Morphometric analysis of somatotrophs: Effects of age and dietary restriction

Neurobiology of Aging

Volumn 17, Issue 1, 1996, Pages 79-86

  Shimokawa, Isao ^a   Yu, Byung Pal ^b   Higami, Yoshikazu ^a   Ikeda, Takayoshi ^a  

^a NAGASAKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

Aging; Cell number; Dietary restriction; Growth hormone; Immunohistochemistry; Morphometry; Somatotroph

Indexed keywords

GROWTH HORMONE;

AGED; AGING; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOMETRY; DIET RESTRICTION; HISTOMETRY; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SOMATIC CELL;

EID: 0030050668     PISSN: 01974580     EISSN: None     Source Type: Journal    
DOI: 10.1016/0197-4580(95)02028-4     Document Type: Article

References (27)

1. Abribat, T.; Deslauriers, P.; Brauzeau, P.; Gaudreau, P. Alterations of pituitary growth hormone-releasing factor binding sites in aging rats. Endocrinology 128:633-635; 1990.
2. Aherne, W. A.; Dunnil, M. S. Morphometry, London: Edward Arnold Ltd.; 1982.
3. Bertrand, H. A. Modulation of aging in endocrine systems by dietary restriction. In B. P. Yu, ed., Modulation of aging processes by dietary restriction, Boca Raton, FL: CRC Press; 1994:89-120.
4. Billestrup, N.; Swanson, L. W.; Vale, W. Growth hormone-releasing factor stimulates proliferation of somatotrophs in vitro. Proc. Natl. Acad. Sci. USA 83:6854-6857; 1986.
5. Ceda, G. P.; Valenti, G.; Butturini, U.; Hoffman, A. R. Diminished pituitary responsiveness to growth hormone-releasing factor in aging male rats. Endocrinology 118:2109-2114; 1986.
6. Crew, M. D.; Spindler, S. R.; Walford, R. L.; Koizumi, A. Age-related decrease of growth hormone and prolactin gene expression in the mouse pituitary. Endocrinology 121:1251-1255; 1987.
7. de Gennaro Colonna, V.; Zoli, M.; Cocchi, D.; Maggi, A.; Marrama, P.; Agnati, L. F.; Mueller, E. E. Reduced growth hormone releasing factor (GHRF)-like immunoreactivity and GHRF gene expression in the hypothalamus of aged rats. Peptides 10:705-708; 1989.
8. Finkelstein, J. W.; Roffwarg, H. P.; Boyer, R. M.; Kream, J.; Hellman, L. Age-related change in the twenty-four hour spontaneous secretion of growth hormone. J. Clin. Endocrinol. Metab. 35:665-670; 1972.
9. Hsu, S. M.; Raine, L.; Fanger, H. A comparative study of the peroxidase-antiperoxidase method and an avidin-biotin complex method for studying polypeptide hormones with radioimmunoassay antibodies. Am. J. Clin. Pathol. 75:734-738; 1981.
10. Khansari, D. N.; Gustad, T. Effects of long-term, low-dose growth hormone therapy on immune function and life expectancy of mice. Mech. Aging Develop 57:87-100; 1991.
11. Masoro, E. J. Food restriction in rodents: an evaluation of its role in the study of aging. J. Gerontol. 43:59-64; 1988.
12. Maxwell, M. H. Two rapid and simple methods used for the removal of resins from 1.0 m thick epoxy sections. J. Microscopy. 112:253-255; 1978.
13. Merry, B. J.; Holeham, A. M. The endocrine responses to dietary restriction in the rat. In A. D. Woodhead; A. D. Blackett; Hollaender, A., eds. Molecular biology of aging. New York, Plenum Press; 1985:117-142.
14. Morimoto, N.; Kawakami, F.; Makino, S.; Chihara, K.; Hasegawa, M.; Ibata, Y. Age-related changes in growth hormone-releasing factor and somatostatin in the rat hypothalamus. Neuroendocrinology 47:459-464; 1988.
15. Poole, M. C.; Kornegay, III, W. D. Cellular distribution within the rat adenohypophysis: A morphometric study. Anat. Rec. 204:45-53; 1982.
16. Robberecht, P.; Gillard, M.; Waelbroeck, M.; Camus, J.-C.; De Neef, P.; Christophe, J. Decreased stimulation of adenylate cyclase by growth hormone-releasing factor in the anterior pituitary of old rats. Neuroendocrinology 44:429-432; 1986.
17. Rossi, G. L.; Bestetti, G. E.; Galbiati, E.; Muller, E. E.; Cocchi, D. Sexually dimorphic effects of aging on rat somatotropes and lactotropes. J. Gerontol. Biol. Sci. 46:B152-158; 1991.
18. Rudman, D.; Feller, A. G.; Nagraj, H. S.; Gergans, G. A.; Lalitha, P. Y.; Goldberg, A. F.; Schlenker, R. A.; Cohen, L.; Rudman, I. N.; Mattson, D. E. Effects of human growth hormone in men over 60 years old. New Eng. J. Med. 323:1-6; 1990.
19. Shibasaki, T.; Shimuzu, K.; Makahara, M.; Masuda, A.; Ibiki, K.; Demura, H.; Wakabayashi, I.; Ling, N. Age-related changes in plasma growth hormone response to growth hormone-releasing hormones in man. J. Clin. Endocrinol. Metab. 58:212-214; 1984.
20. Shimokawa, I.; Higami, Y. Effect of dietary restriction on pathologic processes. In B. P. Yu, ed., Modulation of aging processes by dietary restriction. Boca Raton, FL: CRC; 1994:247-265.
21. Sonntag, W. E.; Hylka, V. W.; Meites, J. Impaired ability of old male rats to secrete growth hormone in vivo but not in vitro in response to hpGRF (1-44). Endocrinology 113:2305-2307; 1983.
22. Sonntag, W. E.; Steger, R. W.; Forman, L. J.; Meites, J. Decreased pulsatile release of growth hormone in old male rats. Endocrinology 107:1875-1879; 1980.
23. Tannenbaum, G. S.; Martin, J. B. Evidence for an endogenous ultradian rhythm governing growth hormone secretion in the rat. Endocrinology 98:562-570; 1976.
24. Weibel, E. R. Stereological methods vol. 1, Practical methods for biological morphometry. San Diego, CA: Academic Press Inc; 1978.
25. Weindruch, R.; Walford, R. L. The retardation of aging and disease by dietary restriction, Springfield, IL: Charles C. Thomas; 1988.
26. Yu, B. P.; Masoro, E. J.; McMahan, C. A. Nutritional influences on aging of Fischer 344 rats: I. Physical, metabolic, and longevity characteristics. J. Gerontol. 40:657-670; 1985.
27. Yu, B. P. Modulation of aging processes by dietary restriction. Boca Raton, FL: CRC Press, 1994.