메뉴 건너뛰기




Volumn 5, Issue 2, 1996, Pages 91-95

Reversal of tumour drug resistance with monoclonal antibodies prospects and problems

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; GLYCOPROTEIN P; MONOCLONAL ANTIBODY;

EID: 0030055841     PISSN: 11727039     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF03259316     Document Type: Article
Times cited : (1)

References (36)
  • 1
    • 0024329881 scopus 로고
    • The biochemistry of P-glycoprotein-mediated multidrug resistance
    • Endicott JA, Ling V. The biochemistry of P-glycoprotein-mediated multidrug resistance. Annu Rev Biochem 1989; 58: 137-71
    • (1989) Annu Rev Biochem , vol.58 , pp. 137-171
    • Endicott, J.A.1    Ling, V.2
  • 2
    • 0027218689 scopus 로고
    • Biochemistry of multidrug resistance mediated by the multidrug transporter
    • Gottesman MM, Pastan I. Biochemistry of multidrug resistance mediated by the multidrug transporter. Annu Rev Biochem 1993:62:385-427
    • (1993) Annu Rev Biochem , vol.62 , pp. 385-427
    • Gottesman, M.M.1    Pastan, I.2
  • 3
    • 0023888724 scopus 로고
    • Mechanism of multidrug resistance and implications for therapy
    • Tsuruo T. Mechanism of multidrug resistance and implications for therapy. Jpn J Cancer Res 1988; 79: 285-96
    • (1988) Jpn J Cancer Res , vol.79 , pp. 285-296
    • Tsuruo, T.1
  • 4
    • 0003056126 scopus 로고
    • Reversal of multidrug resistance by calcium channel blokers and other agents
    • Roninson IB, editor. New York: Plenum Publishing Co.
    • Tsuruo T. Reversal of multidrug resistance by calcium channel blokers and other agents. In: Roninson IB, editor. Molecular and cellular biology of multidrug resistance in tumor cells. New York: Plenum Publishing Co., 1991: 349-72
    • (1991) Molecular and Cellular Biology of Multidrug Resistance in Tumor Cells , pp. 349-372
    • Tsuruo, T.1
  • 5
    • 0024506222 scopus 로고
    • Drug-resistance in multiple myeloma and non-Hodgkin's lymphoma: Detection of P-glycoprotein and potential circumvention by addition of verapamil to chemotherapy
    • Dalton WS, Grogan TM, Meltzer PS, et al. Drug-resistance in multiple myeloma and non-Hodgkin's lymphoma: detection of P-glycoprotein and potential circumvention by addition of verapamil to chemotherapy. J Clin Oncol 1989; 7: 415-24
    • (1989) J Clin Oncol , vol.7 , pp. 415-424
    • Dalton, W.S.1    Grogan, T.M.2    Meltzer, P.S.3
  • 6
    • 0026051296 scopus 로고
    • P-glycoprotein expression in malignant lymphoma and reversal of clinical drug resistance with chemotherapy plus high-dose verapamil
    • Miller TP, Grogan TM, Dalton WS,et al. P-glycoprotein expression in malignant lymphoma and reversal of clinical drug resistance with chemotherapy plus high-dose verapamil. J Clin Oncol 1991; 9: 17-24
    • (1991) J Clin Oncol , vol.9 , pp. 17-24
    • Miller, T.P.1    Grogan, T.M.2    Dalton, W.S.3
  • 7
    • 0026634681 scopus 로고
    • Modulation of multidrug-resistant multiple myeloma by cyclosporin
    • Sonneveld P, Durie BGM, Lokhorst HM, et al. Modulation of multidrug-resistant multiple myeloma by cyclosporin. Lancet 1992:340:255-9
    • (1992) Lancet , vol.340 , pp. 255-259
    • Sonneveld, P.1    Durie, B.G.M.2    Lokhorst, H.M.3
  • 9
    • 0023819244 scopus 로고
    • Monoclonal antibody JSB-I detects a highly conserved epitope on the P-glycoprotein associated with multidrug resistance
    • Scheper RJ, Bulte JWM, Brakkee JG, et al. Monoclonal antibody JSB-I detects a highly conserved epitope on the P-glycoprotein associated with multidrug resistance. Int J Cancer 1988:42:389-94
    • (1988) Int J Cancer , vol.42 , pp. 389-394
    • Scheper, R.J.1    Bulte, J.W.M.2    Brakkee, J.G.3
  • 10
    • 0345139075 scopus 로고
    • Functional role for the 170- To 180-kDa glycoprotein specific to drug-resistant tumor cells as revealed by monoclonal antibodies
    • Hamada H, Tsuruo T. Functional role for the 170- to 180-kDa glycoprotein specific to drug-resistant tumor cells as revealed by monoclonal antibodies. Proc Natl Acad Sei USA I986; 83: 7785-9
    • (1986) Proc Natl Acad Sei USA , vol.83 , pp. 7785-7789
    • Hamada, H.1    Tsuruo, T.2
  • 11
    • 0024412201 scopus 로고
    • Characterization of monoclonal antibodies recognizing an Mr 180,000 P-glycoprotein in muitidrug-resistant human tumor cells
    • Meyers MB. Rittman-Graner L, O'Brien JP, et al. Characterization of monoclonal antibodies recognizing an Mr 180,000 P-glycoprotein in muitidrug-resistant human tumor cells. Cancer Res 1989; 49: 3209-14
    • (1989) Cancer Res , vol.49 , pp. 3209-3214
    • Meyers, M.B.1    Rittman-Graner, L.2    O'Brien, J.P.3
  • 12
    • 0026711242 scopus 로고
    • Efficient inhibition of P-glycoprotein mediated multidrug resistance with a monoclonal antibody
    • Merchetner EB. Roninson IB. Efficient inhibition of P-glycoprotein mediated multidrug resistance with a monoclonal antibody. Proc Natl Acad Sei USA 1992; 89: 5824-8
    • (1992) Proc Natl Acad Sei USA , vol.89 , pp. 5824-5828
    • Merchetner, E.B.1    Roninson, I.B.2
  • 13
    • 0027459278 scopus 로고
    • Monoclonal antibody to an external epitope of the human mdr\ P-glycoprotein
    • Arceci RJ, Stieglitz K, Brass J, et al. Monoclonal antibody to an external epitope of the human mdr\ P-glycoprotein. Cancer Res 1993; 53: 310-7
    • (1993) Cancer Res , vol.53 , pp. 310-317
    • Arceci, R.J.1    Stieglitz, K.2    Brass, J.3
  • 14
    • 0027454141 scopus 로고
    • Binding properties of monoclonal antibodies recognizing external epitopes of the human MDR1 P-glycoprotein
    • Schinkel AH, Arceci RJ, Smit JJM, et al. Binding properties of monoclonal antibodies recognizing external epitopes of the human MDR1 P-glycoprotein. Int J Cancer 1993; 55: 478-84
    • (1993) Int J Cancer , vol.55 , pp. 478-484
    • Schinkel, A.H.1    Arceci, R.J.2    Smit, J.J.M.3
  • 15
    • 0025893144 scopus 로고
    • A combined approach for purging muitidrug-resistant leukemic cell lines in bone marrow using a monoclonal antibody and chemotherapy
    • Aihara M, Aihara Y, Schmidt-Wolf G, et al. A combined approach for purging muitidrug-resistant leukemic cell lines in bone marrow using a monoclonal antibody and chemotherapy. Blood 1991; 77: 2079-84
    • (1991) Blood , vol.77 , pp. 2079-2084
    • Aihara, M.1    Aihara, Y.2    Schmidt-Wolf, G.3
  • 16
    • 0026033940 scopus 로고
    • Characterization by somatic cell genetics of a monoclonal antibody to the MDR1 gene product (P-glycoprotein): Determination of P-glycoprolein expression in multi-drug-resistant KB and CEM cell variants
    • Cenciarelli C, Currier SJ, Willingham MC, et al. Characterization by somatic cell genetics of a monoclonal antibody to the MDR1 gene product (P-glycoprotein): determination of P-glycoprolein expression in multi-drug-resistant KB and CEM cell variants. Int J Cancer 1991; 47: 533-43
    • (1991) Int J Cancer , vol.47 , pp. 533-543
    • Cenciarelli, C.1    Currier, S.J.2    Willingham, M.C.3
  • 17
    • 0024814693 scopus 로고
    • Inhibition of muitidrugresistant human tumor growth in athymic mice by anti-Pglycoprotein monoclonal antibodies
    • Tsuruo T, Hamada H, Sato S, et al. Inhibition of muitidrugresistant human tumor growth in athymic mice by anti-Pglycoprotein monoclonal antibodies. Jpn J Cancer Res 1989: 80:627-31
    • (1989) Jpn J Cancer Res , vol.80 , pp. 627-631
    • Tsuruo, T.1    Hamada, H.2    Sato, S.3
  • 18
    • 0025224853 scopus 로고
    • Monoclonal anti-Pglycoprotein antibody-dependent killing of muitidrug-resistant tumor cells by human mononuclear cells
    • Heike Y, Hamada H, Inamura N, et al. Monoclonal anti-Pglycoprotein antibody-dependent killing of muitidrug-resistant tumor cells by human mononuclear cells. Jpn J Cancer Res 1990:81: 1155-61
    • (1990) Jpn J Cancer Res , vol.81 , pp. 1155-1161
    • Heike, Y.1    Hamada, H.2    Inamura, N.3
  • 19
    • 0027380596 scopus 로고
    • Specific targeting and killing activities of anti-P-glycoprotein monoclonal antibody MRK-16 directed against intrinsically muitidrug-resistant human colorectal carcinoma cell lines in nude mouse model
    • Iwahashi T, Okochi E, Ariyoshi K, et al. Specific targeting and killing activities of anti-P-glycoprotein monoclonal antibody MRK-16 directed against intrinsically muitidrug-resistant human colorectal carcinoma cell lines in nude mouse model. Cancer Res 1993; 53: 5475-82
    • (1993) Cancer Res , vol.53 , pp. 5475-5482
    • Iwahashi, T.1    Okochi, E.2    Ariyoshi, K.3
  • 20
    • 0027406201 scopus 로고
    • Enhancement of cellular accumulation of cyclosporin a by anti-P-glycoprotein monoclonal antibody MRK-16 and synergistic modulation of multidrug resistance
    • Naito M, Tsuge H, Kuroko C, et al. Enhancement of cellular accumulation of cyclosporin A by anti-P-glycoprotein monoclonal antibody MRK-16 and synergistic modulation of multidrug resistance. J Natl Cancer Inst 1993; 85: 311-6
    • (1993) J Natl Cancer Inst , vol.85 , pp. 311-316
    • Naito, M.1    Tsuge, H.2    Kuroko, C.3
  • 21
    • 0027167572 scopus 로고
    • Enhancement of reversing effect of cyclosporin Aon vincristine resistance by anti-P-glycoprotein monoclonal antibody MRK-16
    • Naito M. Tsuge H, Kuroko C, et al. Enhancement of reversing effect of cyclosporin Aon vincristine resistance by anti-P-glycoprotein monoclonal antibody MRK-16. Jpn J Cancer Res 1993; 84: 489-92
    • (1993) Jpn J Cancer Res , vol.84 , pp. 489-492
    • Naito, M.1    Tsuge, H.2    Kuroko, C.3
  • 22
    • 0023897361 scopus 로고
    • Increase of daunorubicin and vincristine accumulation in multidrug resistant human ovarian carcinoma cells by a monoclonal antibody reacting with P-glycoprotein
    • Broxterman HJ, Kuiper CM, Schuurhuis GJ, et al. Increase of daunorubicin and vincristine accumulation in multidrug resistant human ovarian carcinoma cells by a monoclonal antibody reacting with P-glycoprotein. Biochem Pharmacol 1988; 37: 2389-93
    • (1988) Biochem Pharmacol , vol.37 , pp. 2389-2393
    • Broxterman, H.J.1    Kuiper, C.M.2    Schuurhuis, G.J.3
  • 23
    • 0026094238 scopus 로고
    • Reversal of drug resistance in a human colon cancer xenograft expressing MDRI complementary DNA by in vivo administration of MRK 16 monoclonal antibody
    • Pearson JW, Fogler WE, Volker K, et al. Reversal of drug resistance in a human colon cancer xenograft expressing MDRI complementary DNA by in vivo administration of MRK 16 monoclonal antibody. J Natl Cancer Inst 1991; 83: 1386-91
    • (1991) J Natl Cancer Inst , vol.83 , pp. 1386-1391
    • Pearson, J.W.1    Fogler, W.E.2    Volker, K.3
  • 24
    • 0026692775 scopus 로고
    • Reversal of vinca alkaloid resistance by anti-P-glycoprotein monoclonal antibody HYB-241 in a human tumor xenograft
    • Rittmann-Grauer LS, Yong MA, Sanders V, et al. Reversal of vinca alkaloid resistance by anti-P-glycoprotein monoclonal antibody HYB-241 in a human tumor xenograft. Cancer Res 1992:52: 1810-6
    • (1992) Cancer Res , vol.52 , pp. 1810-1816
    • Rittmann-Grauer, L.S.1    Yong, M.A.2    Sanders, V.3
  • 25
    • 0024460574 scopus 로고
    • Elimination of drug resistant myeloma tumor cells lines by monoclonal anti-P-glycoprotcin antibody and rabbit complement
    • Kulkarni SS, Wang Z, Spitzer G, et al. Elimination of drug resistant myeloma tumor cells lines by monoclonal anti-P-glycoprotcin antibody and rabbit complement. Blood 1989: 74: 2244-51
    • (1989) Blood , vol.74 , pp. 2244-2251
    • Kulkarni, S.S.1    Wang, Z.2    Spitzer, G.3
  • 26
    • 0010244880 scopus 로고
    • A monoclonal antibody-P.vcME/omrwtt.s toxin conjugate that specifically kills multidrug-resistant cells
    • FitzGeruld DJ, Willingham MC, Cardarelli CO. et al. A monoclonal antibody-P.vcME/omrwtt.s toxin conjugate that specifically kills multidrug-resistant cells. Proc Natl Acad Sei USA 1987: H4: 4288-92
    • (1987) Proc Natl Acad Sei USA , vol.H4 , pp. 4288-4292
    • FitzGeruld, D.J.1    Willingham, M.C.2    Cardarelli, C.O.3
  • 27
    • 0025330368 scopus 로고
    • In vitrn bone marrow purging ot multidrug-resistant cells with a mouse monoclonal antibody directed against Mr 170,000 glycoprotein and a saporin-conjugated anti-mouse antibody
    • Dinota A, Tazzari PL. Michieli M, et al. In vitrn bone marrow purging ot multidrug-resistant cells with a mouse monoclonal antibody directed against Mr 170,000 glycoprotein and a saporin-conjugated anti-mouse antibody. Cancer Res 1990; 50:4291-4
    • (1990) Cancer Res , vol.50 , pp. 4291-4294
    • Dinota, A.1    Tazzari, P.L.2    Michieli, M.3
  • 28
    • 0025878672 scopus 로고
    • Magnetic-affinity cell sorting of human multidrug-resistant cells
    • Padmanabhan R. Tsuruo T. Kane SE. et al. Magnetic-affinity cell sorting of human multidrug-resistant cells. J Natl Cancer Inst 1991:83: 565-9
    • (1991) J Natl Cancer Inst , vol.83 , pp. 565-569
    • Padmanabhan, R.1    Tsuruo, T.2    Kane, S.E.3
  • 29
    • 0023447098 scopus 로고
    • Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues
    • Thiebaut F, Tsuruo T. Hamada H. et al. Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues. Proc Natl Acad Sei USA 1987: 84: 7735-8
    • (1987) Proc Natl Acad Sei USA , vol.84 , pp. 7735-7738
    • Thiebaut, F.1    Tsuruo, T.2    Hamada, H.3
  • 30
    • 0000712439 scopus 로고
    • Multidrug resis tance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites
    • Cordon-Cardo C. O'Brien JP, Casals D, et al. Multidrug resis tance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites. Proc Natl Acad Sei USA 1989: 86: 695-8
    • (1989) Proc Natl Acad Sei USA , vol.86 , pp. 695-698
    • Cordon-Cardo, C.1    O'Brien, J.P.2    Casals, D.3
  • 31
    • 0025799513 scopus 로고
    • Expression and activity of P-glycoprotein, a multidrug efflux pump, in human hematopoietic stem cells
    • Chaudhary PM, Roninson IB. Expression and activity of P-glycoprotein, a multidrug efflux pump, in human hematopoietic stem cells. Cell 1991; 66: 85-94
    • (1991) Cell , vol.66 , pp. 85-94
    • Chaudhary, P.M.1    Roninson, I.B.2
  • 32
    • 0026669192 scopus 로고
    • Functional itivuh einem of P-glycoprotein in blood-brain barrier
    • Talsula T. Naito M, Oh-hara T, cl al. Functional itivuh einem of P-glycoprotein in blood-brain barrier. J Biol Cheni 1992: 267: 20383-91
    • (1992) J Biol Cheni , vol.267 , pp. 20383-20391
    • Talsula, T.1    Naito, M.2    Oh-hara, T.3
  • 33
    • 0027956555 scopus 로고
    • Transport of cyclosporin a across the brain capillary endotheliai cell rnonolayer by Pglycoprotein
    • Shirai A. Naito M. Tatsuta T, et al. Transport of cyclosporin A across the brain capillary endotheliai cell rnonolayer by Pglycoprotein. Biochim Biophys Acta 1994; 1222: 400-4
    • (1994) Biochim Biophys Acta , vol.1222 , pp. 400-404
    • Shirai, A.1    Naito, M.2    Tatsuta, T.3
  • 34
    • 0028229150 scopus 로고
    • Disruption of the mouse nidi'Iu P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs
    • Schinkel AH. Smit JJ. van Tellingen O, et al. Disruption of the mouse nidi'Iu P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs. Cell 1994:77:491-502
    • (1994) Cell , vol.77 , pp. 491-502
    • Schinkel, A.H.1    Smit, J.J.2    Van Tellingen, O.3
  • 35
    • 0025362960 scopus 로고
    • Mouse-human chimeric antibody against the multidrug transporter P-glycoprotein
    • Hainada H. Miura K. Ariyoshi K. et al. Mouse-human chimeric antibody against the multidrug transporter P-glycoprotein. Cancer Res 1990: 50: 3167-71
    • (1990) Cancer Res , vol.50 , pp. 3167-3171
    • Hainada, H.1    Miura, K.2    Ariyoshi, K.3
  • 36
    • 0026571879 scopus 로고
    • Mouse-human chimeric antibody MHI71 against the multidrug transporter P-glycoprotein
    • Ariyoshi K. Hamada H. Naito M. et al. Mouse-human chimeric antibody MHI71 against the multidrug transporter P-glycoprotein. Jpn J Cancer Res 1992:X3: 515-21
    • (1992) Jpn J Cancer Res , vol.X3 , pp. 515-521
    • Ariyoshi, K.1    Hamada, H.2    Naito, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.