Host genotype controls the ability of the ISGF3 complex to activate transcription of IFN-lnducible genes

Journal of Cellular Biochemistry

Volumn 60, Issue 1, 1996, Pages 83-94

  Gariglio, Marisa ^a   Foresta, Paola ^a   Ying, Guo Cuang ^a   Gaboli, Mirella ^a   Lembo, David ^a   Landoffo, Santo ^a,b  

^a UNIVERSITY OF TURIN   (Italy)

^b Istituto di Microbiologia   (Italy)

Author keywords

Host genotype; IFNs; ISGF3 complex

Indexed keywords

FELIS CATUS; ANIMALIA;

INTERFERON;

ANIMAL CELL; ARTICLE; CELL STRAIN 3T3; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE EXPRESSION REGULATION; GENE INDUCTION; GENOTYPE; INTERFERON PRODUCTION; INTRACELLULAR TRANSPORT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN PROCESSING; PROTEIN TRANSPORT; REPORTER GENE; TRANSCRIPTION INITIATION;

3T3 CELLS; ANIMALS; BASE SEQUENCE; CHLORAMPHENICOL O-ACETYLTRANSFERASE; DNA-BINDING PROTEINS; FEMALE; GENES, REPORTER; GENOTYPE; INTERFERON-ALPHA; INTERFERON-STIMULATED GENE FACTOR 3; INTERFERON-STIMULATED GENE FACTOR 3, GAMMA SUBUNIT; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; OLIGONUCLEOTIDE PROBES; PROMOTER REGIONS (GENETICS); RNA, MESSENGER; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSFECTION;

EID: 0030049423     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/(sici)1097-4644(19960101)60:1<83::aid-jcb11>3.0.co;2-l     Document Type: Article

References (44)

1. Boshart M, Klüppel M, Schmidt A, Schütz G, Luckow B (1992): Reporter constructs with low background activity utilizing the cat gene. Gene 110:129-130.
2. Briggs JA, Burrus GR, Stickney BD, Briggs RC (1992): Cloning and expression of the human myeloid cell nuclear differentiation antigen: Regulation by Interferon α. J Cell Biochem 49:82-92.
3. Briggs RC, Briggs JA, Ozer J, Sealy L, Dworkin LL, Kingsmore SF, Seldin MF, Kaur GP, Athwal RS, Dessypris EN (1994): The human myeloid cell nuclear differentiation antigen gene is one of at least two related interferoninducible genes located on chromosome 1q that are expressed specifically in hematopoietic cells. Blood 83:2153-2162.
4. Burrus GR, Briggs JA, Briggs RC (1992): Characterization of the human myeloid cell nuclear differentiation antigen: Relationship to interferon-inducible proteins. J Cell Biochem 48:190-202.
5. Choubey D, Lengyel P (1992): Interferon action: Nucleolar and nucleoplasmic localization of the interferon-inducible 72-kD protein that is encoded by the Ifi 204 gene from the gene 200 cluster. J Cell Biol 116:1333-1341.
6. Choubey D, Lengyel P (1993): Interferon action: Cytoplasmic and nuclear localization of the interferon-inducible 52-kD protein that is encoded by the Ifi 202 gene from the gene 200 cluster. J IFN Res 13:43-52.
7. Choubey D, Snoddy J, Chaturvedi V, Toniato E, Opdenakker G, Thakur A, Samanta H, Engel DA, Lengyel P (1989): Interferons as gene activators. Indications for repeated gene duplication during the evolution of a cluster of interferon-activable genes on murine chromosome 1. J Biol Chem 264:17182-17189.
8. Darnell JE Jr, Kerr EM, Stark GR (1994): Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 264:1415-1421.
9. De Mayer E, De Mayer-Guignard J (1988): "Interferons and Other Regulatory Cytokines." New York: John Wiley & Sons, Inc.
10. Dignam JD, Lebovitz RM, Roeder RG (1983): Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res 11:1475-1489.
11. Fu X-Y, Schindler C, Improta T, Aebersold R, Darnell JE, Jr (1992): The proteins of ISGF-3, the interferon α-induced transcriptional activator, define a gene family involved in signal transduction. Proc Natl Acad Sci USA 89:7840-7843.
12. Gariglio M, Panico S, Cavallo G, Choubey D, Lengyel P, Landolfo S (1992): Impaired transcription of the poly rI:rC- and interferon-activatable 202 gene in mice and cell lines from the C57BL/6 strain. Virology 187:115-123.
13. Gariglio M, Gaboli M, Mana C, Ying G-G, Gribaudo G, Cavallo R, Landollo S (1994): Characterization of nuclear factors involved in 202 gene induction by interferon-α in murine leukemia cells. Eur J Biochem 221:731-739.
14. German CM, Moffat LF, Howard BH (1982): Recombinant genomes which express cloramphenicol acetyltransferase in mammalian cells. Mol Cell Biol 2:1044-1051.
15. Gribaudo G, Toniato E, Engel DA, Lengyel P (1987): Interferons as gene activators. Characteristics of an interferon-activatable enhancer. J Biol Chem 262:11878-11883.
16. Hubseher U (1987): Double replica southwestern. Nucleic Acids Res 15:5486.
17. Ihle JN, Witthuhn BA, Quelle FW, Yamamoto K, Thierfelder WE, Kreider B, Silvennoinen O (1994): Signaling by the cytokine receptor superfamily: JAKs and STATs. TIBS 19:222-227.
18. Improta T, Schindler C, Horvath CM, Kerr IM, Stark GR, Darnell JE Jr (1994): Transcription factor ISGF-3 formation requires phosphorylated Stat91 protein, but Stat113 protein is phosphorylated independently of Stat91 protein. Proc Natl Acad Sci USA 91:4776-4780.
19. Ito N, Gribaudo G, Toniato E, Thakur A, Yagi Y, Barbosa J, Kamarck M, Ruddle FH, Lengyel P (1989): Interferons as gene activators: Identification of an interferon responsive "GA box" in a murine gene. In Sporn M, et al. (eds): "UCLA Symposium on Growth Inhibitory and Cytotoxic Polypeptides." New York: Alan R. Liss, pp 169-178.
20. John J, McKendry R, Pellegrini S, Flavell D, Kerr IM, Stark GR (1991): Isolation and characterization of a new mutant human cell line unresponsive to alpha and beta interferons. Mol Cell Biol 11:4189-4195.
21. Kerr IM, Stark GR (1991): The control of interferon-inducible gene expression. FEBS Lett 285:194-198.
22. Kessler DS, Veals SA, Fu X-Y, Levy DE (1990): IFN-alpha regulates nuclear translocation and DNA-binding affinity of ISGF3, a multimeric transcriptional activator. Genes Dev 4:1753-1765.
23. Levy DE, Kessler DS, Pine R, Darnell JE, Jr (1989): Cytoplasmic activation of ISGF3, the positive regulator of interferon-α-stimulated transcription, reconstituted in vitro. Genes Dev 3:1362-1371
24. Loh JE, Schindler C, Ziemiecki A, Harpur AG, Wilks AF, Flavell RA (1994): Mutant cell lines unresponsive to alpha/beta and gamma interferon are defective in tyrosine phosphorylation of ISGF-3α components. Mol Cell Biol 14:2170-2179.
25. MacDonald RJ, Swift GH, PrzybylaAE, Chirgwin JM (1987): Isolation of RNA using guanidinium salts. In Berger SL, Kimmel AR (eds): "Methods in Enzymology." San Diego: Academic Press, pp 219-227.
26. Müller M, Laxton C, Briscoe J, Schindler C, Improta T, Darnell JE Jr, Stark GR, Kerr IM (1993): Complementation of a mutant cell line: Central role of the 91 kDa polypeptide of ISGF3 in the interferon-α and -γ signal transduction pathways. Embo J 12:4221-4228.
27. Noteborn M, Arnheiter H, Richter-Mann L, Browing H, Weissmann C (1987): Transport of the murine Mx protein into the nucleus is dependent on a basic carboxy-terminal sequence. J IFN Res 7:657-669.
28. Opdenakker G, Snoddy J, Choubey D, Toniato E, Pravtcheva DD, Seldin MF, Ruddle FH, Lengyel P (1989): Interferons as gene activators: A cluster of six interferon-activatable genes is linked to the erythroid α-spectrin locus on murine chromosome 1. Virology 171:568-578.
29. Pine R, Decker T, Kessler DS, Levy DE, Darnell JE Jr (1990): Purification and cloning of interferon-stimulated-gene factor 2 (ISGF-2): ISGF2 (IRF-1) can bind to the promoters of both beta interferon- and interferon-stimulated genes but is not a primary transcriptional activator of either. Mol Cell Biol 10:2448-2457.
30. Revel M, Chebath J (1986): Interferon-activated genes. Trends Biochem Sci 11:66-70.
31. Samanta H, Engel DA, Chao HM, Thakur A, Garcia-Blanco MA, Lengyel P (1986): Interferons as gene activators. Cloning of the 5′ terminus and the control segment of an interferon activated gene. J Biol Chem 261:11849-11858.
32. Sambrook J, Fritsch EF, Maniatis T (1989): "Molecular Cloning: A Laboratory Manual." Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press.
33. Schindler C, Fu X-Y, Improta T, Aebersold R, Darnell JE Jr (1992a): Proteins of transcription factor ISGF-3: One gene encodes the 91 and 84-kDa ISGF3-3 proteins that are activated by interferon-α. Proc Natl Acad Sci USA 89:7836-7839.
34. Schindler C, Shuai K, Prezioso VR, Darnell JE Jr (1992b): Interferon-dependent tyrosine phosphorylation of a latent cytoplasmic transcription factor. Science 257:809-813.
35. Shuai K, Ziemiecki A, Wilks AF, Harpur AG, Sadowski HB, Gilman MZ, Darnell JE (1993): Polypeptide signalling to the nucleus through tyrosine phosphorylation of Jak and Stat proteins. Nature 366:580-583.
36. Tannenbaum CS, Major J, Ohmori Y, Hamilton TA (1993): A lipopolysaccharide-mducible macrophage gene (D3) is a new member of an interferon-inducible gene cluster and is selectively expressed in mononuclear phagocytes. J Leukoc Biol 53:563-568.
37. Trapani JA, Browne KA, Dawson MJ, Ramsay RG, Eddy RL, Shows TB, White PC, Dupont B (1992): A novel gene constitutively expressed in human lymphoid cells is inducible with interferon-γ in myeloid cells. Immunogen 36:369-376.
38. Veals SA, Schindler C, Leonard D, Fu X-Y, Aebersold R, Darnell JE Jr, Levy DE (1992): Subunit of an alpha-interferon-responsive transcription factor is related to Interferon regulatory factor and Myb families of DNA-binding proteins. Mol Cell Biol 12:3315-3324.
39. Velazquez LM, Fellous M, Stark GR, Pellegrini S (1992): A protein tyrosine kinase in the Interferon α/β signaling pathway. Cell 70:313-322.
40. Watling D, Guschin D, Muller M, Silvennoinen O, Witthuhn BA, Quelle FW, Rogers NC, Schindler C, Stark GR, Ihle JN, Kerr IM (1993): Complementation by the protein tyrosine kinase JAK2 of a mutant cell line defective in the interferon-γ signal transduction pathway. Nature 366:168-170.
41. Wigler M, Pellicer A, Silverstein S, Axel R, Urlaub G, Chasin L (1979): DNA-mediated transfer of the adenine phosphoribosyltransferase locus in mammalian cells. Proc Natl Acad Sci USA 76:1373-1376.
42. Zhong Z, Wen Z, Darnell JE, Jr (1994a): Stat3: A STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6. Science 264:95-98.
43. Zhong Z, Wen Z, Darnell JE, Jr (1994b): Stat3 and Stat4: Members of the family of signal transducers and activators of transcription. Proc Natl Acad Sci USA 91:4806-4810.
44. Ziemiecki A, Harpur AG, Wilks AF (1994): JAK protein tyrosine kinases: Their role in cytokine signalling. Trends Cell Biol 4:207-212.