Secondary acute myeloblastic leukemia with t(16;21)(q24;q22) involving the AML1 gene

Hematology and Cell Therapy

Volumn 38, Issue 2, 1996, Pages 183-186

  Berger, R ^a   Le Coniat, M ^a   Romana, S P ^a   Jonveaux, P ^a,b  

^a CNRS   (France)

^b CHU NANCY BRABOIS   (France)

Author keywords

AML1 gene; secondary leukemia; t(16; 21); translocation

Indexed keywords

ACUTE GRANULOCYTIC LEUKEMIA; ADULT; ARTICLE; CASE REPORT; CHROMOSOME TRANSLOCATION 16; CHROMOSOME TRANSLOCATION 21; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; HUMAN; HUMAN CELL; HUMAN TISSUE;

EID: 0030048518     PISSN: 14302772     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00282-996-0183-9     Document Type: Article

References (36)

1. Baer MR, Sreekantajah C, Jani Sait SN, Sawyer AM, Block AMW, Sandberg AA, Preisler HD (1990) Cytogenetic study of maturing granulocytes in bone marrow of patients with acute myelogenous leukemia. Leukemia 4: 297-301
2. Berger R, Bernheim A, Le Coniat M, Vecchione D, Pacot A, Daniel M-T, Flandrin G (1986) Abnormalities of the short arm of chromosome 12 in acute nonlymphocytic leukemia and dysmyelopoietic syndrome. Cancer Genet Cytogenet 19 : 281-289
3. Bernstein R, Pinto MR, Wallace C, Penfold G, Mendelow B (1984) The incidence, type, and subsequent evolution of 14 variant Ph1 translocations in 180 South African patients with Phi-positive chronic myeloid leukemia. Cancer Genet Cytogenet 12 : 225-238
4. Bitter MA, Neilly ME, Le Beau MM, Pearson MG, Rowley JD (1985) Rearrangements of chromosome 3 involving bands 3q21 and 3q26 are associated with normal or elevated platelet counts in acute nonlymphocytic leukemia. Blood 66 : 1362-1370
5. Carrol AJ, Castleberry RP, Prchal JT, Finley WH (1985) Translocation (6;9)(p23;q34) in acute nonlymphocytic leukemia: three new cases. Cancer Genet Cytogenet 18 : 303-306
6. Chumakov I, Rigault P, Guillou S, Ougen P, Billaut A, Guasconi G, Gervy P, LeGall I, Soularue P, Grinas L, Bougueleret L, BellaneChantelot C, Lacroix B, Barillot E, Gesnouin P, Pook S, Vaysseix G, Frelat G, Schmilz A, Sambucy J-L, Boasch A, Weissenbach J, Vignal A, Riethman H, Cox D, Patterson D, Gardiner K, Hattori M, Sasaki Y, Ichikawa H, Ohki M, Le Paslier D, Heilig R, Antonorakis S, Cohen D (1992) Continuum of overlapping clones spanning the entire chromosome 21q. Nature 359 : 380-387
7. Dube I, Dixon J, Beckett T, Grossman A, Weinstein M, Benn P, McKeithan T, Norman C, Pinkerton P (1989) Location of breakpoints within the major breakpoint cluster region (bcr) in 33 patients with bcr rearrangement-positive chronic myeloid leukemia (CML) with complex or absent Philadelphia chromosomes. Genes Chromosom Cancer 1 : 106-111
8. Felix CA, Winick NJ, Negrini M, Bowman WP, Croce CM, Lange BJ (1993) Common region of ALL-1 gene is disrupted in epipodophyllotoxin-related secondary acute myeloid leukemia. Cancer Res 53 : 2954-2956
9. Horiike S, Tanikawi M, Misawa S, Abe T (1988) Chromosome abnormalities and karyotypic evolution in 83 patients with myelodysplastic syndrome and predictive value for prognosis. Cancer 62 : 1129-1138
10. Hunger SP, Taktchuk DC, Amylon MD, Link MP, Carroll AJ, Welborn JL, Willman CL, Cleary ML(1993) HRX involvement in de novo and secondary leukemias with diverse chromosome 11q23 abnormalities. Blood 81: 3197-3203
11. Köller U, Haas OA, Ludwig W-D, Bartram CR, Harbott J, PanzerGrümayer R, Hansen-Hagge T, Ritter J, Creutzig U, Knapp W, Gadner H (1989) Phenotypic and genotypic heterogeneity in infant acute leukemia. II. Acute nonlymphoblastic leukemia. Leukemia 3 : 708-714
12. Larripa I, Labal de Vinuesa M, Bengio R, Slavutsky I (1987) Chromosome studies in human hematologic diseases : II. Myelodysplastic syndromes. Haematologica 72 : 399-403
13. Larson RA, Wernli M, Le Beau MM, Daly KM, Pape LH, Rowley JD, Vardiman JW (1988) Short remission durations in therapyrelated leukemia despite cytogenetic complete responses to highdose cytarabine. Blood 72 : 1333-1339
14. Le Beau MM, Albain KS, Larson RA, Vardiman JW, Davis EM, Blough RR, Golomb HM, Rowley JD (1986) Clinical and cytogenetic correlations in 63 patients with therapy-related myelodysplastic syndromes and acute nonlymphocytic leukemia: further evidence for characteristic abnormalities of chromosomes 5 and 7. J Clin Oncol 4 : 325-345
15. Li Y-S, Hayohe FGJ (1988) Ph1 chromosome positive acute myelomonocytic leukaemia with inverted chromosome 16. Br J Haematol 69 : 576
16. Mitelman F (1991) Catalog of chromosome aberrations in cancer, 4th edn. Wiley-Liss, New York
17. Miniero R, Madon E, Avanzi G-C, Saitta M, Forni M, Ghisolfi G, Coda R, Lista P, Cordero di Montezemolo L, Cattoretti G, Pegoraro L (1987) Unusual cytogenetic, immunophenotypic and histochemical findings in a case of acute megakaryocytic leukemia. Haematologica 72 : 505-510
18. Nucifora G, Birn DJ, Espinosa III R, Erickson P, LeBeau MM, Roulston D, McKeithan TW, Drabkin H, Rowley JD (1993) Involvement of the AML1 gene in the t(3;21) in therapy-related leukemia and in chronic myeloid leukemia in blast crisis. Blood 81 : 2728-2734
19. Oshimura M, Hayata I, Kakati S, Sandberg AA (1976) Chromosomes and causation of human cancer and leukemia. XVII. Banding studies in acute myeloblastic leukemia (AML). Cancer 38 : 748-761
20. Pedersen-Bjergaard J, Philip P (1991) Balanced translocations involving bands 11q23 and 21q22 are highly characteristic of myelodysplasia and leukemia following therapy with cytostatic agents argeting at DNA-topoisomerase II. Blood 78 : 1147-1148
21. Pedersen-Bjergaard J, Johansson B, Philip P (1994) Translocation (3;21)(q26;q22) in therapy-related myelodysplasia following drugs targeting DNA-topoisomerase II combined with alkylating agents, and in myeloproliferative disorders undergoing spontaneous leukemic transformation. Cancer Genet Cytogenet 76 : 50-55
22. Pettenati MJ, McNay JW, Chauvenet AR (1989) Translocation of the MOS gene in a rare t(8;16) associated with acute myeloblastic leukemia and Down syndrome. Cancer Genet Cytogenet 37 : 221-227
23. Prieto F, Carbonell F, Badia L, Castel V, Perez Sirvent ML (1985) Citogenetica en el estudio de los sindromes mielodosplasicos. Sangre 30 : 669-679
24. Prigogina EL, Fleischman EW, Puchkova GP, Mayakova SA, Volkova MA, Protasova AK, Frenkel MA (1986) Chromosomes in acute nonlymphocytic leukemia. Hum Genet 73 : 137-146
25. Quesnel B, Kantarjian H, Pedersen-Bjergaard J, Brault P, Estey E, Lai JL, Tilly H, Stoppa AM, Archambault E, Harousseau JL, Bauters F, Fenaux P (1993) Therapy-related acute myeloid leukemia with t(8;21), inv (16) and t(8.16). A report of 25 cases and review of the literature. J Clin Oncol 11 : 2370-2379
26. Raimondi SC, Kalwinsky DK, Hayashi Y, Behm FG, Mirro J Jr, Williams DL (1989) Cytogenetics of childhood acute nonlymphocytic leukemia. Cancer Genet Cytogenet 40 : 13-27
27. Romans SP, Le Coniat M, Berger R (1994) t(12;21) : A new recurrent translocation in acute lymphoblastic leukemia. Genes Chromosom Cancer 9 : 186-191
28. Sandberg AA, Morgan R, Berger C, Kaiser-McCaw Hecht B, Hecht F (1984) Chromosome analysis in hematologic disorders. The leukemias. Am J Med 76 : 971-982
29. Sandoval C, Pui C-H, Bowman LC, Heaton D, Hurwitz CA, Raimondi SC, Behm FG, Head DR (1993) Secondary acute myeloid leukemia in children previously treated with alkylating agents, intercalating topoisomerase II inhibitors, and irradiation, J Clin Oncol 11 : 1039-1045
30. Shimizu K, Ichikawa H, Tojo A, Kaneko Y, Mseki N, Hayashi Y, Ohira M, Asano S, Ohki M (1993) An ets-related gene, ERG, is rearranged in human myeloid leukemia with t(16;21) chromosomal translocation. Proc Natl Acad Sci USA 90 : 10280-10284
31. Super HJG, McCabe NR, Thirman MJ, Larson RA, LeBeau MM, Pedersen- Bjergaard J, Philip P, Diaz MO, Rowley JD (1993) Rearrangements of the MLL gene in therapy-related acute myeloid leukemia in patients previously treated with agents targeting DNA topoisomerase II. Blood 82 : 3705-3711
32. Swolin B, Weinfeld A, Waldenström J, Westin J (1983) Cytogenetic studies of bone marrow and extramedullary tissues and clinical course during metamorphosis of chronic myelocytic leukemia. Cancer Genet Cytogenet 9 : 197-209
33. Trent JM, Davis JR, Durie BGM (1983) Cytogenetic analysis of leukaemic colonies from acute and chronic myelogenous leukaemia. Br J Cancer 47 : 103-109
34. Whang-Peng J, Lee EC, Kao-Shan CS, Schechter G (1987) Ring chromosome in a case of acute myelomonocytic leukemia : Its significance and a review of the literature. Hematol Pathol 1 : 57-65
35. Whang-Peng J, Young RC, Lee EC, Longo DL, Schechter GP, DeVita VT Jr (1988) Cytogenetic studies in patients with secondary leukemia/dysmyelopoietic syndrome after different treatment modalities. Blood 71 : 403-411
36. Yunis JJ, Rydell RE, Okjen MM, Arnesen MA, Mayer MG, Lobell M (1986) Refined chromosome analysis as an independent prognosis indicator in de novo myelodysplastic syndromes. Blood 67 : 1721-1730