Chronic (-)-isoprenaline infusion down-regulates β1- and β2-adrenoceptors but does not transregulate muscarinic cholinoceptors in rat heart

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 353, Issue 2, 1996, Pages 213-225

  Matthews, Janine M ^a   Falckh, Patrick H J ^a   Molenaar, Peter ^a   Summers, Roger J ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

1 and 2 adrenoceptors; ( ) Isoprenaline; Autoradiography; Chronotropic response; Homogenate binding; Inotropic response; Muscarinic cholinoceptors; Rat heart

Indexed keywords

5 [2 [[2 HYDROXY 3 [4 (1 METHYL 4 TRIFLUOROMETHYL 2 IMIDAZOLYL)PHENOXY]PROPYL]AMINO]ETHOXY]SALICYLAMIDE; ATROPINE; BETA 1 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR; BETHANECHOL; CYANOPINDOLOL I 125; GUANOSINE TRIPHOSPHATE; ISOPRENALINE; MESSENGER RNA; METHYLSCOPOLAMINE; MUSCARINIC AGENT; MUSCARINIC RECEPTOR; PROPRANOLOL; QUINUCLIDINYL BENZILATE; RADIOLIGAND; RECEPTOR SUBTYPE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; CHRONOTROPISM; CONTROLLED STUDY; DRUG INFUSION; HEART; HEART ATRIUM; HEART RATE; HEART VENTRICLE; INOTROPISM; MALE; NONHUMAN; OSMOTIC MINIPUMP; RAT; RECEPTOR DENSITY; RECEPTOR DOWN REGULATION; REGULATORY MECHANISM; SINUS NODE; SUBCUTANEOUS DRUG ADMINISTRATION; SYSTOLIC BLOOD PRESSURE; TISSUE DISTRIBUTION;

ANIMALS; AUTORADIOGRAPHY; DOWN-REGULATION; HEART; ISOPROTERENOL; MALE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ADRENERGIC, BETA-1; RECEPTORS, ADRENERGIC, BETA-2; RECEPTORS, MUSCARINIC;

EID: 0030050936     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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