Developmental expression of GABA transporters GAT1 and GAT4 suggests involvement in brain maturation

Journal of Neurochemistry

Volumn 67, Issue 2, 1996, Pages 857-867

  Jursky, Frantisek ^a   Nelson, Nathan ^b  

^a HOFFMANN LA ROCHE INC   (United States)

^b TEL AVIV UNIVERSITY   (Israel)

Author keywords

GABA transporter; GAT1; GAT4; Growth cones; Immunocytochemistry; Radial glia; Rat CNS development; Synaptogenesis

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID RECEPTOR; CARRIER PROTEIN; HYBRID PROTEIN; POLYCLONAL ANTIBODY; RECOMBINANT PROTEIN;

ANIMAL TISSUE; ARTICLE; BRAIN DEVELOPMENT; BRAIN MATURATION; CONTROLLED STUDY; FEMALE; GABAERGIC TRANSMISSION; IMMUNOREACTIVITY; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALIA;

EID: 0030055881     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1996.67020857.x     Document Type: Article

References (42)

1. Altman J. and Bayer S. A. (1984) The development of the rat spinal cord. Adv. Anat. Embryol. Cell Biol. 85, 1-64.
2. Amara S. G. and Arriza J. L. (1993) Neurotransmitter transporters: three distinct gene families. Curr. Opin. Neurobiol. 3, 337-344.
3. Bennett M. K., Calakos N., Kreiner T., and Scheller R. H. (1992) Synaptic vesicle membrane proteins interact to form a multimeric complex. J. Cell Biol. 116, 761-775.
4. Borowsky B., Mezey E., and Hoffman B. J. (1993) Two glycine transporter variants with distinct localization in the CNS and peripheral tissues are encoded by a common gene. Neuron 10, 851-863.
5. Cherubini E., Gaiarsa J. L., and Ben-Ari Y. (1991) GABA: an excitatory transmitter in early postnatal life. Trends Neurosci. 14, 515-519.
6. Chun J. J. M. and Shatz C. J. (1989) The earliest-generated neurons of the cat cerebral cortex: characterization by MAP2 and neurotransmitter immunohistochemistry during the fetal life. J. Neurosci. 9, 1648-1667.
7. Clark J. A., Deutch A. Y., Gallipoli P. Z., and Amara S. G. (1992) Functional expression and CNS distribution of a β-alanine-sensitive neuronal GABA transporter. Neuron 9, 337-347.
8. A receptor. Neuroscience 40, 375-397.
9. Emerit M. B., Riad M., and Hamon M. (1992) Trophic effects of neurotransmitters during brain maturation. Biol. Neonate 62, 193-201.
10. Friszman M. L., Behar T., Lange G. D., Smith S. V., Novotny E. A., and Baker J. L. (1993) GABAergic cells and signals appear together in the early postmitotic period of telencephalic and striatal development. Dev. Brain Res. 73, 243-251.
11. A-receptor subtypes during postnatal development: an immunohistochemical study. J. Neurosci. 14, 5302-5324.
12. Gottesfeld Z. and Elliott K. A. (1971) Factors that affect the binding and uptake of GABA by brain tissue. J. Neurochem. 18, 683-690.
13. Guastella J., Nelson N., Nelson H., Czyzyk L., Keynan S., Miedel M. C., Davidson N., Lester H. A., and Kanner B. I. (1990) Cloning and expression of a rat brain GABA transporter. Science 249, 1303-1306.
14. Imamoto K., Karasawa N., Isomura G., and Nagatsu I. (1994) Cajal-Retzius neurons identified by GABA immunohistochemistry in layer I of the rat cerebral cortex. Neurosci. Res. 20, 101-105.
15. Iversen L. L. (1971) Role of transmitter uptake mechanism in synaptic neurotransmission. Br. J. Pharmacol 41, 571-591.
16. Iversen L. L. and Johnston G. A. R. (1971) GABA uptake in rat central nervous system: comparison of uptake in slices and homogenates and the effects of some inhibitors. J. Neurosci. 18, 1939-1950.
17. Iversen L. L. and Kelly J. S. (1975) Uptake and metabolism of γ-aminobutyric acid by neurones and glial cells. Biochem. Pharmacol. 24, 933-938.
18. Jursky F. and Nelson N. (1995) Localization of glycine neurotransmitter transporter (GLYT2) reveals correlation with the distribution of glycine receptor. J. Neurochem. 64, 1026-1033.
19. Jursky F., Tamura S., Tamura A., Madiyan S., Nelson H., and Nelson N. (1994) Structure, function and brain localization of neurotransmitter transporters. J. Exp. Biol. 196, 283-295.
20. Lauder J. M., Han V. K. M., Henderson P., Verdoorn T., and Towle A. C. (1986) Prenatal ontogeny of the GABAergic system in the rat brain: an immunocytochemical study. Neuroscience 19, 465-493.
21. Liu Q.-R., Lopez-Corcuera B., Madiyan S., Nelson H., and Nelson N. (1993a) Cloning and expression of a spinal cord- and brain-specific glycine transporter with novel structural features. J. Biol. Chem. 267, 17491-17493.
22. Liu Q.-R., Lopez-Corcuera B., Madiyan S., Nelson H., and Nelson N. (1993b) Molecular characterization of four pharmacologically distinct γ-aminobutyric acid transporters in mouse brain. J. Biol. Chem. 268, 2106-2112.
23. Ma W., Behar T., and Baker J. L. (1992) Transient expression of GABA immunoreactivity in the developing rat spinal cord. J. Comp. Neurol. 235, 271-290.
24. Mabjeesh N. J., Frese M., Rauen T., Jeserich G., and Kanner B. I. (1992) Neuronal and glial γ-aminobutyric acid transporters are distinct proteins. FEBS Lett. 299, 99-102.
25. Meier E., Hertz L., and Schousboe A. (1991) Neurotransmitters as developmental signals. Neurochem. Int. 19, 1-15.
26. Misson J.-P., Edwards M. A., Yamamoto M., and Caviness V. S. Jr. (1988) Identification of radial glial cells within the developing murine central nervous system: studies based upon a new immunohistochemical marker. Dev. Brain Res. 44, 95-108.
27. Nelson N. (1983) Structure and synthesis of chloroplast ATPase. Methods Enzymol. 97, 510-513.
28. Nelson N. and Lill H. (1993) Poters and neurotransmitters. J. Exp. Biol. 196, 213-228.
29. Nelson H., Mandiyan S., and Nelson N. (1990) Cloning of the human brain GABA transporter. FEBS Lett. 269, 181-184.
30. Ochi S., Lim J. Y., Rand M. N., During M. J., Sakatani K., and Kocsis J. D. (1993) Transient presence of GABA in astrocytes of the developing optic nerve. Glia 9, 188-198.
31. Oudega M., Lakke E. A. J. F., Marani E., and Thomeer R. T. W. M. (1993) Development of the spinal cord: immuno- and enzyme histochemical approaches. Adv. Anat. Embryol. Cell Biol. 129, 1-166.
32. Pietrini G., Suh Y. J., Edelmann L., Rudnick G., and Caplan M. J. (1994) The axonal γ-aminobutyric acid transporter GAT-1 is sorted to the apical membranes of polarized epithelial cells. J. Biol. Chem. 269, 4668-4674.
33. Radian R., Ottersen O. P., Mathisen-Storm J., Castel M., and Kanner B. I. (1990) Immunocytochemical localization of the GABA transporter in rat brain. J. Neurosci. 10, 1319-1330.
34. Raiteri M., Bonanno G., and Pende M. (1992) γ-Aminobutyric acid and glycine modulate each other's release through heterocarriers sited on the releasing axon terminals of rat CNS. J. Neurochem. 59, 1481-1489.
35. Rakic P. (1974) Neurons in the rhesus monkey visual cortex: systematic relationship between time of origin and eventual disposition. Science 183, 425-427.
36. Rothstein J. D., Martin L., Levey A. I., Dykes-Hoberg M., Jin L., Wu D., Nash N., and Kuncl R. W. (1994) Localization of neuronal and glial glutamate transporters. Neuron 13, 713-725.
37. Saito N., Ikegaki N., Sakai N., and Honda S. (1994) Distinct localization of GABA transporter subtypes and their functional modulation by PKC. Soc. Neurosci. Abstr. 20, 919.
38. Schousboe A., Hertz L., and Svenneby G. (1977) Uptake and metabolism of GABA in astrocytes cultured from dissociated mouse brain cultures. Neurochem. Res. 2, 217-229.
39. Swanson T. G., Umbach J. A., and Gundersen C. B. (1994) Glia of the cholinergic electromotor nucleus of Torpedo are the source of the cDNA enconding a GAT-1-like GABA transporter. J. Neurochem. 63, 1-12.
40. Taylor J. and Gordon-Weeks P. R. (1989) Developmental changes in the calcium dependency of γ-aminobutyric acid release from isolated growth cones: correlation with growth cone morphology. J. Neurochem. 53, 834-843.
41. Taylor J., Docherty M., and Gordon-Weeks P. R. (1990) GABAergic growth cones: release of endogenous γ-aminobutync acid precedes the expression of synaptic vesicle antigens. J. Neurochem. 54, 1689-1699.
42. 3H]GABA. Dev. Brain Res. 10, 265-277.