A herpes simplex virus-1 vector containing the rat tyrosine hydroxylase promoter directs cell type-specific expression of beta-galactosidase in cultured rat peripheral neurons

Molecular Brain Research

Volumn 35, Issue 1-2, 1996, Pages 227-236

  Oh, Young J ^a,b   Moffat, Mark ^a   Wong, Shou ^a,c   Ullrey, Donna ^d   Geller, Alfred I ^d   O'Malley, Karen L ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Yonsei University   (South Korea)

^c CytoTherapeutics Inc   (United States)

^d BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

Cell culture; Cell type specific expression; Infection; Tyrosine hydroxylase; X gal cytochemistry

Indexed keywords

BETA GALACTOSIDASE; TYROSINE 3 MONOOXYGENASE;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CYTOCHEMISTRY; EXPRESSION VECTOR; HERPES SIMPLEX VIRUS 1; NERVE CELL CULTURE; NONHUMAN; PERIPHERAL NERVOUS SYSTEM; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; RAT; SPINAL GANGLION; SUPERIOR CERVICAL GANGLION;

ANIMALIA; HERPES; HUMAN HERPESVIRUS 1;

EID: 0030048450     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0169-328X(95)00221-D     Document Type: Article

References (48)

1. Andersen, J.K., Frim, D.M., Isacson, O. and Breakefield, X.O., Herpesvirus-mediated gene delivery into the rat brain: specificity and efficiency of the neuron-specific enolase promoter, Cell. Mol. Neurobiol., 13 (1993) 503-515.
2. Banerjee, S.A., Hoppe, P., Brilliant, M. and Chikaraishi, D.M., 5′ flanking sequences of the rat tyrosine hydroxylase gene target accurate tissue-specific, developmental and transsynaptic expression in transgenic mice, J. Neurosci., 12 (1992) 4460-4467.
3. Banerjee, S.A., Roffler-Tarlov, S., Szabo, M., Frohman, L. and Chikaraishi, D.M., DNA regulatory sequences of the rat tyrosine hydroxylase gene direct correct catecholaminergic cell-type specificity of a human growth hormone reporter in the CNS of transgenic mice causing a dwarf phenotype, Mol. Brain Res., 24 (1994) 89-106.
4. Bjorklund, A. and Lindvall, O., Classical neurotransmitter in the CNS. In A. Bjorklund and T. Hokfelt (Eds.), Handbook of Chemical Neuroanatomy, Mol. Brain Res., Elsevier, Amsterdam, 1984, pp. 55-111.
5. Blum, M., Regulation of neuroendocrine peptide gene expression, Methods Enzymol., 168 (1989) 618-633.
6. Brown, E.R., Coker, III G.T. and O'Malley, K.L., Organization and evolution of the rat tyrosine hydroxylase gene, Biochemistry, 26 (1987) 5208-5212.
7. Cambi, F., Fung, B. and Chikaraishi, D.M., 5′ Flanking DNA sequences direct cell-specific expression of rat tyrosine hydroxylase, J. Neurochem., 53 (1989) 1656-1659.
8. Carrier, A., Devignes, M.D., Renoir, D. and Auffray, C., Chicken tyrosine hydroxylase gene: isolation and functional characterization of the 5′ flanking region, J. Neurochem., 61 (1993) 2215-2224.
9. Carroll, J.M., Kim, K.S., Kim, K.T., Goodman, H.M. and Job, T.H., Effects of second messenger system activation on functional expression of tyrosine hydroxylase fusion gene constructs in neuronal and nonneuronal cells, J. Mol. Neurosci., 3 (1991) 65-74.
10. Chomczynski, P. and Sacchi, N., Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction, Anal. Biochem., 162 (1987) 156-159.
11. Coker, G.T., Vinnedge, L. and O'Malley, K.L., Characterization of rat and human tyrosine hydroxylase genes: Functional expression of both promoters in neuronal and non-neuronal cell types, Biochem. Biophys. Res. Commun., 157 (1988) 1341-1347.
12. Dawson, S.J., Yoon, S.O., Chikaraishi, D.M., Lillycrop, K.A. and Latchman, D., The Oct-2 transcription factor represses tyrosine hydroxylase expression via a heptamer TAATGARAT-like motif in the gene promoter, Nucleic Acids Res., 22 (1994) 1023-1028.
13. During, M., Naegele, J.R., O'Malley, K.L. and Geller, A.I., Long-term behavioral recovery in Parkinsonian rats by an HSV vector expressing tyrosine hydroxylase, Science, 266 (1994) 1399-1403.
14. Fader, D. and Lewis, E.J., Interaction of cyclic AMP and cell-cell contact in the control of tyrosine hydroxylase RNA, Mol. Brain Res., 8 (1990) 25-29.
15. Federoff, H.J., Geller, A.I. and Lu, B., Neuronal specific expression of the human neurofilament L promoter in a HSV-1 vector, Soc. Neurosci. Abstr., 16 (1990) 353.
16. Federoff, H.J., Geschwind, M.D., Geller, A.I. and Kessler, J.A., Expression of nerve growth factor in vivo from a defective herpes simplex virus 1 vector prevents effects of axotomy on sympathetic ganglia, Proc. Natl. Acad. Sci. USA, 89 (1992) 1636-1640.
17. Fung, B., Yoon, S.O. and Chikaraishi, D.M., Sequences that direct rat tyrosine hydroxylase expression, J. Neurochem., 58 (1992) 2044-2052.
18. Gandelman, K.-Y., Coker, G.T., Moffat, M. and O'Malley, K.L., Species and regional differences in the expression of cell-type specific elements at the human and rat tyrosine hydroxylase gene loci, J. Neurochem., 55 (1990) 2149-2152.
19. Gandelman, K.-Y., Harmon, S., Todd, R.D. and O'Malley, K.L., Analysis of the structure and expression of the human dopamine D2A receptor gene, J. Neurochem., 56 (1991) 1024-1029.
20. Geller, A.I. and Breakefield, X.O., A defective HSV-1 vector expresses Escherichia coli β-galactosidase in cultured peripheral neurons, Science, 241 (1988) 1667-1669.
21. Geller, A.I. and Freese, A., Infection of cultured central nervous system neurons with a defective herpes simplex virus 1 vector results in stable expression of Escherichia coli β-galactosidase, Proc. Natl. Acad. Sci. USA, 87 (1990) 1149-1153.
22. Geller, A.I., Keyomarsi, K., Bryan, J. and Pardee, A.B., An efficient deletion mutant packaging system for defective herpes simplex virus vectors: Potential applications to human gene therapy and neuronal physiology, Proc. Natl. Acad. Sci. USA, 87 (1990) 8950-8954.
23. Geller, A.I., During, M.J. and Neve, R.L., Molecular analysis of neuronal physiology by gene transfer into neurons with herpes simplex virus vectors, Trends Neurosci., 14 (1991) 428-432.
24. Gizang-Ginsberg, E. and Ziff, E.B., Nerve growth factor regulates tyrosine hydroxylase gene transcription through a nucleoprotein complex that contains c-Fos, Genes and Devel., 4 (1990) 477-491.
25. Gizang-Ginsberg, E. and Ziff, E.B., Fos family members successively occupy the tyrosine hydroxylase gene AP-1 site after nerve growth factor or epidermal growth factor stimulation and can repress transcription, Mol. Endocrinol., 8 (1994) 249-262.
26. Grima, B., Lamouroux, A., Blanot, F., Biguet, N.F. and Mallet J., Complete coding sequence of rat tyrosine hydroxylase mRNA, Proc. Natl. Acad. Sci. USA, 82 (1985) 617-621.
27. Higuchi, R., Rapid, efficient DNA extraction for PCR from cells or blood, Amplifications, 2 (1989) 1-3.
28. Imagawa, M., Chiu, R. and Karin, M., Transcription factor AP-2 mediates induction by two different signal-transduction pathways: Protein kinase C and cAMP, Cell, 51 (1987) 251-260.
29. Jones, K.A., Kadonaga, J.T., Luciw, P.A. and Tjian, R., Activation of the AIDS retrovirus promoter by the cellular transcription factor, Sp1, Science, 232 (1986) 755-759.
30. Kalnins, A., Otto, K., Ruether, U. and Mueller-Hill, B., Sequence of the LacZ gene of Escherichia coli, EMBO J., 2 (1983) 593-597.
31. Kaner, B.J., Baird, A., Mansukhani, A., Basdilico, C., Summers, B.D., Florkiewicz, R.Z. and Hajjar, D.D., Fibroblast growth factor receptor is a portal of cellular entry for herpes simplex virus type 1, Science, 248 (1990) 1410-1413.
32. Kaplitt, M.G., Kwong, A.D., Kleopoulos, S.P., Mobbs, C.V, Rabkin, S.D. and Pfaff, D.W., Preproenkephalin promoter yields region-specific and long-term expression in adult brain after direct in vivo gene transfer via a defective herpes simplex viral vector, Proc. Natl. Acad. Sci. USA, 91 (1994) 8979-8983.
33. Kim, K.-S., Lee, M.K., Carroll, J. and Joh, T.H., Both the basal and inducible transcription of the tyrosine hydroxylase gene are dependent upon a cAMP response element, J. Biol. Chem., 268 (1993) 15689-15695.
34. Kraner, S.D., Chong, J.A., Tsay, H.J. and Mandel, G., Silencing the type II sodium channel gene: a model for neural-specific gene regulation, Neuron, 9 (1992) 37-44.
35. Krug, M.S. and Berger, S.L., First strand cDNA synthesis primed with oligo(dT), Methods Enzymol., 152 (1987) 316-325.
36. Li, L., Suzuki, T., Mori, N. and Greengard, P., Identification of a functional silencer element involved in neuron-specific expression of the synapsin I gene, Proc. Natl. Acad. Sci. USA, 90 (1993) 1460-1464.
37. Liu, J., Nichol, M.C., Wong, S.C., Merlie, J.P. and O'Malley, K.L., Increasing lengths of tryosine hydroxylase promoter sequence increases cell type specific expression in vivo, Soc. Neurosi. Abstr., 20 (1994) 633.
38. Montminy, M.R., Sevarino, K.A., Wagner, J.A., Mandel, G. and Goodman, R.H., Identification of a cyclic-AMP-responsive element within the rat somatostatin gene, Proc. Natl. Acad. Sci. USA, 83 (1986) 6682-6686.
39. + channel genes binds a factor present in nonneuronal cells but not in neuronal cells, Neuron, 9 (1992) 45-54.
40. Nguyen, T.D., Southern blot analysis of polymerase chain reaction products on acrylamide gels, Biotechniques, 1 (1989) 238-240.
41. Palmiter, R.D. and Brinster, R., Transgenic mice, Cell, 41 (1985) 343-345.
42. Price, J. and Mudge, A.W., A subpopulation of rat dorsal root ganglion neurons is catecholaminergic, Nature, 301 (1983) 242-243.
43. Schoenherr, C.J. and Anderson, D.J., The neuron-restrictive silencer factor (NRSF): a coordinate repressor of multiple neuron-specific genes, Science, 267 (1995) 1360-1363.
44. Shieh, M.T., WuDunn, D., Montgomery, R.I., Esko, J.D. and Spear, P.G., Cell surface receptors for herpes simplex virus are heparan sulfate proteoglycan, J. Cell Biol., 116 (1992) 1273-1281.
45. Wilcox, C.L., Smith, R.L., Freed, C.R. and Johnson, Jr. E.M., Nerve growth factor-dependence of herpes simplex virus latency in peripheral sympathetic and sensory neurons in vitro, J. Neurosci., 10 (1990) 1268-1275.
46. Wong, S.C., Moffat, M. and O'Malley, K.L., Sequences distal to the AP1/E box motif are involved in the cell tissue-specific expression of the rat tyrosine hydroxylase gene, J. Neurochem., 62 (1994) 1691-1697.
47. Yoon, S.O. and Chikaraishi, D.M., Tissue-specific transcription of the rat tyrosine hydroxylase gene requires synergy between an AP-1 motif and an overlapping E box-containing dyad, Neuron, 9 (1992) 55-67.
48. Zenke, M., Grunstrom, T., Matthes, H., Wintzerith, M., Schatz, C., Wildeman, A. and Chambon, P., Multiple sequence motifs are required for SV 40 enhancer function, EMBO J., 5 (1986) 387-397.