Lack of effect of zinc supplementation on antipyrine clearance in alcoholic liver disease

European Journal of Clinical Pharmacology

Volumn 49, Issue 5, 1996, Pages 397-399

  Gronbaek K ^a   Friis, H ^b   Feldman, M ^a   Sonne, J ^a   Andreasen, P B ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Alcoholic liver disease; Antipyrine clearance; Liver cirrhosis; Zinc supplementation

Indexed keywords

PHENAZONE; ZINC;

ADULT; AGED; ALCOHOL LIVER CIRRHOSIS; ALCOHOL LIVER DISEASE; ARTICLE; CLINICAL ARTICLE; DRUG CLEARANCE; DRUG HALF LIFE; FEMALE; HUMAN; MALE; PRIORITY JOURNAL;

EID: 0030049679     PISSN: 00316970     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF00203785     Document Type: Article

References (18)

1. Vallee BL, Falchuk KH (1993) The biochemical basis of zinc physiology. Physiol Rev 73: 79-118
2. Vallee BL, Wacker WEC, Bartholomay AF, Hoch FL (1957) Zinc metabolism in hepatic dysfunction. II. Correlation of metabolic patterns with biochemical findings. N Engl J Med 257: 1055-1065
3. Valberg LS, Flanagan PR, Ghent CN, Chamberlain MJ (1985) Zinc absorption and leukocyte zinc in alcoholic and nonalcoholic cirrhosis. Dig Dis Sci 30: 329-333
4. McClain CJ, Van Thiel DH, Parker S, Badzin LK, Gilbert H (1979) Alterations in zinc, vitamin A, and retinol-binding protein in chronic alcoholics: a possible mechanism for night blindness and hypogonadism. Alcohol Clin Exp Res 3: 135-141
5. Kiilerich S. Dietrichson O, Loud FB, Naestoft J, Christoffersen P, Juhl E, Kjems G, Christiansen C (1980) Zinc depletion in alcoholic liver diseases. Scand J Gastroenterol 15: 363-367
6. Hartoma TR, Sotaniemi EA, Pelkonen O, Ahlqvist J (1977) Serum zinc and serum copper and indices of drug metabolism in alcoholics. Eur J Clin Pharmacol 12: 147-151
7. Golden MHN (1989) The diagnosis of zinc deficiency. In: Mills CF (ed) Zinc in Human biology. Springer, Berlin, pp 323-333
8. Sonne J, Døssing M, Loft S, Andreasen PB (1985) Antipyrine clearance in pneumonia. Clin Pharmacol Ther 37: 701-704
9. Andreasen PB, Vesell ES (1974) Comparison of plasma levels of antipyrine, tolbutamide, and warfarin after oral and intravenous administration. Clin Pharmacol Ther 16: 1059-1065
10. Døssing M, Poulsen HE, Andreasen PB, Tygstrup N (1982) A simple method for determination of antipyrine clearance. Clin Pharmacol Ther 32: 392-396
11. McClain CJ, Antonow DR, Cohen DA, Shedlofsky SI (1986) Zinc metabolism in alcoholic liver disease. Alcohol Clin Exp Res 10: 582-589
12. Barry M, Keeling PWN, Feely J (1990) Tissue zinc status and drug elimination in patients with chronic liver disease. Clin Sci 78: 547-549
13. Poulsen HE, Loft S (1988) Antipyrine as a model drug to study hepatic drug-metabolizing capacity. J Hepatol 6: 374-382
14. Andreasen PB, Ranek L, Statland BE, Tygstrup N (1974) Clearance of antipyrine-dependence of quantitative liver function. Eur J Clin Invest 4: 129-134
15. King JC (1990) Assessment of zinc status. J Nutr 120 [Suppl] 11: 1474-1479
16. Gibson RS (1990) Assessment of trace-element status. In: Principles of nutritional Assessment. Oxford University Press, New York, pp 511-575
17. Barry MG, Macmathuna P, Younger K, Keeling PW, Feely J (1991) Effect of zinc supplementation on oxidative drug metabolism in patients with hepatic cirrhosis. Br J Clin Pharmacol 31: 488-491
18. Weismann K, Christensen E, Dreyer V (1979) Zinc supplementation in alcoholic cirrhosis. A double-blind clinical trial. Acta Med Scand 205: 361-366