Alterations of adenylyl cyclase-linked G proteins in rat liver during aging

American Journal of Physiology - Endocrinology and Metabolism

Volumn 270, Issue 1 33-1, 1996, Pages

  Eakes, Ann T ^b   Hymer, Tazuko K ^b   Rosenthal, Mark J ^b   Moss, Joel ^b   Katz, Michael S ^a  

^a SOUTH TEXAS VETERANS HEALTH CARE SYSTEM   (United States)

^b NONE

Author keywords

adenosine 5' diphosphate ribosylation factor; cholera toxin; pertussis toxin; adrenergic receptor

Indexed keywords

ADENYLATE CYCLASE; BETA ADRENERGIC RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN;

ADENOSINE DIPHOSPHATE RIBOSYLATION; AGING; ANIMAL EXPERIMENT; ARTICLE; BETA ADRENERGIC STIMULATION; ENZYME ACTIVATION; ENZYME ACTIVITY; LIVER METABOLISM; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0030050434     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.1996.270.1.e126     Document Type: Article

References (32)

1. Bokoch, G. M., T. Katada, J. K. Northup, E. L. Hewlett, and A. G. Gilman. Identification of the predominant substrate for ADP-ribosylation by islet activating protein. J. Biol. Chem. 258: 2072-2075, 1983.
2. Brown, H. A., S. Gutowski, C. R. Moomaw, C. Slaughter, and P. C. Sternweis. ADP-ribosylation factor, a small GTP-dependent regulatory protein, stimulates phospholipase D activity. Cell 75: 1137-1144, 1993.
3. i2 α-subunit phosphorylation in intact hepatocytes. Biochem. J. 268: 449-457, 1990.
4. Cockcroft, S., G. M. H. Thomas, A. Fensome, B. Geny, E. Cunningham, I. Gout, I. Hiles, N. F. Totty, O. Truong, and J. J. Hsuan. Phospholipase D: a downstream effector of ARF in granulocytes. Science Wash. DC 263: 523-526, 1994.
5. Dax, E. M., C. L. McNair, J. S. Partilla, T. K. Hymer, S. R. Kohn, R. I. Gregerman, and M. S. Katz. Food restriction (FR) modulates age-related changes in beta-adrenergic stimulated glycogenolysis in hepatocytes of Fischer 344 rats (Abstract). Gerontologist 28: 137A-138A, 1988.
6. Dax, E. M., J. S. Partilla, M. A. Pineyro, and R. I. Gregerman. β-Adrenergic receptors, glueagon receptors, and their relationship to adenylate cyclase in rat liver during aging. Endocrinology 120: 1534-1541, 1987.
7. Fleischer, S., and M. Kervina. Subcellular fractionation of rat liver. Methods Enzymol. 31: 6-41, 1974.
8. Graham, S. M., P. A. Herring, and I. J. Arinze. Age-associated alterations in hepatic β-adrenergic receptor/adenylate cyclase complex. Am. J. Physiol. 253 (Endocrinol. Metab. 16): E277-E282, 1987.
9. s activity by phorbol myristate acetate in rat hepatocytes. Am. J. Physiol. 260 (Cell Physiol. 29): C259-C265, 1991.
10. Jones, D. T., and R. R. Reed. Molecular cloning of five GTP-binding protein cDNA species from rat olfactory neuroepithelium. J. Biol. Chem. 262: 14241-14249, 1987.
11. Kalish, M. I., M. S. Katz, M. A. Piñeyro, and R. I. Gregerman. Epinephrine- and glucagon-sensitive adenylate cyclases of rat liver during aging. Evidence for membrane instability associated with increased enzymatic activity. Biochim. Biophys. Acta 483: 452-466, 1977.
12. Katz, M. S. Food restriction modulates β-adrenergic-sensitive adenylate cyclase in rat liver during aging. Am. J. Physiol. 254 (Endocrinol. Metab. 17): E54-E62, 1988.
13. Katz, M. S., E. M. Dax, and R. I. Gregerman. Beta adrenergic regulation of rat liver glycogenolysis during aging. Exp. Gerontol. 28: 329-340, 1993.
14. Katz, M. S., C. L. McNair, T. K. Hymer, and S. R. Boland. Emergence of beta adrenergic-responsive hepatic glycogenolysis in male rats during post-maturational aging. Biochem. Biophys. Res. Commun. 147: 724-730, 1987.
15. Kristal, B. S., and B. P. Yu. Aging and its modulation by dietary restriction. In: Modulation of Aging Processes by Dietary Restriction, edited by B. P. Yu. Ann Arbor, MI: CRC, 1994, p. 1-35.
16. Linder, M. E., P. Middleton, J. R. Hepler, R. Taussig, A. G. Gilman, and S. M. Mumby. Lipid modifications of G proteins: α subunits are palmitoylated. Proc. Natl. Acad. Sci. USA 90: 3675-3679, 1993.
17. Mader, S., and J. Amos-Landgraf. Age-related decline in beta-adrenergic vasorelaxation and G protein in rat aorta (Abstract). Gerontologist 33: 76-77, 1993.
18. Matsuyama, S., and S. Tsuyama. Mono-ADP-ribosylation in brain: purification and characterization of ADP-ribosyltransferases affecting actin from rat brain. J. Neurochem. 57: 1380-1387, 1991.
19. Moss, J., and M. Vaughan. Isolation of an avian erythrocyte protein possessing ADP-ribosyltransferase activity and capable of activating adenylate cyclase. Proc. Natl. Acad. Sci. USA 75: 3621-3624, 1978.
20. Moss, J., and M. Vaughan. ADP-ribosylation factors: protein activators of cholera toxin. Prog. Nucleic Acid Res. Mol. Biol. 45: 47-65, 1993.
21. 41 subunits of guanine nucleotide-binding regulatory proteins from bovine brain. J. Biol. Chem. 263: 2020-2026, 1988.
22. O'Connor, S. W., P. J. Scarpace, and I. B. Abrass. Age-associated decrease in the catalytic unit activity of rat myocardial adenylate cyclase. Mech. Ageing Dev. 21: 357-363, 1983.
23. i in coupling angiotensin receptors to inhibition of adenylate cyclase in hepatocytes. J. Biol. Chem. 260: 16200-16209, 1985.
24. Price, S. R., C. F. Welsh, R. S. Haun, S. J. Stanley, J. Moss, and M. Vaughan. Effects of phospholipid and GTP on recombinant ADP-ribosylation factors (ARFs). J. Biol. Chem. 267: 17766-17772, 1992.
25. sα by NAD and endogenous ADP-ribosyltransferase. J. Mol. Cell. Cardiol. 26: 251-260, 1994.
26. Ross, E. M., A. C. Hewlett, K. M. Ferguson, and A. G. Gilman. Reconstitution of hormone-sensitive adenylate cyclase activity with resolved components of the enzyme. J. Biol. Chem. 253: 6401-6412, 1978.
27. Ross, E. M., M. E. Maguire, T. W. Sturgill, R. L. Biltonen, and A. G. Gilman. Relationship between the β-adrenergic receptor and adenylate cyclase. Studies of ligand binding and enzyme activity in purified membranes of S49 lymphoma cells. J. Biol. Chem. 252: 5761-5775, 1977.
28. Salomon, Y., C. Londos, and M. Rodbell. A highly sensitive adenylate cyclase assay. Anal. Biochem. 58: 541-548, 1974.
29. Shu, Y., and P. J. Scarpace. Forskolin binding sites and G-protein immunoreactivity in rat hearts during aging. J. Cardiovasc. Pharmacol. 23: 188-193, 1994.
30. Spiegel, A. M., A. Shenker, and L. S. Weinstein. Receptor-effector coupling by G proteins: implications for normal and abnormal signal transduction. Endocr. Rev. 13: 536-565, 1992.
31. Toyoshige, M., S. Okuya, and R. V. Rebois. Choleragen catalyzes ADP-ribosylation of the stimulatory G protein heterotrimer but not its free α-subunit. Biochemistry 33: 4865-4871, 1994.
32. Tsai, S.-C., M. Noda, R. Adamik, J. Moss, and M. Vaughan. Enhancement of choleragen ADP-ribosyltransferase activities by guanyl nucleotides and a 19-kDa membrane protein. Proc. Natl. Acad. Sci. USA 84: 5139-5142, 1987.