Phosphomonoester metabolism as a function of cell proliferative status and exogenous precursors

Anticancer Research

Volumn 16, Issue 3 B, 1996, Pages 1393-1397

  Aiken, Nanci R ^a   Gillies, Robert J ^a  

^a University of Arizona   (United States)

Author keywords

31P NMR spectroscopy; MRS; Nuclear magnetic resonance; Phospholipid metabolism; Phosphorylcholine; Phosphorylethanolamine; Proliferation

Indexed keywords

CHOLINE; PHOSPHOETHANOLAMINE; PHOSPHORYLCHOLINE;

ANIMAL CELL; CELL PROLIFERATION; CONFERENCE PAPER; CONTROLLED STUDY; HUMAN; HUMAN CELL; NONHUMAN; PHOSPHOLIPID METABOLISM; PRIORITY JOURNAL;

3T3 CELLS; ANIMALS; CELL DIVISION; CHO CELLS; CHOLINE; CRICETINAE; ETHANOLAMINES; HUMANS; MICE; PHOSPHORYLCHOLINE;

EID: 0030057174     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (19)

1. Mato JM: Phospholipid metabolism and turnover: phosphatidic acid, phosphatidylcholine and phosphatidylethanolamine. In: Phospholipid Metabolism in Cellular Signaling (J. M. Mato, Ed.). Boca Raton, CRC Press, 1990, pp. 61-79.
2. Negendank WG: Studies of human tumors by MRS: a review. NMR Biomed 5: 303-324, 1992.
3. Francis IR: Malignant hepatic tumors. Radiol. 180: 341-344, 1991.
4. 31P NMR spectra from human breast tumors. Variations in phospholipid metabolism. Brit J Cancer 63: 514-516, 1991.
5. Shinkwin MA: Integrated MRI and phosphorus spectroscopy of soft tissue tumors. Cancer 67: 1849-1858, 1991.
6. 31P MRS of human breast cancer in vivo. Proc. Am. Assoc. Cancer Res 32: 202a, 1991.
7. 18F deoxyglucose and image-guided 31p MRS in brain tumors. J. Nucl. Med. 31: 302-310, 1990.
8. 31P MRS in humans by spectroscopic imaging localized spectroscopy and metabolite imaging. Magn. Reson. Med. 12: 291-305, 1984.
9. Daly PF and Cohen JC: Magnetic resonance spectroscopy of tumors and potential in vivo clinical applications: a review. Cancer Res 49: 770-779, 1989.
10. Smith TAD: The effect of intra-tumor heterogeneity on the distribution of phosphorus-containing metabolites within human breast tumors. NMR Biomed 4: 262-267, 1991.
11. 31P NMR spectroscopic changes during liver regeneration. Int J Radiat Oncol Biol Phys 18: 1341-1350, 1990.
12. 31p NMR Spectroscopic changes during liver regeneration. J Surg Res 49: 244-247, 1990.
13. Gillies RJ, Galons JP, McGovern KA, Scherer PG, Lien YH, Job C, Ratcliff R, Chapa F, Cerdan S and Dale BE: Design and application of NMRcompatible bioreactor circuits for extended perfusion of high-density mammalian cell cultures. NMR Biomed 6: 95-104, 1993.
14. 31P nuclear magnetic resonance spectroscopic probe of intracellular volume in mammalian cell cultures. Biochem 32: 4665-4670, 1993.
15. 13C NMR studies of choline and ethanolamine uptake. Biochem. Biophys. Acta 1138: 203-212, 1992.
16. Freyer JP, Schor PL, Jarret KA, Neeman M and Sillerud LO: Cellular energetics measured by phosphorous nuclear magnetic resonance spectroscopy are not correlated with chronic nutrient deficiency in multicellular tumor spheroids. Cancer Res 51: 3831-3837, 1991.
17. Ronen SM, Steir A and Degani H: NMR studies of the lipid metabolism of T47D human breast cancer spheroids. FEBS Lett 266: 147-147, 1990.
18. Ronen S and Degani H: In Eleventh Annual Meeting of the Society of Magnetic Resonance in Medicine; Berlin, 1992.
19. Degan H, Horwitz A and Itzchak Y: Breast tumors: evaluation with P-31 MR spectroscopy. Radiol 161: 53-55, 1986.