Preference for diazepam, but not buspirone, in moderate drinkers

Psychopharmacology

Volumn 123, Issue 2, 1996, Pages 154-163

  Evans, Suzette M ^a,c   Griffiths, Roland R ^a   De Wit, Harriet ^b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

^c NEW YORK STATE PSYCHIATRIC INSTITUTE   (United States)

Author keywords

Abuse liability; Anxiolytic; Buspirone; Choice; Diazepam; Drug abuse; Humans; Reinforcement; Self administration; Subjective effects

Indexed keywords

ANXIOLYTIC AGENT; BUSPIRONE; DIAZEPAM; PLACEBO;

ALCOHOL CONSUMPTION; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG ABUSE; DRUG CAPSULE; DRUG PREFERENCE; FEMALE; HUMAN; HUMAN EXPERIMENT; MALE; ORAL DRUG ADMINISTRATION; PERFORMANCE; PHARMACEUTICS; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RATING SCALE; REINFORCEMENT; SEDATION;

ADULT; ALCOHOL DRINKING; ANXIETY; BUSPIRONE; DIAZEPAM; FATIGUE; FEMALE; HUMANS; MALE; TIME FACTORS;

EID: 0030054139     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02246172     Document Type: Article

References (50)

1. Aranko K, Matilla MJ, Bordignon D (1985) Psychomotor effects of alprazolam and diazepam during acute and subacute treatment, and during the follow-up phase. Acta Pharmacol Toxicol 56: 364-372
2. Ashton H (1991) Protracted withdrawal syndromes from benzodiazepines. J Subst Abuse Treat 8: 19-28
3. Balster RL (1990) Abuse potential of buspirone and related drugs. J Clin Psychopharmacol 10: 31s-37s
4. Balster RL, Woolverton, WI. (1982) Intravenous buspirone self-administration in rhesus monkeys. J Clin Psychiatry 43: 34-37
5. Barnas C, Rossmann M, Roessler H, Reimer Y, Fleischhacker WW (1992) Benzodiazepines and other psychoactive drugs abused by patients in a methadone maintenance program: familiarity and preference. J Clin Psychopharmacol 12: 397-402
6. Bond A, Lader M, Shrotriva R (1983) Comparative effects of a repeated dose regime of diazepam and buspirone on subjective ratings, psychological tests and the EEC. Eur J Clin Pharmacol 24: 463-467
7. Busto U, Simpkins MA, Sellers EM, Sisson B, Segal R (1983) Objective determination of benzodiazepine use and abuse in alcoholics. Br J Addict 78: 429-435
8. Ciraulo DA, Sands BF, Shader RI (1988) Critical review of liability for benzodiazepine abuse among alcoholics. Am J Psychiatry 145: 1501-1506
9. Cole JO, Orzack MH, Bcake B, Bird M, Bar-Tal Y (1982) Assessment of the abuse liability of buspirone in recreational sedative users. J Clin Psychiatry 43 [12(Sec. 2)]: 69-74
10. Derogatis L (1983) SCL-90-R manual-II. Clinical Psychometric Research, Towson, Md.
11. de Wit H (1991) Diazepam preference in males with and without an alcoholic first-degree relative. Alcohol Clin Exp Res 15: 593-600
12. de Wit H, Griffiths RR (1991) Testing the abuse liability of anxiolytic and hypnotic drugs in humans. Drug Alcohol Depend 28: 83-111
13. de Wit H, Johanson CE, Uhlenhuth EH (1984a) Reinforcing properties of lorazepam in normal volunteer subjects. Drug Alcohol Depend 13:31-41
14. de Wit H, Uhlenhuth EH, Johanson CE (1984b) Lack of preference for flurazepam in normal volunteers. Pharmacol Biochem Behav 21: 865-869
15. de Wit H, Uhlenhuth EH, Pierri J, Johanson CE (1984c) Preference for pentobarbital and diazepam in normal volunteer subjects. Fed Proc 43: 931
16. de Wit H, Uhlenhuth EH, Hedeker D, McCracken SM, Johanson CE (1986) Lack of preference for diazepam in anxious volunteers. Arch Gen Psychiatry 43: 533-541
17. de Wit H, Pierri J, Johanson CE (1989) Reinforcing and subjective effects of diazepam in nondrug-abusing volunteers. Pharmacol Biochem Behav 33: 205-213
18. Erwin CW, Linnoila M, Hartwell J, Erwin A, Guthrie S (1986) Effects of buspirone and diazepam, alone and in combination with alcohol, on skilled performance and evoked potentials. J Clin Psychopharmacol 6: 199-209
19. Feighner JP, Merideth CH, Hendrickson GA (1982) A double-blind comparison of buspirone and diazepam in outpatients with generalized anxiety disorder. J Clin Psychiatry 43: 103-107
20. Foltin RW, Evans SM (1993) Performance effects of drugs of abuse: a methodological survey. Hum Psychopharmacol 8: 9-19
21. Ghoncim MM, Mewaldt SP (1990) Benzodiazepines and human memory: a review. Anesthesiology 72: 926-938
22. Goldberg HL, Finnerty R (1982) Comparison of buspirone in two separate studies. J Clin Psychiatry 43: 87-91
23. Griffith JD, Jasinski DR, Casten GP, McKinney GR (1986) Investigation of the abuse liability of buspirone in alcohol-dependent patients. Am J Med 80 [suppl. 3B]: 30-35
24. Griffiths RR, Bigelow GE, Liebson I (1979) Human drug self-administration: double-blind comparison of pentobarbital, diazepam, chlorpromazine and placebo. J Pharmacol Exp Ther 210: 301-310
25. Griffiths RR, Bigelow GE, Liebson I, Kaliszak JE (1980) Drug preference in humans: double-blind choice comparison of pentobarbital, diazepam and placebo. J Pharmacol Exp Ther 215: 649-661
26. Griffiths RR, McLeod DR, Bigelow GE, Liebson IA, Roache JD (1984a) Relative abuse liability of diazepam and oxazepam: behavioral and subjective dose effects. Psychopharmacology 84: 147-154
27. Griffiths RR, McLeod DR, Bigelow GE, Liebson IA, Roache JD, Nowowicski P (1984b) Comparison of diazepam and oxazepam: preference, liking and extent of abuse. J Pharmacol Exp Ther 229: 501-508
28. Griffiths RR, Lamb RJ, Sannerud CA, Ator NA, Brady JV (1991) Self-injection of barbiturates, benzodiazepines and other sedative-anxiolytics in baboons. Psychopharmacology 103:154-161
29. Iguchi MY, Handelsman L, Bickel WB, Griffiths RR (1993) Benzodiazepine and sedative use/abuse by methadone maintenance clients. Drug Alcohol Depend 32: 257-266
30. Lader M (1982) Psychological effects of buspirone. J Clin Psychiatry 43: 62-67
31. Lader M (1991) Can buspirone induce rebound, dependence or abuse? Br J Psychiatry 159 [suppl. 12]: 62-67
32. Linnoila M, Stapelton JM, Lister R, Moss H, Lane E, Granger A, Eckardt MJ (1990) Effects of single doses of alprazolam and diazepam, alone and in combination with ethanol, on psychomotor and cognitive performance and on autonomic nervous system reactivity in healthy volunteers. Eur J Clin Pharmacol 39: 21-28
33. Lucki I, Rickels K, Giesecke MA, Geller A (1987) Differential effects of the anxiolytic drugs, diazepam and buspirone, on memory function. Br J Clin Pharmacol 23: 207-211
34. Mattila M, Aranko K, Mattila MJ (1982) Acute effects of buspirone and alcohol on psychomotor skills. J Clin Psychiatry 43: 56-60
35. Mattila M, Seppålå T, Mattila MJ (1986) Combined effects of buspirone and diazepam on objective and subjective tests of performance in healthy volunteers. Clin Pharmacol Ther 40: 620-626
36. McCracken SG, de Wit H, Uhlenhuth EH, Johanson CE (1990) Preference for diazepam in anxious adults. J Clin Psychopharmacol 10: 190-196
37. McNair DM, Lorr M, Droppleman LF (1971) Profile of mood states (manual). Educational and Industrial Testing Services, San Diego, CA
38. New JS (1990) The discovery and development of buspirone: a new approach to the treatment of anxiety. Med Res Rev 10: 283-326
39. Pecknold JC, Matas M, Howarth BG, Ross C, Swinson R, Vezeau C, Ungar W (1989) Evaluation of buspirone as an antianxiety agent: buspirone and diazepam versus placebo. Can J Psychiatry 34: 766-771
40. Rickels K, Weisman K, Norstad N, Singer M, Stoltz D, Brown A, Danton J (1982) Buspirone and diazepam in anxiety: a controlled study. J Clin Psychiatry 43: 81-86
41. Roache JD, Griffiths RR (1985) Comparison of triazolam and pentobarbital: performance impairment, subjective effects and abuse liability. J Pharmacol Exp Ther 234: 120-133
42. Roache JD, Griffiths RR (1989) Diazepam and triazolam self-administration in sedative abusers: concordance of subject ratings, performance and drug self-administration. Psychopharmacology 99: 309-315
43. Sellers HM, Schneiderman JF, Romach MK, Kaplan HL, Somer GR (1992) Comparative drug effects and abuse liability of lorazwpam, buspirone, and secobarbital in nondependent subjects. J Clin Psychopharmacol 12: 79-85
44. Sellers EM, Ciraulo DA, DuPont RL, Griffiths RR, Kosten TR, Romach MK, Woody GE (1993) Alprazolam and benzodiazepine dependence. J Clin Psychiatry 54 [suppl. No. 10]: 64-75
45. Steinberg RD (1990) Lack of abuse potential with buspirone (letter). Ann Pharmacother 24: 785
46. Troisi JR H, Critchfield TS, Griffiths RR (1993) Buspirone and lorazepam abuse liability in humans: behavioral effects, subjective effects and choice. Beliav Pharmacol 4: 217-230
47. Wechsler D (1958) The measure and appraisal of adult intelligence. Williams and Wilkins, Baltimore, MD
48. Wheatley D (1982) Buspirone: Multicenter efficacy study. J Clin Psychiatry 43: 92-94
49. Wolf B, Iguchi MY, Griffiths RR (1989) Sedativc/tranquilizer use and abuse in alcoholics currently in outpatient treatment: incidence, pattern and preference. National Institute on Drug Abuse, Research Monograph Series No. 95, pp 376-377
50. Woods JH, Katz JL, Winger G (1992) Benzodiazepines: use, abuse, and consequences. Pharmacol Rev 44: 151-347