메뉴 건너뛰기




Volumn 66, Issue 3, 1996, Pages 1125-1130

Effects of methylprednisolone on extracellular lactic acidosis and amino acids after severe compression injury of rat spinal cord

Author keywords

Amino acids; Arginine; Glutamate; Lactate; Methylprednisolone; Microdialysis; Rat; Spinal cord; Trauma

Indexed keywords

4 AMINOBUTYRIC ACID; ALANINE; AMINO ACID; ARGININE; ASPARTIC ACID; FREE RADICAL; GLUTAMINE; GLYCINE; HISTIDINE; LACTIC ACID; METHYLPREDNISOLONE; TAURINE; THREONINE; TYROSINE;

EID: 0030049084     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1996.66031125.x     Document Type: Article
Times cited : (31)

References (35)
  • 1
    • 0019962854 scopus 로고
    • Microvascular perfusion and metabolism in injured spinal cord after methylprednisolone treatment
    • Anderson D. K., Means E. D., Waters T. R., and Green E. S. (1982) Microvascular perfusion and metabolism in injured spinal cord after methylprednisolone treatment. J. Neurosurg. 56, 106-113.
    • (1982) J. Neurosurg. , vol.56 , pp. 106-113
    • Anderson, D.K.1    Means, E.D.2    Waters, T.R.3    Green, E.S.4
  • 2
    • 0022224135 scopus 로고
    • Lipid hydrolysis and peroxidation in injured spinal cord: Partial protection with methylprednisolone or vitamin E and selenium
    • Anderson D. K., Saunders R. D., Demediuk P., Dugan L. L., Braughler J. M., Hall E. D., Means E. D., and Horrocks L. A. (1985) Lipid hydrolysis and peroxidation in injured spinal cord: partial protection with methylprednisolone or vitamin E and selenium. CNS Trauma 2, 257-267.
    • (1985) CNS Trauma , vol.2 , pp. 257-267
    • Anderson, D.K.1    Saunders, R.D.2    Demediuk, P.3    Dugan, L.L.4    Braughler, J.M.5    Hall, E.D.6    Means, E.D.7    Horrocks, L.A.8
  • 4
    • 0020612791 scopus 로고
    • Lactate and pyruvate metabolism in injured cat spinal cord before and after a single large intra-venous dose of methylprednisolone
    • Braughler J. M. and Hall E. D. (1983) Lactate and pyruvate metabolism in injured cat spinal cord before and after a single large intra-venous dose of methylprednisolone. J. Neurosurg. 59, 256-261.
    • (1983) J. Neurosurg. , vol.59 , pp. 256-261
    • Braughler, J.M.1    Hall, E.D.2
  • 5
    • 0342492672 scopus 로고
    • Role of nitric oxide in focal cerebral ischemia
    • Krieglstein J. and Schwenk H. O., eds, Wissenschaftliche Verlagsgesellbchaft mbH, Stuttgart
    • Buisson A., Margaill I., Allix M., Callebert J., Plotkine M., and Boulu R. G. (1992) Role of nitric oxide in focal cerebral ischemia, in Pharmacology of Cerebral Ischemia (Krieglstein J. and Schwenk H. O., eds), pp. 417-426. Wissenschaftliche Verlagsgesellbchaft mbH, Stuttgart.
    • (1992) Pharmacology of Cerebral Ischemia , pp. 417-426
    • Buisson, A.1    Margaill, I.2    Allix, M.3    Callebert, J.4    Plotkine, M.5    Boulu, R.G.6
  • 6
    • 0020464082 scopus 로고
    • Further studies on free-radical pathology in the major central nervous system disorders: Effect of very high doses of methylprednisolone on the functional outcome, morphology, and chemistry of experimental spinal cord impact injury
    • Demopoulos H. B., Flamm E. S , Seligman M L., Pietronigro D. D., Tomasula J., and DeCrescito V. (1982) Further studies on free-radical pathology in the major central nervous system disorders: effect of very high doses of methylprednisolone on the functional outcome, morphology, and chemistry of experimental spinal cord impact injury. Can. J. Physiol. Pharmacol. 60, 1415-1424.
    • (1982) Can. J. Physiol. Pharmacol. , vol.60 , pp. 1415-1424
    • Demopoulos, H.B.1    Flamm, E.S.2    Seligman, M.L.3    Pietronigro, D.D.4    Tomasula, J.5    DeCrescito, V.6
  • 7
    • 0026485095 scopus 로고
    • Exudation of fibronectin and albumin after spinal cord injury in rats
    • Farooque M., Zhang Y., Holtz A., and Olsson Y. (1992) Exudation of fibronectin and albumin after spinal cord injury in rats. Acta Neuropathol. (Berl.) 84, 613-620.
    • (1992) Acta Neuropathol. (Berl.) , vol.84 , pp. 613-620
    • Farooque, M.1    Zhang, Y.2    Holtz, A.3    Olsson, Y.4
  • 8
    • 0028326586 scopus 로고
    • Effect of the 21-aminosteroid U74006F and methylprednisolone on motor function recovery and oedema after spinal cord compression in rats
    • Farooque M., Olsson Y , and Holtz A. (1994) Effect of the 21-aminosteroid U74006F and methylprednisolone on motor function recovery and oedema after spinal cord compression in rats. Acta Neurol Scand. 89, 36-41.
    • (1994) Acta Neurol Scand. , vol.89 , pp. 36-41
    • Farooque, M.1    Olsson, Y.2    Holtz, A.3
  • 9
    • 0028899853 scopus 로고
    • Astrocytic reaction after graded spinal cord compression in rats. Immunohistochemical studies on glial fibrillary acidic protein and vimentin
    • Farooque M., Badonic T., Olsson Y., and Holtz A. (1995) Astrocytic reaction after graded spinal cord compression in rats. Immunohistochemical studies on glial fibrillary acidic protein and vimentin. J. Neurotrauma 12, 41-51.
    • (1995) J. Neurotrauma , vol.12 , pp. 41-51
    • Farooque, M.1    Badonic, T.2    Olsson, Y.3    Holtz, A.4
  • 10
    • 0022469346 scopus 로고
    • Iron promoters of the Fenton reaction and lipid peroxidation can be released from haemoglobin by peroxides
    • Gutteridge J. M. (1986) Iron promoters of the Fenton reaction and lipid peroxidation can be released from haemoglobin by peroxides. FEBS Lett. 201, 291-295.
    • (1986) FEBS Lett. , vol.201 , pp. 291-295
    • Gutteridge, J.M.1
  • 11
    • 0020048289 scopus 로고
    • +)-ATPase activity Dose-response analysis during first hour after contusion injury in the cat
    • +)-ATPase activity Dose-response analysis during first hour after contusion injury in the cat. J. Neurosurg. 57, 247-253.
    • (1982) J. Neurosurg. , vol.57 , pp. 247-253
    • Hall, E.D.1    Braughler, J.M.2
  • 12
    • 0020404988 scopus 로고
    • Glucocorticoid mechanisms in acute spinal cord injury. A review and therapeutic rationale
    • Hall E. D. and Braughler J. M. (1982b) Glucocorticoid mechanisms in acute spinal cord injury. A review and therapeutic rationale. Surg. Neurol. 18, 320-327.
    • (1982) Surg. Neurol. , vol.18 , pp. 320-327
    • Hall, E.D.1    Braughler, J.M.2
  • 14
    • 0021267414 scopus 로고
    • Effects of a single large dose of methyl prednisolone sodium succinate on experimental posttraumatic spinal cord ischemia. Dose-response and time-action analysis
    • Hall E., Wolf D., and Braughler J. (1984) Effects of a single large dose of methyl prednisolone sodium succinate on experimental posttraumatic spinal cord ischemia. Dose-response and time-action analysis. J. Neurosurg. 61, 124-130.
    • (1984) J. Neurosurg. , vol.61 , pp. 124-130
    • Hall, E.1    Wolf, D.2    Braughler, J.3
  • 15
    • 0024443556 scopus 로고
    • Simultaneous determination of lactate, pyruvate, and ascorbate in microdialysis samples from rat brain, blood, fat, and muscle using high-performance liquid chromatography
    • Hallstrom A., Carlsson A., Hillered L., and Ungerstedt U. (1989) Simultaneous determination of lactate, pyruvate, and ascorbate in microdialysis samples from rat brain, blood, fat, and muscle using high-performance liquid chromatography. J. Pharmacol. Methods 22, 113-124.
    • (1989) J. Pharmacol. Methods , vol.22 , pp. 113-124
    • Hallstrom, A.1    Carlsson, A.2    Hillered, L.3    Ungerstedt, U.4
  • 16
    • 0024556759 scopus 로고
    • 14C-iodoantipyrine autoradiography during and after graded spinal cord compression in rats
    • 14C-iodoantipyrine autoradiography during and after graded spinal cord compression in rats. Surg. Neurol. 31, 350-360
    • (1989) Surg. Neurol. , vol.31 , pp. 350-360
    • Holtz, A.1    Nyström, B.2    Gerdin, B.3
  • 17
    • 0025032726 scopus 로고
    • Effect of methylprednisolone on motor function and spinal cord blood flow after spinal cord compression in rats
    • Holtz A., Nyström B., and Gerdin B. (1990) Effect of methylprednisolone on motor function and spinal cord blood flow after spinal cord compression in rats. Acta Neurol. Scand. 82, 68-73.
    • (1990) Acta Neurol. Scand. , vol.82 , pp. 68-73
    • Holtz, A.1    Nyström, B.2    Gerdin, B.3
  • 18
    • 0022494104 scopus 로고
    • Morphometric assessment of drug effects in experimental spinal cord injury
    • Iizuka H., Iwasaki Y., Yamamoto T., and Kadoya S. (1986) Morphometric assessment of drug effects in experimental spinal cord injury. J. Neurosurg, 65, 92-98.
    • (1986) J. Neurosurg , vol.65 , pp. 92-98
    • Iizuka, H.1    Iwasaki, Y.2    Yamamoto, T.3    Kadoya, S.4
  • 19
    • 24444436724 scopus 로고
    • High performance liquid chromatographic determination of subpicomole amounts of amino acids by precolumn fluorescence derivatization with ophthaldialdehyde
    • Lindroth P. and Mopper K. (1979) High performance liquid chromatographic determination of subpicomole amounts of amino acids by precolumn fluorescence derivatization with ophthaldialdehyde. Anal. Chem. 51, 1667-1674.
    • (1979) Anal. Chem. , vol.51 , pp. 1667-1674
    • Lindroth, P.1    Mopper, K.2
  • 20
    • 0028762647 scopus 로고
    • Excitatory amino acids as a final common pathway for neurologic disorders
    • Lipton S. A. and Rosenberg P. A. (1994) Excitatory amino acids as a final common pathway for neurologic disorders. N. Engl. J. Med. 330, 613-622.
    • (1994) N. Engl. J. Med. , vol.330 , pp. 613-622
    • Lipton, S.A.1    Rosenberg, P.A.2
  • 21
    • 0027285503 scopus 로고
    • Methylprednisolone reduces excitatory amino acid release following experimental spinal cord injury
    • Liu D. and McAdoo D. J. (1993) Methylprednisolone reduces excitatory amino acid release following experimental spinal cord injury. Brain Res. 609, 293-297.
    • (1993) Brain Res. , vol.609 , pp. 293-297
    • Liu, D.1    McAdoo, D.J.2
  • 23
    • 0025182940 scopus 로고
    • Changes in cortical extracellular levels of energy-related metabolites and amino acids following concussive brain injury in rats
    • Nilsson P., Hillered L., Ponten U., and Ungerstedt U. (1990) Changes in cortical extracellular levels of energy-related metabolites and amino acids following concussive brain injury in rats J. Cereb. Blood Flow Metab. 10, 631-637.
    • (1990) J. Cereb. Blood Flow Metab. , vol.10 , pp. 631-637
    • Nilsson, P.1    Hillered, L.2    Ponten, U.3    Ungerstedt, U.4
  • 24
    • 0024210464 scopus 로고
    • Methodological analysis of an experimental spinal cord compression model in the rat
    • Nyström B., Berglund J. E., and Bergquist E. (1988) Methodological analysis of an experimental spinal cord compression model in the rat. Acta Neurol. Scand. 78, 460-466.
    • (1988) Acta Neurol. Scand. , vol.78 , pp. 460-466
    • Nyström, B.1    Berglund, J.E.2    Bergquist, E.3
  • 25
    • 0025162091 scopus 로고
    • Alteration in extracellular amino acids after traumatic spinal cord injury
    • Panter S. S., Yum S. W., and Faden A. I. (1990) Alteration in extracellular amino acids after traumatic spinal cord injury. Ann Neurol. 27, 96-99.
    • (1990) Ann Neurol. , vol.27 , pp. 96-99
    • Panter, S.S.1    Yum, S.W.2    Faden, A.I.3
  • 26
    • 0344314014 scopus 로고
    • Traumatic brain injury. The pathobiology of injury and repair
    • Gorio A., ed, Raven Press, New York
    • Povlishock J. T. (1993) Traumatic brain injury. The pathobiology of injury and repair, in Neuroregeneration (Gorio A., ed), pp. 185-216. Raven Press, New York.
    • (1993) Neuroregeneration , pp. 185-216
    • Povlishock, J.T.1
  • 27
    • 0025874048 scopus 로고
    • Peroxynitrite-induced membrane lipid peroxidation: The cytotoxic potential of superoxide and nitric oxide
    • Radi R., Beckman J. S., Bush K. M., and Freeman B. A. (1991) Peroxynitrite-induced membrane lipid peroxidation: the cytotoxic potential of superoxide and nitric oxide. Arch. Biochem. Biophys. 288, 481-487.
    • (1991) Arch. Biochem. Biophys. , vol.288 , pp. 481-487
    • Radi, R.1    Beckman, J.S.2    Bush, K.M.3    Freeman, B.A.4
  • 29
    • 0027198869 scopus 로고
    • Basic mechanisms of traumatic brain damage
    • Siesjö B. K. (1993) Basic mechanisms of traumatic brain damage. Ann. Emerg. Med. 22, 959-969.
    • (1993) Ann. Emerg. Med. , vol.22 , pp. 959-969
    • Siesjö, B.K.1
  • 31
    • 0021993608 scopus 로고
    • Ferritin and superoxide-depcndent lipid peroxidation
    • Thomas C. E., Morehouse L. A., and Aust S. D. (1985) Ferritin and superoxide-depcndent lipid peroxidation. J. Biol. Chem. 260, 3275-3280.
    • (1985) J. Biol. Chem. , vol.260 , pp. 3275-3280
    • Thomas, C.E.1    Morehouse, L.A.2    Aust, S.D.3
  • 32
    • 0022471749 scopus 로고
    • Regional distribution and extracellular levels of amino acids in rat central nervous system
    • Tossman U., Jonsson G., and Ungerstedt U. (1986) Regional distribution and extracellular levels of amino acids in rat central nervous system. Acta Physiol. Scand. 127, 533-545.
    • (1986) Acta Physiol. Scand. , vol.127 , pp. 533-545
    • Tossman, U.1    Jonsson, G.2    Ungerstedt, U.3
  • 33
    • 0023217185 scopus 로고
    • In vivo microdialysis - A new approach to the analysis of neurotransmitter in the brain
    • Ungerstedt U. and Hallström Å. (1987) In vivo microdialysis - a new approach to the analysis of neurotransmitter in the brain. Life Sci. 41, 861-864.
    • (1987) Life Sci. , vol.41 , pp. 861-864
    • Ungerstedt, U.1    Hallström, Å.2
  • 34
    • 0019960776 scopus 로고
    • Effect of high dose corticosteroid therapy on blood flow, evoked potentials, and extracellular calcium in experimental spinal cord injury
    • Young W. and Flamm R. S. (1982) Effect of high dose corticosteroid therapy on blood flow, evoked potentials, and extracellular calcium in experimental spinal cord injury. J. Neurosurg. 57, 667-673.
    • (1982) J. Neurosurg. , vol.57 , pp. 667-673
    • Young, W.1    Flamm, R.S.2
  • 35
    • 0027287740 scopus 로고
    • Time course of energy perturbation after compression trauma to the spinal cord
    • Zhang Y., Hillered L., Olsson Y., and Holtz A. (1993) Time course of energy perturbation after compression trauma to the spinal cord. Surg. Neurol. 297, 297-304.
    • (1993) Surg. Neurol. , vol.297 , pp. 297-304
    • Zhang, Y.1    Hillered, L.2    Olsson, Y.3    Holtz, A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.