Tyrosine phosphorylation of extracellular signal-regulated protein kinase 4 in response to growth factors

Journal of Neurochemistry

Volumn 66, Issue 3, 1996, Pages 1191-1197

  Peng, Xing ^a   Angelastro, James M ^a   Greene, Lloyd A ^a  

^a New York Presbyterian Columbia University Medical Center   (United States)

Author keywords

Extracellular signal regulated protein kinase 4; Growth factors; Mitogen activated protein kinases; PC12 cells; Tyrosine phosphorylation

Indexed keywords

CYCLIC AMP DERIVATIVE; EPIDERMAL GROWTH FACTOR; GROWTH FACTOR; INSULIN; MITOGEN ACTIVATED PROTEIN KINASE; NERVE GROWTH FACTOR;

ANIMAL CELL; ARTICLE; CELL GROWTH; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; NONHUMAN; PHEOCHROMOCYTOMA CELL; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 0030046667     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1996.66031191.x     Document Type: Article

References (30)

1. Alvarez E., Northwood I. C., Gonzalez F. A., Latour D. A., Seth A., Abate C., Curran T., and Davis R. J. (1991) Pro-Leu-Ser/ Thr-Pro is a consensus primary sequence for substrate protein phosphorylation. Characterization of the phosphorylation of c-myc and c-jun proteins by an epidermal growth factor receptor threonine 669 protein kinase J. Biol. Chem. 266, 15277-15285.
2. Blenis J. (1993) Signal transduction via the MAP kinases: proceed at your own RSK. Proc. Natl. Acad. Sci. USA 90, 5889-5892.
3. Boulton T. G and Cobb M. H. (1991) Identification of multiple extracellular signal-regulated kinases (ERKs) with antipeptide antibodies. Cell Regul. 2, 357-371.
4. Boulton T. G., Yancopoulos G. D., Gregory J. S., Slaughter C., Moomaw C., Hsu J., and Cobb M. H. (1990) An insulin-stimulated protein kinase similar to yeast kinases involved in cell cycle control. Science 249, 64-67.
5. Boulton T. G., Nye S. H., Robbins D. J., Ip N. Y., Radziejewska E., Morgenbesser S. D., DePinho R. A., Panayotatos N., Cobb M. H., and Yancopoulos G. D. (1991a) ERKs: a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF. Cell 65, 663-675.
6. Boultou T. G., Gregory J. S., and Cobb M. H. (1991b) Purification and properties of extracellular signal-regulated kinase 1, an insulin-stimulated microtubule-associated protein 2 kinase. Biochemistry 30, 278-286.
7. Chen R. H., Sarnecki C., and Blenis J. (1992) Nuclear localization and regulation of ERK- and rsk-encoded protein kinases. Mol. Cell. Biol. 12, 915-927.
8. Chuang C. F. and Ng S. Y. (1994) Functional divergence of the MAP kinase pathway. ERK1 and ERK2 activate specific transcription factors. FEBS Lett 346, 229-234.
9. Cobb M. H., Boulton T. G., and Robbins D. J. (1991) Extracellular signal-regulated kinases: ERKs in progress. Cell Regul. 2, 965-978.
10. Frödin M., Peraldi P., and Van Obberghen E. (1994) Cyclic AMP activates the mitogen-activated protein kinase cascade in PC12 cells. J. Biol. Chem. 269, 6207-6214.
11. Gonzalez F. A., Seth A., Raden D. L., Bowman D. S., Fay F. S., and Davis R. J. (1993) Serum-induced translocation of mitogen-activated protein kinase to the cell surface ruffling membrane and the nucleus. J. Cell Biol. 122, 1089-1101.
12. Greene L. A., Sobeih M. M., and Teng K. K. (1991) Methodologies for the culture and experimental use of the PC12 rat pheochromocytoma cell line, in Culturing Nerve Cells (Banker G. and Goslin K., eds), pp. 207-226. MIT Press, Cambridge, Massachusetts.
13. Heasley L. E. and Johnson G. L. (1992) The beta-PDGF receptor induces neuronal differentiation of PC12 cells. Mol. Biol. Cell. 3, 545-553.
14. Hibi M., Lin A., Smeal T., Minden A., and Karin M. (1993) Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain. Genes Dev. 7, 2135-2148.
15. Kyriakis J. M., Banerjee P., Nikolakaki E., Dai T. Rubie E. A., Ahmad M. F., Avruch J., and Woodgett J. R. (1994) The stress-activated protein kinase subfamily of c-Jun kinases. Nature 369, 156-160.
16. Loeb D. M. and Greene L. A. (1993) Transfection with trk restores "slow" NGF binding, efficient NGF uptake, and multiple NGF responses to NGF-nonresponsive PC12 cell mutants. J. Neurosci. 13, 2919-2929.
17. Marshall C. J. (1994) MAP kinase kinase kinase, MAP kinase kinase and MAP kinase. Curr. Opin. Genet. Dev. 4, 82-89.
18. Mobley W. C., Schenker A., and Shooter E. M. (1976) Characterization and isolation of proteolytically modified nerve growth factor. Biochemistry 15, 5543-5552.
19. Nishida E. and Gotoh Y. (1993) The MAP kinase cascade is essential for diverse signal transduction pathways. Trends Biochem Sci. 18, 128-131.
20. O'Farrell P. H. (1975) High resolution two-dimensional electrophoresis of proteins. J. Biol. Chem. 250, 4007-4021.
21. Pulverer B. J., Kyriakis J. M., Avruch J., Nikolakaki E., and Woodgett J. R. (1991) Phosphorylation of c-jun mediated by MAP kinases. Nature 353, 670-674.
22. Qiu M. S. and Green S. H. (1992) PC12 cell neuronal differentiation is associated with prolonged p21ras activity and consequent prolonged ERK activity. Neuron 9, 705-717.
23. Rabin S. J., Cleghon V., and Kaplan D. R. (1993) SNT, a differentiation-specific target of neurotrophic factor-induced tyrosine kinase activity in neurons and PC12 cells. Mol. Cell. Biol. 13, 2203-2213.
24. Robbins D. J., Cheng M., Zhen E., Vanderbilt C. A., Feig L. A., and Cobb M. H. (1992) Evidence for a Ras-dependent extracellular signal-regulated protein kinase (ERK) cascade. Proc. Natl. Acad. Sci. USA 89, 6924-6928.
25. Sanghera J. S., Peter M., Nigg E. A., and Pelech S. L. (1992) Immunological characterization of avian MAP kinases: evidence for nuclear localization. Mol. Biol. Cell 3, 775-787.
26. Schlessinger J. (1993) How receptor tyrosine kinases activate Ras. Trends Biochem. Sci. 18, 273-275.
27. Stephens R. M., Loeb D. M., Copelan T. D., Pawaon T., Greene L. A., and Kaplan D. R. (1994) Trk receptors use redundant signal transduction pathways involving SHC and PLC-γ1 to mediate NGF responses. Neuron 12, 1-20.
28. Thomas S. M., DeMarco M., D'Arcangelo G., Halegoua S., and Brugge J. S. (1992) Ras is essential for nerve growth factor-and phorbol ester-induced tyrosine phosphorylation of MAP kinases. Cell 68, 1031-1040.
29. Traverse S., Gomez N., Paterson H., Marshall C. J., and Cohen P. (1992) Sustained activation of the mitogen-activated protein (MAP) kinase cascade may be required for differentiation of PC12 cells: comparison of the effects of nerve growth factor and epidermal growth factor. Biochem. J. 288, 351-355.
30. Wood K. W., Sarnecki C., Roberts T. M., and Blenis J. (1992) Ras mediates nerve growth factor receptor modulation of three signal-transducing protein kinases: MAP kinase, Raf-1, and RSK. Cell 68, 1041-1050.