Cellular localization of cystic fibrosis transmembrane regulator protein in piglet and mouse intestine

Cell and Tissue Research

Volumn 283, Issue 2, 1996, Pages 209-213

  Hayden, Ursula L ^a   Carey, Hannah V ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Cystic fibrosis; Cystic fibrosis transmembrane regulator; Intestine; Mucus secretion; Pig mouse

Indexed keywords

TRANSMEMBRANE CONDUCTANCE REGULATOR;

ANIMAL TISSUE; ARTICLE; CELLULAR DISTRIBUTION; GOBLET CELL; INTESTINE; MOUSE; MUCUS SECRETION; NONHUMAN; PRIORITY JOURNAL; SWINE;

ANIMALS; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; IMMUNOENZYME TECHNIQUES; INTESTINAL MUCOSA; MICE; SWINE;

EID: 0030052825     PISSN: 0302766X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004410050531     Document Type: Article

References (18)

1. Ameen NA, Ardito T, Kashgarian M, Marino CR (1995) A unique subset of rat and human intestinal villus cells express the cystic fibrosis transmembrane conductance regulator. Gastroenterology 108:1016-1023
2. Anderson MP, Sheppard DN, Berger HA, Welsh MJ (1992) Chloride channels in the apical membrane of normal and cystic fibrosis airway and intestinal epithelia. Am J Physiol 263 (Lung Cell Mol Physiol 7):L1-L14
3. Berschneider HM, Knowles MR, Azizkhan RG, Boucher RC, Tobey NA, Orlando RC, Powell DW (1988) Altered intestinal chloride transport in cystic fibrosis. FASEB J 2:2625-2629
4. Clarke LL, Grubb BR, Gabriel SE, Smithies O, Koller BH, Boucher RC (1992) Defective epithelial chloride transport in a gene-targeted mouse model of cystic fibrosis. Science 257: 1125-1128
5. Crawford I, Maloney PC, Zeitlin PL, Gugging WB, Hyde SC, Turley H, Gatter KC, Harris A, Higgins CF (1991) Immunocytochemical localization of the cystic fibrosis gene product CFTR. Proc Natl Acad Sci USA 88:9262-9266
6. Englehardt JF, Smith SS, Allen E, Yankaskas JR, Dawson DC, Wilson JM (1994) Coupled secretion of chloride and mucus in skin of Xenopus laevis: possible role for CFTR. Am J Physiol 267 (Cell Physiol 36):C491-C500
7. Fuller CM, Benos DJ (1992) CFTR! Am J Physiol 263 (Cell Physiol 32):C267-C286
8. Fuller CM, Howard MB, Bedwell DM, Fizzel RA, Benos DJ (1992) Antibodies against the cystic fibrosis transmembrane regulator. Am J Physiol 262 (Cell Physiol 31):C396-C404
9. Gaillard D, Ruocco S, Lallemand A, Dalemans W, Hinnrasky J, Puchelle E (1994) Immunohistochemical localization of cystic fibrosis transmembrane conductance regulator in human fetal airway and digestive mucosa. Ped Res 36:137-143
10. Hoogeveen AT, Keulemans J, Willwmsen R, Scholte BJ, Bijman J, Edixhoven MJ, DeJonge HR, Galjaard H (1991) Immunological localization of cystic fibrosis candidate gene products. Exp Cell Res 193:435-437
11. - movement in human colonic epithelial cells (HT29-C1.16E). Biochem J 304:675-678
12. Kuver R, Ramesh N, Lau S, Savard C, Lee SP, Osborne WRA (1994) Constitutive mucin secretion linked to CFTR expression. Biochem Biophys Res Comm 203:1457-1462
13. McCray PB, Reenstra WW, Louie E, Johnson J, Bettencourt JD, Bastacky J (1992) Expression of CFTR and presence of cAMP-mediated fluid secretion in human fetal lung. Am J Physiol (Lung Cell Mol Physiol 6) 262:L472-L481
14. Moughan PJ, Birtles MJ, Cranwell PD, Smith WC, Pedraza (1992) The piglet as a model animal for studying aspects of digestion and absorption in milk-fed human infants. In: Simopoulos AP (ed) Nutritional triggers for health and in disease. World Rev Nutr Diet, vol 67:40-113. Basel, Karger
15. O'Loughlin EV, Hunt DM, Gaskin KJ, Steil D, Bruzuszcak IM, Martin HCO, Bambach C, Smith R (1991) Abnormal epithelial transport in cystic fibrosis jejunum. Am J Physiol 260 (Gastrointest Liver Physiol 23):G758-G763
16. Snouwaert JN, Brigman KK, Latour AM, Malouf NN, Boucher RC, Smithies O, Koller BH (1992) An animal model for cystic fibrosis made by gene targeting. Science 257:1083-1088
17. Strong TV, Boehm K, Collins FS (1994) Localization of cystic fibrosis transmembrane conductance regulator mRNA in the human gastrointestinal tract by in situ hybridization. J Clin Invest 93:347-354
18. Zhou L, Dey CR, Wert SE, Du Vall MD, Frizzell RA, Whitsett JA (1994) Correction of lethal intestinal defect in a mouse model of cystic fibrosis by human CFTR. Science 266:1705-1708