Synthesis and structural characterisation of analogues of the potassium channel blocker charybdotoxin

Biochimica et Biophysica Acta - Protein Structure and Molecular Enzymology

Volumn 1292, Issue 1, 1996, Pages 31-38

  Dyke, Timothy R ^a   Duggan, Brendan M ^a,d   Pennington, Michael W ^b   Byrnes, Michael E ^b   Kem, William R ^c   Norton, Raymond S ^a  

^a CSIRO   (Australia)

^b Bachem Holding AG   (Switzerland)

^c UNIVERSITY OF FLORIDA   (United States)

^d MONASH UNIVERSITY   (Australia)

Author keywords

Analogues; Helix capping; Neurotoxin; pH titration; Scorpion; Structure function relationship

Indexed keywords

CHARYBDOTOXIN; CHARYBDOTOXIN DERIVATIVE; POTASSIUM CHANNEL; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DOSE RESPONSE; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; ERYTHROCYTE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; LIGHT SCATTERING; NORMAL HUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

SCORPIONES;

EID: 0030051656     PISSN: 01674838     EISSN: None     Source Type: Journal    
DOI: 10.1016/0167-4838(95)00182-4     Document Type: Article

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