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1
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0025012854
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L651582, a novel antiproliferative and antimetastasis agent
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E. C. Kohn and L. A. Liotta: L651582, a novel antiproliferative and antimetastasis agent. J. Natl. Cancer Inst. 82, 54-50 (1990).
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(1990)
J. Natl. Cancer Inst.
, vol.82
, pp. 54-150
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Kohn, E.C.1
Liotta, L.A.2
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2
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0026740712
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In vivo efficacy of a novel inhibitor of selected signal transduction pathways including calcium, arachidonate, and inositol phosphates
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E. C. Kohn, M. A. Sandeen, and L. A. Liotta: In vivo efficacy of a novel inhibitor of selected signal transduction pathways including calcium, arachidonate, and inositol phosphates. Cancer Res. 52, 3208-3212 (1992).
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(1992)
Cancer Res.
, vol.52
, pp. 3208-3212
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Kohn, E.C.1
Sandeen, M.A.2
Liotta, L.A.3
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3
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0028913347
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Angiogenesis: Role of calcium-mediated signal transduction
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E. C. Kohn, R. Alessandro, J. Spoonster, R. Wersto, and L. A. Liotta: Angiogenesis: role of calcium-mediated signal transduction. Proc. Natl. Acad. Sci. U.S.A. 92, 1307-1311 (1995).
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(1995)
Proc. Natl. Acad. Sci. U.S.A.
, vol.92
, pp. 1307-1311
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Kohn, E.C.1
Alessandro, R.2
Spoonster, J.3
Wersto, R.4
Liotta, L.A.5
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4
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0028040432
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Calcium influx modulates expression of matrix metalloproteinase-2 (72 kDa type IV collagenase, gelatinase A) expression
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E. C. Kohn, W. Jacobs, Y. S. Kim, R. Alessandro, W. G. Stetler-Stevenson, and L. A. Liotta: Calcium influx modulates expression of matrix metalloproteinase-2 (72 kDa type IV collagenase, gelatinase A) expression. J. Biol. Chem. 269, 21505-21511 (1994).
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(1994)
J. Biol. Chem.
, vol.269
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Kohn, E.C.1
Jacobs, W.2
Kim, Y.S.3
Alessandro, R.4
Stetler-Stevenson, W.G.5
Liotta, L.A.6
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5
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0025772585
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The antiproliferative and antimetastatic compound L651582 inhibits muscarinic acetylcholine receptor-stimulated calcium influx and arachidonic acid release
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C. C. Felder, A. L. Ma, L. A. Liotta, and E. C. Kohn: The antiproliferative and antimetastatic compound L651582 inhibits muscarinic acetylcholine receptor-stimulated calcium influx and arachidonic acid release. J. Pharmacol. Exp. Ther. 257, 967-971 (1991).
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(1991)
J. Pharmacol. Exp. Ther.
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Felder, C.C.1
Ma, A.L.2
Liotta, L.A.3
Kohn, E.C.4
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6
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0027503305
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Muscarinic receptor-mediated tyrosine phosphorylation of phospholipase C-gamma: Alternative mechanism for cholinergic receptor-induced phosphoinositide breakdown
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F. Gusovsky, J. E. Lueders, E. C. Kohn, and C. C. Felder: Muscarinic receptor-mediated tyrosine phosphorylation of phospholipase C-gamma: alternative mechanism for cholinergic receptor-induced phosphoinositide breakdown. J. Biol. Chem. 268, 7768-7772 (1993).
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(1993)
J. Biol. Chem.
, vol.268
, pp. 7768-7772
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Gusovsky, F.1
Lueders, J.E.2
Kohn, E.C.3
Felder, C.C.4
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7
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0028205812
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Structure function analysis of signal and growth inhibition by carboxyamido-triazole, CAI
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E. C. Kohn, C. C. Felder, W. Jacobs, K. A. Holmes, A. F. Day, R. Freer, and L. A. Liotta: Structure function analysis of signal and growth inhibition by carboxyamido-triazole, CAI. Cancer Res. 54, 935-942 (1994).
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(1994)
Cancer Res.
, vol.54
, pp. 935-942
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Kohn, E.C.1
Felder, C.C.2
Jacobs, W.3
Holmes, K.A.4
Day, A.F.5
Freer, R.6
Liotta, L.A.7
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8
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9044229717
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Clinical investigation of a cytostatic calcium influx inhibitor in patients with refractory cancers
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E. C. Kohn, E. Reed, E. Sarosy, M. Christian, C. J. Link, K. A. Cole, W. D. Figg, P. A. Davis, J. Jacob, B. Goldspiel, and L. A. Liotta: Clinical investigation of a cytostatic calcium influx inhibitor in patients with refractory cancers. Cancer Res. 56, 569-573 (1996).
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(1996)
Cancer Res.
, vol.56
, pp. 569-573
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Kohn, E.C.1
Reed, E.2
Sarosy, E.3
Christian, M.4
Link, C.J.5
Cole, K.A.6
Figg, W.D.7
Davis, P.A.8
Jacob, J.9
Goldspiel, B.10
Liotta, L.A.11
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9
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0029116458
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Pharmacokinetics of orally administered carboxyamido-triazole (CAI), an inhibitor of calcium-mediated signal transduction
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W. D. Figg, K. A. Cole, E. Reed, S. M. Steinberg, S. C. Piscitelli, P. A. Davis, M. J. Soltis, J. Jacob, S. Soudoulas, B. Goldspiel, G. Sarosy, L. A. Liotta, and E. C. Kohn: Pharmacokinetics of orally administered carboxyamido-triazole (CAI), an inhibitor of calcium-mediated signal transduction. Clin. Cancer Res. 1, 797-803 (1995).
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Clin. Cancer Res.
, vol.1
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Figg, W.D.1
Cole, K.A.2
Reed, E.3
Steinberg, S.M.4
Piscitelli, S.C.5
Davis, P.A.6
Soltis, M.J.7
Jacob, J.8
Soudoulas, S.9
Goldspiel, B.10
Sarosy, G.11
Liotta, L.A.12
Kohn, E.C.13
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10
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0027518744
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Quantitation of plasma levels of a novel anticancer drug, carboxyamidotriazole (CAI) by high pressure liquid chromatography
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K. A. Holmes, C. Chaffins, B. Osborne, L. A. Liotta, and E. C. Kohn: Quantitation of plasma levels of a novel anticancer drug, carboxyamidotriazole (CAI) by high pressure liquid chromatography. J. Chrom. Biomed. Appl. 613, 317-325 (1993).
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J. Chrom. Biomed. Appl.
, vol.613
, pp. 317-325
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Holmes, K.A.1
Chaffins, C.2
Osborne, B.3
Liotta, L.A.4
Kohn, E.C.5
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11
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0028945544
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Similarity of metabolism for CAI (NSC 609974) in human liver tissue in vitro and in humans in vivo
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L. K. Ludden, J. M. Strong, E. C. Kohn, and J. M. Collins: Similarity of metabolism for CAI (NSC 609974) in human liver tissue in vitro and in humans in vivo. Clin. Cancer Res. 1, 399-405 (1995).
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Clin. Cancer Res.
, vol.1
, pp. 399-405
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Ludden, L.K.1
Strong, J.M.2
Kohn, E.C.3
Collins, J.M.4
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12
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0025975978
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Isolation and characterization of a novel quaternary ammonium-liked glucuronide of lamotrigne
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M. W. Sinz and R. P. Remmel: Isolation and characterization of a novel quaternary ammonium-liked glucuronide of lamotrigne. Drug Metab. Dispos. 19, 149-153 (1991).
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Drug Metab. Dispos.
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Sinz, M.W.1
Remmel, R.P.2
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15
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0026750647
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The human hepatic cytochromes P450 involved in drug metabolism
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S. A. Wrighton and J. C. Stevens: The human hepatic cytochromes P450 involved in drug metabolism. Crit. Rev. Toxicol. 22, 1-21 (1992).
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Crit. Rev. Toxicol.
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Wrighton, S.A.1
Stevens, J.C.2
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16
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0026568284
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Glucuronidation of the dopamine D-1 receptor antagonists NNC 0756 and NNC 0772 in liver microsomes
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T. K. Hansen, K. F. Thomsen, and H. Bundagaard: Glucuronidation of the dopamine D-1 receptor antagonists NNC 0756 and NNC 0772 in liver microsomes. Drug Metab. Dispos. 20, 172-178 (1992).
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Drug Metab. Dispos.
, vol.20
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Hansen, T.K.1
Thomsen, K.F.2
Bundagaard, H.3
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