Activities of novel aryloxyalkylimidazolines on rat 5-HT2A and 5-HT2C receptors

European Journal of Pharmacology

Volumn 296, Issue 3, 1996, Pages 307-318

  Siegel, Barry W ^a   Freedman, Jules ^a   Vaal, Mark J ^a   Baron, Bruce M ^a  

^a Merrell Dow Research Institute   (United States)

Author keywords

5 HT (5 hydroxytryptamine, serotonin); 5 HT receptor antagonist; 5 HT2A receptor; 5 HT2C receptor; Aryloxyalkylimidazoline; Phosphoinositide hydrolysis

Indexed keywords

(3 CHLOROPHENYL)PIPERAZINE; 4 IODO 2,5 DIMETHOXYAMPHETAMINE; 8 BROMO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL; ALPHA (2,3 DIMETHOXYPHENYL) 1 [2 (4 FLUOROPHENYL)ETHYL] 4 PIPERIDINEMETHANOL; CLOZAPINE; FLUOXETINE; IMIDAZOLINE DERIVATIVE; IODINE 125; KETANSERIN; LYSERGIDE; MDL 100971; MDL 101156; MDL 101600; MDL 102588; MDL 103097; MESULERGINE; RADIOLIGAND; RECEPTOR SUBTYPE; RITANSERIN; SEROTONIN; SEROTONIN 1C RECEPTOR; SEROTONIN 2A RECEPTOR; SEROTONIN AGONIST; SEROTONIN ANTAGONIST; SEROTONIN RECEPTOR AFFECTING AGENT; SPIPERONE; TRAZODONE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING COMPETITION; CELL STRAIN 3T3; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG SELECTIVITY; FIBROBLAST; GENE EXPRESSION; GENETIC TRANSFECTION; HYDROLYSIS; LIGAND BINDING; MOUSE; NONHUMAN; PHOSPHOINOSITIDE METABOLISM; PRIORITY JOURNAL; RAT; STRUCTURE ACTIVITY RELATION;

3T3 CELLS; ANIMALS; BINDING, COMPETITIVE; DOSE-RESPONSE RELATIONSHIP, DRUG; ERGOLINES; IMIDAZOLES; LYSERGIC ACID DIETHYLAMIDE; MICE; PHOSPHATIDYLINOSITOLS; RATS; RECEPTORS, SEROTONIN; SEROTONIN; SEROTONIN AGONISTS; SEROTONIN ANTAGONISTS;

EID: 0030051413     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-2999(95)00711-3     Document Type: Article

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