Intimal thickening under shear in a carotid bifurcation - A numerical study

Journal of Biomechanics

Volumn 29, Issue 1, 1996, Pages 1-11

  Lee, D ^a   Chiu, J J ^b  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

Author keywords

Arterial bifurcation flows; Finite volume method; Hemodynamics; Intimal thickening; Wall shear rate

Indexed keywords

COMPUTER SIMULATION; FINITE VOLUME METHOD; HEMODYNAMICS; SHEAR FLOW;

CAROTID BIFURCATION; INTIMAL THICKENING;

BLOOD VESSELS;

ARTERY INTIMA PROLIFERATION; ARTERY WALL; ARTICLE; CAROTID ARTERY BIFURCATION; COMPUTER PROGRAM; GEOMETRY; GROWTH; MATHEMATICAL MODEL; PRIORITY JOURNAL; SHEAR STRESS; SIMULATION;

EID: 0030049991     PISSN: 00219290     EISSN: None     Source Type: Journal    
DOI: 10.1016/0021-9290(95)00024-0     Document Type: Article

References (23)

1. Bharadvaj, B. K. Mabon, R. F. and Giddens, D. P. (1982) Steady flow in a model of the human carotid bifurcation - II, Laser Doppler anemometer measurements. J. Biomechanics 15, 363-378.
2. Caro, C. G., Fitz-Gerald, J. M. and Schroter, R. C. (1971) Atheroma and arterial wall shear observations, correlation and proposal of a shear dependent mass transfer mechanism for atherogenesis. Proc. R. Soc. London Series B 177, 109-159.
3. Chiu, J. J. (1992) Computation of three-dimensional branching flows using a covariant velocity based calculation procedure and zonal grid methods. Ph. D. Thesis, National Cheng Kung University, Tainan, Taiwan, R.O.C.
4. Cornhill, J. F. and Roach M. R. (1976) A quantitative study of the localization of atherosclerotic lesions in the rabbit aorta. Atherosclerosis 23, 489-501.
5. Demirdzic, I. and Peric, M. (1990) Finite volume method for prediction of fluid flow in arbitrarily shaped domains with moving boundaries. Int. J. Numer. Methods Fluids 10, 771-790.
6. Friedman, M. H. (1989) A biologically plausible model of thickening of arterial intima under shear. Arteriosclerosis 9, 511-522.
7. Friedman, M. H., Deters, O. J., Bargeron, C. B., Hutchins, G. M. and Mark, F. F. (1986) Shear-dependent thickening of the human arterial intima. Atherosclerosis 60, 161-171.
8. Fry, D. L. (1969) Certain histological and chemical responses of the vascular interface to acutely induced mechanical stress in the aorta of the dog. Circulation Res. 24, 93-108.
9. Kleinstreuer, C., Nazemi, M. and Archie, J. P. (1991) Hemodynamics analysis of a stenosed carotid bifurcation and its plaque-mitigating design. J. biomech. Engng 113, 330-334.
10. Ku, D. N. and Giddens, D. P. (1987) Laser Doppler anemometer measurements of pulsatile flow in a model carotid bifurcation. J. Biomechanics 20, 407-421
11. Ku, D. N., Giddens, D. P., Christopher, K. Z., Zarins, K. and Glagov, S. (1985) Pulsatile flow and atherosclerosis in the human carotid bifurcation-positive correlation between plaque location and low and oscillating shear stress. Arteriosclerosis 5, 293-302.
12. Lee, D. and Chiu, J. J. (1992a) Covanant velocity based calculation procedure with nonstaggered grids for computation of pulsatile and moving boundary flows. Numer. Heat Trans. Part B 21, 269-286.
13. Lee, D. and Chiu, J. J. (1992b) Computation of physiological bifurcation flows using a patched grid. Comput. Fluids 21, 519-535.
14. Lee, D. and Chiu, J. J. (1992c) A numerical simulation of intimai thickening under shear in arteries. Biorheology 29, 337-351.
15. Lee, D. and Tsuei, Y. M. (1987) LT-GRID, National Science Council Project Report, CS75-0210-0006-04, Taipei, Taiwan, ROC.
16. Nazemi, M. and Kleinstreuer, C., Archie, J. P. and Sorrell, F. Y. (1989) Fluid flow and plaque formation in an aortic bifurcation. J. biomech. Engng 111, 316-324.
17. Perk told, K. and Peter, R. (1990a) Numerical 3D-simulation of pulsatile wall shear stress in an arterial T-bifurcation model. J. biomed. Engng 12, 2-12.
18. Perktold, K., Peter, R. O., Resch, M. and Langs, G. (1991) Pulsatile non-Newtonian blood flow in three-dimensional carotid bifurcation models: a numerical study of flow phenomena under different bifurcation angles. J. biomed. Engng 13, 507-515.
19. Perktold, K. and Resch, M. (1990b) Numerical flow studies in human carotid artery bifurcations: basic discussion of the geometric factor in atherogenesis. J. biomed. Engng 12, 111-123.
20. Rindt, C. C. M., Van Steenhoven, A. A., Janssen, J. D., Reneman, R. S. and Segal, A. (1990) A numerical analysis of steady flow in a 3-D model of the carotid artery bifurcation. J. Biomechanics 23, 461-473.
21. Rindt, C. C. M., Van Steenhoven, A. A. and Reneman, R. S. (1988) An experimental analysis of the flow field in a three-dimensional model of the human carotid artery bifurcation. J. Biomechanics 21, 985-991.
22. Sinzinger H., Silberbauer K. and Auerswald, W. (1980) Quantitative investigation of sudanophilic lesions around the aortic ostia of human fetuses, newborn and children. Blood Vessels 17, 44-52.
23. Zarins, C. K., Giddens, D. P., Bharadvaj, B. K., Sottiurai, V. S. and Mabon, R. F. (1983) Carotid bifurcation atherosclerosis-quantitative correlation of plaque localization with flow velocity profiles and wall shear stress. Circulation Res. 53, 502-514.