Influence of spatially heterogeneous background activity on 'hot object' quantitation in brain emission computed tomography

Journal of Computer Assisted Tomography

Volumn 20, Issue 4, 1996, Pages 680-687

  Links, Jonathan M ^a   Zubieta, Jon Kar ^a   Meltzer, Carolyn Cidis ^a   Stumpf, Martin J ^a   Frost, J James ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Magnetic resonance imaging, physics and instrumentation; Quantitation; Recovery coefficients

Indexed keywords

BRAIN; COMPUTERIZED TOMOGRAPHY; MAGNETIC RESONANCE IMAGING; RECOVERY;

ACTIVITY CONCENTRATION; CORRECTION SCHEMES; EMISSION COMPUTED TOMOGRAPHY; GRAY MATTER; MAGNETIC RESONANCE IMAGING PHYSICS; MAGNETIC RESONANCE IMAGING, PHYSIC AND INSTRUMENTATION; QUALITATIVE AND QUANTITATIVE ANALYSIS; QUANTITATION; RECOVERY COEFFICIENTS; SIMPLE++;

HAZARDOUS MATERIALS SPILLS;

ARTICLE; BIOPHYSICS; BRAIN SCINTISCANNING; IMAGE ANALYSIS; IMAGE RECONSTRUCTION; INSTRUMENTATION; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL;

EID: 0030054873     PISSN: 03638715     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004728-199607000-00033     Document Type: Article

References (12)

1. Hoffman EJ, Huang S-C, Phelps ME. Quantitation in positron emission computed tomography: 1. Effect of object size. J Camput Assist Tomogr 1979;3:299-308.
2. Mazziotta JC, Phelps ME, Plummer D, Kuhl DE. Quantitation in positron emission computed tomography: 5. Physicalanatomical effects. J Comput Assist Tomogr 1981;5:734-43.
3. Kassler RM, Ellis JR, Eden M. Analysis of emission tomographic scan data: limitations imposed by resolution and background. J Comput Assist Tomogr 1984;8:514-22.
4. Bendriem B, Dewey SL, Schlyer DJ, Wolf AP, Volkow ND. Quantitation of the human basal ganglia with positron emission tomography: a phantom study of the effect of contrast and axial positioning. IEEE Trans Med Imag 1991;10:216-22.
5. Yu D-C, Huang S-C, Grafton ST, et al. Methods for improving quantitation of putamen uptake constant of FDOPA in PET studies. J Nucl Med 1993;34:679-88.
6. Mueller-Gaertner HW, Links JM, Prince J, et al. Measurement of radiotracer concentration in brain gray matter using positron emission tomography: MRI-based correction for partial volume effects. J Cereb Blood Flow Metab 1992;12: 571-83.
7. Ma Y, Kamber M, Evans AC. 3D simulation of PET brain images using segmented MRI data and positron tomograph characteristics. Comput Med Imag Graph 1993;17:365-71.
8. Kojima A, Matsumoto M, Takahashi M, Hirota Y, Yoshida H. Effect of spatial resolution on SPECT quantification values. J Nucl Med 1989;30:508-14.
9. Shao L, Billings J, Pfeiffer N, Kung HF. Concentration recovery for SPECT SNS dopamine-receptor studies for monkeys. Med Phys 1994;21:675-81.
10. Meltzer CC, Zubieta JK, Links JM, Brakeman P, Stumpf MJ, Frost JJ. MRI-based correction for PET partial volume effects in the presence of heterogeneity in gray matter radioactivity [Abstract]. J Nucl Med 1994;35:197P.
11. Zubieta JK, Meltzer CC, Links JM, Stumpf MJ, Frost JJ. Correction for PET estimation of tracer activity in small structures with MRI-defined volumes [Abstract]. J Nucl Med 1995;36:115P.
12. Carson RE, Yan Y, Daube-Witherspoon ME, Freedman N, Bacharach SL, Herscovitch P. An approximation formula for the variance of PET region-of-interest values. IEEE Trans Med Imag 1993;12:240-50.