Association between toluene diisocyanate-induced asthma and DQB1 markers: A possible role for aspartic acid at position 57

European Respiratory Journal

Volumn 9, Issue 2, 1996, Pages 207-210

  Balboni, A ^a   Baricordi, O P ^a   Fabbri, L M ^a   Gandini, E ^a   Ciaccia, A ^a   Mapp, C E ^b,c  

^a UNIVERSITY OF FERRARA   (Italy)

^b UNIVERSITY OF PADOVA   (Italy)

^c Istituto di Medicina Clinica Padova   (Italy)

Author keywords

Asthma; Human leucocyte antigen; Isocyanates

Indexed keywords

ASPARTIC ACID; HLA DQ ANTIGEN; TOLUENE DIISOCYANATE;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DNA SEQUENCE; FEMALE; GENETIC PREDISPOSITION; GENETIC SUSCEPTIBILITY; HUMAN; MALE; MOLECULAR GENETICS; OCCUPATIONAL ASTHMA; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

ADULT; ALLELES; ASPARTIC ACID; ASTHMA; FEMALE; GENE FREQUENCY; GENETIC MARKERS; HAPLOTYPES; HLA-DQ ANTIGENS; HUMANS; MALE; MIDDLE AGED; OCCUPATIONAL DISEASES; OCCUPATIONAL EXPOSURE; POLYMERASE CHAIN REACTION; TOLUENE 2,4-DIISOCYANATE;

EID: 0030047399     PISSN: 09031936     EISSN: None     Source Type: Journal    
DOI: 10.1183/09031936.96.09020207     Document Type: Article

References (23)

1. Chan-Yeung M, Malo JL, Aetiological agents in occupational asthma. Eur Respir J 1994; 7: 346-371.
2. Butcher BT, Jones RN, O'Neil CE, et al. Longitudinal study of workers employed in the manufacture of toluene diisocyanate. Am Rev Respir Dis 1977; 116: 411-421.
3. Peters JM, Wegraan DH. Epidemiology and toluene diisocyanate (TDI) induced respiratory disease. Environ Health Perspect 1975; 11: 97-100.
4. Mapp CE, Saetta M, Maestrelli P, et al. Mechanisms and pathology of occupational asthma. Eur Respir J 1994; 7: 544-554.
5. Azzawi M, Bradley B, Jeffery PK, et al. Identification of activated T-lymphocytes and eosinophils in bronchial biopsies in stable atopic asthma. Am Rev Respir Dis 1990; 142: 1407-1413.
6. Bentley AM, Maestrelli P, Saetta M, et al. Activated T-lymphocytes and eosinophils in the bronchial mucosa in isocyanate-induced asthma. J Allergy Clin Immunol 1992; 89: 821-829.
7. Finotto S, Fabbri LM, Rado V, Mapp CE, Maestrelli P. Increase in numbers of CD8 positive lymphocytes and eosinophils in peripheral blood of subjects with late asthmatic reactions induced by toluene diisocyanate. Br J Ind Med 1991; 48: 116-121.
8. Bignon JS, Aron Y, Ju LY, et al. HLA class II alleles in isocyanate-induced asthma. Am J Respir Crit Care Med 1994; 149: 71-75.
9. Marsh DG, Hsu SH, Roebber M, et al. HLD-Dw2: a genetic marker for human immune response to short ragweed pollen allergen Ra5. J Exp Med 1982; 155: 1439-1451.
10. Marsh DG. Immunogenetic and immunochemical factors determining immune responsiveness to allergens: studies in unrelated subjects. In: Marsh DG, Blumenthal MN, eds. Genetic and Environmental Factors in Clinical Allergy. Minneapolis, University of Minnesota Press, 1990; pp. 97-123.
11. Maniatis A, Fritsch EF, Sambrock J. Molecular cloning, a laboratory manual. Cold Spring Harbor Laboratory, New York, 1989.
12. Nevinny-Stickel C, Keller E, Bettinotti MDL. Nonradioactive HLA class II typing using polymerase chain reaction, digoxigeninlabelled oligonucleotides, and chemiluminescent detection. In: Tsuji K, Aizawa M, Sasazuki T, eds. HLA 1991: Proceedings of the 11 th International Histocompatibility Workshop and Conference. Oxford Science publ., 1992; Vol. 2, p.302.
13. Wood WI, Gitscher J, Lasky LA, Lawn RM. Base composition-independent hybridization in tetramethylammonium chloride: a method for oligonucleotide screening of highly complex gene libraries. Proc Natl Acad Sci 1985; 82: 1585.
14. Haldane JBS. The estimation and significance of the logarithm of a ratio of frequencies. Am Hum Genet 1956; 20: 309-311.
15. Svejgaard A, Ryder LP. HLA and disease associations: detecting the strongest association. Tissue Antigens 1994; 43: 18-27.
16. Marsh SGE, Bodmer JG. HLA class II nucleotide sequences. Tissue Antigens 1992; 40: 229-243.
17. Maestrelli P, Di Stefano A, Occari P, et al. Cytokines in the airway mucosa of subjects with asthma induced by toluene diisocyanate. Am J Respir Crit Care Med 1995; 151: 607-612.
18. Evidence for an increase in atopic disease and possible causes. Special article. Clin Exp Allergy 1993; 23: 484-492.
19. Mapp CE, Boschetto P, Dal Vecchio L, Maestrelli P, Fabbri LM. Occupational asthma due to isocyanates. Eur Respir J 1988; 1: 273-279.
20. Kennedy AL, Stock MF, Alarie Y, Brown WE. Uptake and distribution of 14C during and following inhalation exposure to radioactive toluene diisocyanate. Toxicol Appl Pharmacol 1989; 100: 280-292.
21. Fukunaga M, Hirayama K, Sasazuki T. Activation of human CD8+ suppressor T-cells by antigen-specific CD4+ T-cell line in vitro. Hum Immunol 1989; 25: 157-168.
22. Maestrelli P, Del Prete GF, De Carli M, et al. CD8 T-cell clones producing interleukin-5 and interferon-gamma in bronchial mucosa of patients with asthma induced by toluene diisocyanate. Scand J Work Environ Health 1994; 20: 376-381.
23. Commissions des Communautes Europennes (CECA). Tables de reference pour les examens spirometriques. Office des publications officielles des Communautes Europennes. Luxembourg, 1971.