Serum free testosterone in polycystic ovary syndrome measured with a new reference method

Fertility and Sterility

Volumn 65, Issue 1, 1996, Pages 55-60

  Penttila, T A ^a   Anttila, L ^a   Torma, A ^a   Koskinen, P ^a   Erkkola, R ^a   Irjala, K ^a  

^a TURKU UNIVERSITY HOSPITAL   (Finland)

Author keywords

free testosterone; Polycystic ovary syndrome; T:SHBG ratio; testosterone

Indexed keywords

ANDROSTENEDIONE; FOLLITROPIN; INSULIN; LUTEINIZING HORMONE; SEX HORMONE BINDING GLOBULIN; TESTOSTERONE;

ADOLESCENT; ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HORMONE BLOOD LEVEL; HUMAN; OVARY POLYCYSTIC DISEASE; PRIORITY JOURNAL; RADIOIMMUNOASSAY; TRANSVAGINAL ECHOGRAPHY;

EID: 0030046592     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0015-0282(16)58027-3     Document Type: Article

References (25)

1. I.F. Stein M.L. Leventhal Amenorrhea associated with bilateral polycystic ovaries Am J Obstet Gynecol 29 1935 181 191
2. D.W. Saxton C.M. Farquhar T. Rae R.W. Beard M.C. Anderson J. Wadsworth Accuracy of ultrasound measurement of female pelvic organs Br J Obstet Gynaecol 97 1990 695 699
3. S. Robinson D.A. Rodin A. Deacon M.J. Wheeler R.N. Clayton Which hormone tests for the diagnosis of polycystic ovary syndrome? Br J Obstet Gynaecol 99 1992 232 238
4. L. Anttila Y.-Q. Ding K. Ruutiainen R. Erkkola K. Irjala I. Huhtaniemi Clinical features and circulating gonadotropin, insulin and androgen interactions in women with polycystic ovarian disease Fertil Steril 55 1991 1057 1061
5. T.D. Pache F.H. de Jong W.C. Hop B.C.J.M. Fauser Association between ovarian changes assessed by transvaginal sonography and clinical and endocrine signs of the polycystic ovary syndrome Fertil Steril 59 1993 544 549
6. S. Franks Polycystic ovary syndrome: a changing perspective Clin Endocrinol (Oxf) 31 1989 87 120
7. R.S. Mathur L.O. Moody S. Landgrebe H.O. Williamson Plasma androgens and sex hormone-binding globulin in the evaluation of hirsute females Fertil Steril 35 1981 29 35
8. L.F. Blight S.J. Judd G.H. White Relative diagnostic value of serum non-SHBG-bound testosterone, free androgen index and free testosterone in the assessment of mild to moderate hirsutism Ann Clin Biochem 26 1989 311 316
9. T.J. Wilke D.J. Utley Total testosterone, free-androgen index, calculated free testosterone, and free testosterone by analog RIA compared in hirsute women and in otherwise-normal women with altered binding of sex-hormone-binding globulin Clin Chem 33 1987 1372 1375
10. K. Yoshino K. Takahashi Y. Eda S. Okada M. Kitao Plasma androgens and sex hormone binding globulin in women with polycystic ovaries diagnosed by transvaginal ultrasound J Reprod Med 38 1993 858 862
11. J.A. Eden J. Place G.D. Carter J. Jones J. Alaghband-Zadeh M. Pawson Elevated free androgen index as an indicator of polycystic ovaries in oligomenorrhea without obesity or hirsuties Ann Clin Biochem 25 1988 346 349
12. A. Törmä T.-A. Jaatinen H.-L. Kaihola P. Koskinen K. Irjala A method for free testosterone in premenopausal women involving equilibrium dialysis, chromatography, and radioimmunoassay Steroids. 60 1995 285 289
13. S. Grenman K. Rönnemaa K. Irjala H.-L. Kaihola M. Grönroos Sex steroid, gonadotropin, Cortisol, and prolactin levels in healthy, massively obese women: correlation with abdominal fat cell size and effect of weight reduction J Clin Endocrinol Metab 63 1986 1257 1261
14. J. Adams D.W. Polson N.A. Abdulwahid D.V. Morris S. Franks D.H. Mason Multifollicular ovaries: clinical and endocrine features and response to pulsatile gonadotrophin releasing hormone Lancet 2 1985 1375 1379
15. D. Ferriman J.D. Gallwey Clinical assessment of body hair growth in women J Clin Endocrinol Metab 21 1961 1440 1445
16. L. Anttila P. Koskinen H.-L. Kaihola R. Erkkola K. Irjala K. Ruutiainen Serum androgen and gonadotropin levels decline after progestogen-induced withdrawal bleeding in oligo-menorrheic women with or without polycystic ovaries Fertil Steril 58 1992 697 702
17. L. Anttila P. Koskinen K. Irjala H.-L. Kaihola Reference intervals for serum sex steroids and gonadotropins in regularly menstruating women Acta Obstet Gynecol Scand 70 1991 475 481
18. M.H. Zweig G. Campbell Receiver-operating characteristic (ROC) plots: a fundamental evaluation tool in clinical medicine Clin Chem 39 1993 561 577
19. J.B. Smith W. Jubiz A source of error in equilibrium dialysis Steroids 36 1980 393 403
20. P.S. Sharp D.S. Kiddy M.J. Reed V. Anyaoku D.G. Johnston S. Franks Correlation of plasma insulin and insulin-like growth factor-I with indices of androgen transport and metabolism in women with polycystic ovary syndrome Clin Endocrinol (Oxf) 35 1991 253 257
21. D.S. Kiddy P.S. Sharp D.M. White M.F. Scanion H.D. Mason C.S. Bray Differences in clinical and endocrine features between obese and non-obese subjects with polycystic ovary syndrome: An analysis of 263 consecutive cases Clin Endocrinol (Oxf) 32 1990 213 220
22. T.-A. Jaatinen L. Anttila R. Erkkola P. Koskinen P. Laippala K. Ruutiainen Hormonal responses to physical exercise in patients with polycystic ovarian syndrome Fertil Steril 60 1993 262 267
23. J. Holte T. Bergh G. Gennarelli L. Wide The independent effects of polycystic ovarian syndrome and obesity on serum concentrations of gonadotropins and sex steroids in premenopausal women Clin Endocrinol (Oxf) 41 1994 473 481
24. J. Slowinska-Srzednicka W. Zgliczynski A. Makowska W. Jeske A. Brezinska P. Soszynski An abnormality of the growth hormone/insulin-like growth factor-I axis in women with polycystic ovary syndrome due to coexistent obesity J Clin Endocrinol Metab 74 1992 1432 1435
25. T.-A. Jaatinen I. Matinlauri L. Anttila P. Koskinen R. Erkkola K. Irjala Serum total renin is elevated in women with polycystic ovarian syndrome Fertil Steril 63 1995 1000 1004