Synthetic studies of 8-carbomoylimidazo-[5,1-D]-1,2,3,5-tetrazin-4(3H)-one: A key derivative of antitumour drug temozolomide

Bioorganic and Medicinal Chemistry Letters

Volumn 6, Issue 2, 1996, Pages 185-188

  Wang, Yongfeng ^a,b   Stevens, Malcolm F G ^b  

^a ASTON UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; IMIDAZO[5,1 D][1,2,3,5]TETRAZINE DERIVATIVE; TEMOZOLOMIDE; TETRAZINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DRUG SYNTHESIS; REACTION ANALYSIS;

EID: 0030048592     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0960-894X(95)00586-I     Document Type: Article

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9. 2SO] 162.37, 140.03, 136.46 (2C), 135.29, 131.85, 129.87, 129.40, 128.81, 52.73.
10. 2SO] 171.87, 156.85, 149.23, 132.07, 116.65.
11. +, 179].
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13. 2SO] 158.02, 157.74 148.83, 125.16.
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16. 2 requires C, 33.3; H, 2.2; N, 44.7%, M + H, 181).