AP, Stöcklin R, Montesano R, Orci L, Vassalli J-D. Upregulation of urokinase receptor expression on migrating endothelial cells. J Cell Biol. 1993;122:673-684.
5. Saksela O, Rifkin DB. Cell-associated plasminogen activation: regulation and physiological functions. Annu Rev Cell Biol. 1988;4: 93-126.
6. Danø K, Andreasen PA, Grondahl-Hansen J, Kristensen P, Nielsen LS, Skriver L. Plasminogen activators, tissue degradation and cancer. Adv Cancer Res. 1985;44:139-266.
7. Goldfarb LH, Liotta LA. Proteolytic enzymes in cancer invasion and metastasis. Semin Thromb Hemost. 1986;12:294-307.
8. Ossowski L. Plasminogen activator dependent pathways in the dissemination of human tumor cells in the chick embryo. Cell. 1988;52: 321-328.
9. Ossowski L, Reich E. Antibodies to plasminogen activator inhibit human tumor metastasis. Cell. 1983;35:611-619.
10. Estreicher A, Mühlhauser J, Carpentier JL, Orci L, Vassalli J-D. The receptor for urokinase type plasminogen activator polarizes expression of the protease to the leading edge of migrating monocytes and promotes degradation of enzyme inhibitor complexes. J Cell Biol. 1990;111:783-792.
11. r 55,000 form of the human plasminogen activator, urokinase. J Cell Biol. 1985;100:86-92.
12. Jackson CL, Raines E, Ross R, Reidy MA. Role of endogenous platelet-derived growth factor in arterial smooth muscle cell migration after balloon catheter injury. Arteriosclerosis. 1993;13: 1218-1226.
13. Lindner V, Reidy MA. Expression of basic fibroblast growth factor and its receptor by smooth muscle cells and endothelium in injured rat arteries: an en face study. Circ Res. 1993;73:589-595.
14. Wilcox JN, Smith KM, Williams LT, Schwartz SM, Gordon D. Platelet-derived growth factor mRNA detection in human atherosclerotic plaques by in situ hybridization. J Clin Invest. 1988;82: 1134-1143.
15. Schwartz SM, Benditt EP. Cell replication in the aortic endotnelium: a new method for study of the problem. Lab Invest. 1973;28: 699-707.
16. Zeheb R, Gelehrter TD. Cloning and sequencing of cDNA for rat plasminogen activator-1. Gene. 1988;73:459-468.
17. Rabbani SA, Rajwans N, Achbarou A, Murthy KK, Goltzman D. Isolation and characterization of multiple isoforms of the rat urokinase receptor in osteoblasts. FEBS Lett. 1994;338:69-74.
18. Clowes AW, Reidy MA, Clowes MM. Kinetics of cellular proliferation after arterial injury, I: smooth muscle growth in the absence of endothelium. Lab Invest. 1983;49:327-333.
19. Reidy MA, Clowes AW, Schwartz SM. Endothelial regeneration, V: inhibition of endothelial regrowth in arteries of rat and rabbit. Lab Invest. 1983;49:569-575.
20. Lane TF, Iruela-Arispe ML, Johnson RS, Sage EH. SPARC is a source of copper-binding peptides that stimulate angiogenesis. J Cell Biol. 1994;125:929-943.
21. Vassalli J-D, Wohlwend A, Belin D. Urokinase-catalyzed plasminogen activation at the monocyte/macrophage cell surface: a localized and regulated proteolytic system. Curr Top Microbiol Immunol. 1992;181:65-86.
22. Mignatti P, Mazzieri R, Rifkin DB. Expression of the urokinase receptor in vascular endothelial cells is stimulated by basic fibroblast growth factor. J Cell Biol. 1991;113:1193-1202.
23. Pollanen J, Hedman K, Nielsen LS, Dano K, Vaheri A. Ultrastructural localization of plasma membrane-associated urokinase-type plasminogen activator at focal contacts. J Cell Biol. 1988;106: 87-95.
24. Ragno P, Estreicher A, Gos A, Wohlwend A, Belin D, Vassalli J-D. Polarized secretion of urokinase-type plasminogen activator by epithelial cells. Exp Cell Res. 1992;203:236-243.
25. Stoppelli OD, Corti A, Soffientini G, Blasi F, Assoian RK. Differentiation-enhanced binding of the amino-terminal fragment of human plasminogen activator to a specific receptor on U937 monocytes. Proc Natl Acad Sci USA. 1985;82:4939-4943.
26. Montesano R, Pepper MS, Möhle-Steinlein U, Risau W, Wagner EF, Orci L. Increased proteolytic activity is responsible for the aberrant morphogenetic behavior of endothelial cells expressing the middle T oncogene. Cell. 1990;62:435-445.
27. Pepper MS, Belin D, Montesano R, Orci L, Vassalli J-D. Transforming growth factor-β1 modulates basic fibroblast growth factor-induced proteolytic and angiogenic properties of endothelial cells in vitro. J Cell Biol. 1990;111:743-755.
28. Pepper MS, Ferrara N, Orci L, Montesano R. Vascular endothelial growth factor (VEGF) induces plasminogen activators and plasminogen activator inhibitor-1 in microvascular endothelial cells. Biochem Biophys Res Commun. 1991;181:902-906.
29. Pepper MS, Montesano R. Proteolytic balance and capillary morphogenesis. Cell Differ Der. 1990;32:319-328.
30. Grainger DJ, Kemp PR, Liu AC, Lawn RM, Metcalf JC. Activation of transforming growth factor-beta in transgenic apolipoprotein(a) mice. Nature. 1994;370:460-462.
31. Grainger DJ, Kirschenlohr HL, Metcalf JC. Proliferation of human smooth muscle cells promoted by lipoprotein(a). Science. 1993;260: 1655-1658.
32. Majesky MW, Lindner V, Twardzik DR, Schwartz SW, Reidy MA. Production of transforming growth factor-β1 during repair of arterial injury. J Clin Invest. 1991;88:904-910.
33. Wolf YG, Rasmussen LM, Ruoslahti E. Antibodies against transforming growth factor-β1 suppress intimal hyperplasia in a rat model. J Clin Invest. 1994;93:1172-1178.
34. Fazioli F, Blasi F. Urokinase-type plasminogen activator and its receptor: new targets for anti-metastatic therapy? Trends Pharmacol Sci. 1994;15:25-29.
35. Stephens RW, Pollanen J, Tapiovaara H, Leung KC, Sim PS, Salonen EM, Ronne E, Behrendt N, Dano K, Vaheri A. Activation of pro-urokinase and plasminogen on human sarcoma cells: a proteolytic system with surface-bound reactants. J Cell Biol. 1989;108: 1987-1995.
36. Pyke C, Kristensen P, Ralfkiaer E, Grondahl-Hansen J, Eriksen J, Blasi F, Dano K. Urokinase-type plasminogen activator is expressed in stromal cells and its receptor in cancer cells at invasive foci in human colon adenocarcinomas. Am J Pathol. 1991;138: 1059-1067.
37. Noda-Heiny H, Daugherty A, Sobel BE. Augmented urokinase receptor expression in atheroma. Arterioscler Thromb Vasc Biol. 1995;15:37-43.
38. Jackson CL, Reidy MA. Basic fibroblast growth factor: its role in the control of smooth muscle cell migration. Am J Pathol. 1993;143: 1024-1031.
39. Lindner V, Reidy MA. Proliferation of smooth muscle cells after vascular injury is inhibited by an antibody against basic fibroblast growth factor. Proc Natl Acad Sci USA. 1991;88:3739-3743.
40. Majesky MW, Giachelli CM, Reidy MA, Schwartz SM. Rat carotid neointimal smooth muscle cells reexpress a developmentally regulated mRNA phenotype during repair of arterial injury. Circ Res. 1992;71:759-768.
41. Lindner V, Olson NE, Clowes AW, Reidy MA. Inhibition of smooth muscle cell proliferation in injured rat arteries: interaction of heparin with basic fibroblast growth factor. J Clin Invest. 1992;90: 2044-2049.
42. Olson NE, Chao S, Lindner V, Reidy MA. Intimal smooth muscle cell proliferation after balloon catheter injury: the role of basic fibroblast growth factor. Am J Pathol. 1992;140:1017-1023.
43. Hekman CM, Loskutoff DJ. Endothelial cells produce a latent inhibitor of plasminogen activators that can be denatured by denaturants. J Biol Chem. 1985;260:11581.
44. Schneiderman J, Sawdey MS, Keeton MR, Bordin GM, Bernstein EF, Dilley RB, Loskutoff DJ. Increased type 1 plasminogen activator inhibitor gene expression in atherosclerotic human arteries. Proc Natl Acad Sci USA. 1992;89:6998-7002.
45. Bachmann F, Kruithof E. Tissue plasminogen activator and physiological aspects. Semin Thromb Hemost. 1984;10:6-17.
46. Reidy MA. A reassessment of endothelial injury and arterial lesion formation. Lab Invest. 1985;53:513-520.
47. Reidy MA. Endothelial regeneration, VIII: interaction of smooth muscle cells with endothelial regrowth. Lab Invest. 1988;59:36-43.
48. Eldor A, Falcone DJ, Hajjar DP, Minick CR, Weksler BB. Recovery of prostacyclin production by de-endothelialized rabbit aorta: critical role of neointimal smooth muscle cells. J Clin Invest. 1981;67:735-741.
49. Hansson GK, Geng Y, Holm J, Hardhammar P, Wennmalm A, Jennische E. Arterial smooth muscle cells express nitric oxide synthase in response to endothelial injury. J Exp Med. 1994;180: 733-738.
50. Sawdey M, Poder TJ, Loskutoff DJ. Regulation of type 1 plasminogen inhibitor gene expression in cultured bovine aortic endothelial cells- induction by transforming growth factor-β, lipopolysaccharide and tumor necrosis factor. J Biol Chem. 1989;264:10396-10401.
51. Russell ME, Quertermous T, Declerck PJ, Collen D, Haber E, Homcy CJ. Binding of tissue-type plasminogen activator with human endothelial cell monolayers: characterization of the high affinity interaction with plasminogen activator inhibitor-1. J Biol Chem. 1990;265:2569-2575.