Limited heterogeneity of biased T-cell receptor Vβ gene usage in lung but not blood T cells in active pulmonary sarcoidosis

Immunology

Volumn 88, Issue 4, 1996, Pages 516-523

  Silver, R F ^a,c   Crystal, R G ^b,d   Moller, D R ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^c CASE WESTERN RESERVE UNIVERSITY   (United States)

^d WEILL CORNELL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; T LYMPHOCYTE RECEPTOR;

ADULT; AMINO ACID SEQUENCE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GRANULOMA; HUMAN; LUNG SARCOIDOSIS; MALE; PRIORITY JOURNAL; T LYMPHOCYTE; T LYMPHOCYTE RECEPTOR GENE;

EID: 0030054472     PISSN: 00192805     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2567.1996.d01-683.x     Document Type: Article

References (42)

1. MITCHELL D.N. & SCADDING J.G. (1974) Sarcoidosis. Am Rev Respir Dis 110, 774.
2. HUNNINGHAKE G.W. & CRYSTAL R.G. (1981) Pulmonary sarcoidosis: a disorder mediated by excess helper T-lymphocyte activity at sites of disease activity. N Engl J Med 305, 429.
3. SEMENZATO G., AGOSTINI C., TRENTIN L. et al. (1984) Evidence of cells bearing interleukin-2 receptor at sites of disease activity in sarcoid patients. Clin Exp Immunol 57, 331.
4. COSTABEL U., BROSS K.J., RUHLE K.H., LOHR G.W. & MATTHYS H. (1985) Ia-like antigens on T-cells and their subpopulations in pulmonary sarcoidosis and in hypersensitivity pneumonitis. Am Rev Respir Dis 131, 337.
5. DU BOIS R.M., KIRBY M., BALBI B., SALTINI C. & CRYSTAL R.G. (1992) T-lymphocytes that accumulate in the lung in sarcoidosis have evidence of recent stimulation of the T-cell antigen receptor. Am Rev Respir Dis 154, 1205.
6. KONISHI K., MOLLER D.R., SALTINI C., KIRBY M. & CRYSTAL R.G. (1988) Spontaneous expression of the interleukin 2 receptor gene and presence of functional interleukin 2 receptors on T lymphocytes in the blood of individuals with active pulmonary sarcoidosis. J Clin Invest 82, 775.
7. MOLLER D.R., KONISHI K., KIRBY M., BALBI B. & CRYSTAL R.G. (1988) Bias toward use of a specific T cell receptor β-chain variable region in a subgroup of individuals with sarcoidosis. J Clin Invest 82, 1183.
8. BALBI B., MOLLER D.R., KIRBY M., HOLROYD K.J. & CRYSTAL R.G. (1990) Increased numbers of T lymphocytes with γδ-positive antigen receptors in a subgroup of individuals with pulmonary sarcoidosis. J Clin Invest 85, 1353.
9. TAMURA N., HOLROYD K.J., BANKS T., KIRBY M., OKAYAMA H. & CRYSTAL R.G. (1990) Diversity in junctional sequences associated with the common human Vγ9 and Vδ2 gene segments in normal blood and lung compared with the limited diversity in a granulomatous disease. J Exp Med 172, 169.
10. + T lymphocytes in bronchoalveolar lavage fluid from sarcoidosis patients correlates with HLA-DR3. Eur J Immunol 22, 129.
11. FORMAN J.D., KLEIN J.T., SILVER R.F., LIU M.C., GREENLEE B.M. & MOLLER D.R. (1994) Selective activation and accumulation of oligoclonal Vβ-specific T-cells in active pulmonary sarcoidosis. J Clin Invest 94, 1533.
12. FORRESTER J.M., WANG Y., RICALTON N. et al. (1994) TCR expression of activated T cell clones in the lungs of patients with pulmonary sarcoidosis. J Immunol 153, 4291.
13. BELLOCQ A., LECOSSIER D., PIERRE-AUDIGIER C., TAZI A., VALEVRE D. & HANCE A.J. (1994) T cell receptor repertoire of T lymphocytes recovered from the lung and blood of patients with sarcoidosis. Am J Respir Crit Care Med 149, 646.
14. KLEIN J.T., HORN T.D., FORMAN J.D., SILVER R.F., TEIRSTEIN A.L. & MOLLER D.R. (1995) Selection of oligoclonal Vβ-specific T-cells in the intradermal response to Kveim Siltzbach reagent in individuals with sarcoidosis. J Immunol 154, 1450.
15. FINK P., MATIS A.L., MCELLIGOTT L.D., BOOKMAN M. & HEDRICK M.S. (1986) Correlations between T cell specificity and the structure of the antigen receptor. Nature 321, 219.
16. WUCHERPFENNIG K.W., OTA K., ENDO N. et al. (1990) Shared human T cell receptor Vβ usage to immunodominant regions of myelin basic protein. Science 248, 1016.
17. VAN SCHOOTEN W.C.A., Ko J.L., VAN DER STOEP N. et al. (1992) T-cell receptor β-chain gene usage in the T-cell recognition of Mycobacterium leprae antigens in one tuberculoid leprosy patient. Proc Natl Acad Sci USA 89, 11244.
18. HENWOOD J., LOVERIDOE J., BELL J.I. & GASTON J.S. (1993) Restricted T-cell receptor expression by human T cell clones specific for mycobacterial 65-kDa heat-shock protein: selective in vivo expansion of T cells bearing defined receptors. Eur J Immunol 23, 1256.
19. Moss P.A.H., MOOTS R.J., ROSENBERG W.M.C. et al. (1991) Extensive conservation of α and β chains of the human T-cell antigen receptor recognizing HLA-A2 and influenza A matrix peptide. Proc Natl Acad Sci USA 88, 8987.
20. BOITEL B., ERMONAL M., PANINA-BORDIONON P., MARIUZZA R., LANZAVECCHIA A. & ACUTO O. (1992) Preferential Vβ gene usage and lack of junctional sequence conservation among human T cell receptors specific for a tetanus toxin-derived peptide: evidence for a domiannt role of a germline-encoded V region in antigen/major histocompatibility complex recognition. J Exp Med 175, 765.
21. HIBBERD M.L., WONG F.S., NICHOLSON L.B. & DEMAINE A.G. (1993) Analysis of human T-cell receptor Vβ gene usage following immunization to tetanus toxoid in vivo. Immunology 79, 398.
22. WINOTO A., URBAN J.L., LAN N.C., GOVERMAN J., HOOD L. & HANSBURO D. (1986) Predominant use of a Va gene segment in mouse T-cell receptors for cytochrome c. Nature 324, 679.
23. DAVIS M.M. & BJORKMAN P.J. (1988) T-cell antigen receptor genes and T-cell recognition. Nature 334, 395.
24. HERMAN A., KAPPLER J.W., MARRACK P. & PULLEN A.M. (1991) Superantigens: mechanism of T-cell stimulation and role in immune responses. Annu Rev Immunol 9, 745.
25. ACUTO O., CAMPEN T.J., ROYER H.D., HUSSEY R.E., POOLE C.B. & REINHERZ E.L. (1985) Molecular analysis of T cell receptor (Ti) variable region (V) gene expression: evidence that a single Ti βgene family can be used in formation of V domains on phenotypically and functionally diverse T cell populations. J Exp Med 161, 1326.
26. CHOMCZYNSKI P. & SACCHI N. (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162, 156.
27. SIU G., STRAUSS E.C., LAI E. & HOOD L.E. (1986) Analysis of a human Vβ gene subfamily. J Exp Med 164, 1600.
28. SAMBROOK J., FRITSCH E.F. & MANIATIS T. (1989) Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory Press.
29. JORGENSEN J.L., ESSER U., FAZEKAS DE ST GROTH B., REAY P.A. & DAVIS M.M. (1992) Mapping T-cell receptor-peptide contacts by variant peptide immunization of single-chain transgenics. Nature 355, 224.
30. CHOI Y., LAFFERTY J.A., CLEMENTS J.R. et al. (1990) Selective expansion of T-cells expressing Vβ2 in toxic shock syndrome. J Exp Med 172, 981.
31. + T-cells in mice tolerant to Staphylococcus aureus enterotoxin B. Nature 349, 245.
32. PALJARD X., WEST S.G., LAFFERTY J.A., CLEMENTS J.R., KAPPLER J.W., MARRACK P. & KOTZIN B.L. (1991) Evidence for the effects of a superantigen in rheumatoid arthritis. Science 253, 325.
33. HOWELL M.D., DIVELEY J.P., LUNDEEN K.A. et al. (1991) Limited T-cell receptor β-chain heterogeneity among interleukin 2 receptor-positive synovial T cells suggests a role for superantigen in rheumatoid arthritis. Proc Natl Acad Sci USA 88, 10921.
34. LEHMANN P.V., FORSTHUBER T., MILLER A. & SERCARZ E.E. (1992) Spreading of T-cell autoimmunity to cryptic determinants of an autoantigen. Nature 358, 155.
35. OFFNER H., BUENAFE A.C., VAINIENE M. et al. (1993) Where, when, and how to detect biased expression of disease-relevant Vβ genes in rats with experimental autoimmune encephalitis. J Immunol 151, 506.
36. + T-cells in Crohn's Disease. J Clin Invest 85, 1770.
37. OHMEN J.D., BARNES P.F., GRISSO C.L., BLOOM B.R. & MODLIN R.L. (1994) Evidence for a superantigen in human tuberculosis. Immunity 1, 35.
38. + T cells respond to mycobacterial heat shock proteins. Science 340, 309.
39. UYEMURA K., OHMEN J.D., GRISSO C.L. et al. (1992) Limited T-cell receptor β-chain diversity of a T-helper cell type 1-like response to mycobacterium leprae. Infect Immun 60, 4542.
40. WANG X., GOLKAR L., UYEMURA K. et al. (1993) T-cells bearing Vβ6 T-cell receptors in the cell-mediated immune response to Mycobacterium leprae. J Immunol 151, 7105.
41. STATON J.M., DENCH J.E., CURRIE B. et al. (1995) Expression and immune recognition of stress proteins in sarcoidosis and other chronic interstitial lung diseases. Immunol Cell Biol 73, 23.
42. KAUFMANN S.H.E. (1990) Heat shock proteins and the immune response. Immunol Today 11, 129.