GABAergic inhibition of the pituitary release of adrenocorticotropin and alpha-melanotropin is impaired in dogs with hepatic encephalopathy

Domestic Animal Endocrinology

Volumn 13, Issue 1, 1996, Pages 59-68

  Rothuizen, J ^a   De Kok, Y ^a   Slob, A ^a   Mol, J A ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA; CANIS FAMILIARIS;

EID: 0030055224     PISSN: 07397240     EISSN: None     Source Type: Journal    
DOI: 10.1016/0739-7240(95)00044-5     Document Type: Article

References (48)

1. J. Rothuizen J.A. Mol The pituitary-adrenocortical system in canine hepato-encephalopathy Front Horm Res 17 1987 48 60
2. H.P. Meyer J. Rothuizen Increased free cortisol in plasma in dogs with portosystemic encephalopathy (PSE) Domest Anim Endocrinol 11 1994 317 322
3. J. Rothuizen W.J. Biewenga J.A. Mol Chronic glucocorticoid excess and impaired osmoregulation of vasopressin release in dogs with hepatic encephalopathy Domest Animal Endocrinol 12 1995 13 24
4. P.F. Suter Portal vein anomalies in the dog: their angiographic diagnosis Am J Vet Radiol 16 1995 84 97
5. J. Rothuizen Portosystemic hepatic encephalopathy related with congenital and acquired hepatopathies in the dog C.E. Cornelius Animal Models in Liver Research 1994 Academic Press New York 403 416
6. T.S.G.A.M. Van den Ingh J. Rothuizen Hepatoportal fibrosis in three young dogs Vet Rec 110 1982 575 577
7. W.H.F. Jarrett B.W. O'Neil A new transmissible agent causing acute hepatitis, chronic hepatitis and cirrhosis in the dog Vet Rec 116 1985 629 635
8. S.S. Schenker C.E. Brady Pathogenesis of hepatic encephalopathy H.O. Conn J. Bircher Hepatic Encephalopathy: Management With Lactulose and Related Carbohydrates 1989 Medi-Ed Press East Lansing, MI 15 30
9. J.H. James J.M. Hodgman J.M. Funovics J.E. Fischer Alterations in brain octopamine and brain tyrosine following portacaval anastomosis in rats J Neurochem 270 1976 223 227
10. J.E. Fischer R.J. Baldessarini False neurotransmitters and hepatic failure Lancet 2 1979 75 80
11. R.J. Kemppainen J.L. Sartin In vivo evidence for dopaminergic regulation of the canine pituitary intermediate lobe Acta Endocrinol [Copenh] 113 1986 471 478
12. R.J. Kemppainen C.A. Zerbe J.L. Sartin Regulation and secretion of proopiomelanocortin peptides from isolated perfused dog pituitary pars intermedia cells Endocrinology 124 1988 2208 2217
13. M. Baraldi M.L. Zeneroli Experimental hepatic encephalopathy: changes in the binding of gamma amino butyric acid Science 216 1982 427 431
14. E. Roberts The gamma-aminobutyric acid (GABA) system and hepatic encephalopathy Hepatology 4 1984 342 345
15. M.L. Basset K.D. Mullen P. Skolnick Amelioration of hepatic encephalopathy by pharmacologic antagonism of the BAGAa-benzodiazepine receptor complex in a rabbit model of fulminant hepatic failure Gastroenterology 93 1987 1069 1077
16. J.E. Maddison P. Dodd M. Morrison J.A. Johnston G.C. Farrell Plasma GABA, GABA-like activity and the brain GABA-benzodiazepine receptor complex in rats with chronic hepatic encephalopathy Hepatology 7 1987 621 628
17. M.T. Jones B. Gillham A.R.H. Altaher S.A. Nicholson E.A. Campbell S.M. Watts A. Thody Clinical and experimental studies on the role of GABA in the regulation of ACTH secretion: A review Psychoneuroendocrinology 9 1984 107 123
18. S.M. McCann V. Rettori gamma aminobutyric acid (GABA) controls anterior pituitary hormone secretion G. Racagni A.O. Donoso GABA and Endocrine Function 1986 Raven Press New York 173 189
19. G.B. Melis V. Mais A.M. Paoletti D. Antinori A. De Ruggiero P. Fioretti GABAergic control of anterior pituitary function in humans G. Racagni A.O. Donoso GABA and Endocrine Function 1986 Raven Press New York 219 242
20. J.P. Loeffler B.A. Demeneix C.W. Pitius N. Kley K.D. Haegele V. Höllt GABA differentially regulates the gene expression of proopiomelanocortin in rat intermediate and anterior pituitary Peptides 7 1986 253 258
21. I. Miguez G. Atienza M. Aldegunde Inhibitory effect of intracerebroventricular administration of GABA on corticosterone release in conscious non-stressed male rats Neuroendocrinol Lett 10 1988 45 50
22. B receptors on porcine pars intermedia cells in primary culture: functional role in modulating peptide release Neuroscience 17 1986 1275 1285
23. B.M.L. Verburg-van Kemenade M. Tappaz L. Paut B.G. Jenks GABAergic regulation of melanocytestimulating hormone secretion from the pars intermedia of Xenopus laevis: Immunocytochemical and physiological evidence Endocrinology 118 1986 260 267
24. S.A. Tomiko P.S. Taraskevich W.W. Douglas GABA acts directly on cells of pituitary pars intermedia to alter hormone output Nature 301 1983 706 707
25. A. Rijnberk J.A. Mol M.M. Kwant R.J.M. Croughs Effects of bromocriptin on corticotrophin melanotrophin and corticosteroid secretion in dogs with pituitary-dependent hyperadrenocorticism J Endocrinol 118 1988 271 277
26. A. Rijnberk A. Van Wees J.A. Mol Assessment of two tests for the diagnosis of canine hyperadrenocorticism Vet Re 122 1988 178 180
27. J.A. Mol A. Slob D.J. Middleton A. Rijnberk Release of adrenocorticotropin, melanotropin and β-endorphin by pituitary tumors of dogs with pituitary-dependent hyperadrenocorticism Front Horm Res 17 1987 61 70
28. N. Pivac D. Pericic Inhibitory effect of diazepam on the activity of the hypothalamic-pituitary-adrenal axis in female rats J Neural Transm Gen Sec 92 1993 173 186
29. S. Kongsamut I. Shibuya W.W. Douglas Why are several inhibitory transmitters present in the innervation of pituitary melanotrophs? Actions and interactions of dopamine, GABA and n neuropeptide Y on secretion from neurointermediate lobes of Xenopus laevis Neuroendocrinology 54 1991 599 606
30. S.W.J. Lamberts T. Verleun E.G. Bons P. Uitterlinden R. Oosterom Effects of cyproheptadine, desmethylcroroheptadine, τ-amino-butyric acid and sodium valproate on adrenocorticotrophin secretion by cultured pituitary tumour cells from three patients with Nelson's syndrome J Endocrinol 96 1983 401 406
31. S.W. Lamberts Intermediate lobe pituitary tumours as a cause of Cushing's disease? A review on the role of the intermediate lobe in man Front Horm Res 17 1987 93 111
32. L.C. Saland J.A. Carr A. Samora D. Tejeda Benzodiazepine suppression of cortocotropin releasing factor (CRF)-induced beta-endorphin release from rat neurointermediate pituitary Peptides 13 1992 913 917
33. S.R. De Barioglio N. Lezcano M.E. Celis Alpha MSH-induced excessive grooming behavior involves a GABAergic mechanism Peptides 12 1991 203 205
34. I. Shibuya S. Kongsamut W.W. Douglas Studies on pituitary melanotrophs reveal the novel GABA-B antagonist CGP 35-348 to be the first such compound effective on endocrine cells 2nd Ed. Proc R Soc Lond B Biol Sci 243 1991 129 137
35. O. Brüstle Ch. Pilgrim W. Gaymann I. Reisert Abundant GABAergic innervation of rat posterior pituitary revealed by inhibition of GABA-transaminase Cell Tissue Res 251 1988 59 64
36. E. Louiset F.H. Van de Put M.C. Tonon C. Basille B.G. Jenks H. Vaudry L. Cazin Electrophysiological evidence for the existence of GABA-A receptors in cultured frog melanotrophs Brain Res 517 1990 151 156
37. M.C. Tonon S. Adjeroud M. Lamacz E. Louiset J.M. Danger L. Desrues L. Cazin P. Nicolas H. Vaudry Central-type benzodiazepines and the octadecaneuropeptide modulate the effects of GABA on the release of alpha-melanocyte-stimulating hormone from frog neurointermediate lobe in vitro Neuroscience 31 1989 485 493
38. R. Stolp H.W.M. Steinbusch A. Rijnberk R.J.M. Croughs Organization of ovine corticotrophin-releasing factor immunoreactive neurons in the canine hypothalamo-pituitary system Neurosci Lett 74 1987 337 342
39. C. Blasquez S. Jegou D. Tranchand Bunel C. Delbende P. Braquet H. Vaudry Central-type benzodiazepines inhibit release of alpha-melanocyte-stimulating hormone from the rat hypothalamus Neuroscience 42 1991 509 516
40. J. Mabley C.P. Wayman J.F. Wilson Endogenous gamma-aminobutyric acid tonically inhibits release of alpha-melanocyte-stimulating hormone from rat hypothalamic slices Eur J Pharmacol 209 1991 127 129
41. K.D. Mullen K.M. Szanter P.G. Galloway CSF of patients with hepatic encephalopathy (HE) contains significant benzodiazepine (BZ) binding activity. Correlations with postmortem cortical BZ binding studies Hepatology 7 1987 1103 1111
42. K.D. Mullen K.M. Szauter K. Kaminsky P.D. Tolentino A.J. McCullogh Detection and characterization of endogenous benzodiazepine activity in both animal models and humans with hepatic encephalopathy R.F. Butterworth G.P. Layrargues Hepatic Encephalopathy—Pathophysiology and Treatment 1989 Humana Press Clifton NY 287 294
43. G. Bakti H.V. Fisch G. Kazlganis Mechanism of the excessive sedative response of cirrhotics to benzodiazepines: model experiments with triazolan Hepatology 7 1987 629 638
44. M.L. Zeneroli M. Baraldi E. Ventura C. Vezzelli O. Tofanetti M. Germini I. Casciarri Alterations of GABA-A and dopamine D-2 receptors in dogs with portal-systemic encephalopathy Life Sci 48 1991 37 50
45. S.H. Gammal A.S. Basile D. Geller P. Skolnick E.A. Jones Reversal of the behavioural and electrophysiological abnormalities of an animal model of hepatic encephalopathy by benzodiazepine receptor ligands Hepatology 11 1990 371 378
46. G. Bansky P.J. Meier E. Riederer H. Walser W.H. Ziegler M. Schmid Effect of the benzodiazepine receptor antagonist flumazenil in hepatic encephalopathy in humans Gastroenterology 97 1989 744 750
47. P. Ferenci G. Grimm S. Meryn A. Gangl Successful longtime treatment of portal-systemic encephalopathy by the benzodiazepine antagonist flumazenil Gastroenterology 96 1989 240 243
48. E.R. De Kloet Brain corticosteroid receptor balance and homeostatic control Front Neuroendocrinol 2 1991 95 164