Structure of mouse interferon stimulated gene factor 87 (ISGF3γ/ p48) cDNA and chromosomal localization of the gene

Journal of Biochemistry

Volumn 119, Issue 2, 1996, Pages 231-234

  Suhara, Wakako ^a   Yoneyama, Mitsutoshi ^a   Yonekawa, Hiromichi ^a   Fujita, Takashi ^a  

^a TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

Author keywords

Amino acid sequence; Chromosomal localization; Interferon; Interferon stimulated gene factor 3; Reconstitution

Indexed keywords

ALPHA INTERFERON; BETA INTERFERON; COMPLEMENTARY DNA; INTERFERON; INTERFERON STIMULATED GENE FACTOR 3; PROTEIN SUBUNIT; TRANSCRIPTION FACTOR; TYROSINE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; BINDING SITE; CELL NUCLEUS; CELL SURFACE; CHROMOSOMAL LOCALIZATION; CHROMOSOME 14; GENE LOCATION; GENE LOCUS; GENE MAPPING; GENE STRUCTURE; GENETIC LINKAGE; HUMAN; HUMAN CELL; MOLECULAR CLONING; MOUSE; NONHUMAN; PROTEIN DNA BINDING; PROTEIN PHOSPHORYLATION; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CHROMOSOME MAPPING; CLONING, MOLECULAR; DNA, COMPLEMENTARY; DNA-BINDING PROTEINS; HELA CELLS; HUMANS; INTERFERON-STIMULATED GENE FACTOR 3; INTERFERON-STIMULATED GENE FACTOR 3, GAMMA SUBUNIT; LINKAGE (GENETICS); MICE; MOLECULAR SEQUENCE DATA; SEQUENCE HOMOLOGY, AMINO ACID; TRANSCRIPTION FACTORS;

ANIMALIA;

EID: 0030050304     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.jbchem.a021227     Document Type: Article

References (30)

1. DeMaeyer, E. and DeMaeyer-Guignard, J. (1988) Interferons and Other Regulatory Cytokines, John Wiley and Sons, New York
2. Velazquez, L., Fellous, M., Stark, G.R., and Pellegrini, S. (1992) A protein tyrosine kinase in the interferon α/β signaling pathway. Cell 70, 313-322
3. Müller, M., Briscoe, J., Laxton, C., Guschin, D., Ziemiecki, A., Silvennoinen, O., Harpur, A.G., Barbieri, G., Witthuhn, B.A., Schindler, C., Pellegrini, S., Wilks, A.F., Ihle, J.N., Stark, G.R., and Kerr, I.M. (1993) The protein tyrosine kinase JAK1 complements defects in interferon-α/β and -γ signal transduction. Nature 366, 129-135
4. Fu, X.-Y., Schindler, C., Improta, T., Aebersold, R., and Darnell, J.E., Jr. (1992) The proteins of ISGF-3, the interferon α-induced transcriptional activator, define a gene family involved in signal transduction. Proc. Natl. Acad. Sci. USA 89, 7840-7843
5. Schindler, C., Fu, X.-Y., Improta, T., Aebersold, R., and Darnell, J.E., Jr. (1992) Proteins of transcription factor ISGF-3: One gene encodes the 91-and 84-kDa ISGF-3 proteins that are activated by interferon α, Proc. Natl. Acad. Sci. USA 89, 7836-7839
6. Improta, T., Schindler, C., Horvath, C.M., Kerr, I.M., Stark, G.R., and Darnell, J.E., Jr. (1994) Transcription factor ISGF-3 formation requires phosphorylated Stat91 protein, but Stat113 protein is phosphorylated independently of Stat91 protein. Proc. Nat. Acad. Sci. USA 91, 4776-4780
7. Veals, S.A., Schindler, C., Leonard, D., Fu, X.-Y., Aebersold, R., Darnell, J.E., Jr., and Levy, D.E. (1992) Subunit of an alpha-interferon-responsive transcription factor is related to interferon regulatory factor and Myb families of DNA-binding proteins. Mol. Cell. Biol. 12, 3315-3324
8. Fu, X.-Y. (1992) A transcription factor with SH2 and SH3 domains is directly activated by an interferon α-induced cytoplasmic protein tyrosine kinase(s). Cell 70, 323-335
9. Schindler, C., Shuai, K., Prezioso, V.R., and Darnell, J.E., Jr. (1992) Interferon-dependent tyrosine phosphorylation of a latent cytoplasmic transcription factor. Science 257, 809-813
10. Levy, D.E., Kessler, D.S., Pine, R., and Darnell, J.E., Jr. (1989) Cytoplasmic activation of ISGF3, the positive regulator of interferon-α-stimulated transcription, reconstituted in vitro. Genes Dev. 3, 1362-1371
11. Kessler, D.S., Veals, S.A., Fu, X.-Y., and Levy, D.E. (1990) Interferon-α regulates nuclear translocation and DNA-binding affinity of ISGF3, a multimeric transcriptional activator. Genes Dev. 4, 1753-1765
12. Fu, X.-Y., Kessler, D.S., Veals, S.A., Levy, D.E., and Darnell, J.E., Jr. (1990) ISGF3, the transcriptional activator induced by interferon α, consists of multiple interacting polypeptide chains. Proc. Natl. Acad. Sci. USA 87, 8555-8559
13. Miyamoto, M., Fujita, T., Kimura, Y., Maruyama, M., Harada, H., Sudo, Y., Miyata, T., and Taniguchi, T. (1988) Regulated expression of a gene encoding a nuclear factor, IRF-1, that specifically binds to IFN-β gene regulatory elements. Cell 54, 903-913
14. Pine, R. ,Decker, T., Kessler, D.S., Levy, D.E., and Darnell, J.E., Jr. (1990) Purification and cloning of interferon-stimulated gene factor 2 (ISGF2): ISGF2 (IRF-1) can bind to the promoters of both beta interferon- and interferon-stimulated genes but is not a primary transcriptional activator of either. Mol. Cell. Biol. 10, 2448-2457
15. Harada, H., Fujita, T., Miyamoto, M., Kimura, Y., Maruyama, M., Furia, A., Miyata, T., and Taniguchi, T. (1989) Structurally similar but functionally distinct factors, IRF-1 and IRF-2, bind to the same regulatory elements of IFN and IFN-inducible genes. Cell 58, 729-739
16. Driggers, P.H., Ennist, D.L., Gleason, S.L., Mak, W.-H., Marks, M.S., Levi, B.-Z., Flanagan, J.R., Appelle, E., and Ozato, K. (1990) An interferon γ-regulated protein that binds the interferon-inducible enhancer element of major histocompatibility complex class I genes. Proc. Natl. Acad. Sci. USA 87, 3743-3747
17. Eisenbeis, C.F., Singh, H., and Storb, U. (1995) Pip, a novel IRF family member, is a lymphoid-specific, PU.1-dependent transcriptional activator. Genes Dev. 9, 1377-1387
18. Veals, S.A., Maria, T.S., and Levy, D.E. (1993) Two domains of ISGF3γ that mediate protein-DNA and protein-protein interactions during transcription factor assembly contribute to DNA-binding specificity. Mol. Cell. Biol. 13, 196-206
19. Orita, M., Iwahana, H., Kanazawa, H., Hayashi, K., and Sekiya, T. (1989) Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms. Proc. Natl. Acad. Sci. USA 86, 2766-2770
20. Okamoto, M., Ohtsu, H., Miyaki, M., and Yonekawa, H. (1993) No allelic loss at the p53 locus in 1,2-dimethylhydrazine-induced mouse colon tumors: PCR-SSCP analysis with sequence-tagged microsatellite site primers. Carcinogenesis 14, 1483-1486
21. Love, J.M., Knight, A.M., McAleer, M.A., and Todd, J.A. (1990) Towards construction of a high resolution map of the mouse genome using PCR-analysed microsatellites. Nucleic Acids Res. 18, 4123-4130
22. Dietrich, W., Katz, H., Lincoln, E.S., Shin, H.S., Friedman, J., Dracopoli, C.N., and Lander, S.E. (1992) A genetic map of the mouse suitable for typing intraspecific crosses. Genetics 131, 423-447
23. Dietrich, W.F., Miller, J.C., Steen, R.G., Merchant, M., Damron, D., Nahf, R., Gross, A., Joyce, D.C., Wessel, M., Dredge, R.D., Marquis, A., Stein, L.D., Goodman, N., Page, D.C., and Lander, E.S. (1994) A genetic map of the mouse with 4,006 simple sequence length polymorphisms. Nature Genet. 7, 220-225
24. Nadeau, J.H., McCarthy, L., and Cox, R. (1993) Mouse chromosome 14. Mammalian Genome 4, s203-s210
25. Lyon, M.F. and Searle, A.G. (1989) Genetic Variants and Strains of the Laboratory Mouse; Second Edition, p. 387, Oxford University Press, Oxford
26. Bluyssen, H.A.R., Muzaffar, R., Vlieststra, R.J., van der Made, A.C.J., Leung, S., Stark, G.R., Kerr, I.M., Trapman, J., and Levy, D.E. (1995) Combinatorial association and abundance of components of interferon-stimulated gene factor 3 dictate the selectivity of interferon responses. Proc. Natl. Acad. Sci. USA 92, 5645-5649
27. Mizushima, S. and Nagata, S. (1990) pEF-BOS, a powerful mammalian expression vector. Nucleic Acids Res. 18, 5322
28. Harada, H., Willison, K., Sakakibara, J., Miyamoto, M., Fujita, T., and Taniguchi, T. (1990) Absence of the type I IFN system in EC cells: Transcriptional activator (IRF-1) and repressor (IRF-2) genes are developmentally regulated. Cell 63, 303-312
29. Fujita, T., Nolan, G.P., Ghosh, S., and Baltimore, D. (1992) Independent modes of transcriptional activation by the p50 and p65 subunits of NF-xB. Genes Dev. 6, 775-787
30. Kessler, D.S., Levy, D.E., and Darnell, J.E., Jr. (1988) Two interferon-induced nuclear factors bind a single promoter element in interferon-stimulated genes. Proc. Natl. Acad. Sci. USA 85, 8521-8525