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Volumn 107, Issue 2, 1996, Pages 188-194

Thapsigargin induces rapid, transient growth inhibition and c-fos expression followed by sustained growth stimulation in mouse keratinocyte cultures

Author keywords

Hyperplasia; Protein synthesis; Tumor promotion

Indexed keywords

3 [1 (3 AMINOPROPYL) 3 INDOLYL] 4 (1 METHYL 3 INDOLYL) 1H PYRROLE 2,5 DIONE; THAPSIGARGIN;

EID: 0030055780     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1111/1523-1747.ep12329592     Document Type: Article
Times cited : (14)

References (49)
  • 1
    • 0021833818 scopus 로고
    • The ability of thapsigargin and thapsigargicin to activate cells involved in the inflammatory response
    • Ali H, Christensen SB, Foreman JC, Pearce FL, Piotrowski W, Thastrup O: The ability of thapsigargin and thapsigargicin to activate cells involved in the inflammatory response. Br J Pharmacol 85:705-712, 1985
    • (1985) Br J Pharmacol , vol.85 , pp. 705-712
    • Ali, H.1    Christensen, S.B.2    Foreman, J.C.3    Pearce, F.L.4    Piotrowski, W.5    Thastrup, O.6
  • 2
    • 0019787422 scopus 로고
    • Promotion of carcinomas by repeated abrasion in initiated skin of mice
    • Argyris TS, Slaga TJ: Promotion of carcinomas by repeated abrasion in initiated skin of mice. Cancer Res 41:5193-5195, 1981
    • (1981) Cancer Res , vol.41 , pp. 5193-5195
    • Argyris, T.S.1    Slaga, T.J.2
  • 3
    • 0027483340 scopus 로고
    • Effects of the selective protein kinase C inhibitor, Ro 31-7549, on the proliferation of cultured mouse epidermal keratinocytes
    • Bollag WB, Ducote J, Harmon CS: Effects of the selective protein kinase C inhibitor, Ro 31-7549, on the proliferation of cultured mouse epidermal keratinocytes. J Invest Dermatol 100:240-246, 1993
    • (1993) J Invest Dermatol , vol.100 , pp. 240-246
    • Bollag, W.B.1    Ducote, J.2    Harmon, C.S.3
  • 4
    • 0028260490 scopus 로고
    • Regulation of fos-lacZ fusion gene expression in primary mouse epidermal keratinocytes isolated from transgenic mice
    • Bollag WB, Xiong Y, Ducote J, Harmon CS: Regulation of fos-lacZ fusion gene expression in primary mouse epidermal keratinocytes isolated from transgenic mice. Biochem J 300:263-270, 1994
    • (1994) Biochem J , vol.300 , pp. 263-270
    • Bollag, W.B.1    Xiong, Y.2    Ducote, J.3    Harmon, C.S.4
  • 5
    • 0022391554 scopus 로고
    • A simple quantitative procedure using monolayer cultures for cytotoxicity assays (HTD/NR-90)
    • Borenfreund E, Puerner JA: A simple quantitative procedure using monolayer cultures for cytotoxicity assays (HTD/NR-90). J Tissue Cult Methods 9:7-9, 1984
    • (1984) J Tissue Cult Methods , vol.9 , pp. 7-9
    • Borenfreund, E.1    Puerner, J.A.2
  • 6
    • 0025326163 scopus 로고
    • Calcium-dependent regulation of protein synthesis in intact mammalian cells
    • Brostrom CO, Brostrom MA: Calcium-dependent regulation of protein synthesis in intact mammalian cells. Annu Rev Physiol 52:577-590, 1990
    • (1990) Annu Rev Physiol , vol.52 , pp. 577-590
    • Brostrom, C.O.1    Brostrom, M.A.2
  • 8
    • 0020079553 scopus 로고
    • Thapsigargin and thapsigargicin, two histamine liberating sesquiterpene lactones from Thapsiga garganica. X-ray analysis of the 7,11-epoxide of thapsigargin
    • Christensen SB, Larsen IK, Rasmussen U: Thapsigargin and thapsigargicin, two histamine liberating sesquiterpene lactones from Thapsiga garganica. X-ray analysis of the 7,11-epoxide of thapsigargin. J Org Chem 47:649-652, 1982
    • (1982) J Org Chem , vol.47 , pp. 649-652
    • Christensen, S.B.1    Larsen, I.K.2    Rasmussen, U.3
  • 9
    • 0017809645 scopus 로고
    • Tumor promotion and the induction of epidermal ornithine decarboxylase activity in mechanically stimulated mouse skin
    • Clark-Lewis J, Murray AW: Tumor promotion and the induction of epidermal ornithine decarboxylase activity in mechanically stimulated mouse skin. Cancer Res 38:494-497, 1978
    • (1978) Cancer Res , vol.38 , pp. 494-497
    • Clark-Lewis, J.1    Murray, A.W.2
  • 10
    • 0023631879 scopus 로고
    • Isolation and characterization of the c-fos (rat) cDNA and analysis of post-translational modification in vitro
    • Curran T, Gordon MB, Rubino KC, Sambucetti LC: Isolation and characterization of the c-fos (rat) cDNA and analysis of post-translational modification in vitro. Oncogene 2:79-84, 1987
    • (1987) Oncogene , vol.2 , pp. 79-84
    • Curran, T.1    Gordon, M.B.2    Rubino, K.C.3    Sambucetti, L.C.4
  • 11
    • 0026029316 scopus 로고
    • Patterns of epithelial expression of Fos protein suggest important role in the transition from viable to cornified cell during keratinization
    • Fisher C, Byers MR, Iadarola MJ, Powers EA: Patterns of epithelial expression of Fos protein suggest important role in the transition from viable to cornified cell during keratinization. Development 111:253-258, 1991
    • (1991) Development , vol.111 , pp. 253-258
    • Fisher, C.1    Byers, M.R.2    Iadarola, M.J.3    Powers, E.A.4
  • 13
    • 0027371858 scopus 로고
    • Potassium channel openers stimulate DNA synthesis in mouse epidermal keratinocyte and whole hair follicle cultures
    • Harmon CS, Lutz D, Ducote J: Potassium channel openers stimulate DNA synthesis in mouse epidermal keratinocyte and whole hair follicle cultures. Skin Pharmacol 6:170-178, 1993
    • (1993) Skin Pharmacol , vol.6 , pp. 170-178
    • Harmon, C.S.1    Lutz, D.2    Ducote, J.3
  • 14
    • 0014741374 scopus 로고
    • Studies on the mechanism of skin tumor promotion
    • Hennings H, Boutwell RK: Studies on the mechanism of skin tumor promotion. Cancer Res 30:312-320, 1970
    • (1970) Cancer Res , vol.30 , pp. 312-320
    • Hennings, H.1    Boutwell, R.K.2
  • 15
    • 0018865014 scopus 로고
    • Calcium regulation of growth and differentiation of mouse epidermal cells in culture
    • Hennings H, Michael D, Cheng C, Steinert P, Holbrook KA, Yuspa SH: Calcium regulation of growth and differentiation of mouse epidermal cells in culture. Cell 19:245-254, 1980
    • (1980) Cell , vol.19 , pp. 245-254
    • Hennings, H.1    Michael, D.2    Cheng, C.3    Steinert, P.4    Holbrook, K.A.5    Yuspa, S.H.6
  • 16
    • 0024460388 scopus 로고
    • Subcellular distribution of protein kinase C/phorbol ester receptors in differentiating mouse keratinocytes
    • Isseroff RR, Stephens LE, Gross JL: Subcellular distribution of protein kinase C/phorbol ester receptors in differentiating mouse keratinocytes. J Cell Physiol 141:235-242, 1989
    • (1989) J Cell Physiol , vol.141 , pp. 235-242
    • Isseroff, R.R.1    Stephens, L.E.2    Gross, J.L.3
  • 18
    • 0028242824 scopus 로고
    • Thapsigargin raises intracellular free calcium levels in human keratinocytes and inhibits the coordinated expression of differentiation markers
    • Jones KT, Sharpe GR: Thapsigargin raises intracellular free calcium levels in human keratinocytes and inhibits the coordinated expression of differentiation markers. Exp Cell Res 210:71-76, 1994
    • (1994) Exp Cell Res , vol.210 , pp. 71-76
    • Jones, K.T.1    Sharpe, G.R.2
  • 19
    • 0026328668 scopus 로고
    • Regulation of intracellular free calcium in normal murine keratinocytes
    • Kruszewski FH, Hennings H, Yuspa SH, Tucker RW: Regulation of intracellular free calcium in normal murine keratinocytes. Am J Physiol 261:C767-773, 1991
    • (1991) Am J Physiol , vol.261
    • Kruszewski, F.H.1    Hennings, H.2    Yuspa, S.H.3    Tucker, R.W.4
  • 20
    • 0025880144 scopus 로고
    • Changes in inositol phosphate metabolism are associated with terminal differentiation and neoplasia in mouse keratinocytes
    • Lee E, Yuspa SH: Changes in inositol phosphate metabolism are associated with terminal differentiation and neoplasia in mouse keratinocytes. Carcinogenesis 12:1651-1658, 1991
    • (1991) Carcinogenesis , vol.12 , pp. 1651-1658
    • Lee, E.1    Yuspa, S.H.2
  • 22
    • 0026769568 scopus 로고
    • The role of calcium and protein kinase C in the IgE dependent activation ot phosphatidylcholine specific phospholipase D in a rat mast (RBL 2H3) cell line
    • Lin P, Gilfillan AM: The role of calcium and protein kinase C in the IgE dependent activation ot phosphatidylcholine specific phospholipase D in a rat mast (RBL 2H3) cell line. Eur J Biochem 207:163-168, 1992
    • (1992) Eur J Biochem , vol.207 , pp. 163-168
    • Lin, P.1    Gilfillan, A.M.2
  • 23
    • 0026342829 scopus 로고
    • Participation of postsynaptic PKC in cerebellar long-term depression in culture
    • Linden DJ, Connor JA: Participation of postsynaptic PKC in cerebellar long-term depression in culture. Science 254:1656-1659, 1991
    • (1991) Science , vol.254 , pp. 1656-1659
    • Linden, D.J.1    Connor, J.A.2
  • 24
    • 0021135561 scopus 로고
    • c-myc transcript is induced in rat liver at a very early stage of regeneration or by cycloheximide treatment
    • Makino R, Hayashi K, Sugimura T: c-myc transcript is induced in rat liver at a very early stage of regeneration or by cycloheximide treatment. Nature 310:697-698, 1984
    • (1984) Nature , vol.310 , pp. 697-698
    • Makino, R.1    Hayashi, K.2    Sugimura, T.3
  • 25
    • 0018131121 scopus 로고
    • Stratification, specialization and proliferation of primary keratinocyte cultures
    • Marcelo CL, Kim YG, Kaine JL, Voorhees JJ: Stratification, specialization and proliferation of primary keratinocyte cultures. J Cell Biol 79:356-369, 1978
    • (1978) J Cell Biol , vol.79 , pp. 356-369
    • Marcelo, C.L.1    Kim, Y.G.2    Kaine, J.L.3    Voorhees, J.J.4
  • 26
    • 0025895409 scopus 로고
    • Stimulatory effect of thapsigargin, a non-TPA-type tumor promoter, on arachidonic acid metabolism in the murine keratinocyte line HEL30 and on epidermal cell proliferation in vivo as compared to the effects of phorbol ester TPA
    • Marks F, Hanke B, Thastrup O, Furstenberger G: Stimulatory effect of thapsigargin, a non-TPA-type tumor promoter, on arachidonic acid metabolism in the murine keratinocyte line HEL30 and on epidermal cell proliferation in vivo as compared to the effects of phorbol ester TPA. Carcinogenesis 12:1491-1497, 1991
    • (1991) Carcinogenesis , vol.12 , pp. 1491-1497
    • Marks, F.1    Hanke, B.2    Thastrup, O.3    Furstenberger, G.4
  • 27
    • 0022441860 scopus 로고
    • Role of ion flux in the control of c-fos expression
    • Morgan JI, Curran T: Role of ion flux in the control of c-fos expression. Nature 322:552-555, 1986
    • (1986) Nature , vol.322 , pp. 552-555
    • Morgan, J.I.1    Curran, T.2
  • 28
    • 0021752840 scopus 로고
    • Induction of c-fos gene and protein by growth factors precedes activation of c-myc
    • Muller R, Bravo R, Burckhardt J, Curran T: Induction of c-fos gene and protein by growth factors precedes activation of c-myc. Nature 312:716-720, 1984
    • (1984) Nature , vol.312 , pp. 716-720
    • Muller, R.1    Bravo, R.2    Burckhardt, J.3    Curran, T.4
  • 29
    • 0023904952 scopus 로고
    • Analysis of the stimulative effect of thapsigargin, a non-TPA-type tumour promoter, on arachidonic acid metabolism in rat peritoneal macrophages
    • Ohuchi K, Sugawara T, Watanabe M, Hirasawa N, Tsurufuji S, Fujiki H, Christensen SB, Sugimura T: Analysis of the stimulative effect of thapsigargin, a non-TPA-type tumour promoter, on arachidonic acid metabolism in rat peritoneal macrophages. Br J Pharmacol 94:917-923, 1988
    • (1988) Br J Pharmacol , vol.94 , pp. 917-923
    • Ohuchi, K.1    Sugawara, T.2    Watanabe, M.3    Hirasawa, N.4    Tsurufuji, S.5    Fujiki, H.6    Christensen, S.B.7    Sugimura, T.8
  • 31
    • 0027135597 scopus 로고
    • Ability of the non-phorbol ester-type tumor-promoter thapsigargin to mimic the stimulatory effects of 12-O-tetradecanoylphorbol-13-acetate on ornithine decarboxylase activity, hydroperoxide production, and macromolecule synthesis in mouse epidermis in vivo
    • Perchellet EM, Gali HU, Gao XM, Perchellet J: Ability of the non-phorbol ester-type tumor-promoter thapsigargin to mimic the stimulatory effects of 12-O-tetradecanoylphorbol-13-acetate on ornithine decarboxylase activity, hydroperoxide production, and macromolecule synthesis in mouse epidermis in vivo. Int J Cancer 55:1036-1043, 1993
    • (1993) Int J Cancer , vol.55 , pp. 1036-1043
    • Perchellet, E.M.1    Gali, H.U.2    Gao, X.M.3    Perchellet, J.4
  • 32
    • 0002569886 scopus 로고
    • Dye exclusion tests for cell viability
    • Kruse PF (ed.). Academic Press, New York
    • Phillips HJ: Dye exclusion tests for cell viability. In: Kruse PF (ed.). Tissue Culture, Academic Press, New York, 1973, pp 407-408
    • (1973) Tissue Culture , pp. 407-408
    • Phillips, H.J.1
  • 33
    • 0022575011 scopus 로고
    • A model for receptor-regulated calcium entry
    • Putney JW: A model for receptor-regulated calcium entry. Cell Calcium 7:1-12, 1986
    • (1986) Cell Calcium , vol.7 , pp. 1-12
    • Putney, J.W.1
  • 34
    • 0024531375 scopus 로고
    • Acquisition of competence by resting cells for entry into the DNA synthesis period after incubation with growth factors and protein synthesis inhibitors
    • Rosenwald IB, Makarova GF, Epifanova OI: Acquisition of competence by resting cells for entry into the DNA synthesis period after incubation with growth factors and protein synthesis inhibitors. Dokl Akad Nauk SSR 305:977-980, 1989
    • (1989) Dokl Akad Nauk SSR , vol.305 , pp. 977-980
    • Rosenwald, I.B.1    Makarova, G.F.2    Epifanova, O.I.3
  • 35
    • 0026010287 scopus 로고
    • Regulation of a fos-lacZ fusion gene: A paradigm for quantitative analysis of stimulus-transcription coupling
    • Schilling K, Luk D, Morgan JI, Curran T: Regulation of a fos-lacZ fusion gene: a paradigm for quantitative analysis of stimulus-transcription coupling. Proc Natl Acad Sci USA 88:5665-5669, 1991
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 5665-5669
    • Schilling, K.1    Luk, D.2    Morgan, J.I.3    Curran, T.4
  • 37
    • 0020317949 scopus 로고
    • Correlation between sensitivity to tumor promotion and sustained epidermal hyperplasia of mice and rats treated with TPA
    • Sisskin EE, Gray T, Barrett JC: Correlation between sensitivity to tumor promotion and sustained epidermal hyperplasia of mice and rats treated with TPA. Carcinogenesis 3:403-408, 1982
    • (1982) Carcinogenesis , vol.3 , pp. 403-408
    • Sisskin, E.E.1    Gray, T.2    Barrett, J.C.3
  • 39
    • 0024346141 scopus 로고
    • Activation of calcium entry by the tumor promoter thapsigargin in parotid acinar cells
    • Takemura H, Hughes AR, Thastrup O, Putney JW: Activation of calcium entry by the tumor promoter thapsigargin in parotid acinar cells. J Biol Chem 264:12266-12271, 1989
    • (1989) J Biol Chem , vol.264 , pp. 12266-12271
    • Takemura, H.1    Hughes, A.R.2    Thastrup, O.3    Putney, J.W.4
  • 40
    • 0023829879 scopus 로고
    • Turnover of inositol phospholipids in cultured murine keratinocytes: Possible involvement of inositol triphosphate in cellular differentiation
    • Tang W, Ziboh VA, Isseroff R, Martinez BS: Turnover of inositol phospholipids in cultured murine keratinocytes: possible involvement of inositol triphosphate in cellular differentiation. J Invest Dermatol 90:34-43, 1988
    • (1988) J Invest Dermatol , vol.90 , pp. 34-43
    • Tang, W.1    Ziboh, V.A.2    Isseroff, R.3    Martinez, B.S.4
  • 41
    • 0023095571 scopus 로고
    • The calcium mobilizing and tumour promoting agent, thapsigargin, elevates the platelet cytoplasmic free calcium concentration to a higher steady state level. A possible mechanism of action for the tumour promotion
    • Thastrup O, Foder B, Scharff O: The calcium mobilizing and tumour promoting agent, thapsigargin, elevates the platelet cytoplasmic free calcium concentration to a higher steady state level. A possible mechanism of action for the tumour promotion. Biochem Biophys Res Commun 142:654-660, 1987
    • (1987) Biochem Biophys Res Commun , vol.142 , pp. 654-660
    • Thastrup, O.1    Foder, B.2    Scharff, O.3
  • 45
    • 0025142219 scopus 로고
    • The effect of new potent selective inhibitors of protein kinase C on the neutrophil respiratory burst
    • Twomey B, Muid RE, Nixon JS, Sedgwick AD, Wilkinson SE: The effect of new potent selective inhibitors of protein kinase C on the neutrophil respiratory burst. Biochem Biophys Res Commun 171:1087-1092, 1990
    • (1990) Biochem Biophys Res Commun , vol.171 , pp. 1087-1092
    • Twomey, B.1    Muid, R.E.2    Nixon, J.S.3    Sedgwick, A.D.4    Wilkinson, S.E.5
  • 46
    • 0027530567 scopus 로고
    • Inhibition of protein synthesis and early protein processing by thapsigargin in cultured cells
    • Wong WL, Brostrom MA, Kuznetsov G, Gmitter-Yellen D, Brostrom CO: Inhibition of protein synthesis and early protein processing by thapsigargin in cultured cells. Biochem J 289:71-79, 1993
    • (1993) Biochem J , vol.289 , pp. 71-79
    • Wong, W.L.1    Brostrom, M.A.2    Kuznetsov, G.3    Gmitter-Yellen, D.4    Brostrom, C.O.5
  • 48
    • 0017105686 scopus 로고
    • Stimulated DNA synthesis in mouse epidermal cell cultures treated with 12-O-tetradecanoyl-phorbol-13-acetate
    • Yuspa SH, Ben T, Patterson E, Michael D, Elgio K, Hennings H: Stimulated DNA synthesis in mouse epidermal cell cultures treated with 12-O-tetradecanoyl-phorbol-13-acetate. Cancer Res 36:4062-4068, 1976
    • (1976) Cancer Res , vol.36 , pp. 4062-4068
    • Yuspa, S.H.1    Ben, T.2    Patterson, E.3    Michael, D.4    Elgio, K.5    Hennings, H.6
  • 49
    • 0024454035 scopus 로고
    • Expression of murine epidermal differentiation markers is tightly regulated by restricted calcium concentrations in vitro
    • Yuspa SH, Kilkenny AE, Steinert PM, Roop DR: Expression of murine epidermal differentiation markers is tightly regulated by restricted calcium concentrations in vitro. J Cell Biol 109:1207-1217, 1989
    • (1989) J Cell Biol , vol.109 , pp. 1207-1217
    • Yuspa, S.H.1    Kilkenny, A.E.2    Steinert, P.M.3    Roop, D.R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.