Domain structure, stability and interactions in streptokinase

European Journal of Biochemistry

Volumn 239, Issue 2, 1996, Pages 333-339

  Medved, Leonid V ^a,b   Solovjov, Dmitry A ^b   Ingham, Kenneth C ^a  

^a HOLLAND LABORATORY   (United States)

^b PALLADIN INSTITUTE OF BIOCHEMISTRY   (Ukraine)

Author keywords

Denaturation; Domains; Fragments; Scanning calorimetry; Streptokinase

Indexed keywords

STREPTOKINASE;

ARTICLE; CHEMICAL STRUCTURE; DIFFERENTIAL SCANNING CALORIMETRY; PHASE TRANSITION; PRIORITY JOURNAL; PROTEIN DENATURATION; PROTEIN DOMAIN; PROTEIN STRUCTURE; SEQUENCE ANALYSIS;

EID: 0030055048     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1432-1033.1996.0333u.x     Document Type: Article

References (27)

1. Castellino, F. J. (1979) A unique enzyme-protein substrate modifier reaction: plasmin/streptokinase interaction. Trends Biochem. Sci. 4, 1-5.
2. Damaschun, G., Damaschun, H., Gast, K., Gerlach, D., Misselwitz, R., Weltle, H. & Zirwer, D. (1992) Streptokinase is a flexible multidomain protein. Eur. Biophys. J. 20, 355-361.
3. Edelhoch, H. (1967) Spectroscopic determination of tryptophan and tyrosine in proteins. Biochemistry 6, 1948-1954.
4. Filimonov, V. V., Potekhin, S. A., Matveev, S. V. & Privalov, P. L. (1982) Thermodynamic analysis of scanning microcalorimetry data. I. Algorithms for deconvolution of heat absorption curves. Mol. Biol. (Mosc.) 16, 551-562.
5. Gaffney, P. J. (1994) First- and second-generation thrombolytic agents: mechanistic and clinical capability, in Coronary thrombosis: intracardiac thrombosis (Perez-Gomez, E., Prentice, C. R. M. & Meyer, J., eds) pp. 101-113, Raven Press, New York.
6. Gill, S. C. & von Hippel, P. H. (1989) Calculation of protein extinction coefficients from amino acid sequence data. Anal. Biochem. 182, 319-326.
7. Jackson, K. W. & Tang, J. (1982) Complete amino acid sequence of streptokinase and its homology with serine proteases. Biochemistry 21, 6620-6625.
8. Medved, L. V., Busby, T. F. & Ingham, K. C. (1989) Calorimetric investigation of the domain structure of human complement Cls: Reversible unfolding of the short consensus repeat units. Biochemistry 28, 5408-5414.
9. Medved, L. V., Orthner, C. L., Lubon, H., Lee, T. K., Drohan, W. N. & Ingham, K. C. (1995) Thermal stability and domain-domain interactions in natural and recombinant protein C. J. Biol. Chem. 270, 13652-13659.
10. Misselwitz, R., Kraft, R., Kostka, S., Fabian, H., Welfle, K., Pfeil, W., Welfle, H. & Gerlach, D. (1992) Limited proteolysis of streptokinase and properties of some fragments. Int. J. Biol. Macromol. 14, 107-116.
11. Novokhatny, V. V., Ingham, K. C. & Medved, L. V. (1991) Domain structure and domain domain interactions of recombinant tissue plasminogen activator. J. Biol. Chem. 266, 12994-13002.
12. Novokhatny, V., Medved, L., Mazar, A., Marcotte, P., Henkin, J. & Ingham, K. (1992) Domain structure and interactions of recombinant urokinase-type plasminogen activator. J. Biol. Chem. 267, 3878-3885.
13. Novokhatny, V. V., Medved, L. V., Mazar, A. & Ingham, K. C. (1993) Effect of tethered peptidylchloromethylketone inhibitors on thermal stability and domain interactions of urokinase and other serine proteases. J. Biol. Chem. 268, 17211-17218.
14. Pace, C. N., Vajdos, F., Fee, L., Grimsley, G. & Gray, T. (1995) How to measure and predict the molar absorption coefficient of a protein. Protein Sci. 4, 2411-2423.
15. Ponting, C. P., Marshall, J. M. & Cederholm-Williams, S. A. (1992) Plasminogen: a structural review. Blood Coagul. Fibrinolysis 3, 605-614.
16. Privalov, P. L. & Potekhin, S. A. (1986) Scanning microcalorimetry in studying temperature-induced changes in proteins. Methods Enzymol. 131, 4-51.
17. Privalov, P. L. & Makhatadze, G. I. (1990) Heat capacity of proteins. II. Partial molar heat capacity of the unfolded polypeptide chain of proteins: protein unfolding effect. J. Mol. Biol. 213, 385-391.
18. Radek, J. T. & Castellino, F. J. (1989) Conformational properties of streptokinase. J. Biol. Chem. 264, 9915-9922.
19. Reed, G. L., Lin, L.-F., Parhami-Seren, B. & Kussie, P. (1995) Identification of plasminogen binding region in streptokinase that is necessary for the creation of a functional streptokinase-plasminogen activator complex. Biochemistry 34, 10266-10271.
20. Richardson, J. S. (1981) The anatomy and taxonomy of protein structure. Adv. Protein Chem. 34, 167-339.
21. Rodriguez, P., Fuentes, D., Munoz, E., Rivero, D., Orta, D., Alburquerque, S., Perez, S., Besada, V. & Herrera, L. (1994) The streptokinase domain responsible for plasminogen binding. Fibrinolysis 4, 276-285.
22. Rodriguez, P., Fuentes, P., Barro, M., Alvarez, J. G., Munoz, E., Collen, D. & Lijnen, H. R. (1995) Structural domains of streptokinase involved in interaction with plasminogen. Eur. J. Biochem. 229, 83-90.
23. Shi, G.-Y., Chang, B., Chen, S.-M., Wu, D.-H. & Wu, H.-L. (1994) Function of streptokinase fragments in plasminogen activation. Biochem. J. 304, 235-241.
24. Siefring, G. E. J. & Castellino, F. J. (1976) Interaction of streptokinase with plasminogen. Isolation and characterization of a streptokinase degradation product. J. Biol. Chem. 251, 3913-3920.
25. Teuten, A. J., Broadhurst, R. W., Smith, R. A. G. & Dobson, C. M. (1993) Characterization of structural and folding properties of streptokinase by n.m.r. spectroscopy. Biochem. J. 290, 313-319.
26. Vysotchin, A., Medved, L. & Ingham, K. (1993) Domain structure and domain-domain interactions in human coagulation factor IX. J. Biol. Chem. 268, 8436-8446.
27. Welfle, K., Pfeil, W., Misselwitz, R., Welfle, H. & Gerlach, D. (1992) Conformational properties of streptokinase - differential scanning calorimetric investigations. Int. J. Biol. Macromol. 14, 19-22.