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Volumn 117, Issue 2, 1996, Pages 377-383

Cardiotoxicity of emetine dihydrochloride by calcium channel blockade in isolated preparations and ventricular myocytes of guinea-pig hearts

Author keywords

Cardiomyocyte; Cardiotoxicity; Emetine; Heart muscle preparations; L type calcium channel current

Indexed keywords

ANTIAMEBIC AGENT; BARIUM ION; CALCIUM CHANNEL; CALCIUM ION; EMETINE;

EID: 0030045545     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1476-5381.1996.tb15202.x     Document Type: Article
Times cited : (15)

References (38)
  • 2
    • 9544234812 scopus 로고
    • Inotropic and elect rophysiological actions of verapamil and D600 in mammalian myocardium. 1. Pattern of inotropic effects of the racemic compounds
    • BAYER, R., HENNEKSS, R., KAUFMANN, R, & MANNHOLD, R. (1975). Inotropic and elect rophysiological actions of verapamil and D600 in mammalian myocardium. 1. Pattern of inotropic effects of the racemic compounds. Naunyn Schmied. Arch. Pharmacol., 290, 49-68.
    • (1975) Naunyn Schmied. Arch. Pharmacol. , vol.290 , pp. 49-68
    • Bayer, R.1    Hennekss, R.2    Kaufmann, R.3    Mannhold, R.4
  • 3
    • 0017927911 scopus 로고
    • The effects of nifedipine on contraction and monophasic action potential of isolated cat myocardium
    • BAYER, R., RODENKIRCHEN, R., KAUFMANN, R., LEE, J.H. & HENNEKES, R. (1977). The effects of nifedipine on contraction and monophasic action potential of isolated cat myocardium. Naunyn Schmied. Arch. Pharmacol., 301, 29-37.
    • (1977) Naunyn Schmied. Arch. Pharmacol. , vol.301 , pp. 29-37
    • Bayer, R.1    Rodenkirchen, R.2    Kaufmann, R.3    Lee, J.H.4    Hennekes, R.5
  • 4
    • 0017370379 scopus 로고
    • Reconstruction of the action potential of ventricular myocardial fibres
    • BEELER, G.W. & REUTER, H. (1977). Reconstruction of the action potential of ventricular myocardial fibres. J. Physiol., 268, 177-210.
    • (1977) J. Physiol. , vol.268 , pp. 177-210
    • Beeler, G.W.1    Reuter, H.2
  • 6
    • 0014468852 scopus 로고
    • The effect of emetine on metabolism and contractility of the isolated rat heart
    • BRINK, A.J., KOTZÉ, J.C.N., MULLER, S.P. & LOCHNER, A. (1969). The effect of emetine on metabolism and contractility of the isolated rat heart. J. Pharmacol. Exp. Ther., 165, 251-257.
    • (1969) J. Pharmacol. Exp. Ther. , vol.165 , pp. 251-257
    • Brink, A.J.1    Kotzé, J.C.N.2    Muller, S.P.3    Lochner, A.4
  • 7
    • 0025615674 scopus 로고
    • Toxic mechanisms of the heart: A review
    • COMBS, A.B. & ACOSTA, D. (1990). Toxic mechanisms of the heart: a review. Toxicil. Pathol., 18, 583-596.
    • (1990) Toxicil. Pathol. , vol.18 , pp. 583-596
    • Combs, A.B.1    Acosta, D.2
  • 8
    • 0015945301 scopus 로고
    • Effect of verapamil on the normal action potential and on a calcium-dependent slow response of canine cardiac Purkinje fibres
    • CRANEFIELD, P.F., ARONSON, R.S. & WIT, A.L. (1974). Effect of verapamil on the normal action potential and on a calcium-dependent slow response of canine cardiac Purkinje fibres. Circ. Res., 34, 204-213.
    • (1974) Circ. Res. , vol.34 , pp. 204-213
    • Cranefield, P.F.1    Aronson, R.S.2    Wit, A.L.3
  • 10
    • 0024830831 scopus 로고
    • Kinetic properties of the cardiac T-type calcium channel in the guinea-pig
    • DROOGMANS, G. & NILIUS, B. (1989). Kinetic properties of the cardiac T-type calcium channel in the guinea-pig. J. Physiol., 419, 627-650.
    • (1989) J. Physiol. , vol.419 , pp. 627-650
    • Droogmans, G.1    Nilius, B.2
  • 11
    • 0020000227 scopus 로고
    • Sodium and calcium channels in bovine chromaffin cells
    • FENWICK, E.M., MARTY, A. & NEHER, K. (1982). Sodium and calcium channels in bovine chromaffin cells. J. Physiol., 331, 599-635.
    • (1982) J. Physiol. , vol.331 , pp. 599-635
    • Fenwick, E.M.1    Marty, A.2    Neher, K.3
  • 12
    • 0017432208 scopus 로고
    • Specific pharmacology of calcium in myocardium, cardiac pacemakers, and vascular smooth muscle
    • FLECKENSTEIN, A. (1977). Specific pharmacology of calcium in myocardium, cardiac pacemakers, and vascular smooth muscle. Anna. Rev. Pharmacol. Topical., 17, 149-166.
    • (1977) Anna. Rev. Pharmacol. Topical. , vol.17 , pp. 149-166
    • Fleckenstein, A.1
  • 13
    • 0021253728 scopus 로고
    • Death from ipecac intoxication in a patient with anorexia nervosa
    • FRIEDMAN, E.J. (1984). Death from ipecac intoxication in a patient with anorexia nervosa. Am. J. Psychiatry, 141, 702-703.
    • (1984) Am. J. Psychiatry , vol.141 , pp. 702-703
    • Friedman, E.J.1
  • 14
    • 0020630748 scopus 로고
    • A comparative study of the blockade of calcium-dependent action potentials by verapamil, nifedipine and nimodipine in ventricular muscle
    • HACHISU, M. & PAPPANO, A.J. (1983). A comparative study of the blockade of calcium-dependent action potentials by verapamil, nifedipine and nimodipine in ventricular muscle. J. Pharmacol. Exp. Ther., 225, 112-120.
    • (1983) J. Pharmacol. Exp. Ther. , vol.225 , pp. 112-120
    • Hachisu, M.1    Pappano, A.J.2
  • 15
    • 0019441262 scopus 로고
    • Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches
    • HAMILL, O.P., MARTY, A., NEHER, E., SAKMANN, B. & SIGWORTH, F.J. (1981). Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflügers Arch., 391, 85-100.
    • (1981) Pflügers Arch. , vol.391 , pp. 85-100
    • Hamill, O.P.1    Marty, A.2    Neher, E.3    Sakmann, B.4    Sigworth, F.J.5
  • 16
    • 0021182780 scopus 로고
    • Different modes of Ca channel gating behaviour favoured by dihydropyridine Ca agonists and antagonists
    • HESS, P., LANSMAN, J.B. & TSIEN, R. (1984). Different modes of Ca channel gating behaviour favoured by dihydropyridine Ca agonists and antagonists. Nature, 311, 538-544.
    • (1984) Nature , vol.311 , pp. 538-544
    • Hess, P.1    Lansman, J.B.2    Tsien, R.3
  • 17
    • 0021417444 scopus 로고
    • Delayed rectification in the cardiac Purkinje fibre is not activated by intracellular calcium
    • KASS, R.S. (1982). Delayed rectification in the cardiac Purkinje fibre is not activated by intracellular calcium. Biophys. J., 45, 837-839.
    • (1982) Biophys. J. , vol.45 , pp. 837-839
    • Kass, R.S.1
  • 18
    • 0019908229 scopus 로고
    • Nisoldipine: A new, more selective calcium current blocker in cardiac Purkinje fibres
    • KASS, R.S. (1984). Nisoldipine: a new, more selective calcium current blocker in cardiac Purkinje fibres. J. Pharmacol. Exp. Ther., 223, 446-456.
    • (1984) J. Pharmacol. Exp. Ther. , vol.223 , pp. 446-456
    • Kass, R.S.1
  • 19
    • 0019512619 scopus 로고
    • Comparative effects of three calcium antagonists, diltiazem, verapamil, and nifedipine, on the sinoatrial and atrioventricular nodes
    • KAWAI, C., KONISHI, T., MATSUYAMA, F., & OKAZAKI, H. (1981). Comparative effects of three calcium antagonists, diltiazem, verapamil, and nifedipine, on the sinoatrial and atrioventricular nodes. Circulation, 63, 1035-1042.
    • (1981) Circulation , vol.63 , pp. 1035-1042
    • Kawai, C.1    Konishi, T.2    Matsuyama, F.3    Okazaki, H.4
  • 20
    • 0023778229 scopus 로고
    • Voltage-dependent decrease in the availability of single calcium channels by nitrendipinc in guinea-pig ventricular cells
    • KAWASHIMA, Y. & OCHI, R. (1988). Voltage-dependent decrease in the availability of single calcium channels by nitrendipinc in guinea-pig ventricular cells. J. Physiol., 402, 219-235.
    • (1988) J. Physiol. , vol.402 , pp. 219-235
    • Kawashima, Y.1    Ochi, R.2
  • 22
    • 9044224077 scopus 로고
    • Selective inhibition of Ca conductivity of mammalian cardiac fibre membranes by Ca-antagonistic compounds (verapamil, D600)
    • Munich 1971. Munich: German Physiological Society
    • KOHLHARDT, M., BAUER, B., KRAUSE, H. & FLECKENSTEIN, A. (1971). Selective inhibition of Ca conductivity of mammalian cardiac fibre membranes by Ca-antagonistic compounds (verapamil, D600). In Proceedings of the 25th Congress of the International Union of Physiological Sciences, Munich 1971, Vol. 9, p. 313. Munich: German Physiological Society.
    • (1971) Proceedings of the 25th Congress of the International Union of Physiological Sciences , vol.9 , pp. 313
    • Kohlhardt, M.1    Bauer, B.2    Krause, H.3    Fleckenstein, A.4
  • 23
    • 0024307517 scopus 로고
    • Reversible emetine-induced myopathy with ECG abnormalities: A toxic myopathy
    • KUNTZER, T., BOGOUSSLAVSKY, J., DERUAZ, J.P., JANZER, R. & REGLI, K. (1989). Reversible emetine-induced myopathy with ECG abnormalities: a toxic myopathy. J. Neurol., 236, 246-248.
    • (1989) J. Neurol. , vol.236 , pp. 246-248
    • Kuntzer, T.1    Bogousslavsky, J.2    Deruaz, J.P.3    Janzer, R.4    Regli, K.5
  • 24
    • 0020536822 scopus 로고
    • Mechanism of calcium channel blockade by verapamil, D600, diltiazem and nitrendipine in single dialysed heart cells
    • LEE, K.S. & TSIEN, R.W. (1983). Mechanism of calcium channel blockade by verapamil, D600, diltiazem and nitrendipine in single dialysed heart cells. Nature, 302, 790-794.
    • (1983) Nature , vol.302 , pp. 790-794
    • Lee, K.S.1    Tsien, R.W.2
  • 25
    • 0025353605 scopus 로고
    • La cardiotossicita dell'emetina
    • MARINO, A., COSTA, R. & DE NATALE, G. (1990). La cardiotossicita dell'emetina. Clin. Ter., 133, 131-143.
    • (1990) Clin. Ter. , vol.133 , pp. 131-143
    • Marino, A.1    Costa, R.2    De Natale, G.3
  • 28
    • 0022148018 scopus 로고
    • A uniform enzymatic method for dissociation of myocytes from heart and stomachs of vertebrates
    • MITRA, R. & MORAD, M. (1985). A uniform enzymatic method for dissociation of myocytes from heart and stomachs of vertebrates. Am. J. Physiol., 249, H1056-1060.
    • (1985) Am. J. Physiol. , vol.249
    • Mitra, R.1    Morad, M.2
  • 29
    • 0024393890 scopus 로고
    • Regulation of calcium release is gated by calcium current, not gating charge, in cardiac myocytes
    • NABAUER, M., CALLEWAERT, G., CLEEMANN, L. & MORAD, M. (1989). Regulation of calcium release is gated by calcium current, not gating charge, in cardiac myocytes. Science, 244, 800-803.
    • (1989) Science , vol.244 , pp. 800-803
    • Nabauer, M.1    Callewaert, G.2    Cleemann, L.3    Morad, M.4
  • 30
    • 0016653440 scopus 로고
    • Effect of diltiazem on electrical and mechanical activity of isolated cardiac ventricular muscle of guinea pig
    • NAKAJIMA, H., HOSHIYAMA, M., YAMASHITA, K. & KIYOMOTO, A. (1975). Effect of diltiazem on electrical and mechanical activity of isolated cardiac ventricular muscle of guinea pig. Jpn. J. Pharmacol., 25, 383-392.
    • (1975) Jpn. J. Pharmacol. , vol.25 , pp. 383-392
    • Nakajima, H.1    Hoshiyama, M.2    Yamashita, K.3    Kiyomoto, A.4
  • 31
    • 0022346398 scopus 로고
    • Reversible myopathy secondary to abuse of ipecac in patients with major eating disorders
    • PALMER, E.P. & GUAY, A.T. (1985). Reversible myopathy secondary to abuse of ipecac in patients with major eating disorders. New Engl. J. Med., 313, 1457-1459.
    • (1985) New Engl. J. Med. , vol.313 , pp. 1457-1459
    • Palmer, E.P.1    Guay, A.T.2
  • 32
    • 0014134844 scopus 로고
    • Die Wertbestimmung inotrop wirkender Arzneimittel am isolierten Papillarmuskel
    • REITER, M. (1967). Die Wertbestimmung inotrop wirkender Arzneimittel am isolierten Papillarmuskel. Arzneim. Forsch., 17, 1249-1253.
    • (1967) Arzneim. Forsch. , vol.17 , pp. 1249-1253
    • Reiter, M.1
  • 33
    • 0015045256 scopus 로고
    • Observations on the hypotensive response to dehydroemetine
    • SALAKO, L.A. & DUROTOYE, A.O. (1971). Observations on the hypotensive response to dehydroemetine. Eur. J. Pharmacol., 14, 200-203.
    • (1971) Eur. J. Pharmacol. , vol.14 , pp. 200-203
    • Salako, L.A.1    Durotoye, A.O.2
  • 35
    • 9044232932 scopus 로고
    • Ipecacuanha-Alkaloide
    • Berlin, Heidelberg, New York, London, Paris, Toyko, Hong Kong, Barcelona, Budapest: Springer Verlag
    • STEINEGGER, E. & HANSEL, R. (1992). Ipecacuanha-Alkaloide. In Pharmakognosie, Vol. 5, pp. 536-539. Berlin, Heidelberg, New York, London, Paris, Toyko, Hong Kong, Barcelona, Budapest: Springer Verlag.
    • (1992) Pharmakognosie , vol.5 , pp. 536-539
    • Steinegger, E.1    Hansel, R.2
  • 36
    • 0027431420 scopus 로고
    • Het amoeboom van de dikke darm en het rectum
    • STUIVER, P.C. & VISSER, L.G. (1993). Het amoeboom van de dikke darm en het rectum. Ned. Tijdschr. Geneeskd., 137, 2328-2331.
    • (1993) Ned. Tijdschr. Geneeskd. , vol.137 , pp. 2328-2331
    • Stuiver, P.C.1    Visser, L.G.2
  • 37
    • 0025210005 scopus 로고
    • Calcium-sensitive delayed rectifier potassium current in guinea pig ventricular cells
    • Heart Circ. Physiol. 27
    • TOHSE, N. (1990). Calcium-sensitive delayed rectifier potassium current in guinea pig ventricular cells. Am. J. Physiol., 258, (Heart Circ. Physiol. 27), H1200-H1207.
    • (1990) Am. J. Physiol. , vol.258
    • Tohse, N.1


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