Hemodynamic Responses to Intravascular Injection of Epinephrine-containing Epidural Test Doses in Adults during General Anesthesia

Anesthesiology

Volumn 84, Issue 1, 1996, Pages 81-87

  Liu, Spencer S ^a   Carpenter, Randall L ^b  

^a VIRGINIA MASON MEDICAL CENTER   (United States)

^b WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

Anesthesia: epidural; general; Anesthetics, volatile: isoflurane; Hemodynamics: blood pressure; heart rate; Sympathetic nervous system, catecholamines: epinephrine

Indexed keywords

ADRENALIN; ISOFLURANE; LIDOCAINE; NITROUS OXIDE;

ADRENERGIC SYSTEM; ADULT; ANESTHESIA LEVEL; ARTICLE; BLOOD PRESSURE MEASUREMENT; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; EPIDURAL ANESTHESIA; FEMALE; GENERAL ANESTHESIA; HEART RATE; HEMODYNAMICS; HUMAN; MALE; MEAN ARTERIAL PRESSURE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL;

ADULT; ANESTHESIA, EPIDURAL; ANESTHESIA, GENERAL; ANESTHETICS, INHALATION; BODY TEMPERATURE; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; EPINEPHRINE; FEMALE; HEMODYNAMIC PROCESSES; HUMANS; INJECTIONS, EPIDURAL; INJECTIONS, INTRAVENOUS; ISOFLURANE; MALE; NITROUS OXIDE;

EID: 0030046379     PISSN: 00033022     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000542-199601000-00010     Document Type: Article

References (32)

1. Shir Y, Raja SN, Frank SM: The effect of epidural versus general anesthesia on postoperative pain and analgesic requirements in patients undergoing radical prostatectomy. ANESTHESIOLOGY 1994; 80: 49-56
2. Dahl JB, Hansen BL, Hjortso NC, Erichsen CJ, Moiniche S, Kehlet H: Influence of timing on the effect of continuous extradural analgesia with bupivacaine and morphine after major abdominal surgery. Br J Anaesth 1992; 69:4-8
3. Guinard JP, Mulroy MF, Carpenter RL, Knopes KD: Test doses: Optimal epinephrine content with and without acute beta-adrenergic blockade. ANESTHESIOLOGY 1990; 73:386-92
4. Colonna RP, Lingaraju N, Godfrey SD, Braitman LE: Epidural test dose and intravascular injection in obstetrics: Sensitivity, specificity, and lowest effective dose. Anesth Analg 1992; 75:372-6
5. Prince G, McGregor D: Obstetric epidural test doses: A reappraisal. Anaesthesia 1986; 41:1240-50
6. Colonna RP, Lingaraju N, Braitman LE: Epidural test dose: Lidocaine 100 mg, not chloroprocaine, is a symptomatic marker of i.v. injection in labouring parturients. Can J Anaesth 1993; 40:714-7
7. Moore DC, Batra MS: The component of an effective test dose prior to epidural block. ANESTHESIOLOGY 1981; 55:693-6
8. Tanaka M, Yamamoto S, Ashimura H, Iwai M, Matsumiya N: Efficacy of an epidural test dose in adult patients anesthetized with isoflurane: Lidocaine containing 15 ug epinephrine reliably increases arterial blood pressure, but not heart rate. Anesth Analg 1995; 80: 310-4
9. Eger EI: Isoflurane: A review. ANESTHESIOLOGY 1981; 55:559-76
10. Zbinden AM, Maggiorini M, Petersen FS, Lauber R, Thomson DA, Minder CE: Anesthetic depth defined using multiple noxious stimuli during isoflurane/oxygen anesthesia: I. Motor reactions. ANESTHESIOLOGY 1994; 80:253-60
11. Hornbein TF, Eger EI, Winter PM, Smith G, Wetstone D, Smith KH: The minimum alveolar concentration of nitrous oxide in man. ANESTHESIOLOGY 1982; 61:553-6
12. Glantz SA: Primer of Biostatistics. 2nd edition. New York, Mcgraw-Hill, 1987, pp 186-9
13. McKinney MS, Fee JP, Clarke RS: Cardiovascular effects of isoflurane and halothane in young and elderly adult patients. Br J Anaesth 1993; 71:696-701
14. Divcic A, Muzi M, Ebert TJ: The effects of clonidine on desflurane-mediated sympathoexcitation in humans. Anesth Analg 1995; 80:773-9
15. Palmisano BW, Mehner RW, Stowe DF, Bosnjak ZJ, Kampine JP: Direct myocardial effects of halothane and isoflurane: Comparison between adult and infant rabbits. ANESTHESIOLOGY 1994; 81:718-29
16. Priebe H-J: Differential effects of isoflurane on regional right and left ventricular performances, and on coronary, systemic, and pulmonary hemodynamics in the dog. ANESTHESIOLOGY 1987; 66:262-72
17. Sellgren J, Ponten J, Wallin BG: Percutaneous recording of muscle nerve sympathetic activity during propofol, nitrous oxide, and isoflurane anesthesia in humans. ANESTHESIOLOGY 1990; 73:20-7
18. Kato M, Komatsu T, Kimura T, Sugiyama F, Nakashima K, Shimada Y: Spectral analysis of heart rate variability during isoflurane anesthesia. ANESTHESIOLOGY 1992; 77:669-74
19. Deegan R, Bing H, Wood AJJ, Wood M: Effect of enflurane and isoflurane on norepinephrine kinetics: A new approach to assessment of sympathetic function during anesthesia. Anesth Analg 1993; 77: 49-54
20. Pagel PS, Kampine JP, Schmeling WT, Warltier DC: Effects of nitrous oxide on myocardial contractility as evaluated by the preload recruitable stroke work relationship in chronically instrumented dogs. ANESTHESIOLOGY 1990; 73:1148-57
21. Lam AM, Mayberg TS, Eng CC, Cooper JO, Bachenberg KL, Mathisen TL: Nitrous oxide-isoflurane anesthesia causes more cerebral vasodilation than an equipotent dose of isoflurane in humans. Anesth Analg 1994; 78:462-8
22. Navarro R, Weiskopf RB, Moore MA, Lockhart S, Eger EI, Koblin D, Lu G, Wilson C: Humans anesthetized with sevoflurane or isoflurane have similar arrhythmic response to epinephrine. ANESTHESIOLOGY 1994; 80:545-9
23. Jordan D, Shulman SM, Miller EJ: Esmolol hydrochloride, sodium nitroprusside, and isoflurane differ in their ability to alter peripheral sympathetic responses. Anesth Analg 1993; 77:281-90
24. Galletly DC, Westenberg AM, Robinson BJ, Corfiatis T: Effect of halothane, isoflurane and fentanyl on spectral components of heart rate variability. Br J Anaesth 1994; 72:177-80
25. Ebert TJ: Differential effects of nitrous oxide on baroreflex control of heart rate and peripheral sympathetic nerve activity in humans. ANESTHESIOLOGY 1990; 72:16-22
26. Desparmet J, Mateo J, Ecoffey C, Mazoit X: Efficacy of an epidural test dose in children anesthetized with halothane. ANESTHESIOLOGY 1990; 72:249-51
27. Gieraerts R, Van ZA, De WA, Vaes L: Ten ml bupivacaine 0.125% with 12.5 micrograms epinephrine is a reliable epidural test dose to detect inadvertent intravascular injection in obstetric patients: A double-blind study. Acta Anaesthesiol Scand 1992; 36:656-9
28. Leighton BL, De SC, Norris MC, Chayen B: Isoproterenol is an effective marker of intravenous injection in laboring women. ANESTHESIOLOGY 1989; 71:206-9
29. Fleisher LA, Frank SM, Shir Y, Estafanous M, Kelly S, Raja SN: Cardiac sympathovagal balance and peripheral sympathetic vasoconstriction: Epidural versus general anesthesia. Anesth Analg 1994; 79: 165-71
30. Valley MA, Bourke DL, Hamill MP, Raja SN: Time course of sympathetic blockade during epidural anesthesia: Laser Doppler flowmetry studies of regional skin perfusion. Anesth Analg 1993; 76: 289-94
31. Stevens RA, Artuso JD, Kao TC, Bray JG, Spitzer L, Louwsma DL: Changes in human plasma catecholamine concentrations during epidural anesthesia depend on the level of block. ANESTHESIOLOGY 1991; 74:1029-34
32. Stevens RA, Beardsley D, White JL, Kao T-Z, Teague PJ, Spitzer L: Does the choice of local anesthetic affect the catecholamine response to stress during epidural anesthesia. ANESTHESIOLOGY 1993; 79:1219-26