메뉴 건너뛰기




Volumn 156, Issue 1, 1996, Pages 136-145

Insertional mutagenesis affecting programmed cell death leads to thymic hyperplasia and altered thymopoiesis

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; T LYMPHOCYTE RECEPTOR;

EID: 0030049720     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (9)

References (59)
  • 1
    • 78651141386 scopus 로고
    • The autonomous behavior of normal thymus grafts
    • Metcalf, D. 1963. The autonomous behavior of normal thymus grafts. Aust. J. Exp. Biol. Med. Sci. 41:437.
    • (1963) Aust. J. Exp. Biol. Med. Sci. , vol.41 , pp. 437
    • Metcalf, D.1
  • 2
    • 0013888081 scopus 로고
    • Autoradiographic analysis of lymphopoiesis and lymphocyte migration in mice bearing multiple thymus grafts
    • Matsuyama, M., M. Wiadrowski, and D. Metcalf. 1966 Autoradiographic analysis of lymphopoiesis and lymphocyte migration in mice bearing multiple thymus grafts. J. Exp. Med. 123:559.
    • (1966) J. Exp. Med. , vol.123 , pp. 559
    • Matsuyama, M.1    Wiadrowski, M.2    Metcalf, D.3
  • 3
    • 0024332461 scopus 로고
    • Peripheral T lymphocytes: Expansion potential and homeostatic regulation of pool size and CD4/CD8 ratio in vivo
    • Rocha, B., N. Dautigny, and P. Pereira. 1989. Peripheral T lymphocytes: expansion potential and homeostatic regulation of pool size and CD4/CD8 ratio in vivo. Eur J. Immunol. 19:905
    • (1989) Eur J. Immunol. , vol.19 , pp. 905
    • Rocha, B.1    Dautigny, N.2    Pereira, P.3
  • 4
    • 0025150803 scopus 로고
    • Accumulation of bromodeoxyuridine-labeled cells in central and peripheral lymphoid organs, minimal estimates of production and turnover rates of mature lymphocytes
    • Rocha, B , C Penit, C Baron, F. Vasseur, N. Dautigny, and A A. Freitas. 1990. Accumulation of bromodeoxyuridine-labeled cells in central and peripheral lymphoid organs, minimal estimates of production and turnover rates of mature lymphocytes. Eur J Immunol 20.1697
    • (1990) Eur J Immunol , vol.20 , pp. 1697
    • Rocha, B.1    Penit, C.2    Baron, C.3    Vasseur, F.4    Dautigny, N.5    Freitas, A.A.6
  • 5
    • 0027465502 scopus 로고
    • Glucocorticoid-mediated control of the activation and clonal deletion of peripheral T cells in vivo
    • Gonzalo, J. A , A Gonzalez-Garcia, C. Martinez-A., and G. Kroemer. 1993. Glucocorticoid-mediated control of the activation and clonal deletion of peripheral T cells in vivo. J Exp. Med 177.1239
    • (1993) J Exp. Med , vol.177 , pp. 1239
    • Gonzalo, J.A.1    Gonzalez-Garcia, A.2    Martinez-A., C.3    Kroemer, G.4
  • 7
    • 0029065488 scopus 로고
    • Crucial role of the pre-T-cell receptor α gene in development of αβ but not γδ T-cells
    • Fehling, H. J., A. Krotkova, C Saint-Ruf, and H von Boehmer. 1995. Crucial role of the pre-T-cell receptor α gene in development of αβ but not γδ T-cells Nature 375:795.
    • (1995) Nature , vol.375 , pp. 795
    • Fehling, H.J.1    Krotkova, A.2    Saint-Ruf, C.3    Von Boehmer, H.4
  • 9
    • 0023404246 scopus 로고
    • Unexpected thymic hyperplasia in transgenic mice harboring a neuronal promoter fused with simian virus 40 large T antigen
    • Botteri, F., H. van der Putten, D F Wong, C. A. Sauvage, and R. M Evans 1987 Unexpected thymic hyperplasia in transgenic mice harboring a neuronal promoter fused with simian virus 40 large T antigen. Mol Cell. Biol 7:3178
    • (1987) Mol Cell. Biol , vol.7 , pp. 3178
    • Botteri, F.1    Van Der Putten, H.2    Wong, D.F.3    Sauvage, C.A.4    Evans, R.M.5
  • 11
    • 0026439404 scopus 로고
    • Transgenes encoding mutant simian virus 40 large T antigens unmask phenotypic and functional constraints in thymic epithelial cells
    • Moll, J , H. Eibel, F Botteri, G Sansig, C. Regnier, and H. van der Putten. 1992. Transgenes encoding mutant simian virus 40 large T antigens unmask phenotypic and functional constraints in thymic epithelial cells. Oncogene 7:2175
    • (1992) Oncogene , vol.7 , pp. 2175
    • Moll, J.1    Eibel, H.2    Botteri, F.3    Sansig, G.4    Regnier, C.5    Van Der Putten, H.6
  • 16
    • 0026458601 scopus 로고
    • Thymic selection: A matter of life and death
    • Von Boehmer, H. 1992. Thymic selection: a matter of life and death Immunol. Today 13:454
    • (1992) Immunol. Today , vol.13 , pp. 454
    • Von Boehmer, H.1
  • 18
    • 0021187030 scopus 로고
    • Intrathymic lymphopoiesis, stromal cell-associated proliferation of T cells is independent of lymphocyte genotype
    • Kyewski, B. A., M. Travis, and H S Kaplan 1984 Intrathymic lymphopoiesis, stromal cell-associated proliferation of T cells is independent of lymphocyte genotype. J Immunol. 133:1111.
    • (1984) J Immunol. , vol.133 , pp. 1111
    • Kyewski, B.A.1    Travis, M.2    Kaplan, H.S.3
  • 21
    • 0021052516 scopus 로고
    • Characterization of the murine T cell surface molecule, designated L3T4, identified by monoclonal antibody GK 1.5: Similarity of L3T4 to the human Leu3/T4 molecule
    • Dialynas, D. P., Z. S. Quan, K. A. Wall, A. Pierres, J. Quintans, M. R Loken, M. Pierres, and F. W. Fitch. 1983. Characterization of the murine T cell surface molecule, designated L3T4, identified by monoclonal antibody GK 1.5: similarity of L3T4 to the human Leu3/T4 molecule J. Immunol. 131:2445.
    • (1983) J. Immunol. , vol.131 , pp. 2445
    • Dialynas, D.P.1    Quan, Z.S.2    Wall, K.A.3    Pierres, A.4    Quintans, J.5    Loken, M.R.6    Pierres, M.7    Fitch, F.W.8
  • 22
    • 0018652555 scopus 로고
    • Xenogeneic monoclonal antibodies to mouse lymphoid differentiation antigens
    • Ledbetter, J. A., and L. A. Herzenberg. 1979. Xenogeneic monoclonal antibodies to mouse lymphoid differentiation antigens. Immunol Rev. 47:63.
    • (1979) Immunol Rev. , vol.47 , pp. 63
    • Ledbetter, J.A.1    Herzenberg, L.A.2
  • 23
    • 0020029462 scopus 로고
    • Genetic characterization of a polymorphic murine cell-surface glycoprotein
    • Lesley, J., and I S. Trowbridge. 1982. Genetic characterization of a polymorphic murine cell-surface glycoprotein. Immunogenetics 15:313
    • (1982) Immunogenetics , vol.15 , pp. 313
    • Lesley, J.1    Trowbridge, I.S.2
  • 24
    • 0018082103 scopus 로고
    • Monoclonal xenogeneic antibodies to murine cell surface antigens: Identification of novel leukocyte differentiation antigens
    • Springer, T. A., G Galfre, D. S. Secher, and C. Milstein. 1978. Monoclonal xenogeneic antibodies to murine cell surface antigens: identification of novel leukocyte differentiation antigens. Eur. J. Immunol. 8:539.
    • (1978) Eur. J. Immunol. , vol.8 , pp. 539
    • Springer, T.A.1    Galfre, G.2    Secher, D.S.3    Milstein, C.4
  • 25
    • 0018941246 scopus 로고
    • Specific in vivo localization of monoclonal antibodies directed against the Thy-1.1 antigen
    • Houston, L. L., R. C. Nowinski, and I. D Bernstein. 1980. Specific in vivo localization of monoclonal antibodies directed against the Thy-1.1 antigen. J. Immunol. 125:837.
    • (1980) J. Immunol. , vol.125 , pp. 837
    • Houston, L.L.1    Nowinski, R.C.2    Bernstein, I.D.3
  • 26
    • 0024535530 scopus 로고
    • Characterization of a monoclonal antibody which detects alt murine αβ T cell receptors
    • Kubo, R. T., W. Born, J. W Kappler, P Marrack, and M. Pigeon. 1989 Characterization of a monoclonal antibody which detects alt murine αβ T cell receptors. J. Immunol 142:2736.
    • (1989) J. Immunol , vol.142 , pp. 2736
    • Kubo, R.T.1    Born, W.2    Kappler, J.W.3    Marrack, P.4    Pigeon, M.5
  • 27
    • 0024818822 scopus 로고
    • Intraepithelial lymphocytes: Anatomical site, not T cell receptor form, dictates phenotype and function
    • Goodman, T., and L. Lefrancois. 1989. Intraepithelial lymphocytes: anatomical site, not T cell receptor form, dictates phenotype and function. J. Exp. Med. 170:1569.
    • (1989) J. Exp. Med. , vol.170 , pp. 1569
    • Goodman, T.1    Lefrancois, L.2
  • 28
    • 0019474723 scopus 로고
    • A monoclonal antibody that recognizes B cells and B cell precursors in mice
    • Coffman, R., and I. L. Weissman. 1981 A monoclonal antibody that recognizes B cells and B cell precursors in mice. J. Exp. Med. 153:269.
    • (1981) J. Exp. Med. , vol.153 , pp. 269
    • Coffman, R.1    Weissman, I.L.2
  • 29
    • 0024270586 scopus 로고
    • Monoclonal antibodies reactive with subsets of mouse and human thymic epithelial cells
    • Rouse, R. V., L M Bolin, J. R. Bender, and B. A. Kyewski. 1988. Monoclonal antibodies reactive with subsets of mouse and human thymic epithelial cells J. Histochem. Cytochem. 36:1511.
    • (1988) J. Histochem. Cytochem. , vol.36 , pp. 1511
    • Rouse, R.V.1    Bolin, L.M.2    Bender, J.R.3    Kyewski, B.A.4
  • 30
    • 0022511898 scopus 로고
    • Langerhans cells, veiled cells. and interdigitating cells in the mouse recognized by a monoclonal antibody
    • Kraal, G., M. Breel, M. Janse, and G. Bruin 1986. Langerhans cells, veiled cells. and interdigitating cells in the mouse recognized by a monoclonal antibody J Exp. Med. 163:981
    • (1986) J Exp. Med. , vol.163 , pp. 981
    • Kraal, G.1    Breel, M.2    Janse, M.3    Bruin, G.4
  • 31
    • 0023513613 scopus 로고
    • Dendritic cells of the mouse recognized by two monoclonal antibodies
    • Breel M , R. E Mebius, and G. Kraal. 1987. Dendritic cells of the mouse recognized by two monoclonal antibodies. Eur J. Immunol. 17.1555.
    • (1987) Eur J. Immunol. , vol.17 , pp. 1555
    • Breel, M.1    Mebius, R.E.2    Kraal, G.3
  • 32
    • 0021256517 scopus 로고
    • Monoclonal antibodies to stromal cell types of the mouse thymus
    • Vliet, E., M. Melts, and W. van Ewijk. 1984. Monoclonal antibodies to stromal cell types of the mouse thymus Eur J. Immunol 14:524.
    • (1984) Eur J. Immunol , vol.14 , pp. 524
    • Vliet, E.1    Melts, M.2    Van Ewijk, W.3
  • 33
    • 0019784850 scopus 로고
    • F4/80, a monoclonal antibody directed specifically against the mouse macrophage
    • Austyn, J M., and S Gordon. 1981 F4/80, a monoclonal antibody directed specifically against the mouse macrophage. Eur J Immunol. 11 805.
    • (1981) Eur J Immunol. , vol.11 , pp. 805
    • Austyn, J.M.1    Gordon, S.2
  • 34
    • 0022654204 scopus 로고
    • Differential expression of Ia and Ia-associated invariant chain in mouse tissue after in vivo treatment with IFN-γ
    • Momburg, F , N. Koch, P. Moller, G Moldenhauer, G. W. Butcher, and G. J. Hammerling. 1986 Differential expression of Ia and Ia-associated invariant chain in mouse tissue after in vivo treatment with IFN-γ. J. Immunol. 136:940.
    • (1986) J. Immunol. , vol.136 , pp. 940
    • Momburg, F.1    Koch, N.2    Moller, P.3    Moldenhauer, G.4    Butcher, G.W.5    Hammerling, G.J.6
  • 35
    • 0023253951 scopus 로고
    • Phenotype of stromal cell-associated thymocytes in situ is compatible with selection of the T cell repertoire at an "immature" stage of thymic T cell differentiation
    • Kyewski, B. A., F. Momburg, and V. Schirrmacher 1987. Phenotype of stromal cell-associated thymocytes in situ is compatible with selection of the T cell repertoire at an "immature" stage of thymic T cell differentiation Eur J. Immunol. 17.961.
    • (1987) Eur J. Immunol. , vol.17 , pp. 961
    • Kyewski, B.A.1    Momburg, F.2    Schirrmacher, V.3
  • 36
    • 0025933951 scopus 로고
    • Kinetics and efficacy of positive selection in the thymus of normal and T cell receptor transgenic mice
    • Huesmann, M., B. Scott, P. Kisielow, and H. von Boehmer. 1991. Kinetics and efficacy of positive selection in the thymus of normal and T cell receptor transgenic mice. Cell 66.533.
    • (1991) Cell , vol.66 , pp. 533
    • Huesmann, M.1    Scott, B.2    Kisielow, P.3    Von Boehmer, H.4
  • 37
    • 0023250868 scopus 로고
    • Seeding of thymic microenvironments defined by distinct thymocyte-stromal cell interactions is developmemally controlled
    • Kyewski, B. A. 1987. Seeding of thymic microenvironments defined by distinct thymocyte-stromal cell interactions is developmemally controlled. J Exp. Med. 166.520
    • (1987) J Exp. Med. , vol.166 , pp. 520
    • Kyewski, B.A.1
  • 39
    • 0025726216 scopus 로고
    • A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry
    • Nicoletti, I., G. Migliorati, M. C. Pagliacci, F Grignani, and C Riccardi. 1991 A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J Immunol. Methods 139:271.
    • (1991) J Immunol. Methods , vol.139 , pp. 271
    • Nicoletti, I.1    Migliorati, G.2    Pagliacci, M.C.3    Grignani, F.4    Riccardi, C.5
  • 40
    • 0018833714 scopus 로고
    • Thymus cell migration, quantitative aspects of cell traffic from thymus to periphery in mice
    • Scollay, R. G , E C. Butcher, and I. L. Weissman. 1980 Thymus cell migration, quantitative aspects of cell traffic from thymus to periphery in mice Eur J. Immunol. 10:210
    • (1980) Eur J. Immunol. , vol.10 , pp. 210
    • Scollay, R.G.1    Butcher, E.C.2    Weissman, I.L.3
  • 41
    • 0028988659 scopus 로고
    • Thymic emigration, conveyor belts or lucky dips
    • Scollay, R., and D. I. Godfrey. 1995. Thymic emigration, conveyor belts or lucky dips. Immunol. Today 16:268
    • (1995) Immunol. Today , vol.16 , pp. 268
    • Scollay, R.1    Godfrey, D.I.2
  • 44
    • 0026030196 scopus 로고
    • 2+ thymocytes as post-selection intermediates leading to mature T cells
    • 2+ thymocytes as post-selection intermediates leading to mature T cells J Exp Med. 173:323.
    • (1991) J Exp Med. , vol.173 , pp. 323
    • Shortman, K.1    Vremec, D.2    Egerton, M.3
  • 46
    • 0028057579 scopus 로고
    • Generation of mature T cell populations in the thymus CD3 or CD8 down-regulation occurs at different stages of thymocyte differentiation
    • Maradon, G., and B. Rocha 1994. Generation of mature T cell populations in the thymus CD3 or CD8 down-regulation occurs at different stages of thymocyte differentiation Eur. J. Immunol. 24:196.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 196
    • Maradon, G.1    Rocha, B.2
  • 48
    • 0022911175 scopus 로고
    • Thymic nurse cells: Possible sites of T-cell selection
    • Kyewski, B. A. 1986. Thymic nurse cells: possible sites of T-cell selection. Immunol. Today 7:374.
    • (1986) Immunol. Today , vol.7 , pp. 374
    • Kyewski, B.A.1
  • 49
    • 0025786164 scopus 로고
    • Bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship
    • Strasser, A., A W Harris, and S Cory. 1991. Bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship. Cell 67.889.
    • (1991) Cell , vol.67 , pp. 889
    • Strasser, A.1    Harris, A.W.2    Cory, S.3
  • 50
    • 0025751550 scopus 로고
    • Bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes
    • Sentman, C. L., J R. Shutter, D. Hockenberry, O. Kanagawa, and S J. Korsmeyer 1991. Bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes. Cell 67:879
    • (1991) Cell , vol.67 , pp. 879
    • Sentman, C.L.1    Shutter, J.R.2    Hockenberry, D.3    Kanagawa, O.4    Korsmeyer, S.J.5
  • 51
    • 0027497115 scopus 로고
    • Expression of a Pim-1 transgene accelerates lymphoproliferation and inhibits apoptosis in lpr/lpr mice
    • Möroy, T., A Grzeschiczek, S Petzold, and K-U Hartmann. 1993 Expression of a Pim-1 transgene accelerates lymphoproliferation and inhibits apoptosis in lpr/lpr mice. Proc. Natl Acad. Sci. USA 90:10734.
    • (1993) Proc. Natl Acad. Sci. USA , vol.90 , pp. 10734
    • Möroy, T.1    Grzeschiczek, A.2    Petzold, S.3    Hartmann, K.-U.4
  • 53
    • 0023254139 scopus 로고
    • T cell antigen receptor expression in athymic (nu/nu) mice. Evidence for an oligoclonal β-chain receptor
    • MacDonald, H. R , R. K. Lees, C. Bron, B. Sordat, and G. Miescher. 1987 T cell antigen receptor expression in athymic (nu/nu) mice. Evidence for an oligoclonal β-chain receptor. J. Exp. Med. 166:195
    • (1987) J. Exp. Med. , vol.166 , pp. 195
    • MacDonald, H.R.1    Lees, R.K.2    Bron, C.3    Sordat, B.4    Miescher, G.5
  • 54
    • 0028230798 scopus 로고
    • Early progression of thymocytes along the CD4/CD8 developmental pathway is regulated by a subset of thymic epithelial cells expressing transforming growth factor β
    • Takaham, Y , J. J. Letterio, H. Suzuki, A. G. Farr, and A. Singer. 1994. Early progression of thymocytes along the CD4/CD8 developmental pathway is regulated by a subset of thymic epithelial cells expressing transforming growth factor β. J. Exp. Med. 179:1495.
    • (1994) J. Exp. Med. , vol.179 , pp. 1495
    • Takaham, Y.1    Letterio, J.J.2    Suzuki, H.3    Farr, A.G.4    Singer, A.5
  • 55
    • 0026008166 scopus 로고
    • Aminopeptidase a activity of the murine B-lymphocyte differentiation antigen BP-1/6C3
    • Wu, Q , L. Li, M. D. Cooper, M Pierres, and J. P. Gorvel 1991. Aminopeptidase A activity of the murine B-lymphocyte differentiation antigen BP-1/6C3. Proc. Natl. Acad. Sci. USA 88.676.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 676
    • Wu, Q.1    Li, L.2    Cooper, M.D.3    Pierres, M.4    Gorvel, J.P.5
  • 56
    • 0026688409 scopus 로고
    • Inefficient positive selection of T cells directed by hematopoietic cells
    • Bix, M., and D. Raulet 1992. Inefficient positive selection of T cells directed by hematopoietic cells. Nature 359:330.
    • (1992) Nature , vol.359 , pp. 330
    • Bix, M.1    Raulet, D.2
  • 59
    • 0028349103 scopus 로고
    • Differential contribution of thymic outputs and peripheral expansion in the development of peripheral T cell pools
    • Modigliani, Y , G. Coutinho, O. Burlen-Defrauoux, A. Coutinho, and A. Bandeira. 1994 Differential contribution of thymic outputs and peripheral expansion in the development of peripheral T cell pools Eur. J. Immunol. 24: 1223.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 1223
    • Modigliani, Y.1    Coutinho, G.2    Burlen-Defrauoux, O.3    Coutinho, A.4    Bandeira, A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.