Influence of regional differences in ETA and ETB receptor subtype proportions on endothelin-1-induced contractions in porcine isolated trachea and bronchus

British Journal of Pharmacology

Volumn 117, Issue 4, 1996, Pages 736-742

  Goldie, Roy G ^a   D'Aprile, Angela C ^a   Cvetkovski, Robert ^a   Rigby, Paul J ^a   Henry, Peter J ^a  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

Airway smooth muscle; Endothelin 1; ETA and ETB receptors; Porcine bronchus and trachea

Indexed keywords

CYCLO(DEXTRO TRYPTOPHYL DEXTRO ASPARTYLPROLYL DEXTRO VALYLLEUCYL); ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; ENDOTHELIN B RECEPTOR; N (2,6 DIMETHYLPIPERIDINOCARBONYL) 4 METHYLLEUCYL DEXTRO (1 METHOXYCARBONYLTRYPTOPHANYL) DEXTRO NORLEUCINE; RECEPTOR SUBTYPE; SARAFOTOXIN S6C;

ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BINDING SITE; BRONCHUS; BRONCHUS MUSCLE; MALE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR DENSITY; SMOOTH MUSCLE CONTRACTION; TRACHEA; TRACHEA MUSCLE;

ANIMALS; BRONCHI; ENDOTHELINS; IODINE RADIOISOTOPES; KINETICS; MALE; MUSCLE CONTRACTION; RADIOLIGAND ASSAY; RECEPTOR, ENDOTHELIN A; RECEPTOR, ENDOTHELIN B; RECEPTORS, ENDOTHELIN; SWINE; TRACHEA;

EID: 0030047452     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1476-5381.1996.tb15252.x     Document Type: Article

References (23)

1. B receptors mediating contractions induced by endothelin-1 or IRL 1620 in guinea-pig isolated airways: effects of BQ-123, FR139317 or PD 145065. Br. J. Pharmacol., 111, 1009-1016.
2. GOLDIE, R.G., D'APRILE, A.C., SELF, G.J., RIGBY, P.J. & HENRY, P.J. (1996). The distribution and density of receptor subtypes for endothelin-1 in peripheral lung. Br. J. Pharmacol., 117, 729-735.
3. A) receptors in ovine airway smooth muscle and their mediation of ET-1-induced contraction. Br. J. Pharmacol., 112, 749-756.
4. GOLDIE, R.G., HENRY, P.J., KNOTT, P.G., SELF, G.J., LUTTMANN, M.A & HAY, D.W.P. (1995). Endothelin-1 receptor density, distribution and function in human isolated asthmatic airways. Am. J. Respir. Crit. Care Med., 152, 1653-1658.
5. HAY, D.W.P. (1992). Pharmacological evidence for distinct endothelin receptors in guinea-pig bronchus and aorta. Br. J. Pharmacol., 106, 759-761.
6. HAY, D.W.P., HENRY, P.J. & GOLDIE, R.G. (1993a). Endothelin and the respiratory system. Trends Pharmacol. Sci., 14, 29-32.
7. HAY, D.W.P., LUTTMANM, M.A., HUBBARD, W.C. & UNDEM, B.J. (1993b). Endothelin receptor subtypes in human and guinea-pig pulmonary tissues. Br. J. Pharmacol., 110, 1175-1183.
8. B receptors and multiple signal transduction systems. Br. J. Pharmacol., 110, 435-441.
9. HENRY, P.J. & GOLDIE, R.G. (1994). ETB but not ETA receptor-mediated contractions to endothelin-1 attenuated by respiratory tract viral infection in mouse airways. Br. J. Pharmacol., 112, 1188-1194.
10. 2-adrenoceptors in mouse trachea and lung: a quantitative autoradiographic study. Br. J. Pharmacol., 99, 136-144.
11. HENRY, P.J., RIGBY, P.J., SELF, G.J., PREUSS, J.M. & GOLDIE, R.G. (1990b). Relationship between endothelin-l binding site densities and constrictor activities in human and animal airway smooth muscle. Br. J. Pharmacol., 100, 786-792.
12. HISLOP, A.A., ZHAO, Y.D., SPRINGALL, D.R., POLAK, J.M. & HAWORTH, S.G. (1995). Postnatal changes in endothelin-1 binding in porcine pulmonary vessels and airways. Am. J. Respir. Cell Mol. Biol., 12, 557-566.
13. A receptor. Life Sci., 50, 247-255.
14. B receptors on single smooth muscle cells cooperate in mediating guinea-pig tracheal contraction. Am. J. Physiol., 266, L113-L124.
15. KIZAWA, Y., NAKAJIMA, Y., NAKANO, J., UNO, H., SANO, M. & MURAKAMI, H. (1994). Pharmacological profiles of contractile endothelin receptors in guinea-pig hilar bronchus. Receptor, 4, 269-276.
16. MAGGI C.A., GIULIANI, S., PATACCHINI, R., SANTICIOLI, P., GIACHETTI, A. & MELI, A. (1990). Further studies on the response of the guinea-pig isolated bronchus to endothelins and sarafotoxin S6b. Eur. J. Pharmacol., 176, 1-9.
17. MARSAULT, R , VIGNE, P., BREITTMAYER, J.P. & FRELIN, C. (1991). Kinetics of vasoconstrictor action of endothelins. Am. J. Physiol., 261, (Cell Physiol. 30), C986-C993.
18. 1,3,11,15]ET-1. Biochem. Biophys. Res. Commun., 182, 144-150.
19. UCHIDA, Y., NINOMIYA, H., SAOTOME, M., NOMURA, A., OHTSUKA, M., YANAGISAWA, M., GOTO, K., MASAKI, T. & HASEGAWA, S. (1988). Endothelin, a novel vasoconstrictor peptide, as potent bronchoconstrictor. Eur. J. Pharmacol., 154, 227-228.
20. 125I]-endothelin-1 binding data. Life Sci., 51, 1869-1876.
21. WALLENSTEIN, S., ZUCKER, C.L. & FLEISS, J.L. (1980). Some statistical methods useful in circulation research. Cir. Res., 47, 1-9.
22. WILLIAMS, D.L. Jr., JONES, K.L., PETTIBONE, D.J., LIS, E.V. & CLINESCHMIDT, B.V. (1991). Sarafotoxin S6c; an agonist which distinguishes between endothelin receptor subtypes. Biochem. Biophys. Res. Commun., 175, 556-561.
23. B receptors mediating tracheal smooth muscle contraction. Biochem. Biophys. Res. Commun., 207, 668-674.