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Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 3, 1996, Pages 1238-1242

P-glycoprotein confers methotrexate resistance in 3T6 cells with deficient carrier-mediated methotrexate uptake

(5) De Graaf, David a Sharma, Rakesh C b Mechetner, Eugene B c Schimke, Robert T b Roninson, Igor B a

a UNIVERSITY OF ILLINOIS AT CHICAGO (United States)

b STANFORD UNIVERSITY (United States)

c Ingenex Inc (United States)

Author keywords

MDR1 gene; membrane transport; methotrexate; multidrug resistance; retroviral vectors

Indexed keywords

GLYCOPROTEIN P; METHOTREXATE; PHLEOMYCIN; PIRITREXIM; VINBLASTINE; VIRUS VECTOR;

ANIMAL CELL; ARTICLE; CANCER RESISTANCE; CELL MEMBRANE TRANSPORT; CONTROLLED STUDY; DIFFUSION; LIPID BILAYER; MOUSE; MULTIDRUG RESISTANCE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL;

ANIMALS; ANTIBODIES, MONOCLONAL; ATP-BINDING CASSETTE TRANSPORTERS; BIOLOGICAL TRANSPORT; CARRIER PROTEINS; CELL LINE; CLONE CELLS; COLONY-FORMING UNITS ASSAY; DRUG RESISTANCE, MULTIPLE; FIBROBLASTS; FLOW CYTOMETRY; FOLIC ACID ANTAGONISTS; HUMANS; KINETICS; METHOTREXATE; MICE; NEOPLASM PROTEINS; P-GLYCOPROTEIN; PHLEOMYCINS; PYRIMIDINES; RECOMBINANT PROTEINS; RETROVIRIDAE; TRANSFECTION; VINBLASTINE;

ANIMALIA; UNIDENTIFIED RETROVIRUS;

EID: 0030052748 PISSN: 00278424 EISSN: None Source Type: Journal
DOI: 10.1073/pnas.93.3.1238 Document Type: Article

Times cited : (108)

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