Regulated, stable expression and nuclear presence of reovirus double-stranded RNA-binding protein σ3 in HeLa cells

Journal of Virology

Volumn 70, Issue 6, 1996, Pages 3497-3501

  Yue, Zhenyu ^a,b   Shatkin, Aaron J ^b  

^a RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^b RUTGERS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAPSID PROTEIN; DOUBLE STRANDED RNA; RNA BINDING PROTEIN;

ARTICLE; CONTROLLED STUDY; HELA CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; REOVIRUS; VIRUS CAPSID; VIRUS CELL INTERACTION; VIRUS EXPRESSION; VIRUS GENOME; VIRUS PATHOGENESIS; VIRUS REPLICATION;

AMINO ACID SEQUENCE; CAPSID PROTEINS; CELL NUCLEUS; HELA CELLS; HUMANS; MOLECULAR SEQUENCE DATA; REOVIRIDAE; RNA, DOUBLE-STRANDED; RNA-BINDING PROTEINS; VIRAL PROTEINS;

EID: 0030047418     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. Ahmed, R., and B. N. Fields. 1982. Role of the S4 gene in the establishment of persistent reovirus infection in L cells. Cell 28:605-612.
2. Beattie, E., K. Denzler, J. Tartaglia, M. Perkus, E. Paoletti, and B. L. Jacobs. 1995. Reversal of the interferon-sensitive phenotype of a vaccinia virus lacking E3L by expression of the reovirus S4 gene. J. Virol. 69:499-505.
3. Bernard, H.-U., G. Krammer, and W. G. Rowekamp. 1985. Construction of a fusion gene that confers resistance against hygromycin B to mammalian cells in culture. Exp. Cell Res. 158:237-243.
4. Bycroft, M., S. Grunert, A. G. Murzin, M. Proctor, and D. St. Johnston. 1995. NMR solution structure of a dsRNA binding domain from Drosophila staufen protein reveals homology to the N-terminal domain of ribosomal protein S5. EMBO J. 14:3563-3571.
5. Chang, H.-W., L. H. Uribe, and B. L. Jacobs. 1995. Rescue of vaccinia virus lacking the E3L gene by mutants of E3L. J. Virol. 69:6605-6608.
6. Chen, H. J., J. Remmler, J. C. Delaney, D. Messner, and P. Lobel. 1993. Mutational analysis of the cation-independent mannose 6-phosphate/insulin-like growth factor II receptor. J. Biol. Chem. 268:22338-22346.
7. Denzler, K. L., and B. L. Jacobs. 1994. Site-directed mutagenic analysis of reovirus σ3 protein binding to dsRNA. Virology 204:190-199.
8. Gerace, L. 1995. Nuclear export signals and the fast track to the cytoplasm. Cell 82:341-344.
9. Giantini, M., and A. J. Shatkin. 1989. Stimulation of chloramphenical acetyl-transferase mRNA translation by reovirus capsid polypeptide σ3 in cotransfectcd COS cells. J. Virol. 63:2415-2421.
10. Gossen, M., and H. Bujard. 1992. Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc. Natl. Acad. Sci. USA 89:5547-5551.
11. Huismans, H., and W. K. Joklik. 1976. Reovirus-coded polypeptides in infected cells: isolation of two native monomeric polypeptides with affinity for single-stranded and double-stranded RNA, respectively. Virology 70:411-424.
12. Imani, F., and B. L. Jacobs. 1988. Inhibitory activity for the interferon-induced protein kinase is associated with the reovirus serotype 1 σ3 protein. Proc. Natl. Acad. Sci. USA 85:7887-7891.
13. Joklik, W. K. 1983. The Reoviridae. Plenum Press, New York.
14. Kharrat, A., M. J. Macias, T. J. Gibson, M. Nilges, and A. Pastore. 1995. Structure of the dsRNA binding domain of E. coli RNase III. EMBO J. 14:3572-3584.
15. Lloyd, R., and A. J. Shatkin. 1992. Translation stimulation by reovirus polypeptide σ3: substitution for VAI RNA and inhibition of phosphorylation of the α subunit of eukaryotic initiation factor 2. J. Virol. 66:6878-6884.
16. Lloyd-Italia, R. 1992. Molecular mechanism of translational control mediated by the reovirus S4 gene. Ph.D. thesis. Rutgers University, New Brunswick, N.J.
17. Mabrouk, T., and G. Lemay. 1994. Mutations in a CCHC zinc-binding motif of the reovirus σ3 protein decrease its intracellular stability. J. Virol. 68:5287-5290.
18. Malim, M. H., S. Bohnlein, J. Hauber, and B. R. Cullen. 1989. Functional dissection of the HIV-1 Rev trans-activator - derivation of a trans-dominant repressor of Rev function. Cell 58:205-214.
19. 18a.Mathews, M. Personal communication.
20. Mathews, M. B., and T. Shenk. 1991. Adenovirus virus-associated RNA and translational control. J. Virol. 65:5657-5662.
21. McCormack, S. J., D. C. Thomis, and C. Samuel. 1992. Mechanism of interferon action: identification of a RNA binding domain within the N-terminal region of the RNA-dcpcndent P1/eIF-2α protein kinase. Virology 188:47-56.
22. Miller, J. E., and C. E. Samuel. 1992. Proteolytic cleavage of the reovirus sigma 3 protein results in enhanced double-stranded RNA-binding activity: identification of a repeated basic amino acid motif within the C-terminal binding region. J. Virol. 66:5347-5356.
23. Moss, B. 1990. Poxviridae and their replication. Raven Press, New York.
24. Pan, L., P. C. Beverley, and P. G. Isaacson. 1991. Lactate dehydrogenase (LDH) isoenzymes and proliferative activity of lymphoid cells - an immunocytochemical study. Clin. Exp. Immunol. 86:240-245.
25. Park, H., M. V. Davies, J. O. Langland, H.-W. Chang, Y. S. Nam, J. Tartaglia, E. Paoletti, B. L. Jacobs, R. J. Kaufman, and S. Venkatesan. 1994. TAR RNA-binding protein is an inhibitor of the interferon-induced protein kinase PKR. Proc. Natl. Acad. Sci. USA 91:4713-4717.
26. Schiff, L. A., M. L. Nibert, M. S. Co, E. Brown, and B. N. Fields. 1988. Distinct binding sites for zinc and double-stranded RNA in the reovirus outer capsid protein σ3. Mol. Cell. Biol. 8:273-283.
27. Seliger, L. S., M. Giantini, and A. J. Shatkin. 1992. Translational effect and sequence comparison of the three serotypes of the reovirus S4 gene. Virology 187:202-210.
28. Sharpe, A. H., L. B. Chen, and B. N. Fields. 1982. The interaction of mammalian reoviruses with the cytoskeleton of monkey kidney CV-1 cells. Virology 120:399-411.
29. Sharpe, A. H., and B. N. Fields. 1982. Reovirus inhibition of cellular RNA and protein synthesis: role of the S4 gene. Virology 122:381-391.
30. Smith, R. E., H. J. Zweerink, and W. K. Joklik. 1969. Polypeptide components of virions, top component and cores of reovirus type 3. Virology 39:791-798.
31. St. Johnston, D., N. H. Brown, J. G. Gall, and M. Jantsch. 1992. A conserved double-stranded RNA-binding domain. Proc. Natl. Acad. Sci. USA 89:10979-10983.
32. Tillotson, L., and A. J. Shatkin. 1992. Reovirus polypeptide σ3 and N-terminal myristoylation of polypeptide μ1 are required for site-specific cleavage to μ1C in transfected cells. J. Virol. 66:2180-2186.
33. Virgin, H. W., IV, M. A. Mann, B. N. Fields, and K. L. Tyler. 1991. Monoclonal antibodies to reovirus reveal structure/function relationships between capsid proteins and genetics of susceptibility to antibody action. J. Virol. 65:6772-6781.
34. Yuwen, H., J. H. Cox, J. W. Yewdell, J. R. Bennink, and B. Moss. 1993. Nuclear localization of a double-stranded RNA-binding protein encoded by the vaccinia virus E3L gene. Virology 195:732-744.