Metabolism of the bisphosphonate ester U-91502 in rats

Drug Metabolism and Disposition

Volumn 24, Issue 1, 1996, Pages 65-73

  Slatter, J G ^a   Feenstra, K L ^a   Hauer, M J ^a   Kloosterman, D A ^a   Parton, A H ^a,b   Sanders, P E ^a   Scott, G ^a   Speed, W ^a  

^a PFIZER INC   (United States)

^b Cell Therapeutics Incorporated   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

3 (1 METHYL 6 OXO 4 PHENYL 1H PYRIMIDIN 2 YL) 1,1 PROPANEBISPHOSPHONIC ACID TETRAETHYL ESTER; 3 (1 METHYL 6 OXO 4 PHENYL 1H PYRIMIDIN 2 YL) 1,1 PROPANEBISPHOSPHONIC ACID TRIETHYL ESTER; 3 (5 HYDROXY 1 METHYL 6 OXO 4 PHENYL 1H PYRIMIDIN 2 YL) 1,1 PROPANEBISPHOSPHONIC ACID TETRAETHYL ESTER; BISPHOSPHONIC ACID DERIVATIVE; DRUG METABOLITE; GLUCURONIDE; GLUTATHIONE; OCTYLAMINE; PROADIFEN; PYRIMIDINONE DERIVATIVE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; TAUROCHOLIC ACID; U 91502; U 94532A; U 97294; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG BILE LEVEL; DRUG CONJUGATION; DRUG FECES LEVEL; DRUG GLUCURONIDATION; DRUG METABOLISM; DRUG URINE LEVEL; INTRAVENOUS DRUG ADMINISTRATION; LIVER MICROSOME; MALE; MASS SPECTROMETRY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; RHEUMATOID ARTHRITIS;

ANIMALS; BILE; BIOLOGICAL AVAILABILITY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DIPHOSPHONATES; MALE; MASS SPECTROMETRY; ORGANOPHOSPHORUS COMPOUNDS; RATS; RATS, SPRAGUE-DAWLEY;

ANIMALIA;

EID: 0030050843     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

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