Modulation of MR-visible mobile lipid levels by cell culture conditions and correlations with chemotactic response

International Journal of Cancer

Volumn 65, Issue 2, 1996, Pages 238-245

  Delikatny, Edward J ^a   Lander, Catherine M ^a   Jeitner, Thomas M ^a,b   Hancock, Rebecca ^a   Mountford, Carolyn E ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

^b ALBANY MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLINE; GLYCEROPHOSPHORYLCHOLINE; LIPID; PHOSPHORYLCHOLINE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; FIBROBLAST; GROWTH INHIBITION; HUMAN CELL; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PH; PRIORITY JOURNAL; TUMOR CELL; VIRUS CELL TRANSFORMATION;

ANIMALS; CELL COUNT; CELL LINE, TRANSFORMED; CHEMOTAXIS; CULTURE MEDIA, SERUM-FREE; FIBROBLASTS; HYDROGEN-ION CONCENTRATION; LIPID METABOLISM; MAGNETIC RESONANCE SPECTROSCOPY; MICE;

EID: 0030045629     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(19960117)65:2<238::AID-IJC18>3.0.CO;2-9     Document Type: Article

References (24)

1. 1H NMR spectra of a myeloma cell line correlates with the induced formation of cytoplasmic lipid droplets. Magn. Reson. Med., 29, 546-550 (1993).
2. 31P NMR spectroscopy. J. biol. Chem., 262, 14875-14878 (1987).
3. DAVIS, B.H., WALTER, R.J., PEARSON, C.B., BECKER, E.L. and OLIVER, J.M., Membrane activity and topography of F-met-leu-phe-treated polymorphonuclear leukocytes. Amer. J. Pathol., 108, 206-216 (1982).
4. DELIKATNY, E.J., RUSSELL, P., HUNTER, J.C., HANCOCK, R., ATKINSON, K., VAN HAAFTEN-DAY, C. and MOUNTFORD, C.E., Proton MR and cervical neoplasia: ex vivo spectroscopy allows distinction of invasive carcinoma of the cervix from carcinoma in situ and other preinvasive lesions. Radiology, 188, 791-796 (1993).
5. DEVREOTES, P.N. and ZIGMOND, S.H., Chemotaxis of eukaryotic cells: a focus on leukocytes and Dictyostelium. Ann. Rev. Cell Biol., 4, 649-686 (1988).
6. DINGLEY, A.J., KING, N.J.C. and KING, G.F., An NMR investigation of the changes in plasma membrane triglyceride and phospholipid precursors during the activation of T-lymphocytes. Biochemistry, 31, 9098-9106 (1992).
7. FREITAS, I., PONTIGGIA, P., BARNI, S., BERTONE, V., PARENTE, M., NOVARINA, A., ROVETA, G., GERZELI, G. and STOWARD, P., Histochemical probes for the detection of hypoxic tumour cells. Anticancer Res., 10, 613-622 (1990).
8. GUIRGUIS, R., MARGULIES, I., TARABOLETTI, G., SCHIFFMANN, E. and LIOTTA, L., Cytokine-induced pseudopodial protrusion is coupled to tumour cell migration. Nature (Lond.), 329, 261-263 (1987).
9. HOLMES, K.T., DYNE, M., WILLIAMS, P.G., MAY, G.L., TRIFF, E., WRIGHT, L.C. and MOUNTFORD, C.E., Vinblastine sensitivity of leukaemic lymphoblasts modulated by serum lipid. FEBS Lett., 244, 103-107 (1989).
10. 1H magnetic resonance spectroscopy of primary human and murine cells of the myeloid lineage. ImmunoMethods, 4, 188-198 (1994).
11. 31P NMR studies of cultured human tumour cells: influence of pH on phospholipid metabolite levels and the detection of CDP-choline. NMR Biomed., 3, 78-89 (1990).
12. LAM, W.C., DELIKATNY, E.J., ORR, F.W., WASS, J., VARANI, J. and WARD, P.A., The chemotactic response of tumor cells: a model for cancer metastasis. Amer. J. Pathol., 104, 69-76 (1981).
13. LEAN, C.L., MACKINNON, W.B., DELIKATNY, E.J., WHITEHEAD, R.H. and MOUNTFORD, C.E., Cell-surface fucosylation and magnetic resonance spectroscopy characterization of human malignant colorectal cells. Biochemistry, 31, 11095-11105 (1992).
14. LECHNER, J.F. and LAVECK, M.A., A serum-free method for culturing normal human bronchial epithelial cells at clonal density. J. Tissue Cult Methods, 9, 43-48 (1985).
15. LE MOYEC, L., EUGENE, M., GAUVILLE, A., TATOUD, R., NGOE, B., CALVO, O. and CALVO, F., Lipid profiles of breast cancer cell lines: proton nuclear magnetic resonance spectroscopy. C.R. Acad. Sci. (Paris), 312, 25-30 (1992).
16. 1H magnetic resonance signals from malignant cells do not arise from intracellular lipid droplets. NMR Biomed., 2, 161-164 (1989).
17. MACKINNON, W.B., MAY, G.L. and MOUNTFORD, C.E., Esterified cholesterol and triglyceride are present in plasma membranes of Chinese hamster ovary cells. Europ. J. Biochem., 205, 827-839 (1992).
18. MOUNTFORD, C.E. and MACKINNON, W.B., Proton magnetic resonance spectroscopy of lymphocytes: an historical perspective. ImmunoMethods, 4, 98-112 (1994).
19. ORR, F.W., VARANI, J., DELIKATNY, E.J., JAIN, N. and WARD, P.A., Comparison of the chemotactic responsiveness of two fibrosarcoma populations of differing malignancy. Amer. J. Pathol., 102, 160-167 (1981).
20. PELECH, S.L. and VANCE, D.E., Regulation of phosphatidylcholine biosynthesis. Biochim. Biophys. Acta, 779, 217-251 (1984).
21. 1H MRS study. Proc. Soc. Magn. Reson., 2, 1323 (1994).
22. SMITH, T.A.D., ECCLES, S., ORMEROD, M.G., TOMBS, A.J., TITLEY, J.C. and LEACH, M.O., The phosphocholine and glycerophosphocholine content of an oestrogen sensitive rat mammary tumor correlates strongly with growth rate. Brit. J. Cancer, 64, 821-826 (1991).
23. TARABOLETTI, G., PERIN, L., BOTAZZI, B., MANTOVANI, A., GIAVAZZI, R. and SALMONA, M., Membrane fluidity affects tumour cell motility, invasion and lung colonizing potential. Int. J. Cancer, 44, 703-717 (1989).
24. WANG, T., MARQUARD, C. and FOKER, J., Aerobic glycolysis during lymphocyte proliferation. Nature (Lond.), 261, 703-705 (1976).