Vitamin E, retinyl palmitate, and protein in rhesus monkey retina and retinal pigment epithelium-choroid

Investigative Ophthalmology and Visual Science

Volumn 37, Issue 1, 1996, Pages 47-60

  Crabtree, Donald V ^a,b   Adler, Alice J ^a,b   Snodderly, D Max ^a,b  

^a SCHEPENS EYE RESEARCH INSTITUTE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

macular degeneration; monkey; retina; retinyl palmitate; vitamin E

Indexed keywords

ALPHA TOCOPHEROL; ASCORBIC ACID; BETA TOCOPHEROL; DELTA TOCOPHEROL; GAMMA TOCOPHEROL; PROTEIN; RETINOL PALMITATE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CHOROID; DIETARY INTAKE; NONHUMAN; ORAL DRUG ADMINISTRATION; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN CONTENT; RETINA MACULA DEGENERATION; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; RHESUS MONKEY; TISSUE DISTRIBUTION; VITAMIN BLOOD LEVEL; VITAMIN INTAKE;

ANIMALS; CHOROID; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; EYE PROTEINS; FEMALE; HUMANS; MACACA MULATTA; MALE; PIGMENT EPITHELIUM OF EYE; RETINA; VITAMIN A; VITAMIN E;

EID: 0030048411     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (61)

1. Packer L, Landvik S. Vitamin E in Biological Systems. Adv Exp Med Biol. 1990;264:93-103.
2. Handelman GJ, Dratz EA. The role of antioxidants in the retina and retinal pigment epithelium and the nature of prooxidant-induced damage. Adv Free Radical Biol Med. 1986;2:1-89.
3. Burton GW, Ingold KU. Autoxidation of biological molecules: 1: The antioxidant activity of vitamin E and related chain-breaking phenolic antioxidants in vitro. J Am Chem Soc. 1981;103:6472-6477.
4. Aranda FJ, Coutinho A, Berberan-Santos MN, Prieto MJE, Gómez-Fernández JC. Fluorescence study of the location and dynamics of α-tocopherol in phospholipid vesicles. Biochim Biophys Acta. 1989;985:26-32.
5. Drevon CA. Absorption, transport and metabolism of vitamin E. Free Radic Res Comms. 1991;14:229-246.
6. Traber MG, Kayden HJ. Preferential incorporation of α-tocopherol vs γ-tocopherol in human lipoproteins. Am J Clin Nutr. 1989;49:517-526.
7. Catignani GL, Bieri JG. Rat liver α-tocopherol binding protein. Biochim Biophys Acta. 1977;497:349-357.
8. Century B, Horwitt MK. Biological availability of various forms of vitamin E with respect to different indices of deficiency. Fed Proc, Fed Am Soc Exp Biol. 1965;24:906-911.
9. Chow CK. Vitamin E and blood. World Rev Nutr Diet. 1985;45:133-166.
10. Alvarez RA, Liou GI, Fong S-L, Bridges CDB. Levels of α- and γ-tocopherol in human eyes: Evaluation of the possible role of IRBP in intraocular α-tocopherol transport. Am J Clin Nutr. 1987;46:481-487.
11. Handelman GJ, Machlin LJ, Fitch K, Weiter JJ, Dratz EA. Oral α-tocopherol supplements decrease plasma γ-tocopherol levels in humans. J Nutr. 1985;115:807-813.
12. Mukai K, Fukuda K, Ishizu K. Stopped-flow investigation of antioxidant activity of tocopherols: Finding of new tocopherol derivatives having higher antioxidant activity than α-tocopherol. Chem Phys Lipids. 1988; 46:31-36.
13. Fliesler SJ, Anderson RE. Chemistry and metabolism of lipids in the vertebrate retina. Prog Lipid Res. 1983;22:79-131.
14. Futterman S, Downer JL, Hendrickson A. Effect of essential fatty acid deficiency on the fatty acid composition, morphology, and electroretinographic response of the retina. Invest Ophthalmol. 1971;10:151-156.
15. Ahmed J, Braun RD, Dun R Jr, Linsenmeier RA. Oxygen distribution in the macaque retina. Invest Ophthalmol Vis Sci. 1993;34:516-521.
16. West S, Vitale S, Hallfrisch J, et al. Are Antioxidants or supplements protective for age-related macular degeneration? Arch Ophthalmol. 1994;112:222-227.
17. Eye Disease Case-Control Study Group. Antioxidant status and neovascular age-related macular degeneration. Arch Ophthalmol. 1993;111:104-109.
18. Ryan SJ. Subretinal neovascularization: Natural history of an experimental model. Arch Ophthalmol. 1982;100:1804-1809.
19. Organisciak DT, Berman ER, Wang H-M, Feeney-Burns L. Vitamin E in human neural retina and retinal pigment epithelium: Effect of age. Curr Eye Res. 1987;6:1051-1055.
20. Organisciak DT, Feeney-Burns L, Bridges CDB. On the measurement of vitamin E in human ocular tissues. Letter. Curr Eye Res. 1987;6:1487-1488.
21. Nielsen JC, Naash MI, Anderson RE. The regional distribution of vitamins E and C in mature and premature human retinas. Invest Ophthalmol Vis Sci. 1988;29:22-26.
22. Farber DB, Flannery JG, Lolley RN, Bok D. Distribution patterns of photoreceptors, protein, and cyclic nucleotides in the human retina. Invest Ophthalmol Vis Sci. 1985;26:1558-1568.
23. Bridges CDB, Alvarez RA, Fong S-L. Vitamin A in human eyes: Amount, distribution, and composition. Invest Ophthalmol Vis Sci. 1982;22:706-714.
24. Lehmann J, Martin HL, Lashley EL, Marshall MW, Judd JT. Vitamin E in foods from high and low linolcic acid diets. J Am Diet Assoc. 1986;86:1208-1216.
25. Romieu I, Stampfer MJ, Stryker WS, et al. Food predictors of plasma beta-carotene and alpha-tocopherol: Validation of a food frequency questionnaire. Am J Epidermiol. 1990;131:864-876.
26. Crabtree DV, Adler AJ, Snodderly DM. Radial distribution of tocopherols in rhesus monkey retina and retinal pigment epithelium-choroid. Invest Ophthalmol Vis Sci. 1996;37:61-76.
27. Frei B, England L, Ames BN. Ascorbate is an outstanding antioxidant in human blood plasma. Proc Natl Acad Sci USA. 1989;86:6377-6381.
28. Craft NE, Brown ED, Smith JC Jr. Effects of storage and handling conditions on concentrations of individual carotenoids, retinol, and tocopherol in plasma. Clin Chem. 1988;34:44-48.
29. Snodderly DM, Weinbaus RS, Choi JC. Neural - vascular relationships in central retina of macaque monkeys (Macaca fascicularis). J Neurosci. 1992;12:1169-1193.
30. Hunt DF, Organisciak DT, Wang HM, Wu RLC. α-Tocopherol in the developing rat retina: A high pressure liquid chromatographic analysis. Curr Eye Res. 1984;3:1281-1288.
31. Hatam LJ, Kayden HJ. A high-performance liquid chromatographic method for the determination of tocopherol in plasma and cellular elements of the blood. J Lipid Res. 1979;20:639-645.
32. Tan B, Brzuskiewicz L. Separation of tocopherol and tocotrienol isomers using normal- and reverse-phase liquid chromatography. Anal Biochem. 1989;180:368-373.
33. Lovelady HG. Separation of β- and γ-tocopherols in the presence of α- and δ-tocopherols and vitamin A acetate. J Chromatogr. 1973;78:449-452.
34. Budavari S, ed. The Merck Index. 11th ed. Rahway, NJ: Merck & Co.; 1989:1576.
35. Alvarez RA, Bridges CDB, Fong S-L. High-pressure liquid chromatography of fatty acid esters of retinol isomers. Invest Ophthalmol Vis Sci. 1981;20:304-313.
36. Sowell AL, Huff DL, Yeager PR, Caudill SP, Gunter EW. Retinol, α-tocopherol, lutein/zeaxanthin, β-cryptoxanthin, lycopene, α-carotene, trans-β-carotene, and four retinyl esters in serum determined simultaneously by reversed-phase HPLC with multiwavelength detection. Clin Chem. 1994;40:411-416.
37. Lowry OH, Rosenbrough NJ, Farr AL, Randall RJ. Protein measurement with the folin-phenol reagent. J Biol Chem. 1951;193:265-275.
38. Bligh EG, Dyer WJ. A rapid method of total lipid extraction and purification. Can J Biochem Physiol. 1959;37:911-917.
39. Bieri JG, Poukka Evarts R. Gamma tocopherol: Metabolism, biological activity and significance in human vitamin E nutrition. Am J Clin Nutr. 1974;27:980-986.
40. Slater TF, Sawyer BC. The stimulatory effects of carbon tetrachloride and other halogenoalkanes on peroxidative reactions in rat liver fractions in vitro. Biochem J. 1971;123:805-814.
41. Burfield DR, Goh EH, Ong EH, Smithers RH. Storage and decomposition of chloroform. Gazzetta Chimica Italiana. 1983;113:841-843.
42. Price DL, Martin LJ, Sisodia SS, et al. Aged non-human primates: An animal model of age-associated neurodegenerative disease. Brain Pathol 1991;1:287-296.
43. Hayes KC. Retinal degeneration in monkeys induced by deficiencies of vitamin E or A. Invest Ophthalmol. 1974;13:499-510.
44. Stephens RJ, Negi DS, Short SM, van Kuijk FJGM, Dratz EA, Thomas DW. Vitamin E distribution in ocular tissues following long-term dietary depletion and supplementation as determined by microdissection and gas chromatography-mass spectrometry. Exp Eye Res. 1988;47:237-245.
45. Bhat R. Serum, retinal, choroidal vitreal vitamin E concentrations in human infants. Pediatrics. 1986; 78:866-870.
46. Bhat R, Tonse R, Barrada A, Evans M. Disposition of vitamin E in the eye. Pediatr Res. 1987;22:16-20.
47. Chow FI, Omaye ST. Use of antioxidants in the analysis of vitamins A and E in mammalian plasma by high performance liquid chromatography. Lipids. 1983; 18:837-841.
48. Farnsworth CC, Dratz EA. Oxidative damage of retinal rod outer segment membranes and the role of vitamin E. Biochim Biophys Acta. 1976;443:556-570.
49. Fry JM, Smith GM, McGrath MC, Speijers EJ, Allen JG. Plasma and tissue concentrations of α-tocopherol during vitamin E depletion in sheep. Br J Nutr. 1993;69:225-232.
50. Kirk RE. Experimental Design: Procedures for the Behavioral Sciences. Moriterey, CA: Brooks/Cole Publishing; 1982:134-165.
51. Vatassery GT, Angerhofer CK, Knox CA. Effect of age on vitamin E concentrations in various regions of the brain and a few selected peripheral tissues of the rat, and on the uptake of radioactive vitamin E by various regions of rat brain. J Neurochem. 1984;43:409-412.
52. Harman D. The aging process. Proc Natl Acad Sci USA. 1981;78:7124-7128.
53. Dawson WW, Ulshafer RJ, Engel HM, Hope GM, Kessler MJ. Macular disease in related rhesus monkeys. Doc Ophthalmol. 1989;71:253-263.
54. Snodderly DM, Handelman GJ, Adler AJ. Distribution of individual macular pigment carotenoids in central retina of macaque and squirrel monkeys. Invest Ophthalmol Vis Sci. 1991;32:268-279.
55. Snodderly DM, Auran JD, Delori FC. The macular pigment: II: Spatial distribution in primate retinas. Invest Ophthalmol Vis Sci. 1984;25:674-685.
56. Handelman GJ, Snodderly DM, Krinsky NI, Russett MD, Adler AJ. Biological control of primate macular pigment. Invest Ophthalmol Vis Sci. 1991;32:257-267.
57. Burton GW, Ingold KU. β-Carotene: an unusual type of lipid antioxidant. Science. 1984;224:569-573.
58. Sheraidah G, Steinmetz R, Maguire J, Pauleikhoff D, Marshall J, Bird AC. Correlation between lipids extracted from Bruch's membrane and age. Ophthalmology. 1993;100:47-51.
59. Dilley RA, McConnell DG. Alpha-tocopherol in the retinal outer segment of bovine eyes. J Membr Biol. 1970;2:317-323.
60. Hayes KC. Pathophysiology of vitamin E deficiency in monkeys. Am J Clin Nutr. 1974;27:1130-1140.
61. Ausman LM, Hayes KC. Vitamin E deficiency anemia in Old and New World monkeys. Am J Clin Nutr. 1974;27:1141-1151.