Cicletanine inhibits endothelin-1-induced hypertrophy of rat cardiomyocytes

Pharmacometrics

Volumn 51, Issue 1, 1996, Pages 1-6

  Lin, Meihong ^b   Ito, Hiroshi ^b   Akimoto, Hajime ^b   Hata, Mimi ^b   Fujisaki, Hiroyuki ^b   Adachi, Susumu ^b   Marumo, Fumiaki ^b   Hiroe, Michiaki ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b NONE

Author keywords

Cardiomyocytes; Cicletanine; Cyclic guanosine monophosphate; Endothelin 1; Hypertrophy

Indexed keywords

ALPHA ACTIN; ATRIAL NATRIURETIC FACTOR; CICLETANINE; CYCLIC GMP; ENDOTHELIN 1; MESSENGER RNA;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; HEART MUSCLE CELL; HEART VENTRICLE HYPERTROPHY; NEWBORN; NONHUMAN; PROTEIN SYNTHESIS; RAT;

EID: 0030045983     PISSN: 03008533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (29)

1. Bouthier, J.A., Safar, M.E., Deschamps, E. and Tarrade, T. (1988): Haemodynamic effects of an antihypertensive diuretic substance on the forearm circulation of patients with essential hypertension, Drugs Exp. Clin. Res., 14, 221-224.
2. Castro, A., Florentino, A. and Fuentes, J.A. (1988): Antihypertensive effect of non-diuretic doses of cicletanine on a stress-induced model in the rat, Drugs Exp. Clin. Res., 14, 97-101.
3. Chabrier, P.E., Guinot, P., Tarrade, T., Auguet, M., Cabanie, M., Clostre, F., Etienne, A., Esanu, A. and Braquet, P. (1988): Cicletanine, Cardiovasc. Drug Rev., 6, 166-179.
4. Feinberg, A.P. and Vogelstein, B.A. (1983): Technique for radiolabeling DNA restriction endonuclease fragments to high specific activity, Anal. Biochem., 132, 6-13.
5. Fujisaki, H., Ito, H., Hirata, Y., Tanaka, M., Hata, M., Lin, M., Adachi, S., Akimoto. H., Marumo, F. and Hiroe, M. (1995): Natriuretic peptides inhibit angiotensin II-induced proliferation of rat cardiac fibroblasts by blocking endothelin-1 gene expression, J. Clin. Invest., 96, 1059-1065.
6. Hahn, A.W., Resink, T.J., Scott, B.T., Powell, J., Dohy, Y. and Buhler, F.R. (1990): Stimulation of endothelin mRNA and secretion in rat vascular smooth muscle cells: a novel autocrine function, Cell Regul., 1, 649-659.
7. Hirata, Y., Takagi, Y., Fukuda, Y. and Marumo, F. (1989): Endothelin is a potent mitogen for rat vascular smooth muscle cells, Atherosclerosis, 78, 225-228.
8. Ito, H., Miller, S.C., Billingham, M.E., Akimoto, H., Torti, S., Wade, R., Gahlmann, R., Lyons, G , Kedes, L. and Torti, F.M. (1990): Doxorubicin selectively inhibits muscle gene expression in cardiac muscle cells in vitro and in vivo, Proc. Natl. Acad. Sci. USA, 87, 4275-4279.
9. Ito, H., Hirata, Y., Hiroe, M., Tsujino, M., Adachi, S., Takamoto, T., Nitta, M., Taniguchi, K. and Marumo, F. (1991): Endothelin-1 induces hypertrophy with enhanced expression of muscle-specific genes in cultured neonatal rat cardiomyocytes, Circ. Res., 69, 209-215.
10. Ito, H., Pratt, R.E., Ohno, M. and Dzau, V.J. (1992): Atrial natriuretic polypeptide as a novel antigrowth factor of endothelial cells, Hypertension, 19, 758-761.
11. Ito, H., Hiroe, M., Hirata, Y., Tsujino, M., Adachi, S., Shichiri, M., Koike, A., Nogami, A. and Marumo, F. (1993a): Insulin-like growth factor-I induces hypertrophy with enhanced expression of muscle-specific genes in cultured rat cardiomyocytes, Circulation, 87, 1715-1721.
12. Ito, H., Hirata, Y., Adachi, S., Tanaka, M., Tsujino, M., Koike, A., Nogami, A., Marumo, F. and Hiroe, M. (1993b): Endothelin-1 is an autocrine/paracrine factor in the mechanism of angiotensin II-induced hypertrophy in cultured rat cardiomyocytes, J. Clin. Invest., 92, 398-403.
13. Izumo, S., Nadal-Ginard, B. and Mahadavi, V. (1988): Protooncogene induction and reprogramming of cardiac gene expression produced by pressure overload, Proc. Natl. Acad. Sci. USA, 85, 339-343.
14. Komuro, I., Katoh, Y., Kaida, T., Shibazaki, Y., Kurabayashi, M., Hoh, E., Takaku, F. and Yazaki, Y. (1991): Mechanical loading stimulates cell hypertrophy and specific gene expression in cultured rat cardiac myocytes, J. Biol. Chem., 266, 1265-1268.
15. Lang, D. and Lewis, M.J. (1991): Endothelium-derived relaxing factor inhibits the ET-1-induced increase in protein kinase C activity in rat aorta, Br. J. Pharmacol., 104, 139-144.
16. Ohta, K., Hirata, Y., Imai, T., Kanno, K., Emori, T., Shichiri, M. and Marumo, F. (1990): Cytokine-induced release of endothclin-1 from porcine renal epithelial cell line, Biochem. Biophys. Res. Commun., 169, 578-584.
17. Sakamoto, H., Sasaki, S., Hirata, Y., Imai, T., Ando, K., Ida, T., Sakurai, T., Yanagisawa, M., Masaki, T. and Marumo, F. (1990): Production of endothelin-1 by rat culture mesangial cells, Biochem. Biophys. Res. Commun., 169, 462-468.
18. Schiaffino, S., Samuel, J.L., Sassoon, S.D., Lompre, A.M., Garner, I., Marotte, F., Buckingham, M., Rappaport, L. and Schwartz, K. (1989): Nonsynchrous accumulation of skeletal α-actin and β-myosin heavy chain mRNAs during early stages of pressure-overload-induced cardiac hypertrophy demonstrated by in situ hybridization, Circ. Res., 64, 937-948.
19. Schwartz, K., de la Bastie, D, Bouveret, P., Oliviero, P., Alonso, S. and Buckingham, M. (1986): α-Skeletal muscle actin mRNA's accumulate in hypertrophied adult rat hearts, Circ. Res., 59, 551-555.
20. Shichiri, M., Hirata, Y., Nakajima, T., Ando, K., Imai, T., Yanagisawa, M., Masaki, T. and Marumo, F. (1991): Endothelin-1 is an autocrine/paracrine growth factor for human cancer cell lines, J. Clin. Invest., 87, 1867-1871.
21. Shubeita, H.E., McDonough, P.M., Harris, A.N., Knowlton, K.U., Glembotski, C.C., Brown, J.H. and Chien, K.R. (1990): Endothelin induction of inositol phospholipid hydrolysis, sarcomere assembly, and cardiac gene expression in ventricular myocytes: a paracrine mechanism for myocardial cell hypertrophy, J. Biol. Chem., 265, 20555-20562.
22. Shubeita, H.E., Martinson, E.A., Bilsen, M.V., Chien, K.R. and Brown, J.H. (1992): Transcriptional activation of the cardiac myosin light chain 2 and atrial natriuretic factor genes by protein kinase C in neonatal rat ventricular myocytes, Proc. Natl. Acad. Sci. USA, 89, 1305-1309.
23. ++-regulated protein kinases and relationship to vaso-relaxation by cicletanine, J. Pharmacol Exp. Ther., 257, 382-391.
24. Simpson, P. and Savion, S. (1982). Differentiation of rat myocytes in single cell cultures with and without proliferation nonmyocardial cells, Circ. Res., 50, 101-116.
25. Simpson, P.C. (1989): Molecular mechanisms in myocardial hypertrophy, Heart Failure, 5, 113-129.
26. Simpson, P.C., Kariya, K., Karns, L.R., Long, C.S. and Karliner, J.S. (1991): Adrenergic hormones and control of cardiac myocyte growth, Mol. Cell. Biochem., 104, 35-43.
27. Takuwa, N., Takuwa, Y., Yanagisawa, M., Yamashita, K. and Masaki, T. (1989): A novel vasoactive peptide endothelin stimulates mitogenesis through inositol lipid turnover in Swiss 3T3 fibroblasts, J. Biol. Chem., 264, 7856-7861.
28. Weiss, G.B., Winquist, P.J. and Silver, P.J. (1990): Vascular smooth muscle and vasodilators. In: Antonaccio, M, ed., Cardiovascular Pharmacology, 3rd ed. New York: Raven Press, 75-105.
29. Yanagisawa, M., Kurihara, H., Kimura, S., Tomobe, Y., Kobayashi, M., Mitsui, Y., Yazaki, Y., Goto, K. and Masaki, T. (1988): A novel potent vasoconstrictor peptide produced by vascular endothelial cell, Nature, 332, 411-415.