The acid metabolite of ZD7114 is a partial agonist of lipolysis mediated by the rat β3-adrenoceptor

European Journal of Pharmacology

Volumn 295, Issue 2-3, 1996, Pages 199-205

  Mayers, Rachel M ^a   Quayle, Simon P ^a   Thompson, Andrew J ^a   Grant, Thomas L ^a   Holloway, Brian R ^a  

^a ASTRAZENECA   (United Kingdom)

Author keywords

Adipocyte; Lipolysis; Partial agonist effect; Rat; White; ZD7114; 3 Adrenoceptor

Indexed keywords

3 ISOPROPYLAMINO 1 (7 METHYL 4 INDANYLOXY) 2 BUTANOL; 4 [2 [(2 HYDROXY 3 PHENOXYPROPYL)AMINO]ETHOXY] N (2 METHOXYETHYL)PHENOXYACETAMIDE; 4 [2 [(2 HYDROXY 3 PHENOXYPROPYL)AMINO]ETHOXY]PHENOXYACETIC ACID; 4 [2 [[2 (3 CHLOROPHENYL) 2 HYDROXYETHYL]AMINO]PROPYL]PHENOXYACETIC ACID; 5 [2 [[2 HYDROXY 3 [4 (1 METHYL 4 TRIFLUOROMETHYL 2 IMIDAZOLYL)PHENOXY]PROPYL]AMINO]ETHOXY]SALICYLAMIDE; BETA 3 ADRENERGIC RECEPTOR; BETA 3 ADRENERGIC RECEPTOR STIMULATING AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; DRUG METABOLITE; FATTY ACID; GLYCEROL; ISOPRENALINE; PARTIAL AGONIST;

ADIPOCYTE; AGONIST; ANIMAL CELL; ARTICLE; COMPETITIVE INHIBITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG ANTAGONISM; EPIDIDYMIS FAT; LIPOLYSIS; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR INTRINSIC ACTIVITY;

EID: 0030053187     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-2999(95)00662-1     Document Type: Article

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