A short chemoenzymatic synthesis of (+)-Multifidene and (+)-Viridiene

Tetrahedron Letters

Volumn 37, Issue 7, 1996, Pages 1011-1014

  Lebreton, Jacques ^a   Alphand, Véronique ^a   Furstoss, Roland ^a  

^a AIX MARSEILLE UNIVERSITY   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOPENTANE DERIVATIVE; MULTIFIDEN; PHEROMONE; UNCLASSIFIED DRUG; VIRIDICINE;

ARTICLE; CHIRALITY; DRUG PURITY; DRUG SYNTHESIS; NUCLEAR MAGNETIC RESONANCE; REACTION ANALYSIS; STEREOCHEMISTRY;

EID: 0030055804     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/0040-4039(95)02363-1     Document Type: Article

References (35)

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27. 3) spectrum of the crude mixture are in agreement with the previous data reported in the literature (see ref. 6h) for the C-4 epimer of Multifidene 1.
28. Meyer S. D., Schreiber S. L. J. Org. Chem., 1994, 59, 7549-7552.
29. R = 27.9 min..
30. Boland W., Mertes K., Jaenicke L., Müller D. G., Fölster E. Helv. Chim. Acta., 1983, 66, 1905-1913.
31. The addition of a triphenyl(propenylidene)phosphorane solution to the reaction mixture at -78°C gave rise to a nearly 1/1 mixture of (+)-Viridiene 2 (Z isomer) and of its E isomer in low yield.
32. R = 26.0 min..
33. Cookson R.C., Gilani S.S.H., Stevens I.D.R. J.Chem. Soc.(C) 1967, 1906-1909.
34. 3) δ (ppm) : 37.1 (t), 47.2 (d), 51.7 (d), 114.3 (t), 115.2 (t), 130.7 (d), 130.9 (d), 133.1 (d), 134.6 (d), 137.0 (d), 139.9 (d).
35. R = 38.2 min..