Gender differences in local and systemic reactions to inactivated influenza vaccine, established by a meta-analysis of fourteen independent studies

European Journal of Clinical Microbiology and Infectious Diseases

Volumn 15, Issue 1, 1996, Pages 65-70

  Beyer, W E P ^a   Palache, A M ^a   Kerstens, R ^b   Masurel, N ^a  

^a ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

^b Solvay Duphar bv ^*  (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

INFLUENZA VACCINE;

ADULT; ADVERSE DRUG REACTION; AGE; AGED; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DATA BASE; ERYTHEMA; FEMALE; FEVER; HEADACHE; HUMAN; INSOMNIA; MALAISE; MALE; META ANALYSIS; MYALGIA; PRIORITY JOURNAL; PRURITUS; QUESTIONNAIRE; SEX DIFFERENCE;

ADULT; AGE FACTORS; AGED; FEMALE; HUMANS; INFLUENZA VACCINES; MALE; SEX FACTORS; VACCINES, INACTIVATED;

EID: 0030050205     PISSN: 09349723     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF01586187     Document Type: Article

References (24)

1. Merkatz RB, Temple R, Sobel S, Kessler DA, the Working Group on Women in Clinical Trials: Women in clinical trials of new drugs. A change in Food and Drug Administration policy. New England Journal of Medicine 1993, 329: 292-296.
2. Centers for Disease Control: Prevention and control of influenza. Recommendations of the Immunization Practices Advisory Committee (ACIP). Morbidity and Mortality Weekly Report 1991, 40: 1-15.
3. Mostow SR, Eickhoff TC, Chelgren GA, Retailliau HF, Castle M: Studies of inactivated virus vaccines in hospital employees: reactogenicity and absenteeism. Journal of Infectious Diseases 1977, 136, Supplement: 533-538.
4. Masurel N, Laufer J: A one-year study of trivalent influenza vaccines in primed and unprimed volunteers: immunogenicity, clinical reactions and protection. Journal of Hygiene 1984, 92: 263-276.
5. Cate TR, Kasel JA, Couch RB, Six HR, Knight V: Clinical trials of bivalent A/New Jersey/76 - A/Victoria/75 vaccines in the elderly. Journal of Infectious Diseases 1977, 136, Supplement: 518-525.
6. Cate TR, Couch RB, Parker D, Baxter B: Reactogenicity, immunogenicity, and antibody persistence in adults given inactivated influenza virus vaccines - 1978. Reviews of Infectious Diseases 1983, 5: 737-747.
7. Govaert TME, Dinant GJ, Aretz K, Masurel N, Sprenger MJW, Knottnerus JA: Adverse reactions to influenza vaccine in elderly people: randomized double blind placebo controlled trial. British Medical Journal 1993, 307: 988-990.
8. Palache AM, Beyer WER Sprenger MJW, Masurel N, De Jonge S, Vardy A, Charpentier B, Noury J, Van Beek WCA, Borst RJA, Ligthart GJ, Keren G, Rubinstein E: Antibody response after influenza immunization with various vaccine doses: a double-blind, placebo-controlled, multi-centre, dose-response study in elderly nursing-home residents and young adults. Vaccine 1993, 11: 3-9.
9. Palache AM: Influenza subunit vaccine - ten years' experience. European Journal of Clinical Research 1992, 3: 117-138.
10. Dowdle WR, Kendal AP, Noble GR: Influenza viruses. In: Lennette EH, Schmidt NJ (ed): Diagnostic procedures for viral, rickettsial and chlamydial infections. American Public Health Association, Washington, DC, 1979, p. 585-609.
11. Masurel N, Ophof P, De Jong P: Antibody response to immunization with influenza A/USSR/77 (H1N1) virus in young individuals primed or unprimed for A/New Jersey/76 (H1N1) virus. Journal of Hygiene 1981, 87: 201-209.
12. Beyer WEP, Masurel N: Antigenic heterogeneity among influenza A(H3N2) field isolates during an outbreak in 1982/83, estimated by methods of numerical taxonomy. Journal of Hygiene 1985, 94: 97-109.
13. Breslow NE, Day NE: The analysis of case-control studies. Statistical methods in cancer research. Volume 1. International Agency of Research on Cancer, Lyon, 1980, p. 142.
14. Yusuf S, Peto R, Lewis J, Collins R, Sleight P: Beta blockade during and after myocardial infarction: an overview of the randomized trials. Progress in Cardiovascular Diseases 1985, 27: 335-371.
15. Nicholson KG, Tyrrell DAJ, Harrison P, Potter CW, Jennings R, Clark A, Schild GC, Wood JM, Yetts R, Seagroatt V, Huggins A, Anderson SG: Clinical studies of monovalent inactivated whole virus and subunit A/USSR/77 (H1N1) vaccine: serological responses and clinical reactions. Journal of Biological Standardization 1979, 7: 123-136.
16. Jennings R, Potter CW, Massey PMO, Duerden BI, Martin J, Bevan AM: Responses of volunteers to inactivated influenza virus vaccines. Journal of Hygiene 1981, 86: 1-16.
17. Jennings R, Smith TL, Mellersh AR, Clark A, Spencer RC, Potter CW: Antibody response and persistence in volunteers following immunization with varying dosages of a trivalent surface antigen influenza virus vaccine. Journal of Hygiene 1985, 94: 87-95.
18. Goodeve A, Potter CW, Clark A, Jennings R, Schild GC, Yetts R: A graded-dose study of inactivated, surface antigen influenza B vaccine in volunteers: reactogenicity, antibody response and protection to challenge virus infection. Journal of Hygiene 1983, 90: 107-115.
19. Beyer WEP, Teunissen MWE, Diepersloot RJA, Masurel N: Immunogenicity and reactogenicity of two doses of a trivalent influenza split vaccine. An open randomized study in healthy, unprotected, adult volunteers. Journal of Drug Therapy Research 1986, 11: 369-373.
20. Bachmayer H, Liehl E, Schmidt G: Preparation and properties of a novel influenza subunit vaccine. Postgraduate Medical Journal 1976, 52: 360-367.
21. Nathanson CA: Illness and the feminine role: a theoretical review. Social Science and Medicine 1975, 9: 57-62.
22. Verbrugge LM: Females and illness: recent trends in sex differences in the United States. Journal of Health and Social Behavior 1976, 17: 387-403.
23. Nathanson CA: Sex, illness, and medical care. A review of data, theory, and method. Social Science and Medicine 1977, 11: 13-25.
24. Waldron I: Sex differences in illness incidence, prognosis and mortality; issues and evidence. Social Science and Medicine 1983, 17: 1107-1123.