New mutants of Saccharomyces cerevisiae affected in the transport of proteins from the endoplasmic reticulum to the Golgi complex

Genetics

Volumn 142, Issue 2, 1996, Pages 393-406

  Wuestehube, Linda J ^a   Duden, Rainer ^a   Eun, Arlene ^a   Hamamoto, Susan ^a   Korn, Paul ^a   Ram, Rachna ^a   Schekman, Randy ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOHYDRATE; MATING HORMONE ALPHA FACTOR; PROTEIN; SERINE CARBOXYPEPTIDASE;

ALLELE; ARTICLE; ELECTRON MICROSCOPY; ENDOPLASMIC RETICULUM; GENE; GOLGI COMPLEX; IMMUNOBLOTTING; IMMUNOPRECIPITATION; MUTANT; NONHUMAN; PRIORITY JOURNAL; PROTEIN TRANSPORT; SACCHAROMYCES CEREVISIAE; TEMPERATURE SENSITIVITY;

BIOLOGICAL TRANSPORT; ENDOPLASMIC RETICULUM; EPISTASIS, GENETIC; FUNGAL PROTEINS; GENE EXPRESSION REGULATION, FUNGAL; GOLGI APPARATUS; IMMUNOBLOTTING; MEMBRANE PROTEINS; MUTATION; PROTEIN PRECURSORS; SACCHAROMYCES CEREVISIAE;

EID: 0030050828     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (60)

1. BACON, R. A., A. SALMINEN, H. RUOHOLA, P. NOVICK and S. FERRO-NOVICK, 1989 The GTP-binding protein Ypt1p is required for transport in vitro: the Golgi apparatus is defective in ypt1 mutants. J. Cell Biol. 109: 1015-1022.
2. BALLOU, C. E., 1970 A study of the immunochemistry of three yeast mannans. J. Biol. Chem. 245: 1197-1203.
3. BARLOWE, C., L. ORCI, T. YEUNG, M. HOSOBUCHI, S. HAMAMOTO et al., 1994 COP II: a membrane coat formed by Sec proteins that drive vesicle budding from the endoplasmic reticulum. Cell 77: 895-90751.
4. BRAKE, A. J., R S. FULLER and J. THORNER, 1990 Identification of human prohormone-processing endoproteases by homology to the yeast KEX2 gene product, p. 197, in Neuropeptides and Their Receptors, edited by T. W. SCHWARTZ, L. M. HILSTED and J. F. REHFELD. Munksgard, Copenhagen, Denmark.
5. CARLSON, M., and D. BOTSTEIN, 1982 Two differentially regulated mRNAs with different 5′ ends encode secreted and intracellular forms of yeast invertase. Cell 28: 145-154.
6. COSSON, P., and F. LETOURNEUR, 1994 Coatomer interaction with di-lysine endoplasmic reticulum retention motifs. Science 263: 1629-1631.
7. DESHAIES, R. J., and R. SCHEKMAN, 1987 A yeast mutant defective at an early stage in import of secretory protein precursors into the endoplasmic reticulum. J. Cell Biol. 105: 633-645.
8. DUDEN, R., M. HOSOBUCHI, S. HAMAMOTO, M. WINEY, B. BYERS et al., 1994 Yeast β- and β′-coat proteins (COP): two coatomer subunits essential for ER-to-Golgi traffic. J. Biol. Chem 269: 24486-24495.
9. FERRO-NOVICK, S., W. HANSEN, I. SCRAUER and R. SCHEKMAN, 1984 Genes required for completion of proteins into the endoplasmic reticulum in yeast. J. Cell Biol. 98: 44-53.
10. FRANZUSOFF, A., and R. SCHEKMAN, 1989 Functional compartments of the yeast Golgi apparatus are defined by the sec7 mutation. EMBO J. 8: 2695-2702.
11. FRANZUSOFF, A., K. REDDING, J. CROSBY, R. S. FULLER and R. SCHEKMAN, 1991 Localization of components involved in protein transport and processing through the veast Golgi apparatus J. Cell Biol. 112: 27-37.
12. GAYNOR, E. C., S. TE HEESEN, T. R. GRAHAM, M. AEBI and S. D. EMR, 1994 Signal-mediated retrieval of a membrane protein from the Golgi to the ER in yeast. J. Cell Biol. 127: 653-665.
13. GOLDSTEIN, A., and J. O. LAMPEN, 1975 β-D-Fructofuranoside fructohydrolase from yeast. Methods Enzymol. 42: 504-511.
14. HARDWICK, K. G., and H. R. PELHAM, 1992 SED5 encodes a 39-kD integral membrane protein required for vesicular transport between the ER and the Golgi complex. J. Cell Biol. 119: 513-521.
15. HASILIK, A., and W. TANNER, 1978 Carbohydrate moiety of carboxy-peptidase Y and perturbation of its biosynthesis. Eur. J. Biochem. 91: 567-575.
16. HICKE, L., T. YOSHIHISA and R. SCHEKMAN, 1992 Sec23p and a novel 105kDa protein function as a multimeric complex to promote vesicle budding and protein transport from the ER. Mol. Biol. Cell 3: 667-676.
17. HOSOBUCHI, M., T. E. KREIS and R. SCHEKMAN, 1992 SEC21 is a gene required for ER to Golgi protein transport that encodes a subunit of a yeast coatomer. Nature 360: 603-605.
18. ITO, H., Y. FUKUDA, K. MURATA and A. KIMURA, 1983 Transformation of intact yeast cells treated with alkali cations. J. Bacteriol. 153: 163-168.
19. JULIUS, D., R. SCHEKMAN and J. THORNER, 1984 Glycosylation and processing of prepro-α-factor through the veast secretory pathway. Cell 36: 309-318.
20. KAISER, C., and R. SCHEKMAN, 1990 Distinct sets of SEC genes govern transport vesicle formation and fusion early in the secretory pathway. Cell 61: 723-733.
21. KLIONSKY, D. J., P. K. HERMAN and S. D. EMR, 1990 The fungal vacuole: composition, function, and biogenesis. Microbiol. Rev. 54: 266-292.
22. LAEMMLI, U. K., 1970 Cleavage of structural proteins during the assembly of the head of the bacteriophage T4. Nature 227: 680-685.
23. LETOURNEUR, F., E. C. GAYNOR, S. HENNECKE, C. DEMOLLIERE, R. DUDEN et al., 1994 Coatomer is essential for retrieval of dilysine-tagged proteins to the F.R. Cell 79: 1199-1207.
24. LIAN, J. P., and S. FERRO-NOVICK 1993 Bos1p, an integral membrane protein of the endoplasmic reticulum to Golgi transport vesicles is required for their fusion competence. Cell 73: 735-745.
25. LYONS, S., and N NELSON, 1984 An immunological method for detecting gene expression in yeast colonies. Proc. Natl. Acad. Sci. USA 81: 7426-7430.
26. NAKAJIMA, H., A. HIRATA, Y OGAWA, T. YONEHARA, K. YODA et al., 1991 A cytoskeleton-related gene, USO1, is required for intracellular protein transport in Saccharomyces cerevisiae. J. Cell Biol. 113: 245-260.
27. NAKANO, A, and M. MURAMATSU, 1989 A novel GTP-binding protein, Sar1p, is involved in transport from the endoplasmic reticulum to the Golgi apparatus. J. Cell Biol. 109: 2677-2691.
28. 3H] mannose suicide selection. J. Cell Biol. 105: 1587-1594.
29. NEWMAN, A. P., J. SHIM and S. FERRO-NOVICK, 1990 BET1, BOS1, and SEC22 are members of a group of interacting yeast genes required for transport from the endoplasmic reticulum to the Golgi complex. Mol. Cell. Biol 10: 3405-3414.
30. NOVICK, P., C. FIELD and R. SCHEKMAN, 1980 Identification of 23 complementation groups required for post-translational events in the yeast secretory pathway. Cell 21: 205-215.
31. NOVICK, P., S. FERRO and R. SCHEKMAN, 1981 Order of events in the yeast secretory pathway. Cell 25: 461-469.
32. OSSIG, R., C. DASCHER, H. H. TREPTE, H. D. SCHMITT and D. GALLWITZ, 1991 The yeast SLY gene products, suppressors of defects in the essential GTP-binding Ypt1 protein, may act in endoplasmic reticulum-to-Golgi transport. Mol. Cell. Biol. 11: 2980-2993.
33. PALADE, G., 1975 Intracellular aspects of the process of protein synthesis. Science 189: 347-358.
34. PELHAM, H. R. B., 1994 About turn for the COPs? Cell 79: 1125-1127.
35. PERLMAN, D., and H. HALVORSON, 1981 Distinct repressible mRNAs for cytoplasmic and secreted invertase are encoded by a single gene. Cell 25: 525-536.
36. PREUSS, D., J. MULHOLLAND, C. A. KAISER, P. ORLEAN, C. ALBRIGHT et al., 1991 Structure of the veast endoplasmic reticulum: localization of ER proteins using immunofluorescence and electron microscopy. Yeast 7: 891-911.
37. PREUSS, D., J. MULHOLLAND, A. FRANZUSOFF, N SEGEV and D. BOTSTEIN, 1992 Characterization of the Saccharomyces cerevisiae Golgi complex through the cell cycle by immunoelectron microscopy. Mol. Biol. Cell 3: 789-803.
38. PRYER, N. K., L. J. WUESTEHUBE and R. SCHEKMAN, 1992 Vesicle-mediated protein sorting. Annu. Rev. Biochem. 16: 471-516.
39. PRYER, N. K., N. R. SALAMA, R. SCHEKMAN and C. A. KAISER, 1993 Cytosolic Sec13p complex is required for vesicle formation from the endoplasmic reticulum in vitro. J. Cell Biol. 120: 865-875.
40. REDDING, K., C. HOLCOMB and R. FULLER, 1991 Immunolocalization of Kcx2 protease identifies a late Golgi compartment in the yeast Saccharomyces cerevisiae. J. Cell Biol. 113: 527-538.
41. ROBERTS, C. J., G. POHLIG, J. H. ROTHMAN and T. H. STEVENS, 1989 Structure, biosynthesis, and localization of dipeptidyl aminopeptidase B, an integral membrane glycoprotein of the yeast vacuole. J. Cell Biol. 108: 1363-1373.
42. ROBERTS, C. J., C. K. RAYMOND, C. T. YAMASHIRO and T. H. STEVENS, 1991 Methods for studying the yeast vacuole. Methods Enzymol. 194: 644-661.
43. ROBINSON, J. S., T. R. GRAHAM and S. D. EMR, 1991 A putative zinc finger protein, Saccharomyces cerevisiae. Vps18p, affects late Golgi functions required for vacuolar protein sorting and efficient α-factor prohormone maturation. Mol. Cell Biol. 11: 5813-5824.
44. ROSE, M. D., F. WINSTON and P. HIETER, 1989 Methods in Yeast Genetics. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
45. ROTHBLATT, J. A., and D. MEYER, 1986 Secretion in yeast: reconstitution of the translocation and glycosylation of α-factor and invertase in a homologous cell-free system. Cell 44: 619-628.
46. ROTHBLATT, J. A., and R. SCHEKMAN, 1989 A hitchhiker's guide to analysis of the secretory pathway in yeast. Methods Cell Biol. 32: 3-36.
47. ROTHBLATT, J. A., R. J. DESHAIES, S. L. SANDERS, G. DAUM and R. SCHEKMAN, 1989 Multiple genes are required for proper insertion of secretory proteins into the endoplasmic reticulum in yeast. J. Cell Biol. 109: 2641-2652.
48. ROTHMAN, J. E., 1994 Mechanisms of intracellular protein transport. Nature 372: 55-63.
49. ROTHMAN, J. H., C. P. HUNTER, L. A. VALLS and T. H. STEVENS, 1986 Overproduction-induced mislocalization of a yeast vacuolar protein allows isolation of its gene. Proc. Natl. Acad. Sci. USA 83: 3248-3252.
50. SALAMA, N. R., T. YEUNG and R. SCHEKMAN, 1993 The Sec13p complex and reconstitution of vesicle budding from the ER with purified cytosolic proteins. EMBO J. 12: 4073-4082.
51. SCHMITT, H. D., M. PUZICHA and D. GALLWITZ, 1988 Study of a temperature-sensitive mutant of the ras-related YPT1 gene product suggests a role in the regulation of intracellular calcium Cell 53: 635-647.
52. SEGEV, N., J. MULHOLLAND and D. BOTSTEIN, 1988 The yeast GTP-binding YPT1 protein and a mammalian counterpart are associated with the secretion machinery. Cell 52: 915-924.
53. SHEN, S-H., P. CHRETIEN, L. BASTIEN and S. SLILATY, 1991 Primary sequence of the glucanase gene from Oerskovia xanthinolytica. J. Biol. Chem. 266: 1058-1063.
54. SHEKMAN, F., 1991 Getting started with yeast. Methods Enzymol. 194: 3-21.
55. STEVENS, T., B. ESMON and R. SCHEKMAN, 1982 Early stages in the yeast secretory pathway are required for transport of carboxypeptidase Y to the vacuole. Cell 30: 439-448.
56. STIRLING, C. J., J. ROTHBLATT, M. HOSOBUCHI, R. DESHAIES and R. SCHEKMAN, 1992 Protein translocation mutants defective in the insertion of integral membrane proteins into the endoplasmic reticulum. Mol. Biol. Cell 3: 129-142.
57. WATERS, M. G., T. SERAFINI and J. E. ROTHMAN, 1991 'Coatomer': a cytosolic protein complex containing subunits of non-clathrin-coated Goigi transport vesicles. Nature 349: 248-251.
58. WILSBACH, K., and G. PAYNE, 1993 Vpslp, a member of the dynamin GTPase family, is necessary for Golgi membrane protein retention in Saccharomyces cerevisiae. EMBO J. 12: 3049-3059.
59. WRIGHT, R., M. BASSON, I,. D'ARI and J. RINE, 1988 Increased amounts of HMG-CoA reductase induce "karmellae": a proliferation of stacked membrane pairs surrounding the yeast nucleus. J. Cell Biol. 107: 101-114.
60. WUESTEHUBE, L. J., and R. SCHEKMAN, 1993 Selection and screening for yeast secretory mutants. Methods Mol. Genetics 1: 88-106.