Influence of experimental rat model of multiple organ dysfunction on cefepime and amikacin pharmacokinetics

Antimicrobial Agents and Chemotherapy

Volumn 40, Issue 3, 1996, Pages 819-821

  Mimoz, O ^a   Jacolot, A ^b   Padoin, C ^b   Quillard, J ^a   Tod, M ^b   Louchahi, K ^b   Samii, K ^a   Petitjean, O ^b  

^a BICÊTRE HOSPITAL   (France)

^b AVICENNE HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMIKACIN; CEFEPIME; CILASTATIN PLUS IMIPENEM;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG EXCRETION; DRUG HALF LIFE; INTRAPERITONEAL DRUG ADMINISTRATION; LUNG; MULTIPLE ORGAN FAILURE; NONHUMAN; PRIORITY JOURNAL; RAT; TISSUE DISTRIBUTION; URINARY EXCRETION;

EID: 0030050725     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.40.3.819     Document Type: Article

References (17)

1. Alhanese, J., C. Martin, P. Saux, M. N. Mallet, B. Bruguerolles, X. Viviand, P. de Micco, and F. Gouin. 1989. Pharmacocinétique d'un aminoside: la tobramycine, et de deux β-lactamines' l'azlocilline et la céfménoxime chez des patients en ventilation mécanique. Med. Mal. Infect. 19:372-376.
2. Barbhaiya, R. H., S. T. Forgue, W. C. Shyu, E. A. Papp, and K. A. Pittman. 1987 High-pressure liquid Chromatographic analysis of BMY-28142 in plasma and urine. Antimicrob. Agents Chemother 31:51-59.
3. Beckhouse, M. J., I. M. Whyte, P. L. Byth, J. C. Napier, and A. J. Smith. 1988 Altered aminoglycoside pharmacokinetics in the critically ill. Anaesth. Intensive Care 16:418-422.
4. Ellman, H. 1984. Capillary permeability in septic patients. Crit. Care Med. 12:629-633.
5. Goris, R. J. A., W. K. F. Boekholtz, I. P. T. van Bebber, J. K. S. Nuytinck, and P. H. M. Schillings. 1988. Multiple organ failure and sepsis without bacteria. An experimental model. Arch. Surg. 121:897-901.
6. Kieft, H., A. I. M. Hoepelman, C. A. Knupp, A. van Dijk, J. M. Branger, A. Struyvenberg, and J. Verhoef. 1993. Pharmacokinetics of cefepime in patients with the sepsis syndrome. J. Antimicrob. Chemother. 32(Suppl. B): 117-122.
7. Lang, C. H., G. J. Bagby, G. H. Bornside, L. J. Vial, and J. J. Spitzer. 1983. Sustained hypermetabolic sepsis in rats characterization of the model. J. Surg. Res 35:201-210.
8. Mackowiak, P. A. 1989. Influence of fever on pharmacokinetics. Rev. Infect. Dis. 5:804-807
9. Mann, H. J., D. W. Fuchs, R. Awang, F. A. Ndemo, and F. B. Cerra. 1987. Altered aminoglycoside pharmacokinetics in critically ill patients with sepsis. Clin. Pharm 6:148-153.
10. Marik, P. E. 1993 Aminoglycoside volume of distribution and illness severity in critically ill septic patients. Anaesth. Intensive Care 21:172-173.
11. Nix, D. E., D. Goodwin, C. A. Peloquin, D. L. Rotella, and J. Schentag. 1991. Antibiotic tissue penetration and its relevance: models of tissue penetration and their meaning. Antimicrob. Agents Chemother. 35:1947-1952.
12. Oh, G. R., L. M. Mela-Riker, R. E. Bryant, and D. K. Lowe. 1984. A new experimental model of chronic high-output sepsis. Circ. Shock 13:99-104.
13. Tanaka, H., T. E. Dahms, E. Bell, K. S. Naunheim, and L. J. Baudendistel. 1993. Effect of hydroxyethyl starch on alveolar flooding in acute lung injury in dogs. Am. Rev. Respir. Dis. 148:852-859
14. Triginer, C., R. Fernandez, I. Izquiero, and S. Benito. 1989. Gentamicin pharmacokinetic changes related to mechanical ventilation. Drug Intell. Clin Pharm. 138:499-504.
15. Triginer, C., I. Izquiero, R. Fernandez, J. Rello, J. Torrent, S. Benito, and A. Net. 1990. Gentamicin volume of distribution in critically ill septic patients. Intensive Care Med. 16:303-306
16. Van Dalen, R., and T. B. Vree. 1990. Pharmacokinetics of antibiotics in critically ill patients Intensive Care Med. 16(Suppl 3):235-238.
17. Wichterman, K. A., A. E. Baue, and I. H. Chaudry. 1980 Sepsis and septic shock. a review of laboratory models and a proposal J. Surg. Res. 29: 389-201.