메뉴 건너뛰기




Volumn 60, Issue 1, 1996, Pages 121-129

Calphostin C induces tyrosine dephosphorylation/inactivation of protein kinase FA/GSK-3α in a pathway independent of tumor promoter phorbol ester-mediated down-regulation of protein kinase C

Author keywords

Calphostin C; Carcinoma dedifferentiation progression; Down regulation; PKC inhibition; Protein kinase Fa GSK 3

Indexed keywords

CALPHOSTIN C; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C;

EID: 0030053228     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/(sici)1097-4644(19960101)60:1<121::aid-jcb14>3.0.co;2-s     Document Type: Article
Times cited : (11)

References (44)
  • 1
    • 0023691731 scopus 로고
    • Inhibitory effect of a marine-sponge toxin, okadaie acid, on protein phosphatases
    • Bialojan C, Takai A (1988): Inhibitory effect of a marine-sponge toxin, okadaie acid, on protein phosphatases. Biochem J 256:283-290.
    • (1988) Biochem J , vol.256 , pp. 283-290
    • Bialojan, C.1    Takai, A.2
  • 2
    • 0026029808 scopus 로고
    • Activation of protein kinase C decreased phosphorylation of c-jun at sites that negatively regulate its DNA-binding activity
    • Boyle WJ, Smeal T, Defize LHK, Angel P, Woodgett JR, Karin M, Hunter T (1991): Activation of protein kinase C decreased phosphorylation of c-jun at sites that negatively regulate its DNA-binding activity. Cell 64:573-584.
    • (1991) Cell , vol.64 , pp. 573-584
    • Boyle, W.J.1    Smeal, T.2    Defize, L.H.K.3    Angel, P.4    Woodgett, J.R.5    Karin, M.6    Hunter, T.7
  • 3
    • 0021341961 scopus 로고
    • Synthetic tyrosine polymers as substrates and inhibitors of tyrosine-specific protein kinases
    • Braun S, Raymond WE, Racker E (1984): Synthetic tyrosine polymers as substrates and inhibitors of tyrosine-specific protein kinases. J Biol Chem 259:2051-2054.
    • (1984) J Biol Chem , vol.259 , pp. 2051-2054
    • Braun, S.1    Raymond, W.E.2    Racker, E.3
  • 5
    • 0025181418 scopus 로고
    • Okadaic acid: A new probe for the study of cellular regulation
    • Cohen P, Holmes CFB, Tsukitani Y (1990): Okadaic acid: A new probe for the study of cellular regulation. Trends Biochem Sci 15:98-102.
    • (1990) Trends Biochem Sci , vol.15 , pp. 98-102
    • Cohen, P.1    Holmes, C.F.B.2    Tsukitani, Y.3
  • 7
    • 0024233098 scopus 로고
    • Phosphoserine as a recognition determinant for glycogen synthase kinase-3: Phosphorylation of a synthetic peptide base on the G-component of protein phosphatase-1
    • Fiol CJ, Haseman JH, Wang Y, Roach PJ, Roeske RW, Kowulczuk M, DePaoh-Roach AA (1988): Phosphoserine as a recognition determinant for glycogen synthase kinase-3: Phosphorylation of a synthetic peptide base on the G-component of protein phosphatase-1. Arch Biochem Biophys 267:797-802.
    • (1988) Arch Biochem Biophys , vol.267 , pp. 797-802
    • Fiol, C.J.1    Haseman, J.H.2    Wang, Y.3    Roach, P.J.4    Roeske, R.W.5    Kowulczuk, M.6    Depaoh-Roach, A.A.7
  • 8
    • 0026030751 scopus 로고
    • Chemiluminescence detection of proteins from single cells
    • Gillespie PG, Hudspeth AJ (1991): Chemiluminescence detection of proteins from single cells. Proc Natl Acad Sci USA 88:2563-2567.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 2563-2567
    • Gillespie, P.G.1    Hudspeth, A.J.2
  • 9
    • 0025787255 scopus 로고
    • Phosphorylation of bovine neurofilament proteins by protein kinase FA (glycogen synthase kinase 3)
    • Guan R, Khatra BS, Cohlberg JA (1991): Phosphorylation of bovine neurofilament proteins by protein kinase FA (glycogen synthase kinase 3). J Biol Chem 266:8262-8267.
    • (1991) J Biol Chem , vol.266 , pp. 8262-8267
    • Guan, R.1    Khatra, B.S.2    Cohlberg, J.A.3
  • 10
    • 0026487365 scopus 로고
    • Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: Generation of paired helical filament epitopes and neuronal localisation of the kinase
    • Hanger DP, Hughes K, Woodett JR, Brion J-P, Anderton BH (1992): Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: Generation of paired helical filament epitopes and neuronal localisation of the kinase. Neurosci Lett 147:58-62.
    • (1992) Neurosci Lett , vol.147 , pp. 58-62
    • Hanger, D.P.1    Hughes, K.2    Woodett, J.R.3    Brion, J.-P.4    Anderton, B.H.5
  • 11
    • 0019630202 scopus 로고
    • Purification of glycogen synthase kinase 3 from rabbit skeletal muscle. Copurification with the activating factor (FA) of the (Mg-ATP) dependent protein phosphatase
    • Hemmings BA, Yellowlees D, Kernohan JC, Cohen P (1981): Purification of glycogen synthase kinase 3 from rabbit skeletal muscle. Copurification with the activating factor (FA) of the (Mg-ATP) dependent protein phosphatase. Eur J Biochem 119:443-451.
    • (1981) Eur J Biochem , vol.119 , pp. 443-451
    • Hemmings, B.A.1    Yellowlees, D.2    Kernohan, J.C.3    Cohen, P.4
  • 12
    • 0020195709 scopus 로고
    • Phosphorylation of the type-II regulatory subunit of cyclic AMP-dependent protein kinase by glycogen synthase kinase 3 and glycogen synthase kinase 5
    • Hemmings BA, Aitken A, Cohen P, Rymond M, Hofmann F (1982): Phosphorylation of the type-II regulatory subunit of cyclic AMP-dependent protein kinase by glycogen synthase kinase 3 and glycogen synthase kinase 5. Eur J Biochem 127:473-481.
    • (1982) Eur J Biochem , vol.127 , pp. 473-481
    • Hemmings, B.A.1    Aitken, A.2    Cohen, P.3    Rymond, M.4    Hofmann, F.5
  • 13
    • 0027475421 scopus 로고
    • Modulation of the glycogen synthase kinase-3 family by tyrosin phosphorylation
    • Hughes K, Nikolakaki E, Plyte SE, Totty NF, Woodgett JR (1993): Modulation of the glycogen synthase kinase-3 family by tyrosin phosphorylation. EMBO J 12:803-808.
    • (1993) EMBO J , vol.12 , pp. 803-808
    • Hughes, K.1    Nikolakaki, E.2    Plyte, S.E.3    Totty, N.F.4    Woodgett, J.R.5
  • 14
    • 0024550448 scopus 로고
    • Calphostin C (UCN-1028C), a novel microbial compound, is a highly potent and specific inhibitor of protein kinase C
    • Kobayashi E, Nakano H, Morimoto M, Tamaoki T (1989): Calphostin C (UCN-1028C), a novel microbial compound, is a highly potent and specific inhibitor of protein kinase C. Biochem Biophys Res Commun 159:548-553.
    • (1989) Biochem Biophys Res Commun , vol.159 , pp. 548-553
    • Kobayashi, E.1    Nakano, H.2    Morimoto, M.3    Tamaoki, T.4
  • 15
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during assembly of the head of bacteriophage T4
    • Laemmli UK (1970): Cleavage of structural proteins during assembly of the head of bacteriophage T4. Nature 227:680-685.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 16
    • 0029021230 scopus 로고
    • Overexpression of cellular activity and protein level of protein kinase FA/GSK-3α correlates with human thyroid tumor cell dedifferentiation
    • Lee T-T, Ho Y-S, Yu J-S, Yang S-D (1995): Overexpression of cellular activity and protein level of protein kinase FA/GSK-3α correlates with human thyroid tumor cell dedifferentiation. J Cell Biochem 58:1-7.
    • (1995) J Cell Biochem , vol.58 , pp. 1-7
    • Lee, T.-T.1    Ho, Y.-S.2    Yu, J.-S.3    Yang, S.-D.4
  • 17
    • 0024369632 scopus 로고
    • Indentification of 2 protein-kinases taht phosphorykate the neural cell-adhesion molecule, N-CAM
    • Mackie K, Sorkin BC, Nairn AC, Greengard P, Edelman GM, Cunningham BA (1989): Indentification of 2 protein-kinases taht phosphorykate the neural cell-adhesion molecule, N-CAM. J Neurosci 9:1883-1896.
    • (1989) J Neurosci , vol.9 , pp. 1883-1896
    • Mackie, K.1    Sorkin, B.C.2    Nairn, A.C.3    Greengard, P.4    Edelman, G.M.5    Cunningham, B.A.6
  • 19
    • 0023052241 scopus 로고
    • Studies and perspectives of protein kinase C
    • Nishizuka Y (1986): Studies and perspectives of protein kinase C. Science 233:305-312.
    • (1986) Science , vol.233 , pp. 305-312
    • Nishizuka, Y.1
  • 20
    • 0018902461 scopus 로고
    • Use of glutartldehyde as a coupling agent for proteins and peptides
    • Reichlin M (1980): Use of glutartldehyde as a coupling agent for proteins and peptides. Methods Enzymol 70:159-165.
    • (1980) Methods Enzymol , vol.70 , pp. 159-165
    • Reichlin, M.1
  • 21
    • 0028177965 scopus 로고
    • The α-isoform of glycogen synthase kinase-3 from rabbit skeletal muscle is inactivated by p70 S6 kinase or MAP kinase-activated protein kinase-1 in vitro
    • Sutherland C, Cohen P (1994): The α-isoform of glycogen synthase kinase-3 from rabbit skeletal muscle is inactivated by p70 S6 kinase or MAP kinase-activated protein kinase-1 in vitro. FEBS Lett 338:37-42.
    • (1994) FEBS Lett , vol.338 , pp. 37-42
    • Sutherland, C.1    Cohen, P.2
  • 22
    • 0025998841 scopus 로고
    • Use and specificity of staurosporine, UCN-01, and calphostin C as protein kinase inhibitors
    • Tamaoki T (1991): Use and specificity of staurosporine, UCN-01, and calphostin C as protein kinase inhibitors. Methods Enzymol 201:340-347.
    • (1991) Methods Enzymol , vol.201 , pp. 340-347
    • Tamaoki, T.1
  • 23
    • 0022871460 scopus 로고
    • Phosphorylation of nerve growth factor receptor proteins in sympathetic neurons and PC12 cells - In vitro phosphorylation by the cAMP-independent protein kinase FA/GSK-3α
    • Taniuchi M, Johnson EM, Roach PJ, Lawrence JC Jr (1986): Phosphorylation of nerve growth factor receptor proteins in sympathetic neurons and PC12 cells - In vitro phosphorylation by the cAMP-independent protein kinase FA/GSK-3α. J Biol Chem 261-13342-13349.
    • (1986) J Biol Chem , vol.261 , pp. 13342-13349
    • Taniuchi, M.1    Johnson, E.M.2    Roach, P.J.3    Lawrence Jr., J.C.4
  • 24
    • 0019231298 scopus 로고
    • ATP-Mg-dependent protein phosphatase from rabbit muscle. Purification of the activating factor and its regulation as a bifunctional protein also displaying synthase kinase activity
    • Vandenheede JR, Yang S-D, Goris J, Merlevede W (1980): ATP-Mg-dependent protein phosphatase from rabbit muscle. Purification of the activating factor and its regulation as a bifunctional protein also displaying synthase kinase activity. J Biol Chem 255:11768-11774.
    • (1980) J Biol Chem , vol.255 , pp. 11768-11774
    • Vandenheede, J.R.1    Yang, S.-D.2    Goris, J.3    Merlevede, W.4
  • 25
    • 0025286104 scopus 로고
    • Molecular cloning and expression of glycogen synthase kinase-31 Factor A
    • Woodgett JR (1990): Molecular cloning and expression of glycogen synthase kinase-31 Factor A. EMBO J 9:2431-2438.
    • (1990) EMBO J , vol.9 , pp. 2431-2438
    • Woodgett, J.R.1
  • 26
    • 0025761472 scopus 로고
    • A common denominator linking glycogen metabolism, nuclear oncogenes and development
    • Woodgett JR (1991): A common denominator linking glycogen metabolism, nuclear oncogenes and development. Trends Biochem Sci 16:177-181.
    • (1991) Trends Biochem Sci , vol.16 , pp. 177-181
    • Woodgett, J.R.1
  • 27
    • 0022929851 scopus 로고
    • Identification of the ATP : Mg-dependent protein phosphatase activator FA as a myelin basic protein kinase in brain
    • Yang S-D (1986): Identification of the ATP : Mg-dependent protein phosphatase activator FA as a myelin basic protein kinase in brain. J Biol Chem 261:11786-11791.
    • (1986) J Biol Chem , vol.261 , pp. 11786-11791
    • Yang, S.-D.1
  • 28
    • 0011220265 scopus 로고
    • Characteristics and regulation of the ATP : Mg-dependent protein phosphatase activating factor (protein kinase FA)
    • Yang S-D (1991): Characteristics and regulation of the ATP : Mg-dependent protein phosphatase activating factor (protein kinase FA). Adv Prot Phosphatases 6:133-157
    • (1991) Adv Prot Phosphatases , vol.6 , pp. 133-157
    • Yang, S.-D.1
  • 29
    • 0019231301 scopus 로고
    • ATP : Mg-dependent phosphorylase phosphatase from rabbit muscle
    • Yang S-D, Vandenheede JR, Goris J, Merlevede W (1980): ATP : Mg-dependent phosphorylase phosphatase from rabbit muscle. J Biol Chem 255:11759-11767.
    • (1980) J Biol Chem , vol.255 , pp. 11759-11767
    • Yang, S.-D.1    Vandenheede, J.R.2    Goris, J.3    Merlevede, W.4
  • 30
    • 0025909275 scopus 로고
    • Identification and characterization of the ATP : Mg-dependent protein phosphatase activator (FA) as a microtubule protein kinase in the brain
    • Yang S-D, Yu J-S, Lai Y-G (1991): Identification and characterization of the ATP : Mg-dependent protein phosphatase activator (FA) as a microtubule protein kinase in the brain. J Prot Chem 10:171-181.
    • (1991) J Prot Chem , vol.10 , pp. 171-181
    • Yang, S.-D.1    Yu, J.-S.2    Lai, Y.-G.3
  • 31
    • 0026613128 scopus 로고
    • Identification of the ATP : Mg-dependent protein phosphatase activator (FA) as a synapsin I kinase that inhibits crosslinking of synapsin I with brain microtubules
    • Yang S-D, Song J-S, Hsieh Y-T, Liu H-W, Chan W-H (1992a): Identification of the ATP : Mg-dependent protein phosphatase activator (FA) as a synapsin I kinase that inhibits crosslinking of synapsin I with brain microtubules. J Prot Chem 11:539-546
    • (1992) J Prot Chem , vol.11 , pp. 539-546
    • Yang, S.-D.1    Song, J.-S.2    Hsieh, Y.-T.3    Liu, H.-W.4    Chan, W.-H.5
  • 32
    • 0026704178 scopus 로고
    • Cyclic inhibition-potentiation of the crosslinking of synapsin I with brain microtubules by protein kinase FA (an activator of ATP : Mg-dependent protein phosphatase)
    • Yang S-D, Song J-S, Hsieh Y-T, Chan W-H, Liu H-W (1992b): Cyclic inhibition-potentiation of the crosslinking of synapsin I with brain microtubules by protein kinase FA (an activator of ATP : Mg-dependent protein phosphatase). Biochem Biophys Res Commun 184:973-979.
    • (1992) Biochem Biophys Res Commun , vol.184 , pp. 973-979
    • Yang, S.-D.1    Song, J.-S.2    Hsieh, Y.-T.3    Chan, W.-H.4    Liu, H.-W.5
  • 33
    • 0026573207 scopus 로고
    • Dysfunction of insulin mediator protein kinase FA in lymphocytes of patients with NIDDM
    • Yang S-D, Hwang H-S, Ha T-L, Lai Y-G, Jean Y-J (1992c): Dysfunction of insulin mediator protein kinase FA in lymphocytes of patients with NIDDM. Diabetes 41:68-75.
    • (1992) Diabetes , vol.41 , pp. 68-75
    • Yang, S.-D.1    Hwang, H.-S.2    Ha, T.-L.3    Lai, Y.-G.4    Jean, Y.-J.5
  • 34
    • 0027384576 scopus 로고
    • Cyclic modulation of cross-linking interactions of microtubule-associated protein-2 with actin and microtubules by protein kinase FA
    • Yang S-D, Song J-S, Liu H-W, Chan W-H (1993a): Cyclic modulation of cross-linking interactions of microtubule-associated protein-2 with actin and microtubules by protein kinase FA. J Prot Chem 12:393-402.
    • (1993) J Prot Chem , vol.12 , pp. 393-402
    • Yang, S.-D.1    Song, J.-S.2    Liu, H.-W.3    Chan, W.-H.4
  • 35
    • 0027249093 scopus 로고
    • Cyclic modulation of cytoskeleton assembly-disassembly by the ATP : Mg-dependent protein phosphatase activator (kinase FA)
    • Yang S-D, Chan W-H, Liu H-W (1993b): Cyclic modulation of cytoskeleton assembly-disassembly by the ATP : Mg-dependent protein phosphatase activator (kinase FA). Biochem Biophys Res Commun 193:1202-1210.
    • (1993) Biochem Biophys Res Commun , vol.193 , pp. 1202-1210
    • Yang, S.-D.1    Chan, W.-H.2    Liu, H.-W.3
  • 36
  • 37
    • 0028170044 scopus 로고
    • Protein kinase FA/GSK-3α after heparin potentiation phosphorylates tan on sites abnormally phosphorylated in Alzheimer's disease brain
    • Yang S-D, Yu J-S, Shiah S-G, Huang J-J (1994a): Protein kinase FA/GSK-3α after heparin potentiation phosphorylates tan on sites abnormally phosphorylated in Alzheimer's disease brain. J Neurochem 63:1416-1425.
    • (1994) J Neurochem , vol.63 , pp. 1416-1425
    • Yang, S.-D.1    Yu, J.-S.2    Shiah, S.-G.3    Huang, J.-J.4
  • 38
    • 0028652645 scopus 로고
    • Tumor promoter phorbol ester reversibly modulates tyrosine dephosphorylation/inactivation of protein kinase FA/GSK-3α in A431 cells
    • Yang S-D, Yu J-S, Wen Z-D (1994b): Tumor promoter phorbol ester reversibly modulates tyrosine dephosphorylation/inactivation of protein kinase FA/GSK-3α in A431 cells. J Cell Biochem 56:550-558.
    • (1994) J Cell Biochem , vol.56 , pp. 550-558
    • Yang, S.-D.1    Yu, J.-S.2    Wen, Z.-D.3
  • 39
    • 0342510504 scopus 로고
    • Association of protein kinase FA/GSK-3α (a particular member of proline-directed protein kinase family) with human cervical carcinoma dedifferentiation and progression
    • Yang S-D, Yu J-S, Lee T-T, Ni M-H, Yang C-C, Ho Y-S, Tsen T-Z (1995): Association of protein kinase FA/GSK-3α (a particular member of proline-directed protein kinase family) with human cervical carcinoma dedifferentiation and progression. J Cell Biochem 58:474-480.
    • (1995) J Cell Biochem , vol.58 , pp. 474-480
    • Yang, S.-D.1    Yu, J.-S.2    Lee, T.-T.3    Ni, M.-H.4    Yang, C.-C.5    Ho, Y.-S.6    Tsen, T.-Z.7
  • 40
    • 0027314323 scopus 로고
    • Endogenous protein kinases in brain clathrin-coated vesicles
    • Yu J-S, Yang S-D (1993a): Endogenous protein kinases in brain clathrin-coated vesicles. J Neurochem 60:1714-1721.
    • (1993) J Neurochem , vol.60 , pp. 1714-1721
    • Yu, J.-S.1    Yang, S.-D.2
  • 41
    • 0027763481 scopus 로고
    • Immunological and biochemical study on tissue and subcellular distributions of protein kinase FA (an activating factor of ATP : Mg-dependent protein phosphatase). A simplifide and efficient procedure for high quantity purification from brain
    • Yu J-S, Yang S-D (1993b): Immunological and biochemical study on tissue and subcellular distributions of protein kinase FA (an activating factor of ATP : Mg-dependent protein phosphatase). A simplifide and efficient procedure for high quantity purification from brain. J Prot Chem 12:665-674.
    • (1993) J Prot Chem , vol.12 , pp. 665-674
    • Yu, J.-S.1    Yang, S.-D.2
  • 42
    • 0028017996 scopus 로고
    • Tyrosine dephosphorylation and inactivation of protein kinase FA/GSK-3α by genistin in A431 cells
    • Yu J-S, Yang S-D (1994a): Tyrosine dephosphorylation and inactivation of protein kinase FA/GSK-3α by genistin in A431 cells. J Cell Biochem 56;131-141.
    • (1994) J Cell Biochem , vol.56 , pp. 131-141
    • Yu, J.-S.1    Yang, S.-D.2
  • 43
    • 0028302780 scopus 로고
    • Okadaic acid, a serine/threonine phosphatase inhibitor induces tyrosine dephosphorylation/inactivation of protein kinase FA/GSK-3α in A431 cells
    • Yu J-S, Yang S-D (1994b): Okadaic acid, a serine/threonine phosphatase inhibitor induces tyrosine dephosphorylation/inactivation of protein kinase FA/GSK-3α in A431 cells. J Biol Chem 269:14341-14344.
    • (1994) J Biol Chem , vol.269 , pp. 14341-14344
    • Yu, J.-S.1    Yang, S.-D.2
  • 44
    • 0028176874 scopus 로고
    • 97-Pro in brain myelin basic protein. Evidence for Thr-Pro and Ser-Arg-X-X-Ser as consensus sequences motif
    • 97-Pro in brain myelin basic protein. Evidence for Thr-Pro and Ser-Arg-X-X-Ser as consensus sequences motif. J Neurochem 62:1596-1603.
    • (1994) J Neurochem , vol.62 , pp. 1596-1603
    • Yu, J.-S.1    Yang, S.-D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.