Hypothalamic-pituitary-adrenal axis in corticosteroid-resistant bronchial asthma

American Journal of Respiratory and Critical Care Medicine

Volumn 153, Issue 2, 1996, Pages 557-560

  Lane, Stephen J ^a   Atkinson, Beryl A ^a   Swaminathan, Ramasamyiyer ^a   Lee, Tak H ^a  

^a GUY S HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOTROPIN; DEXAMETHASONE; HYDROCORTISONE; SALBUTAMOL;

ARTICLE; ASTHMA; CLINICAL ARTICLE; CORTICOTROPIN BLOOD LEVEL; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLUOROMETRY; HUMAN; HUMAN CELL; HUMAN TISSUE; HYDROCORTISONE RELEASE; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; IMMUNORADIOMETRIC ASSAY; IMMUNOSUPPRESSIVE TREATMENT; MALE; ORAL DRUG ADMINISTRATION; PATHOPHYSIOLOGY; PRIORITY JOURNAL; STEROID THERAPY;

EID: 0030048947     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.153.2.8564097     Document Type: Article

References (24)

1. Carmichael, J., I. C. Paterson, P. Diaz, G. K. Crompton, A. B. Kay, and I. W. B. Grant. 1981. Corticosteroid resistance in chronic asthma. B.M.J. 282:1419-1422.
2. Wilkinson, J. R. W., A. E. G. Crea, T. J. H. Clark, and T. H. Lee. 1989. Identification and characterisation of a monocyte-derived neutrophil-activating factor in corticosteroid-resistant bronchial asthma. J. Clin. Invest. 84:1930-1941.
3. Lee, T. H., and S. J. Lane. 1992. The role of macrophages in the mechanisms of airway inflammation in asthma. Am. Rev. Respir. Dis. 145:S27-S30.
4. Lane, S. J., J. R. W. Wilkinson, G. M. Cochrane, T. H. Lee, and J. P. Arm. 1993. Differential in vitro regulation by glucocorticoids of monocyte-derived cytokine generation in glucocorticoid resistant bronchial athma. Am. Rev. Respir. Dis. 147:690-696.
5. Wilkinson, J. R. W., S. J. Lane, and T. H. Lee. 1991. The effects of corticosteroids on cytokine generation and expression of activation antigens by monocytes in bronchial asthma. Int. Arch. Allergy Clin. Immunol. 94:220-221.
6. Kay, A. B., P. Diaz, J. Carmichael, and I. W. B. Grant. 1981. Corticosteroid-resistant chronic asthma and monocyte complement receptors. Clin. Exp. Immunol. 44:576-580.
7. Poznansky, M. C., A. C. H. Gordon, J. G. Dolas, A. S. Krajewski, A. H. Wyllie, and I. W. B. Grant. 1984. Resistance to methylprednisolone in cultures of blood mononuclear cells from glucocorticoidresistant asthmatic patients. Clin. Sci. 67:639-645.
8. Wyllie, A. H., M. C. Poznansky, and A. C. H. Gordon. 1986. Glucocorticoid resistant asthma: evidence for a defect in mononuclear cells. In A. B. Kay, editor. Asthma: Clinical Pharmacology and Therapeutic Progress. Blackwell Scientific, Oxford. 306-304.
9. Corrigan, C. J., P. H. Brown, N. C. Barnes, J.-J. Tsai, A. J. Frew, and A. B. Kay. 1991. Peripheral blood T lymphocyte activation and comparison of the T lymphocyte inhibitory effects of glucocorticoids and cyclosporin A. Am. Rev. Respir. Dis. 144:1026-1032.
10. Lane, S. J., A. R. Sousa, R. N. Poston, and T. H. Lee. 1993. In vivo cutaneous tuberculin response to prednisolone in corticosteroid resistant bronchial asthma. J. Allergy Clin. Immunol. 1991:A221.
11. Sher, E. R., D. Y. M. Leung, W. Surs, J. C. Kam, G. Zeig, A. K. Kamada, and S. J. Szefler. 1994. Steroid resistant asthma: cellular mechanisms contributing to inadequate response to therapy. J. Clin. Invest. 93:133-139.
12. Lane, S. J., J. B. D. Palmer, I. F. Skidmore, and T. H. Lee. 1990. Corticosteroid pharmacokinetics in asthma. Lancet 336:1265.
13. Lane, S. J., and T. H. Lee. 1991. Glucocorticoid receptor characteristics in monocytes of patients with corticosteroid-resistant bronchial asthma. Am. Rev. Respir. Dis. 143:1020-1024.
14. Corrigan, C. J., P. H. Brown, N. C. Barnes, S. J. Szefler, J.-J. Tsai, A. J. Frew, and A. B. Kay. 1991. Glucocorticoid pharmacokinetics, glucocorticoid receptor characteristics, and inhibition of peripheral blood T cell proliferation by glucocorticoids in vitro. Am. Rev. Respir. Dis. 144:1016-1025.
15. Lane, S. J., J. P. Arm, D. Z. Staynov, and T. H. Lee. 1994. Chemical mutational analysis of the human glucocorticoid receptor cDNA in glucocorticoid-resistant bronchial asthma. Am. J. Respir. Mol. Cell Biol. 11:42-48.
16. Adcock, I. M., S. J. Lane, C. R. Brown, T. H. Lee, and P. J. Barnes. 1995. Differences in binding of glucocorticoid receptor to DNA in steroid-resistant. J. Immunol. 154:3500-3505.
17. Smith, E. K., and C. A. Muchlbaecher. 1969. A fluorimetric method for plasma cortisol and transcortin. Clin. Chem. 15:961-968.
18. Tsigos, C., and G. P. Chrousos. 1994. Physiology of the hypothalamic-pituitary-adrenal axis in health and dysregulation in psychiatric and autoimmune disorders. Endocrinol. Metab. Clin. North Am. 23: 451-466.
19. Waltman, C., M. R. Blackman, G. P. Chrousos, C. Reimann, and C. Harman. 1991. Spontaneous and glucocorticoid inhibited adrenocorticotrophic hormone and cortisol secretion are similar in healthy young and old men. J. Clin. Endocrinol. Metab. 73:495-502.
20. Hohnloser, J., K. Von Werder, and O. Muller. 1989. Acute dexamethasone suppression of ACTH secretion stimulated by human corticotrophin releasing hormone: AVP and hyperglycaemia. Clin. Endocrinol. 31:175-184.
21. Petrides, J. S., G. P. Myeller, K. T. Kalogeras, G. P. Chrousos, P. W. Gold, and P. A. Deuster. 1994. Exercise-induced activation of the hypothalamic-pituitary-adrenal axis: marked differences in the sensitivity to glucocorticoid suppression. J. Clin. Endocrinol. Metab. 79:377-383.
22. Keitner, G. I., C. E. Ryan, R. Kohn, T. W. Miller, W. H. Norman, and W. A. Brown. 1992. Age and the dexamethasone suppression tests: results from a broad unselected patient population source. Psychiatry Res. 44:9-20.
23. Gispes-de Wied, C. C., H. D'Harman, W. M. Verhoeven, et al. 1993. Inhibition of the pituitary adrenal axis with dexamethasone and cortisol in depressed patients and healthy subjects: a dose-response study. Psychoneuroendocrinology 18:191-204.
24. Haut, G. E., B. T. O'Sullivan, G. F. Johnson, and I. D. Caterson. 1991. Effect of high plasma dexamethasone boost on DS7-sensitivity: a dose-response study in depressed patients and controls. Psychiatry Res. 36:209-222.