Neonatal sensory denervation affects the expression of endothelial peptides in the adult rat pulmonary artery: More cells contain substance P and less contain endothelin

Endothelium: Journal of Endothelial Cell Research

Volumn 4, Issue 1, 1996, Pages 71-76

  Milner, Pamela ^a   Loesch, Andrzej ^a   Burnstock, Geoffrey ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Endothelin; Endothelium; Plasticity; Sensory denervation; Substance P; Vasopressin

Indexed keywords

ARGIPRESSIN; CAPSAICIN; ENDOTHELIN; SUBSTANCE P; VASOACTIVE AGENT;

ANIMAL EXPERIMENT; ANTIBODY LABELING; ARTERY ENDOTHELIUM; ARTICLE; BLOOD VESSEL TONE; CONTROLLED STUDY; DENERVATION; ENDOTHELIUM CELL; INNERVATION; MALE; NEWBORN; NONHUMAN; PEPTIDE SYNTHESIS; PULMONARY ARTERY; RAT; SENSORY NERVE; VASCULAR ENDOTHELIUM; VASCULAR SMOOTH MUSCLE;

EID: 0030048144     PISSN: 10623329     EISSN: None     Source Type: Journal    
DOI: 10.3109/10623329609024683     Document Type: Article

References (25)

1. Burnstock, G. and Griffith, S. G. (1988) Nonadrenergic innervation of blood vessels. Vols I & II. CRC Press, Boca Raton, Florida.
2. Davies, P. F. and Tripathi, S. C. (1993) Mechanical stress mechanisms and the cell. An endothelial paradigm. Circ. Res., 72, 239-245.
3. De Nucci, G., Thomas, R., D'Orleans-Juste, P., Antunes, E., Walder, C., Warner, T. D. and Vane, J. R. (1988) Pressor effects of circulating endothelin are limited by its removal in the pulmonary circulation and by the release of prostacyclin and endothelium-derived relaxing factor. Proc. Natl. Acad. Sci. USA, 85, 9797-9800.
4. Furchgott, R. F. (1984) The role of endothelium in the responses of vascular smooth muscle to drugs. Ann. Rev. Pharmac. Toxicol., 24, 175-197.
5. Lincoln, J., Loesch, A. and Burnstock, G. (1990) Localization of vasopressin, serotonin and angiotensin II in endothelial cells of the renal and mesenteric arteries of the rat. Cell Tissue Res., 259, 341-344.
6. Loesch, A. and Burnstock, G. (1988) Ultrastructural localisation of serotonin and substance P in vascular endothelial cells of rat femoral and mesenteric arteries. Anal. Embryol., 178, 137-142.
7. Loesch, A., Maynard, K. I. and Burnstock, G. (1992) Calcitonin gene-related peptide- and neuropeptide Y-like immunoreactivity in endothelial cells after long-term stimulation of perivascular nerves. Neuroscience, 48, 723-726.
8. Maggi, C. A. and Meli, A. (1988) The sensory-efferent function of capsaicin-sensitive sensory neurons. Gen. Pharmacol., 19, 1-43.
9. Mangiarua, E. I. and Bevan, R. D. (1986) Altered endothelium-mediated relaxation after denervation of growing rabbit ear artery. Eur. J. Pharmacol., 122, 149-152.
10. Milner, P., Bodin, P. and Burnstock, G. Neonatal guanethidine sympathectomy suppresses flow-induced release of ATP and endothelin from endothelial cells isolated from the adult rat aorta. (submitted).
11. Milner, P., Bodin, P., Loesch, A. and Burnstock, G. (1992) Increased shear stress leads to differential release of endothelin and ATP from isolated endothelial cells from 4-and 12-month-old male rabbit aorta. J. Vasc. Res., 29, 420-425.
12. Milner, P., Bodin, P., Loesch, A. and Burnstock, G. (1995) Interactions between sensory perivascular nerves and the endothelium in brain microvessels. Int. J. Microvasc., 15, 1-9.
13. Milner, P., Kirkpatrick, K. A., Ralevic, V., Toothill, V. J., Pearson, J. D. and Burnstock, G. (1990) Endothelial cells cultured from human umbilical vein release ATP, substance P and acetylcholine in response to altered shear stress. Proc. R. Soc. Series B., 241, 245-248.
14. Milner, P., Ralevic, V., Hopwood, A. M., Fehér, E., Lincoln, J., Kirkpatrick, P. and Burnstock, G. (1989) Ultrastructural localisation of substance P and choline acetyltransferase in endothelial cells of rat coronary artery and release of substance P and acetylcholine during hypoxia. Experientia, 45, 121-125.
15. Poole, J. C. F., Saunders, A. G. and Florey, H. W. (1958) The regeneration of aortic endothelium. J. Pathol. Bacteriol., 75, 133-143.
16. Ralevic, V. and Burnstock, G. (1993) Neural-Endothelial Interactions in the Control of Local Vascular Tone. RG Landes Co., Austin, pp117.
17. Ralevic, V., Milner, P. and Burnstock, G. (1995) Augmented flow-induced endothelin release from the rat mesenteric arterial bed after long-term sympathectomy. Endothelium, 3, 67-73.
18. Ralevic, V., Milner, P., Hudlická, O., Kristek, F. and Burnstock, G. (1990) Substance P is released from endothelial cells of normal and capsaicin-treated rat hindlimb vasculature, in vitro, by increased flow. Circ. Res., 66, 1178-1183.
19. Scott, T. M., Drodge, K. H. and Foote, J. (1992) Peptidergic nerve involvement in the control of endothelium-dependent vascular relaxation. Artery, 19, 211-224.
20. Shetty, S. S., Okada, T., Webb, R. L., DelGrande, D. and Lappe, R. W. (1993) Functionally distinct endothelin B receptors in vascular endothelium and smooth muscle. Biochem. Biophys. Res. Commun., 191, 459-464.
21. 125I-Bolton-Hunter substance P binding to dog carotid arteries. Eur. J. Pharmacol., 134, 35-43.
22. Tasaka, K. and Kitazumi, K. (1994) The control of endothelin-1 secretion. Gen. Pharmacol., 25, 1059-1069.
23. Tomlinson, A., Van Vlijmen, H., Loesch, A. and Burnstock, G. (1991) An immunohistochemical study of endothelial cell heterogeneity in the rat: observations in "en face" Häutchen preparations. Cell Tissue Res., 263, 173-181.
24. Warner, T. D., Mitchell, J. A., De Nucci, G. and Vane, J. R. (1989) Endothelin-1 and endothelin-3 release EDRF from isolated perfused arterial vessels of the rat and rabbit. J. Cardiovasc. Pharmacol., 13, S85-S88.
25. Yanagisawa, M., Kurihara, H., Kimura, S., Tomobe, Y., Kobayashi, M., Mitsui, Y., Yazaki, Y., Goto, K. and Masaki, T. (1988) A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature, 332, 411-415.