Cloning and characterization of the genomic region encoding toxin IV-5 from the scorpion Tityus serrulatus Lutz and Mello

Toxicon

Volumn 34, Issue 2, 1996, Pages 251-256

  Corona, Miguel ^a   Zurita, Mario ^a   Possani, Lourival D ^a   Becerril, Baltazar ^a  

^a INSTITUTO DE BIOTECNOLOGÍA   (Mexico)

Author keywords

[No Author keywords available]

Indexed keywords

OLIGONUCLEOTIDE; SCORPION VENOM;

ARTICLE; CLONING; GENE AMPLIFICATION; GENOME; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; TOXIN ANALYSIS;

SCORPIONES; TITYUS SERRULATUS;

EID: 0030046887     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/0041-0101(95)00129-8     Document Type: Article

References (25)

1. Arantes, E. C., Sampaio, S. V., Vieira, C. A. and Giglio, J. R. (1992) What is Tityustoxin? Toxicon 30, 786-789.
2. + channel. J. biol. Chem. 257, 2553-2558.
3. + channel-blocking toxins of the scorpion Centruroides noxius Hoffmann. Gene 128, 165-171.
4. Becerril, B., Corona, M., Mejia, M. C., Martin, B. M., Lucas, S., Bolivar, F. and Possani, L. D. (1993b) The genomic region encoding toxin gamma from the scorpion Tityus serrulatus contains an intron. FEBS Lett. 335, 6-8.
5. Bechis, G., Sampieri, F., Yuan P. M., Brando, T., Martin, M. F., Diniz, C. R. and Rochat, H. (1984) Amino acid sequence of toxin VII, a β-toxin from the venom of the scorpion Tityus serrulatus. Biochem. biophys. Res. Commun. 122, 1146-1153.
6. Binger, L. C. and Willis, J. H. (1994) Identification of the cDNA, gene and promoter for a major protein from flexible cuticles of the giant silkmoth Hyalophora cecropia. Insect Biochem. mol. Biol. 24, 989-1000.
7. Blaustein, M. P., Rogowski, R. S., Schneider, M. J. and Krueger, B. K. (1991) Polypeptide toxins from the venoms of Old World and New World scorpions preferentially block different potassium channels. Mol. Pharmacol. 40, 932-942.
8. + channel gating by an a scorpion toxin from Tityus serrulatus. J. gen. Physiol. 93, 67-83.
9. + channel. In: 5th Pan American Symposium of the International Society on Toxinology, Frederick, Maryland, U.S.A., August, 1995. Abstract p. 201.
10. Malehorn, D. E., Scott, K. J. and Shah, D. M. (1993) Structure and expression of a barley acidic beta-glucanase gene. Plant mol. Biol. 22, 347-360.
11. Mansuelle, P., Martin-Eauclaire, M. F., Chavez-Olortegui, C., de Lima, M. E., Rochat, H. and Granier, C. (1992) The beta-type toxin TsII from the scorpion Tityus serrulatus: amino acid sequence determination and assessment of biological and antigenic properties. Natural Toxins 1, 119-125.
12. Marangoni, S., Ghiso, J., Sampaio, S. V., Arantes, E. C., Giglio, J. R., Olveira, B. and Frangione, B. (1990) The complete amino acid sequence of toxin TsTX-VI from the venom of the scorpion Tityus serrulatus. J. Prot. Chem. 9, 595-601.
13. Martin-Eauclaire, M. F., Delabre, M. L., Ceard, B., Ribeiro, A., Sogaard, M., Svensson, B., Diniz, C. R., Smith, L. A., Rochat, H. and Bougis, P. E. (1992a) In: Recent Advances in Toxinology Research, Vol. 1, pp. 196-209 (Gopalakrishnakone, P. and Tan C. K. Eds). Singapore: Singapore University Press.
14. Martin-Eauclaire, M. F., Ceard, B., Ribeiro, A. M., Diniz, C. R., Rochat, H. and Bougis, P. E. (1992b) Molecular cloning and nucleotide sequence analysis of a cDNA encoding the main β-neurotoxin from the venom of the South American scorpion Tityus serrulatus. FEBS Lett. 302, 220-222.
15. Martin-Eauclaire, M. F., Ceard, B., Ribeiro, A. M., Diniz, C. R., Rochat, H. and Bougis, P. E. (1994) Biochemical, pharmacological and genomic characterisation of Ts IV, an α-toxin from the venom of the South American scorpion Tityus serrulatus. FEBS Lett. 342, 181-184.
16. Meyer, F., Schmidt, H. J. and Heckmann, K. (1992) Pheromone 4 gene of Euplotes octocarinatus. Dev. Genet. 13, 16-25.
17. Possani, L. D., Martin, B. M., Mochca-Morales, J. and Svendsen, I. (1981) Purification and chemical characterization of the major toxins from the venom of the Brazilian scorpion Tityus serrulatus Lutz and Mello. Carlsberg Res. Commun. 46, 195-205.
18. Possani, L. D., Martin, B. M. and Svendsen, I. (1982) The primary structure of Noxiustoxin: A K channel blocking peptide, purified from the venom of the scorpion Centruroides noxius Hoffmann. Carlsberg Res. Commun. 47, 285-289.
19. Possani, L. D., Martin, B. M., Svendsen, I., Rode, G. S. and Erickson, B. W. (1985) Scorpion toxins from Centruroides noxius and Tityus serrulatus. Primary structures and sequence comparison by metric analysis. Biochem. J. 229, 739-750.
20. Possani, L. D., Martin, B. M., Fletcher, M. D. and Fletcher, P. L. Jr. (1991) Discharge effect on pancreatic exocrine secretion produced by toxins purified from Tityus serrulatus scorpion venom. J. biol. Chem. 266, 3178-3185.
21. Possani, L. D., Fletcher, P. L., Fletcher, M. D., Rode, G. S., Mochca-Morales, J., Lucas, S., Coronas, F. V., Alagon, A. C. and Martin, B. M. (1992) Structural and functional characteristics of toxins purified from the Brazilian scorpion Tityus serrulatus Lutz and Mello. Mem. Inst. Butantan 54, 35-52.
22. 2IV from Tityus serrulatus scorpion venom. Toxicon 29, 663-672.
23. Wang, J., Xu, P. and Fincher, G. B. (1992) Purification, characterization and gene structure of (1 → 3)-beta-glucanase isoenzyme GIII from barley (Hordeum vulgare). Eur. J. Biochem. 209, 103-109.
24. Xu, P., Wang, J. and Fincher, G. B. (1992) Evolution and differential expression of the (1 → 3)-beta-glucan endohydrolase-encoding gene family in barley, Hordeum vulgare. Gene 120, 157-165.
25. Yatani, A., Kirsch, G. E., Possani, L. D. and Brown, A. M. (1988) Effects of New World scorpion toxins on single-channel and whole cell cardiac sodium currents. Am. J. Physiol. 254, H443-H451.