Why do exercise-induced ventricular arrhythmias increase with age? Role of M-mode echocardiographic aging changes

Journals of Gerontology - Series A Biological Sciences and Medical Sciences

Volumn 51, Issue 1, 1996, Pages

  Mayuga, Ronaldo ^a   Arrington, Charles T ^a   O'Connor, Frances C ^a   Fleg, Jerome L ^a  

^a NATIONAL INSTITUTE ON AGING   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGED; AGING; ARTICLE; CONTROLLED STUDY; EXERCISE; FEMALE; HEART ATRIUM ENLARGEMENT; HEART LEFT ATRIUM; HEART LEFT VENTRICLE MASS; HEART LEFT VENTRICLE WALL; HEART VENTRICLE ARRHYTHMIA; HUMAN; M MODE ECHOCARDIOGRAPHY; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL;

EID: 0030051544     PISSN: 10795006     EISSN: None     Source Type: Journal    
DOI: 10.1093/gerona/51A.1.M23     Document Type: Article

References (32)

1. Clarke JM, Shelton JR, Hamer J, Taylor S, Venning GR. The rhythm of the normal human heart Lancet 1976;2,508-12.
2. Raftery EB, Cashmann PMM. Long-term recording of the electrocardiogram in a normal population. Postgrad Med J 1976;52(Suppl 7):32-7.
3. Kostis JB, McCrone K, Moreyra AE, et al. Premature ventricular complexes in the absence of identifiable heart disease. Circulation 1981;63:1351-6.
4. Fleg JL, Kennedy HL Cardiac arrhythmias in a healthy elderly population: detection by 24-hour ambulatory electrocardiography. Chest 1982;81:302-7.
5. Froelicher VF, Thomas MM, Pillow C, Lancaster MC. Epidemiologic study of asymptomatic men screened by maximal treadmill testing for latent coronary artery disease. Am J Cardiol 1974;34:770-6.
6. Ekblom B, Hartley LH, Day WC. Occurrence and reproducibility of exercise-induced ventricular ectopy in normal subjects. Am J Cardiol 1979;43:35-40.
7. McHenry PF, Morris SN, Kavalier M, Jordan J. Comparative study of exercise-induced ventricular arrhythmias in normal subjects and patients with documented coronary artery disease. Am J Cardiol 1976,37,609-16
8. Busby M, Shefrin E, Fleg J Prevalence and long-term significance of exercise-induced frequent or repetitive ventricular ectopic beats in apparently healthy volunteers J Am Coll Cardiol 1989;14:1659-65.
9. Gerstenblith G, Frederiksen J, Yin FCP, Fortuin NJ, Lakatta EG. Echocardiography assessment of a normal adult aging population. Circulation 1977;56:273-8.
10. Gardin JM, Henry WL, Savage DD, Ware JH, Burn C, Borer JS. Echocardiographic measurements in normal subjects: evaluation of an adult population without clinically apparent heart disease. J Clin Ultrasound 1979;7:349-447.
11. Messerli FH, Ventura HO, Elizard OJ, Dunn FG. Hypertension and sudden death; increased ventricular ectopic activity in left ventricular hypertrophy. Am J Med 1984;77:18-22.
12. McLenachan J, Henderson E, Morris K, Dargie H. Ventricular arrhythmias in patients with hypertensive left ventricular hypertrophy. N Engl J Med 1987;317.787-92.
13. Levy D, Anderson K, Savage D, Balkus S, Kannel W, Castelli W. Risk of ventricular arrhythmias in left ventricular hypertrophy. The Framingham heart study. Am J Cardiol 1987;60:560-5.
14. Siegal D, Cheitlin M, Black D, Setley D, Hearst N, Hulley S. Risk of ventricular arrhythmias in hypertensive men with left ventricular hypertrophy. Am J Cardiol 1990;65:742-7.
15. Ghali J, Kadakia S, Cooper R, Liao Y. Impact of left ventricular hypertrophy on ventricular arrhythmias in the absence of coronary artery disease J Am Coll Cardiol 1991,17:1277-82.
16. Levy D, Anderson KM, Plehn J, Savage DD, Christionsen JC, Castelli WP. Echocardiographically determined left ventricular structural and functional correlates of complex or frequent ventricular arrhythmias on one-hour ambulatory electrocardiographic monitoring. Am J Cardiol 1987;59:836-40.
17. Bause GS, Fleg JL, Lakatta EG. Exercise-induced arrhythmias in diuretic-treated patients with uncomplicated systemic hypertension. Am J Cardiol 1987;59:874-7.
18. Califf RM, McKinnis RA, McNeer JF, et al. Prognostic value of ventricular arrhythmias associated with treadmill exercise testing in patients studied with cardiac catheterization for suspected ischemic heart disease J Am Coll Cardiol 1983;2:1060-7.
19. Shock NW, Greulich RC, Andres R, et al. Normal human aging: The Baltimore Longitudinal Study of Aging. NIH publ. no. 84-2450. Washington, DC. National Institutes of Health, 1984
20. Feigenbaum H. Echocardiography 4th ed. Philadelphia: Lea and Febriger, 1986.
21. Sahn DJ, DeMaria A, Kisslo J, Weyman A. Recommendations regarding quantuations in M-mode echocardiography: results of a survey of echocardiographic measurements. Circulation 1978;58:1072-83.
22. Devereux RB, Alonso DR, Lutas EM, et al. Echocardiographic assessment of left ventricular hypertrophy: comparison to neuropsy findings. Am J Cardiol 1986;57.450-8.
23. Rose GA, Blackburn H. Cardiovascular survey methods. World Health Organization Monograph. Series No. 56, Geneva. World Health Organization, 1968:137-42
24. Snedecor GW, Cochran WG. Statistical methods. 8th ed. Ames: Iowa State University Press, 1989:215
25. Fleg JL, Lakatta EG. Prevalence and prognosis of exercise-induced nonsustained ventricular tachycardia in apparently healthy volunteers. Am J Cardiol 1984;54.762-4.
26. Elveback L, Lie JT. Continued high prevalence of coronary artery disease at autopsy in Olmstead County, Minnesota, 1950 to 1970 Circulation 1984;70:345-9.
27. Fleg JL, Tzankoff SP, Lakatta EG. Age-related augmentation of plasma catecholamines during dynamic exercise in healthy males. J Appl Physiol 1985;59:1033-9.
28. DeSimone G, Daniels SR, Devereux RB, et al. Left ventricular mass and body size in normotensive children and adults: assessment of allometric relations and impact of overweight. J Am Coll Cardiol 1992;20:1251-60.
29. Gottdiener JS, Brown J, Zoltick J, Fletcher RD. Left ventricular hypertrophy in men with normal blood pressure; relation to exaggerated blood pressure response to exercise. Ann Intern Med 1990;112:161-6.
30. Granath A, Jonsson B, Strandell T. Circulation in healthy old men studied by right heart catheterization at rest and during exercise in supine and sitting positions. Acta Med Scand 1964;176:425-46
31. Rodeheffer RJ, Gerstenblith G, Becker LC, Fleg JL, Weisfeldt ML, Lakatta EG. Exercise cardiac output is maintained with advancing age in healthy human subjects. Cardiac dilatation and increased stroke volume compensate for a diminished heart rate. Circulation 1984;69:203-13.
32. Schulman SP, Lakatta EG, Fleg JL, Lakatta L, Becker LC, Gerstenblith G. Age-related decline in left ventricular filling at rest and exercise. Am J Physiol (Heart Circ Physiol) 1992;263:H1932-8.