Enantioselective Synthesis of (R)- and (S)-α-Aminoacids using (6S)- and (6R)-6-Methyl-morpholine-2,5-dione Derivatives

Tetrahedron Asymmetry

Volumn 7, Issue 1, 1996, Pages 189-196

  Porzi, Gianni ^a   Sandri, Sergio ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID DERIVATIVE;

ARTICLE; DRUG PURIFICATION; DRUG SYNTHESIS; ENANTIOMER; PRIORITY JOURNAL; REACTION ANALYSIS; TECHNIQUE;

EID: 0030050714     PISSN: 09574166     EISSN: None     Source Type: Journal    
DOI: 10.1016/0957-4166(95)00435-1     Document Type: Article

References (14)

1. Williams, R.M., Synthesis of Optically Active α-Amino Acids, Pergamon Press, Oxford, 1989
2. Fitzi, R; Seebach, D.; Tetrahedron 1988,44,5277.
3. Dellaria, J.F.; Santarsiero, B.D., J.Org.Chem, 1989,54,3916 and references therein.
4. Baldwin, J.E.; Lee, V.; Schofield, C.J., Synlett, 1992, 249 and references therein.
5. Williams, R.M.; Im, M.N., J.Am.Chem.Soc. 1991,113,9276.
6. Orena, M.; Porzi, G.; Sandri, S., J.Org.Chem. 1992,57,6532.
7. Orena, M.; Porzi, G.; Sandri, S., J.Chem.Research (S),1993, 318.
8. Porzi, G.; Sandri, S., Tetrahedron Asymmetry 1994,5(3),453 and references therein.
9. D'Arrigo, M.C.; Rossetti, M.; Porzi, G.; Sandri, S., J.Chem.Research (S), 1995, 162; D'Arrigo, M.C.; Porzi, G.; Sandri, S., J.Chem.Research (S), 1995, in press.
10. D'Arrigo, M.C.; Rossetti, M.; Porzi, G.; Sandri, S., J.Chem.Research (S), 1995, 162; D'Arrigo, M.C.; Porzi, G.; Sandri, S., J.Chem.Research (S), 1995, in press.
11. Molecular mechanic calculations have been performed using the PCMODEL 4.0 programme.
12. Gull, R.; Schollkopf, U., Synthesis 1985, 1052 and references therein.
13. Energy calculations have been performed by the MOPAC 6.0 programme.
14. 2O) for the (R)-phenylalanine.