Activin and follistatin as local regulators in the human ovary

NeuroSignals

Volumn 5, Issue 2, 1996, Pages 81-89

  Peng, Chun ^a   Ohno, Tsukasa ^b   Khorasheh, Shideh ^b   Leung, Peter C K ^b  

^a YORK UNIVERSITY   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Activin; Activin receptors; Follistatin; Human; Ovary

Indexed keywords

ACTIVIN; CELL RECEPTOR; ESTRADIOL; FOLLISTATIN; MESSENGER RNA;

CELL PROLIFERATION; ESTROGEN SYNTHESIS; GRANULOSA CELL; HUMAN; HUMAN CELL; IMMUNOREACTIVITY; LUTEAL CELL; NONHUMAN; OVARY FOLLICLE; OVARY FUNCTION; OVULATION; RAT; REVIEW; STEROIDOGENESIS;

ACTIVIN RECEPTORS; ACTIVINS; FEMALE; FOLLISTATIN; GLYCOPROTEINS; GRANULOSA CELLS; GROWTH SUBSTANCES; HUMANS; INHIBINS; OVARY; RECEPTORS, GROWTH FACTOR; STEROIDS;

EID: 0030055967     PISSN: 1424862X     EISSN: 14248638     Source Type: Journal    
DOI: 10.1159/000109177     Document Type: Article

References (51)

1. Ying SY: Inhibins, activins, and follistatin: Gonadal proteins modulating the secretion of follicle-stimulating hormone. Endocr Rev 1988;9: 267-293.
2. Michel U, Famworth P, Findlay JK: Follistatin: More than follicle-stimulating hormone suppressing proteins. Mol Cell Endocrinol 1993;91: 1-11.
3. Findlay JK: Peripheral and local regulators of folliculogenesis. Re-prod Fertil Dev 1994;6:127-139.
4. Mathews LS: Activin receptors and cellular signaling by the receptor serine kinase family. Endocr Rev 1994; 15:310-325.
5. Eramaa M, Heikinheimo K, Tuuri T, Hildén K, Ritvos O: Inhibin/activin subunit mRNA expression in human granulosa-luteal cells. Mol Cell Endocrinol 1993;92:R15-R20.
6. Roberts VJ, Barth S, El-Rociy A, Yen SSC: Expression of inhibin/ac-tivin subunits and follistatin messenger ribonucleic acids and protein in ovarian follicles and the corpus luteum during the human menstrual cycle. J Clin Endocrinol Metab 1993;77:1402-1410.
7. Rabinovici J, Spencer SJ, Doldi N, Goldsmith PC, Schwall R, Jaffe RB: Activin-A as an intraovarian modulator: Actions, localization, and regulation of the intact dimer in human ovarian cells. J Clin Invest 1992;89: 1528-1536.
8. Rabinovici J, Spencer SJ, Jaffe RB: Recombinant human activin-A promotes proliferation of human luteinized preovulatory granulosa cells in vitro. J Clin Endocrinol Metab 1990;71:1396-1398.
9. Li W, Ho Yuen B, Leung PCK: Inhibition of progesterone accumulation by activin-A in human granulosa cells. J Clin Endocrinol Metab 1992; 75:285-289.
10. Peng C, Huang T-HJ, Jeung E-B, Donaldson CJ, Vale WW, Leung PCK: Expression of the type 11 ac-tivin receptor gene in the human placenta. Endocrinology 1993; 133: 3046-3049.
11. Eramaa M, Hilden K, Tuuri T, Rit-vos O: Regulation of inhibin/activin subunit messenger ribonucleic acids (mRNAs) by activin A and expression of activin receptor mRNAs in cultured human granulosa-luteal cells. Endocrinology 1995;136: 4382-4389.
12. Manson AJ, Niall HD, Seeburg PH: Structure of two human ovarian in-hibins. Biochem Biophys Res Com-mun 1986;135:957-964.
13. Roberts VJ, Barth S, El-Roeiy A, Yen SSC: Expression of inhibin/activin subunits and follistatin messenger ribonucleic acid and proteins in ovarian follicles from women with polycystic ovarian syndrome. J Clin Endocrinol Metab 1994;79: 1434-1439.
14. Schwall RH, Mason AJ, Wilcox JN, Bassett SG, Zeleznik AJ: Localization of inhibin/activin subunit mRNAs within the primate ovary. Mol Endocrinol 1990;4:75-79.
15. Eramaa M, Tuuri T, Hildin K, Ritvos O: Regulation of inhibin a and pA subunit messenger ribonucleic acid levels by chorionic gonadotropin and recombinant follicle-stimulating hormone in cultured human granulosa-luteal cells. J Clin Endocrinol Metab 1994;79:1670-1677.
16. Tisdall DJ, Hudson N, Smith P, McNatty KP: Localization of ovine follistatin and alpha and beta A inhibin mRNA in the sheep ovary during the oestrous cycle. J Mol Endocrinol 1994;12:181-193.
17. Hillier SG, Yong EL, Illingworth PJ, Baird DT, Schwall RH, Mason AJ: Effect of recombinant activin on androgen synthesis in cultured human thecal cells. J Clin Endocrinol 1991; 72:1206-1211.
18. Cataldo NA, Rabinovici J, Fujimoto VY, Jaffe RB: Follistatin antagonizes the effects of activin-A on steroidogenesis in human luteinizing granulosa cells. J Clin Endocrinol Metab 1994;79:272-277.
19. Li R, Phillips DM, Mather JP: Activin promotes ovarian follicle development in vitro. Endocrinology 1995;136:849-856.
20. Kaipia A, Toppari J, Huhtaniemi I, Paranko J: Sex difference in the action of activin-A on cell proliferation of differentiating rat gonad. Endocrinology 1994; 134:2165-2170.
21. Simone ND, Lanzone A, Petraglia F, Ronsisvalle E, Caruso A, Mancuso S: Effect of activin-A on progesterone synthesis in human luteal cells. Fértil Steril 1994:62:1157-1161.
22. Hillier SG, Yong EL, Illingworth PJ, Baird DT, Schwall RH, Mason AJ: Effect of recombinant inhibin on androgen synthesis in cultured human thecal cells. Mol Cell Endocrinol 1991;75:R1-R6.
23. l25I]inhibin-A to the adult rat ovary. Endocrinology 1993,133: 2998-3006.
24. Mathews LS, Vale WW: Expression cloning of an activin receptor, a predicted transmembrane serine kinase. Cell 1991;65:973-982.
25. Wrana JL, Attisano L, Wieser R, Ventura F, Massague J: Mechanism of activation of the TGF-ß receptor. Nature 1994;370:341-347.
26. Matsuzaki K, Xu J, Wang F, McKeehan WL, Krummen L, Kan M: A widely expressed transmcm-brane serine/threonine kinase that does not bind activin, inhibin, transforming growth factor p, or bone morphogenic factor. J Biol Chem 1993;268:12719-12723.
27. ten Dijke P, Ichijo H, Franzen P, Schulz P, Saras J, Toyoshima H, Heldin C-H, Miyazono K: Activin receptor-like kinases: A novel subclass of ccll-surface receptors with predicted serinc/thrconine activity. Oncogene 1993;8:2879-2887.
28. Donaldson CJ, Mathews LS, Vale W: Molecular cloning and binding properties of the human type II activin receptor. Biochem Biophys ResCommun 1992;184:310-316.
29. Hilden BK, Tuuri T, Eramaa M, Ritvos O: Expression of type 11 activin receptor genes during differentiation of human K562 cells and cDNA cloning of the human type 1IB activin receptor. Blood 1994;83: 2163-2170.
30. Cameron VA, Nishimura E, Mathews LS, Lewis KA, Sawchenko PE, Vale WW: Hybridization histo-chemical localization of activin receptor subtypes in rat brain, pituitary, ovary, and testis. Endocrinology 1994;134:799-808.
31. Feng Z-M, Madigan MB, Chen C-LC: Expression of type II activin receptor genes in the male and female reproductive tissues of the rat. Endocrinology 1993; 132:2593-2600.
32. He WW, Gustafson ML, Hirobe S, Donahoe PK: Developmental expression of four novel serine/threonine kinase receptors homologous to the activin/transforming growth fac-tor-p type II receptor family. Dev Dyn 1993;196:133-142.
33. Shinozaki H, Ito I, Hasegawa Y, Nakamura K, Igarashi S, Nakamura M, Miyamoto K, Eto Y, Ibuki Y, Mine-gishi T: Cloning and sequencing of a rat type II activin receptor. FEBS Lett 1992;312:53-56.
34. r 35000 monomeric protein that inhibits the release of follicle-stimulating hormone. Proc Natl Acad Sci USA 1981;84:8282-8286.
35. Nakamura T, Takio K, Eto Y, Shi-bai H, Titani K, Sugino H: Activin-binding protein from rat ovary is follistatin. Science 1990;247:836-838.
36. Shimonaka M, Inouyc S, Shimasaki S, Ling N: Follistatin binds to both activin and inhibin through the common beta-subunits. Endocrinology 1991;128:3313-3315.
37. Kogawa K, Nakamura T, Sugino K, Takio K, Titani K, Sugino H: Activ-in-binding protein is present in the pituitary. Endocrinology 1991;128: 1434-1440.
38. Shimasaki S, Koga M, Esch F, Cooksey K, Mercado M, Koba A, Ueno N, Ying S-Y, Ling N, Guillemin R: Primary structure of the human follistatin precursor and its genomic organization. Proc Natl Acad Sci USA 1988;85:4218-4222.
39. Schneyer AL, O’Neil DA, Crowley WF Jr. Activin-binding proteins in human serum and follicular fluid. J Clin Endocrinol Metab 1992;74: 1320-1324.
40. Sadatsuki M, Tsutsumi O, Sakai R, Eto Y, Hayashi N, Taketani Y: Presence and possible function of activ-in-like substance in human follicular fluid. Hum Rcprod 1993;8:1392-1395.
41. Krummen LA, Woodruff TK, De-Guzman G, Cox ET, Baly DL, Mann E, Garg S, Wong W-L, Cos-sum P, Mather JP: Identification and characterization of binding proteins for inhibin and activin in human serum and follicular fluids. Endocrinology 1993;132:431-443.
42. Tuuri T, Eramaa M, Hilden K, Ritvos O: Activin-binding protein follistatin messenger ribonucleic acid and secreted protein levels are induced by chorionic gonadotropin in cultured human granulosa-luteal cells. Endocrinology 1994; 135: 2196-2203.
43. Peng C, Leung PCK: Follistatin action and gene expression in human granulosa-luteal cells; in Fertility Regulation: Present and Future. Be-thesda, National Institutes of Health, in press.
44. Nakatani A, Shimasaki S, Depaolo LV, Erickson GF, Ling N: Cyclic changes in follistatin messenger ribonucleic acid and its protein in rat ovary during the estrous cycle. Endocrinology 1991;129:603-611.
45. Ogawa K, Kurohmaru M, Sugino H, Hayashi Y: Changes in the immuno-reactivity of follistatin within preovulatory follicles after the primary gonadotrophin surge in rats. J Re-prod Fertil 1994;101:577-581.
46. Shimasaki S, Koga M, Buscaglia ML, Simmons DM, Bicsak TA, Ling N: Follistatin gene expression in the ovary and extragonadal tissues. Mol Endocrinol 1989;3:651-659.
47. Shukovski L, Zheng ZW, Michel U, Findlay JK: FSH-suppressing protein (FSP) mRNA expression in bovine ovarian tissues. J Reprod Fertil 1992;95:861-867.
48. Lindsell CE, Misra V, Murphy BD: Regulation of follistatin messenger ribonucleic acid in porcine granulosa cells by epidermal growth factor and the protein kinase-C pathway. Endocrinology 1993; 132: 1630-1636.
49. Li W, Khorashch S, Ho Yuen B, Ling N, Leung PCK: Stimulation of progesterone secretion by recombinant follistatin-288 in human granulosa cells. Endocrinology 1993; 132: 1750-1756.
50. Xiao S, Findlay JK: Interactions between activin and FSH-suppressing protein and their mechanism of action on cultured rat granulosa cells. Mol Cell Endocrinol 1991;79:99-107.
51. Matzuk MM, Lu N, Vogel H, Sell-heycr K, Roon DR, Bradley A: Multiple defects and perinatal death in mice deficient in follistatin. Nature 1995;374:360-363.